Cytoglobin: Key player in preventing liver disease

by Osaka City University6His tagged recombinant human CYGB (His-CYGB) was endocytosed into the HSCs via Clathrin-mediated pathway, scavenged ROS, such as O2- and OH-, and induced IFN-β secretion media

Updated on: May 09,2024 5

Cytoglobin: Key player in preventing liver disease

by Osaka City University6His tagged recombinant human CYGB (His-CYGB) was endocytosed into the HSCs via Clathrin-mediated pathway, scavenged ROS, such as O2- and OH-, and induced IFN-β secretion media

Updated on:May 09,2024 5

Two-organ chip developed to answer fatty liver questions

by Kyoto UniversityThe interaction between the small intestine and the liver of patients with non-alcoholic fatty liver disease (NAFLD) has been reproduced on a small chip. Credit: Mindy Takamiya

Updated on: May 29,2024 6

Two-organ chip developed to answer fatty liver questions

by Kyoto UniversityThe interaction between the small intestine and the liver of patients with non-alcoholic fatty liver disease (NAFLD) has been reproduced on a small chip. Credit: Mindy Takamiya

Updated on:May 29,2024 6

A novel malaria vaccine vector that targets the liver

by Kanazawa UniversityThe IVIS imaging results for the livers collected from mice on day 8 or day 224 post-administration of AAV-Luc showed that systemic administration of AAV8 induced ~24–43 tim

Updated on: March 25,2024 10

A novel malaria vaccine vector that targets the liver

by Kanazawa UniversityThe IVIS imaging results for the livers collected from mice on day 8 or day 224 post-administration of AAV-Luc showed that systemic administration of AAV8 induced ~24–43 tim

Updated on:March 25,2024 10

New combination therapy offers chance of healing hepatitis B

by German Center for Infection ResearchThe digitally-colorized transmission electron microscopic image reveals the presence of Hepatitis B virions (orange colored). Credit: CDC/Dr. Erskine PalmerAroun

Updated on: May 06,2024 10

New combination therapy offers chance of healing hepatitis B

by German Center for Infection ResearchThe digitally-colorized transmission electron microscopic image reveals the presence of Hepatitis B virions (orange colored). Credit: CDC/Dr. Erskine PalmerAroun

Updated on:May 06,2024 10

New standards to quantify hepatitis B virus reservoirs in liver cells

by Nicola Wittekindt, Deutsches Zentrum für InfektionsforschungThe effect of different DNA extraction methods on cccDNA quantification by qPCR and SB in HBV-infected USG mouse liver tissue. (A) Schema

Updated on: May 29,2024 7

New standards to quantify hepatitis B virus reservoirs in liver cells

by Nicola Wittekindt, Deutsches Zentrum für InfektionsforschungThe effect of different DNA extraction methods on cccDNA quantification by qPCR and SB in HBV-infected USG mouse liver tissue. (A) Schema

Updated on:May 29,2024 7

Researchers identify a potential therapeutic target against cirrhosis and liver inflammation

by University of BarcelonaA new study by a team of the University of Barcelona could promote the design of drugs to treat these pathologies. Credit: University of BarcelonaThe RNF41 protein could

Updated on: January 29,2024 12

Researchers identify a potential therapeutic target against cirrhosis and liver inflammation

by University of BarcelonaA new study by a team of the University of Barcelona could promote the design of drugs to treat these pathologies. Credit: University of BarcelonaThe RNF41 protein could

Updated on:January 29,2024 12

Noninvasive biomarker tests could be alternatives to painful liver biopsies

by A.J. Hostetler,Virginia Commonwealth UniversityCredit: Unsplash/CC0 Public DomainLed by the director of Virginia Commonwealth University's Stravitz-Sanyal Institute of Liver Disease and M

Updated on: May 09,2024 6

Noninvasive biomarker tests could be alternatives to painful liver biopsies

by A.J. Hostetler,Virginia Commonwealth UniversityCredit: Unsplash/CC0 Public DomainLed by the director of Virginia Commonwealth University's Stravitz-Sanyal Institute of Liver Disease and M

Updated on:May 09,2024 6

Team performs the first gene therapy tests in a whole human liver

by Children's Medical Research InstituteCredit: Pixabay/CC0 Public DomainIn a worldwide first-of-its-kind study published in the journalNature Communicationsthis week, a team of scient

Updated on: March 20,2024 13

Team performs the first gene therapy tests in a whole human liver

by Children's Medical Research InstituteCredit: Pixabay/CC0 Public DomainIn a worldwide first-of-its-kind study published in the journalNature Communicationsthis week, a team of scient

Updated on:March 20,2024 13

Hepatitis C virus infection: Research team discovers that a protein has an unexpected proviral effect

by Susanne Stöcker, Paul-Ehrlich-Institut - Bundesinstitut für Impfstoffe und biomedizinische ArzneimittelThe expression of GBP1 is increased in HCV replicating cells. Credit:PLOS Pathogens&nbsp

Updated on: March 27,2024 0

Hepatitis C virus infection: Research team discovers that a protein has an unexpected proviral effect

by Susanne Stöcker, Paul-Ehrlich-Institut - Bundesinstitut für Impfstoffe und biomedizinische ArzneimittelThe expression of GBP1 is increased in HCV replicating cells. Credit:PLOS Pathogens&nbsp

Updated on:March 27,2024 0

Exposure to toxic blue-green algae, exacerbated by climate change, shown to cause liver disease in mouse models

by University of California, IrvineCYN exposure in mice for 15 days via oral gavage caused an altered gut bacteriome pattern at both phylum and family levels with decreased α-diversity. (A) The r

Updated on: March 25,2024 11

Exposure to toxic blue-green algae, exacerbated by climate change, shown to cause liver disease in mouse models

by University of California, IrvineCYN exposure in mice for 15 days via oral gavage caused an altered gut bacteriome pattern at both phylum and family levels with decreased α-diversity. (A) The r

Updated on:March 25,2024 11

Using social determinants of health to guide liver disease screening

by Ariana Baldassano,Rush University Medical CenterCredit:JHEP Reports(2023). DOI: 10.1016/j.jhepr.2023.100696Black people face a higher risk of developing severe liver fibrosis, but

Updated on: May 29,2024 8

Using social determinants of health to guide liver disease screening

by Ariana Baldassano,Rush University Medical CenterCredit:JHEP Reports(2023). DOI: 10.1016/j.jhepr.2023.100696Black people face a higher risk of developing severe liver fibrosis, but

Updated on:May 29,2024 8

Gut bacteria are crucial for liver repair, finds study

by Technical University MunichGut bacteria in a Petri dish: Our microbiome influences a great number of processes in the human body. A recent study shows that the liver's regenerative capacit

Updated on: April 20,2024 11

Gut bacteria are crucial for liver repair, finds study

by Technical University MunichGut bacteria in a Petri dish: Our microbiome influences a great number of processes in the human body. A recent study shows that the liver's regenerative capacit

Updated on:April 20,2024 11