Exploring how the liver immune system eats up 'bad cholesterol'

by Karolinska InstitutetCredit: CC0 Public DomainA new study from Karolinska Institutet in Sweden reveals that immune cells in the liver react to high cholesterol levels and eat up excess cholest

Updated on: March 20,2024 14

Exploring how the liver immune system eats up 'bad cholesterol'

by Karolinska InstitutetCredit: CC0 Public DomainA new study from Karolinska Institutet in Sweden reveals that immune cells in the liver react to high cholesterol levels and eat up excess cholest

Updated on:March 20,2024 14

Team performs the first gene therapy tests in a whole human liver

by Children's Medical Research InstituteCredit: Pixabay/CC0 Public DomainIn a worldwide first-of-its-kind study published in the journalNature Communicationsthis week, a team of scient

Updated on: March 20,2024 13

Team performs the first gene therapy tests in a whole human liver

by Children's Medical Research InstituteCredit: Pixabay/CC0 Public DomainIn a worldwide first-of-its-kind study published in the journalNature Communicationsthis week, a team of scient

Updated on:March 20,2024 13

New insights into genetic mechanisms could improve treatment of liver fibrosis

by CeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesGraphical abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.109301The liver is not only the larges

Updated on: March 20,2024 18

New insights into genetic mechanisms could improve treatment of liver fibrosis

by CeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesGraphical abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.109301The liver is not only the larges

Updated on:March 20,2024 18

Mechanism for silencing gene expression targets the culprit behind a deadly liver cancer

by Sanford M. Simon,Rockefeller UniversityASGR1 in FLC. (A) RNA expression analysis of ASGR1 across patient samples. (B) Immunofluorescence of ASGR1 in tumor-adjacent healthy liver, primary tumo

Updated on: March 20,2024 10

Mechanism for silencing gene expression targets the culprit behind a deadly liver cancer

by Sanford M. Simon,Rockefeller UniversityASGR1 in FLC. (A) RNA expression analysis of ASGR1 across patient samples. (B) Immunofluorescence of ASGR1 in tumor-adjacent healthy liver, primary tumo

Updated on:March 20,2024 10

Overcoming barriers to conducting clinical trials in childhood rare disease research

FEBRUARY 29, 2024byThe Hospital for Sick ChildrenGraphical abstract. Credit:Hepatology(2023). DOI: 10.1097/HEP.0000000000000727Using a novel methodology, researchers at The Hospital

Updated on: March 15,2024 5

Overcoming barriers to conducting clinical trials in childhood rare disease research

FEBRUARY 29, 2024byThe Hospital for Sick ChildrenGraphical abstract. Credit:Hepatology(2023). DOI: 10.1097/HEP.0000000000000727Using a novel methodology, researchers at The Hospital

Updated on:March 15,2024 5

Multiple myeloma cured after hepatitis treatment reveals that this cancer can be caused by viruses

JANUARY 19, 2024byThe Spanish National Cancer Research CentreThe effect of antiviral treatment in hepatitis C virus- and hepatitis B virus-infected multiple myeloma cohorts. (A) Study design and

Updated on: March 15,2024 7

Multiple myeloma cured after hepatitis treatment reveals that this cancer can be caused by viruses

JANUARY 19, 2024byThe Spanish National Cancer Research CentreThe effect of antiviral treatment in hepatitis C virus- and hepatitis B virus-infected multiple myeloma cohorts. (A) Study design and

Updated on:March 15,2024 7

Advancing noninvasive diagnosis of NASH: Potential of sequential ultrasound molecular imaging in NAFLD/MAFLD

by KeAi Communications Co.Animal study flowchart and schematic illustration of sequential USMI. Credit:Liver Research(2023). DOI: 10.1016/j.livres.2023.11.002Non-alcoholic fatty liver dise

Updated on: March 07,2024 10

Advancing noninvasive diagnosis of NASH: Potential of sequential ultrasound molecular imaging in NAFLD/MAFLD

by KeAi Communications Co.Animal study flowchart and schematic illustration of sequential USMI. Credit:Liver Research(2023). DOI: 10.1016/j.livres.2023.11.002Non-alcoholic fatty liver dise

Updated on:March 07,2024 10

Researchers identify a potential therapeutic target against cirrhosis and liver inflammation

by University of BarcelonaA new study by a team of the University of Barcelona could promote the design of drugs to treat these pathologies. Credit: University of BarcelonaThe RNF41 protein could

Updated on: January 29,2024 12

Researchers identify a potential therapeutic target against cirrhosis and liver inflammation

by University of BarcelonaA new study by a team of the University of Barcelona could promote the design of drugs to treat these pathologies. Credit: University of BarcelonaThe RNF41 protein could

Updated on:January 29,2024 12

Markers of inflammation can predict 180-day mortality in cirrhosis

by Elana GotkineFor patients with newly diagnosed cirrhosis, markers of inflammation can predict 180-day mortality, but not liver-related admissions, according to a study published online Nov. 16 in&n

Updated on: January 29,2024 16

Markers of inflammation can predict 180-day mortality in cirrhosis

by Elana GotkineFor patients with newly diagnosed cirrhosis, markers of inflammation can predict 180-day mortality, but not liver-related admissions, according to a study published online Nov. 16 in&n

Updated on:January 29,2024 16

Novel insights into HBV-hepatocellular carcinoma at single-cell sequencing

by Sichuan International Medical Exchange and Promotion AssociationThe intricate immune microenvironment, tumor cell plasticity, and dynamics of tumor evolution pose daunting challenges to the definit

Updated on: January 26,2024 17

Novel insights into HBV-hepatocellular carcinoma at single-cell sequencing

by Sichuan International Medical Exchange and Promotion AssociationThe intricate immune microenvironment, tumor cell plasticity, and dynamics of tumor evolution pose daunting challenges to the definit

Updated on:January 26,2024 17

Researchers reveal uncharted liver-focused pathway in gene therapy immune responses

byIndiana University School of MedicineGraphical Abstract. Credit:Molecular Therapy(2023). DOI: 10.1016/j.ymthe.2023.11.029Indiana University School of Medicine researchers have unco

Updated on: January 26,2024 12

Researchers reveal uncharted liver-focused pathway in gene therapy immune responses

byIndiana University School of MedicineGraphical Abstract. Credit:Molecular Therapy(2023). DOI: 10.1016/j.ymthe.2023.11.029Indiana University School of Medicine researchers have unco

Updated on:January 26,2024 12

New hope for patients with non-alcoholic fatty liver disease

byUniversity of MontrealCredit:Metabolism(2023). DOI: 10.1016/j.metabol.2023.155736Non-alcoholic fatty liver disease (NAFLD) is a major health problem affecting approximately 30% of

Updated on: January 25,2024 12

New hope for patients with non-alcoholic fatty liver disease

byUniversity of MontrealCredit:Metabolism(2023). DOI: 10.1016/j.metabol.2023.155736Non-alcoholic fatty liver disease (NAFLD) is a major health problem affecting approximately 30% of

Updated on:January 25,2024 12