How does vaccination thwart pneumococcal infection? Animal model uncovers 'capture and kill' scenario

by Delthia Ricks , Medical XpressRepresentative IVM imaging of vaccine-activated capture of ST865 pneumococci in the liver sinusoids. Pneumococci, green; KCs, red; ECs, cyan; neutrophils, magenta. Cre

Updated on: March 07,2024

How does vaccination thwart pneumococcal infection? Animal model uncovers 'capture and kill' scenario

by Delthia Ricks , Medical XpressRepresentative IVM imaging of vaccine-activated capture of ST865 pneumococci in the liver sinusoids. Pneumococci, green; KCs, red; ECs, cyan; neutrophils, magenta. Cre

Updated on:March 07,2024

A key gene modifies regulatory T cells to fine-tune the immune response

by Salk InstituteA histology image showing inflammation in colon epithelium. Weakening of regulatory T cell function induces infiltration of immune cells (small blue dots) into colon epithelium (

Updated on: May 07,2024

A key gene modifies regulatory T cells to fine-tune the immune response

by Salk InstituteA histology image showing inflammation in colon epithelium. Weakening of regulatory T cell function induces infiltration of immune cells (small blue dots) into colon epithelium (

Updated on:May 07,2024

TAp63: A new protein drug target for rheumatoid arthritis

by Chiba UniversityGraphical abstract. Credit:JCI Insight(2023). DOI: 10.1172/jci.insight.164778Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The

Updated on: May 08,2024

TAp63: A new protein drug target for rheumatoid arthritis

by Chiba UniversityGraphical abstract. Credit:JCI Insight(2023). DOI: 10.1172/jci.insight.164778Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The

Updated on:May 08,2024

COVID-19: Biomarkers linked to severe forms of the disease

by University of MontrealColorized scanning electron micrograph of an apoptotic cell (green) heavily infected with SARS-COV-2 virus particles (yellow), isolated from a patient sample. Image captu

Updated on: April 13,2024

COVID-19: Biomarkers linked to severe forms of the disease

by University of MontrealColorized scanning electron micrograph of an apoptotic cell (green) heavily infected with SARS-COV-2 virus particles (yellow), isolated from a patient sample. Image captu

Updated on:April 13,2024

Methotrexate improves function in people with knee OA after three months

by American College of RheumatologyCredit: CC0 Public DomainA new study presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that after three months of t

Updated on: May 13,2024

Methotrexate improves function in people with knee OA after three months

by American College of RheumatologyCredit: CC0 Public DomainA new study presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that after three months of t

Updated on:May 13,2024

Anti-cancer virus fits tumor receptor like a 'key in a lock'

by Okinawa Institute of Science and TechnologyA cryo-EM map of the receptor decorated capsid in which a single protomer was replaced with the atomic model. Seneca Valley Virus capsid proteins are

Updated on: April 08,2024

Anti-cancer virus fits tumor receptor like a 'key in a lock'

by Okinawa Institute of Science and TechnologyA cryo-EM map of the receptor decorated capsid in which a single protomer was replaced with the atomic model. Seneca Valley Virus capsid proteins are

Updated on:April 08,2024

Suppressing graft-versus-host disease using immunosuppressive iPS cell-derived regulatory T cells

by Kyoto UniversityGraphical abstract. Credit:Cell Stem Cell(2024). DOI: 10.1016/j.stem.2024.05.004A recent study by a team led by Professor Shin Kaneko successfully induced regulator

Updated on: June 15,2024

Suppressing graft-versus-host disease using immunosuppressive iPS cell-derived regulatory T cells

by Kyoto UniversityGraphical abstract. Credit:Cell Stem Cell(2024). DOI: 10.1016/j.stem.2024.05.004A recent study by a team led by Professor Shin Kaneko successfully induced regulator

Updated on:June 15,2024

Macrophages produce heat from brown adipose tissue in response to cold, study reveals

by University of TsukubaGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113978Researchers from University of Tsukuba have elucidated the molecular mechanism

Updated on: March 27,2024

Macrophages produce heat from brown adipose tissue in response to cold, study reveals

by University of TsukubaGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113978Researchers from University of Tsukuba have elucidated the molecular mechanism

Updated on:March 27,2024

How IL-6 allows the immune response to develop for a key cell, the T follicular helper

by Jeff Hansen,University of Alabama at BirminghamAndre Ballesteros-Tato. Credit: UABThe body's immune response fights against infectious disease, and it safeguards against future infections

Updated on: April 16,2024

How IL-6 allows the immune response to develop for a key cell, the T follicular helper

by Jeff Hansen,University of Alabama at BirminghamAndre Ballesteros-Tato. Credit: UABThe body's immune response fights against infectious disease, and it safeguards against future infections

Updated on:April 16,2024

Does an elevated immune response to a gut bacterial protein contribute to rheumatoid arthritis?

by WileyCredit: Unsplash/CC0 Public DomainRheumatoid arthritis is a chronic autoimmune disease that is associated with aberrant immune responses. In a recent analysis published inArthritis

Updated on: June 15,2024

Does an elevated immune response to a gut bacterial protein contribute to rheumatoid arthritis?

by WileyCredit: Unsplash/CC0 Public DomainRheumatoid arthritis is a chronic autoimmune disease that is associated with aberrant immune responses. In a recent analysis published inArthritis

Updated on:June 15,2024

Rheumatoid arthritis finding may lead to new inflammation blockers

by Sara Tiner,Mayo ClinicCredit: Unsplash/CC0 Public DomainMayo Clinic researchers have linked the T cell dysfunction seen in rheumatoid arthritis with a metabolic deficiency, reported in a new&

Updated on: May 29,2024

Rheumatoid arthritis finding may lead to new inflammation blockers

by Sara Tiner,Mayo ClinicCredit: Unsplash/CC0 Public DomainMayo Clinic researchers have linked the T cell dysfunction seen in rheumatoid arthritis with a metabolic deficiency, reported in a new&

Updated on:May 29,2024

Early knee arthritis symptoms first felt when using stairs

by University of LeedsPeople who suffer from knee pain when using the stairs may be experiencing the early symptoms of osteoarthritis, according to a new University of Leeds study.The research, p

Updated on: March 28,2024

Early knee arthritis symptoms first felt when using stairs

by University of LeedsPeople who suffer from knee pain when using the stairs may be experiencing the early symptoms of osteoarthritis, according to a new University of Leeds study.The research, p

Updated on:March 28,2024