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Immunology & Rheumatology
Focuses on rheumatic and immune diseases.
Sub Categories on Immunology & Rheumatology
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Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P
HSPC-derived CAR T-cells capable of lasting engraftment

HSPC-derived CAR T-cells capable of lasting engraftment

(HealthDay)—Hematopoietic stem/progenitor cell (HSPC)-derived chimeric antigen receptor (CAR) T-cells are capable of long-term engraftment in a model of HIV/AIDS, according to a study published online

HSPC-derived CAR T-cells capable of lasting engraftment

(HealthDay)—Hematopoietic stem/progenitor cell (HSPC)-derived chimeric antigen receptor (CAR) T-cells are capable of long-term engraftment in a model of HIV/AIDS, according to a study published online
Scientists discover two cellular defects appear to drive disease in lupus

Scientists discover two cellular defects appear to drive disease in lupus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine and Brigham and Women's Hospital scientists have discovered a molecular defect that promotes the pathologic im

Scientists discover two cellular defects appear to drive disease in lupus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine and Brigham and Women's Hospital scientists have discovered a molecular defect that promotes the pathologic im
Mast cell levels may explain sex differences in osteoarthritis pain

Mast cell levels may explain sex differences in osteoarthritis pain

by Hospital for Special SurgeryCredit: Pixabay/CC0 Public DomainInvestigators at Hospital for Special Surgery (HSS) have discovered that at the time of total knee replacement, women have signific

Mast cell levels may explain sex differences in osteoarthritis pain

by Hospital for Special SurgeryCredit: Pixabay/CC0 Public DomainInvestigators at Hospital for Special Surgery (HSS) have discovered that at the time of total knee replacement, women have signific
Rheumatoid arthritis finding may lead to new inflammation blockers

Rheumatoid arthritis finding may lead to new inflammation blockers

by Sara Tiner,Mayo ClinicCredit: Unsplash/CC0 Public DomainMayo Clinic researchers have linked the T cell dysfunction seen in rheumatoid arthritis with a metabolic deficiency, reported in a new&

Rheumatoid arthritis finding may lead to new inflammation blockers

by Sara Tiner,Mayo ClinicCredit: Unsplash/CC0 Public DomainMayo Clinic researchers have linked the T cell dysfunction seen in rheumatoid arthritis with a metabolic deficiency, reported in a new&
Allergies may plague renters more than homeowners

Allergies may plague renters more than homeowners

Those who rent less likely to take steps to reduce indoor allergy triggers, study finds .(HealthDay) -- People with common indoor allergies who rent their home are much less likely than homeowners to

Allergies may plague renters more than homeowners

Those who rent less likely to take steps to reduce indoor allergy triggers, study finds .(HealthDay) -- People with common indoor allergies who rent their home are much less likely than homeowners to
A protein that controls inflammation

A protein that controls inflammation

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainA study by the research team of Prof. Geert van Loo (VIB-UGent Center for Inflammation Research) has unraveled a critical

A protein that controls inflammation

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainA study by the research team of Prof. Geert van Loo (VIB-UGent Center for Inflammation Research) has unraveled a critical
How IL-6 allows the immune response to develop for a key cell, the T follicular helper

How IL-6 allows the immune response to develop for a key cell, the T follicular helper

by Jeff Hansen,University of Alabama at BirminghamAndre Ballesteros-Tato. Credit: UABThe body's immune response fights against infectious disease, and it safeguards against future infections

How IL-6 allows the immune response to develop for a key cell, the T follicular helper

by Jeff Hansen,University of Alabama at BirminghamAndre Ballesteros-Tato. Credit: UABThe body's immune response fights against infectious disease, and it safeguards against future infections
Anaphylaxis treatment remains confusing for patients, caregivers and emergency personnel, research finds

Anaphylaxis treatment remains confusing for patients, caregivers and emergency personnel, research finds

byAmerican College of Allergy, Asthma, and ImmunologyCredit: Unsplash/CC0 Public DomainAnaphylaxis can come on suddenly and without warning, and because its symptoms can be fatal, it is scary fo

Anaphylaxis treatment remains confusing for patients, caregivers and emergency personnel, research finds

byAmerican College of Allergy, Asthma, and ImmunologyCredit: Unsplash/CC0 Public DomainAnaphylaxis can come on suddenly and without warning, and because its symptoms can be fatal, it is scary fo
Air pollution exposure tied to new psoriasis

Air pollution exposure tied to new psoriasis

by Lori SolomonLong-term exposure to air pollution is associated with the development of new psoriasis, according to a studypublishedonline July 16 inJAMA Network Open.Junhui Wu, Ph.

Air pollution exposure tied to new psoriasis

by Lori SolomonLong-term exposure to air pollution is associated with the development of new psoriasis, according to a studypublishedonline July 16 inJAMA Network Open.Junhui Wu, Ph.
Researchers pursuing arthritis protein

Researchers pursuing arthritis protein

by University of CopenhagenThe healthy blood cells stem from the blood bank at Rigshospitalet in Copenhagen, and more than 50 donors have been examined with the same result. Credit: Blood cells,

Researchers pursuing arthritis protein

by University of CopenhagenThe healthy blood cells stem from the blood bank at Rigshospitalet in Copenhagen, and more than 50 donors have been examined with the same result. Credit: Blood cells,
Warfarin use significantly increases risk of knee and hip replacement in people with OA

Warfarin use significantly increases risk of knee and hip replacement in people with OA

by American College of RheumatologyCredit: CC0 Public DomainNew research presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that use of warfarin, a vit

Warfarin use significantly increases risk of knee and hip replacement in people with OA

by American College of RheumatologyCredit: CC0 Public DomainNew research presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that use of warfarin, a vit