OX40-positive follicular helper T cells control rheumatoid arthritis

by University of TsukubaCredit: CC0 Public DomainRheumatoid arthritis is a progressive autoimmune disease most frequently characterized by pain, swelling, and stiffness in joints. Increased numbe

Updated on: June 17,2024

OX40-positive follicular helper T cells control rheumatoid arthritis

by University of TsukubaCredit: CC0 Public DomainRheumatoid arthritis is a progressive autoimmune disease most frequently characterized by pain, swelling, and stiffness in joints. Increased numbe

Updated on:June 17,2024

High false negative rate with PFTs in scleroderma lung disease

(HealthDay)—Use of pulmonary function tests (PFTs) is associated with high false negative rates for detection of scleroderma-associated interstitial lung disease (SSc-ILD), according to a study publis

Updated on: March 24,2024

High false negative rate with PFTs in scleroderma lung disease

(HealthDay)—Use of pulmonary function tests (PFTs) is associated with high false negative rates for detection of scleroderma-associated interstitial lung disease (SSc-ILD), according to a study publis

Updated on:March 24,2024

Scientists create first mouse model with complete, functional human immune system

byUniversity of Texas Health Science Center at San AntonioLeft, malar rash in a (huNSGW41-derived) Lupus THX mouse (three weeks after pristane injection). Middle, serum antinuclear IgGs (scale b

Updated on: July 09,2024

Scientists create first mouse model with complete, functional human immune system

byUniversity of Texas Health Science Center at San AntonioLeft, malar rash in a (huNSGW41-derived) Lupus THX mouse (three weeks after pristane injection). Middle, serum antinuclear IgGs (scale b

Updated on:July 09,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on: April 16,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on:April 16,2024

Does physical activity impact risk of knee osteoarthritis?

by WileyCredit: CC0 Public DomainIn an analysis published inArthritis & Rheumatology, investigators did not find any link between the amount and duration of physical activity with indiv

Updated on: April 17,2024

Does physical activity impact risk of knee osteoarthritis?

by WileyCredit: CC0 Public DomainIn an analysis published inArthritis & Rheumatology, investigators did not find any link between the amount and duration of physical activity with indiv

Updated on:April 17,2024

Scientists discover new mechanism controlling T-cells in inflammation

by Melissa Rohman,Northwestern UniversityGraphical abstract. Credit:Immunity(2024). DOI: 10.1016/j.immuni.2024.08.008Northwestern Medicine scientists have discovered a new mechanism

Updated on: October 10,2024

Scientists discover new mechanism controlling T-cells in inflammation

by Melissa Rohman,Northwestern UniversityGraphical abstract. Credit:Immunity(2024). DOI: 10.1016/j.immuni.2024.08.008Northwestern Medicine scientists have discovered a new mechanism

Updated on:October 10,2024

Survival improving after hip and knee replacement

(HealthDay)—Short-term survival after elective total hip (THR) and total knee replacement (TKR) has greatly improved since the early 1990s, even though comorbidities have increased, according to a stu

Updated on: April 08,2024

Survival improving after hip and knee replacement

(HealthDay)—Short-term survival after elective total hip (THR) and total knee replacement (TKR) has greatly improved since the early 1990s, even though comorbidities have increased, according to a stu

Updated on:April 08,2024

Detecting arthritis with light

by Fraunhofer-GesellschaftA finger scanner allows doctors to detect arthritis in its early stages. Credit: Fraunhofer IBMT/Bernd MüllerJoint inflammation (arthritis) is a common problem in medica

Updated on: April 07,2024

Detecting arthritis with light

by Fraunhofer-GesellschaftA finger scanner allows doctors to detect arthritis in its early stages. Credit: Fraunhofer IBMT/Bernd MüllerJoint inflammation (arthritis) is a common problem in medica

Updated on:April 07,2024

Unusual type of antibody shows ultrapotent activity against Zika

by Weill Cornell Medical CollegeZika virus particles (red) shown in African green monkey kidney cells. Credit: NIAIDAn unusual type of antibody that even at miniscule levels neutralizes the Zika

Updated on: May 07,2024

Unusual type of antibody shows ultrapotent activity against Zika

by Weill Cornell Medical CollegeZika virus particles (red) shown in African green monkey kidney cells. Credit: NIAIDAn unusual type of antibody that even at miniscule levels neutralizes the Zika

Updated on:May 07,2024

Weight loss predicts mortality in rheumatoid arthritis

(HealthDay)—Weight loss is a strong predictor of mortality in patients with rheumatoid arthritis (RA), according to a study published online June 26 inArthritis & Rheumatology.Joshua F. Bake

Updated on: April 08,2024

Weight loss predicts mortality in rheumatoid arthritis

(HealthDay)—Weight loss is a strong predictor of mortality in patients with rheumatoid arthritis (RA), according to a study published online June 26 inArthritis & Rheumatology.Joshua F. Bake

Updated on:April 08,2024

B cells linked to immunotherapy for melanoma

by European Molecular Biology LaboratoryUsing multiplex-immunostaining to characterise B cells. Credit: Christine WagnerResearchers at EMBL's European Bioinformatics Institute and the Medical

Updated on: April 08,2024

B cells linked to immunotherapy for melanoma

by European Molecular Biology LaboratoryUsing multiplex-immunostaining to characterise B cells. Credit: Christine WagnerResearchers at EMBL's European Bioinformatics Institute and the Medical

Updated on:April 08,2024

Method for delivering immune system-stimulating drugs may enhance cancer immunotherapy

by Anne Trafton,Massachusetts Institute of TechnologyThis image depicts a tumor right after treatment with alum-bound IL12. The pink dye shows IL-12, and the yellow shows alum. Credit: Massachus

Updated on: May 08,2024

Method for delivering immune system-stimulating drugs may enhance cancer immunotherapy

by Anne Trafton,Massachusetts Institute of TechnologyThis image depicts a tumor right after treatment with alum-bound IL12. The pink dye shows IL-12, and the yellow shows alum. Credit: Massachus

Updated on:May 08,2024