Could CAR-T cell therapy improve kidney transplants?

by Susan Buckles, Mayo Clinic News NetworkCredit:Kidney International(2024). DOI: 10.1016/j.kint.2024.02.008Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) could provide a re

Updated on: April 28,2024

Could CAR-T cell therapy improve kidney transplants?

by Susan Buckles, Mayo Clinic News NetworkCredit:Kidney International(2024). DOI: 10.1016/j.kint.2024.02.008Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) could provide a re

Updated on:April 28,2024

TLK protein inhibition activates the innate immune system

by Institute for Research in Biomedicine - IRBCancer cells with TLK inhibition show replication intermediates (green) at chromosome ends (red). Credit: IRB BarcelonaTousled-like kinases (TLKs) are a p

Updated on: April 24,2024

TLK protein inhibition activates the innate immune system

by Institute for Research in Biomedicine - IRBCancer cells with TLK inhibition show replication intermediates (green) at chromosome ends (red). Credit: IRB BarcelonaTousled-like kinases (TLKs) are a p

Updated on:April 24,2024

Small molecules induce trained immunity, opening a new approach to fighting disease

by Emily Ayshford,University of ChicagoMyeloid immune cells alongsidered blood cells in an electron micrograph of human blood. Credit: National Cancer InstituteVaccines provide a front-lin

Updated on: July 09,2024

Small molecules induce trained immunity, opening a new approach to fighting disease

by Emily Ayshford,University of ChicagoMyeloid immune cells alongsidered blood cells in an electron micrograph of human blood. Credit: National Cancer InstituteVaccines provide a front-lin

Updated on:July 09,2024

Study: Rheumatoid arthritis plus depression may be deadly

Risk of mood-related mortality greater for men.(HealthDay)—People with rheumatoid arthritis have higher-than-normal rates of depression, which could increase their risk of death, according to a new st

Updated on: March 24,2024

Study: Rheumatoid arthritis plus depression may be deadly

Risk of mood-related mortality greater for men.(HealthDay)—People with rheumatoid arthritis have higher-than-normal rates of depression, which could increase their risk of death, according to a new st

Updated on:March 24,2024

Air pollution linked to having a peanut allergy during childhood

byMurdoch Children's Research InstituteCredit: Pixabay/CC0 Public DomainExposure to higher levels of air pollution as a baby is linked to having a peanut allergy throughout childhood, accord

Updated on: November 01,2024

Air pollution linked to having a peanut allergy during childhood

byMurdoch Children's Research InstituteCredit: Pixabay/CC0 Public DomainExposure to higher levels of air pollution as a baby is linked to having a peanut allergy throughout childhood, accord

Updated on:November 01,2024

Macrophages produce heat from brown adipose tissue in response to cold, study reveals

by University of TsukubaGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113978Researchers from University of Tsukuba have elucidated the molecular mechanism

Updated on: March 27,2024

Macrophages produce heat from brown adipose tissue in response to cold, study reveals

by University of TsukubaGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113978Researchers from University of Tsukuba have elucidated the molecular mechanism

Updated on:March 27,2024

Antibodies against phosphorylcholine give protection against rheumatic systemic disease

by Karolinska InstitutetCredit: Pixabay/CC0 Public DomainA novel study from the Institute of Environmental Medicine at Karolinska Institutet indicates that antibodies against a small lipid entity

Updated on: May 29,2024

Antibodies against phosphorylcholine give protection against rheumatic systemic disease

by Karolinska InstitutetCredit: Pixabay/CC0 Public DomainA novel study from the Institute of Environmental Medicine at Karolinska Institutet indicates that antibodies against a small lipid entity

Updated on:May 29,2024

CVD risk factors tied to disease activity, disability in RA

(HealthDay)—Cardiovascular disease (CVD) risk factors alone, or in combination, are associated with higher disease activity and disability in rheumatoid arthritis (RA), according to a study recently p

Updated on: June 01,2024

CVD risk factors tied to disease activity, disability in RA

(HealthDay)—Cardiovascular disease (CVD) risk factors alone, or in combination, are associated with higher disease activity and disability in rheumatoid arthritis (RA), according to a study recently p

Updated on:June 01,2024

How IL-33 plays a key role in enabling the marathon runners of the immune system

by University of BaselGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.01.029When it comes to chronic infections and cancer, a particular type of immune cell play

Updated on: April 16,2024

How IL-33 plays a key role in enabling the marathon runners of the immune system

by University of BaselGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.01.029When it comes to chronic infections and cancer, a particular type of immune cell play

Updated on:April 16,2024

Novel checkpoint molecule of natural killer cell anti-tumor immunity revealed

by Li Yuan,Chinese Academy of SciencesFig. 1. TIPE2 expression correlates with NK cell maturation in both mice and humans.(A) TIPE2 expression of purified splenic NK cells from 2-, 4-, 6-, or 10

Updated on: April 20,2024

Novel checkpoint molecule of natural killer cell anti-tumor immunity revealed

by Li Yuan,Chinese Academy of SciencesFig. 1. TIPE2 expression correlates with NK cell maturation in both mice and humans.(A) TIPE2 expression of purified splenic NK cells from 2-, 4-, 6-, or 10

Updated on:April 20,2024

Low back pain? Don't blame the weather

by WileyCloud in Nepali sky. Credit: WikipediaAustralian researchers reveal that sudden, acute episodes of low back pain are not linked to weather conditions such as temperature, humidity, air pr

Updated on: March 24,2024

Low back pain? Don't blame the weather

by WileyCloud in Nepali sky. Credit: WikipediaAustralian researchers reveal that sudden, acute episodes of low back pain are not linked to weather conditions such as temperature, humidity, air pr

Updated on:March 24,2024

Expensive arthritis treatment no better than steroid therapy

by Hospital for Special Surgery“On average, each of the therapies resulted in clinically meaningful improvement in pain,” said Lisa Mandl, M.D., MPH, a rheumatologist at Hospital for Special Surg

Updated on: March 24,2024

Expensive arthritis treatment no better than steroid therapy

by Hospital for Special Surgery“On average, each of the therapies resulted in clinically meaningful improvement in pain,” said Lisa Mandl, M.D., MPH, a rheumatologist at Hospital for Special Surg

Updated on:March 24,2024