Here's why B cells benefit from booster shots

byRockefeller UniversityRecall germinal centers formed in response to a secondary infection generate a second line of defense, rebuffing memory B cells in favor of training naive ones. Credit: R

Updated on: October 10,2024 0

Here's why B cells benefit from booster shots

byRockefeller UniversityRecall germinal centers formed in response to a secondary infection generate a second line of defense, rebuffing memory B cells in favor of training naive ones. Credit: R

Updated on:October 10,2024 0

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on: April 16,2024 11

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on:April 16,2024 11

The case of the missing monocyte: Scientists investigate gene that appears to protect against rheumatoid arthritis

by University of North Carolina at Chapel Hill School of MedicineThe hands of a person with arthritis. Image source: NIH.(Medical Xpress) -- An estimated 1.3 million people in the United States s

Updated on: March 24,2024 16

The case of the missing monocyte: Scientists investigate gene that appears to protect against rheumatoid arthritis

by University of North Carolina at Chapel Hill School of MedicineThe hands of a person with arthritis. Image source: NIH.(Medical Xpress) -- An estimated 1.3 million people in the United States s

Updated on:March 24,2024 16

Old immune systems revitalized in mouse study, may improve vaccine response in the elderly

byStanford University Medical CenterCredit: CC0 Public DomainPlanes, trains, boats, automobiles and even feet. During the past decades and centuries, global travel and human migration have made

Updated on: March 30,2024 6

Old immune systems revitalized in mouse study, may improve vaccine response in the elderly

byStanford University Medical CenterCredit: CC0 Public DomainPlanes, trains, boats, automobiles and even feet. During the past decades and centuries, global travel and human migration have made

Updated on:March 30,2024 6

Study of infants and young children shows that offspring develop normally in mothers with rheumatic disease

by European League Against Rheumatism (EULAR)Credit: CC0 Public DomainAnkylosing spondylitis (AS) is a complex chronic inflammatory disease of the spine with involvement of the sacroiliac joints. Over

Updated on: June 26,2024 4

Study of infants and young children shows that offspring develop normally in mothers with rheumatic disease

by European League Against Rheumatism (EULAR)Credit: CC0 Public DomainAnkylosing spondylitis (AS) is a complex chronic inflammatory disease of the spine with involvement of the sacroiliac joints. Over

Updated on:June 26,2024 4

Proteinuria level predicts renal outcome in lupus nephritis

(HealthDay)—Proteinuria levels at 12 months are the best predictor of long-term renal outcome in patients with lupus nephritis, according to a study published in the May issue ofArthritis &

Updated on: March 24,2024 20

Proteinuria level predicts renal outcome in lupus nephritis

(HealthDay)—Proteinuria levels at 12 months are the best predictor of long-term renal outcome in patients with lupus nephritis, according to a study published in the May issue ofArthritis &

Updated on:March 24,2024 20

A tiny molecule with a big impact

by Otto-von-Guericke-Universität MagdeburgProf. Dr. Andreas J. Müller, Head of the Intravital Microscopy of Infection and Immunity Group, Institute of Molecular and Clinical Immunology, Faculty of Med

Updated on: May 05,2024 13

A tiny molecule with a big impact

by Otto-von-Guericke-Universität MagdeburgProf. Dr. Andreas J. Müller, Head of the Intravital Microscopy of Infection and Immunity Group, Institute of Molecular and Clinical Immunology, Faculty of Med

Updated on:May 05,2024 13

VAV1 gene mutations trigger T-cell tumors in mice

by University of TsukubaCredit: CC0 Public DomainLife is an exquisite orchestration of growth and change, with checks and balances that fine-tune complex entwined interactions, both intrinsic and

Updated on: May 06,2024 13

VAV1 gene mutations trigger T-cell tumors in mice

by University of TsukubaCredit: CC0 Public DomainLife is an exquisite orchestration of growth and change, with checks and balances that fine-tune complex entwined interactions, both intrinsic and

Updated on:May 06,2024 13

PFAS can suppress white blood cell's ability to destroy invaders

by Tracey Peake,North Carolina State UniversityPFASs used in this study. Names and structures of the PFASs used in this study. Vendors and CAS-RN numbers are provided in Table 1. Chemical struct

Updated on: April 20,2024 17

PFAS can suppress white blood cell's ability to destroy invaders

by Tracey Peake,North Carolina State UniversityPFASs used in this study. Names and structures of the PFASs used in this study. Vendors and CAS-RN numbers are provided in Table 1. Chemical struct

Updated on:April 20,2024 17

Expensive arthritis treatment no better than steroid therapy

by Hospital for Special Surgery“On average, each of the therapies resulted in clinically meaningful improvement in pain,” said Lisa Mandl, M.D., MPH, a rheumatologist at Hospital for Special Surg

Updated on: March 24,2024 10

Expensive arthritis treatment no better than steroid therapy

by Hospital for Special Surgery“On average, each of the therapies resulted in clinically meaningful improvement in pain,” said Lisa Mandl, M.D., MPH, a rheumatologist at Hospital for Special Surg

Updated on:March 24,2024 10

Inflammatory link discovered between arthritis and heart valve disease

by Walter and Eliza Hall InstituteAustralian researchers have used models to identify a potential link between excess production of inflammatory proteins that cause rheumatoid arthritis and the d

Updated on: March 24,2024 14

Inflammatory link discovered between arthritis and heart valve disease

by Walter and Eliza Hall InstituteAustralian researchers have used models to identify a potential link between excess production of inflammatory proteins that cause rheumatoid arthritis and the d

Updated on:March 24,2024 14

Anti-cancer virus fits tumor receptor like a 'key in a lock'

by Okinawa Institute of Science and TechnologyA cryo-EM map of the receptor decorated capsid in which a single protomer was replaced with the atomic model. Seneca Valley Virus capsid proteins are

Updated on: April 08,2024 18

Anti-cancer virus fits tumor receptor like a 'key in a lock'

by Okinawa Institute of Science and TechnologyA cryo-EM map of the receptor decorated capsid in which a single protomer was replaced with the atomic model. Seneca Valley Virus capsid proteins are

Updated on:April 08,2024 18