Small molecules induce trained immunity, opening a new approach to fighting disease

by Emily Ayshford,University of ChicagoMyeloid immune cells alongsidered blood cells in an electron micrograph of human blood. Credit: National Cancer InstituteVaccines provide a front-lin

Updated on: July 09,2024

Small molecules induce trained immunity, opening a new approach to fighting disease

by Emily Ayshford,University of ChicagoMyeloid immune cells alongsidered blood cells in an electron micrograph of human blood. Credit: National Cancer InstituteVaccines provide a front-lin

Updated on:July 09,2024

New study questions the efficacy of many osteoarthritis treatments

by Lund UniversityCredit: Pixabay/CC0 Public DomainRecruiting osteoarthritis patients with a lot of pain to clinical studies may give incorrect results if the researcher does not account for the

Updated on: May 26,2024

New study questions the efficacy of many osteoarthritis treatments

by Lund UniversityCredit: Pixabay/CC0 Public DomainRecruiting osteoarthritis patients with a lot of pain to clinical studies may give incorrect results if the researcher does not account for the

Updated on:May 26,2024

Rheumatoid arthritis drug not linked to specific birth defects

The rheumatoid arthritis drug leflunomide is not a major cause of birth defects in women who inadvertently become pregnant while taking the drug, although pregnancy should be avoided, according to a s

Updated on: March 24,2024

Rheumatoid arthritis drug not linked to specific birth defects

The rheumatoid arthritis drug leflunomide is not a major cause of birth defects in women who inadvertently become pregnant while taking the drug, although pregnancy should be avoided, according to a s

Updated on:March 24,2024

Methotrexate improves function in people with knee OA after three months

by American College of RheumatologyCredit: CC0 Public DomainA new study presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that after three months of t

Updated on: May 13,2024

Methotrexate improves function in people with knee OA after three months

by American College of RheumatologyCredit: CC0 Public DomainA new study presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that after three months of t

Updated on:May 13,2024

Why inflammatory arthritis always recurs in certain joints

by Children's Hospital BostonCredit: Unsplash/CC0 Public DomainWhen joints flare up in people with rheumatoid arthritis and related diseases, the joints involved are often the same as those a

Updated on: June 17,2024

Why inflammatory arthritis always recurs in certain joints

by Children's Hospital BostonCredit: Unsplash/CC0 Public DomainWhen joints flare up in people with rheumatoid arthritis and related diseases, the joints involved are often the same as those a

Updated on:June 17,2024

Arthritis reported by almost one in four U.S. adults

(HealthDay)—Almost one-quarter of U.S. adults report arthritis, according to research published in the Oct. 8 issue of the U.S. Centers for Disease Control and PreventionMorbidity and Mortality

Updated on: May 08,2024

Arthritis reported by almost one in four U.S. adults

(HealthDay)—Almost one-quarter of U.S. adults report arthritis, according to research published in the Oct. 8 issue of the U.S. Centers for Disease Control and PreventionMorbidity and Mortality

Updated on:May 08,2024

MyD88—villain of allergies and asthma

by Lydia Goff ,Duke UniversityFlorescence microscopy image of mouse dendritic cells with mRNA-loaded blood cells.Even if you don't have allergies yourself, I guarantee you can list at

Updated on: April 20,2024

MyD88—villain of allergies and asthma

by Lydia Goff ,Duke UniversityFlorescence microscopy image of mouse dendritic cells with mRNA-loaded blood cells.Even if you don't have allergies yourself, I guarantee you can list at

Updated on:April 20,2024

Proportion of adults diagnosed with inflammatory arthritis in England has increased by more than 40%

by Keele UniversityPercentage of patients with at least 1 Read/SNOMED code for RA who meet the diagnosis algorithm. Panel A = percentage of patients ever receiving an RA Read/SNOMED code that mee

Updated on: March 28,2024

Proportion of adults diagnosed with inflammatory arthritis in England has increased by more than 40%

by Keele UniversityPercentage of patients with at least 1 Read/SNOMED code for RA who meet the diagnosis algorithm. Panel A = percentage of patients ever receiving an RA Read/SNOMED code that mee

Updated on:March 28,2024

Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to

Updated on: September 07,2024

Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to

Updated on:September 07,2024

TLK protein inhibition activates the innate immune system

by Institute for Research in Biomedicine - IRBCancer cells with TLK inhibition show replication intermediates (green) at chromosome ends (red). Credit: IRB BarcelonaTousled-like kinases (TLKs) are a p

Updated on: April 24,2024

TLK protein inhibition activates the innate immune system

by Institute for Research in Biomedicine - IRBCancer cells with TLK inhibition show replication intermediates (green) at chromosome ends (red). Credit: IRB BarcelonaTousled-like kinases (TLKs) are a p

Updated on:April 24,2024

How IL-33 plays a key role in enabling the marathon runners of the immune system

by University of BaselGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.01.029When it comes to chronic infections and cancer, a particular type of immune cell play

Updated on: April 16,2024

How IL-33 plays a key role in enabling the marathon runners of the immune system

by University of BaselGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.01.029When it comes to chronic infections and cancer, a particular type of immune cell play

Updated on:April 16,2024

NSAIDs may worsen arthritis inflammation

by Radiological Society of North AmericaThe fat pad adjacent to the kneecap (Hoffa's fat pad, infrapatellar fat pad) can change in signal on MRI when the knee is inflamed. (A) Normal knee wit

Updated on: June 26,2024

NSAIDs may worsen arthritis inflammation

by Radiological Society of North AmericaThe fat pad adjacent to the kneecap (Hoffa's fat pad, infrapatellar fat pad) can change in signal on MRI when the knee is inflamed. (A) Normal knee wit

Updated on:June 26,2024