TLK protein inhibition activates the innate immune system

by Institute for Research in Biomedicine - IRBCancer cells with TLK inhibition show replication intermediates (green) at chromosome ends (red). Credit: IRB BarcelonaTousled-like kinases (TLKs) are a p

Updated on: April 24,2024

TLK protein inhibition activates the innate immune system

by Institute for Research in Biomedicine - IRBCancer cells with TLK inhibition show replication intermediates (green) at chromosome ends (red). Credit: IRB BarcelonaTousled-like kinases (TLKs) are a p

Updated on:April 24,2024

Upadacitinib beats placebo for psoriatic arthritis

For patients with psoriatic arthritis, upadacitinib at a dose of 15 mg or 30 mg once daily is more effective than placebo, according to a study published in the April 1 issue of theNew England J

Updated on: May 26,2024

Upadacitinib beats placebo for psoriatic arthritis

For patients with psoriatic arthritis, upadacitinib at a dose of 15 mg or 30 mg once daily is more effective than placebo, according to a study published in the April 1 issue of theNew England J

Updated on:May 26,2024

Prevalence of multimorbidity up in rheumatoid arthritis

Patients with rheumatoid arthritis (RA) have an increased prevalence of multimorbidity, according to a study recently published inRMD Open.Cynthia S. Crowson, Ph.D., from the Mayo Clinic in Roch

Updated on: June 17,2024

Prevalence of multimorbidity up in rheumatoid arthritis

Patients with rheumatoid arthritis (RA) have an increased prevalence of multimorbidity, according to a study recently published inRMD Open.Cynthia S. Crowson, Ph.D., from the Mayo Clinic in Roch

Updated on:June 17,2024

In veterans with RA, PTSD worsens disease activity

For U.S. veterans with rheumatoid arthritis, a diagnosis of posttraumatic stress disorder is associated with worse patient-reported outcomes and tender joint counts, according to a study published onl

Updated on: March 30,2024

In veterans with RA, PTSD worsens disease activity

For U.S. veterans with rheumatoid arthritis, a diagnosis of posttraumatic stress disorder is associated with worse patient-reported outcomes and tender joint counts, according to a study published onl

Updated on:March 30,2024

Program may help patients with rheumatic diseases quit smoking

by WileyCredit: CC0 Public DomainSmoking increases symptoms and health risks for patients with rheumatic diseases, but interventions to help patients quit are rarely available at rheumatology cli

Updated on: March 28,2024

Program may help patients with rheumatic diseases quit smoking

by WileyCredit: CC0 Public DomainSmoking increases symptoms and health risks for patients with rheumatic diseases, but interventions to help patients quit are rarely available at rheumatology cli

Updated on:March 28,2024

A new, potent weapon against lymphomas

by Max Delbrück Center for Molecular MedicineAnti-CXCR5 CAR-T cells (green) attack lymphoma cells (magenta) within the stroma cell network of the B cell follicle (light blue). Credit: AG Höpken /

Updated on: May 05,2024

A new, potent weapon against lymphomas

by Max Delbrück Center for Molecular MedicineAnti-CXCR5 CAR-T cells (green) attack lymphoma cells (magenta) within the stroma cell network of the B cell follicle (light blue). Credit: AG Höpken /

Updated on:May 05,2024

Five genes tied to osteoarthritis progression

(HealthDay)—Five genes may serve as biomarkers for osteoarthritis (OA) progression, according to a study published online Feb. 2 in theInternational Journal of Rheumatic Diseases.Beiyue Wang, fr

Updated on: April 07,2024

Five genes tied to osteoarthritis progression

(HealthDay)—Five genes may serve as biomarkers for osteoarthritis (OA) progression, according to a study published online Feb. 2 in theInternational Journal of Rheumatic Diseases.Beiyue Wang, fr

Updated on:April 07,2024

Epigenetics alters genes in rheumatoid arthritis

by University of California - San DiegoIn this artist's rendering, a DNA molecule is methylated on both strands at the center cytosine. DNA methylation plays an important role in epigenetic g

Updated on: March 24,2024

Epigenetics alters genes in rheumatoid arthritis

by University of California - San DiegoIn this artist's rendering, a DNA molecule is methylated on both strands at the center cytosine. DNA methylation plays an important role in epigenetic g

Updated on:March 24,2024

Adults with psoriasis more likely to have rheumatoid arthritis

(HealthDay)—Adults with psoriasis have an increased likelihood of having rheumatoid arthritis (RA) compared with adults without psoriasis, according to a study published online June 15 in theJou

Updated on: May 08,2024

Adults with psoriasis more likely to have rheumatoid arthritis

(HealthDay)—Adults with psoriasis have an increased likelihood of having rheumatoid arthritis (RA) compared with adults without psoriasis, according to a study published online June 15 in theJou

Updated on:May 08,2024

Study: Rheumatoid arthritis plus depression may be deadly

Risk of mood-related mortality greater for men.(HealthDay)—People with rheumatoid arthritis have higher-than-normal rates of depression, which could increase their risk of death, according to a new st

Updated on: March 24,2024

Study: Rheumatoid arthritis plus depression may be deadly

Risk of mood-related mortality greater for men.(HealthDay)—People with rheumatoid arthritis have higher-than-normal rates of depression, which could increase their risk of death, according to a new st

Updated on:March 24,2024

Expensive arthritis treatment no better than steroid therapy

by Hospital for Special Surgery“On average, each of the therapies resulted in clinically meaningful improvement in pain,” said Lisa Mandl, M.D., MPH, a rheumatologist at Hospital for Special Surg

Updated on: March 24,2024

Expensive arthritis treatment no better than steroid therapy

by Hospital for Special Surgery“On average, each of the therapies resulted in clinically meaningful improvement in pain,” said Lisa Mandl, M.D., MPH, a rheumatologist at Hospital for Special Surg

Updated on:March 24,2024

Aerobic exercise may cut fatigue in rheumatoid arthritis

(HealthDay)—Aerobic land-based exercise may be helpful in treating fatigue in patients with rheumatoid arthritis (RA), according to a meta-analysis published in the August issue ofArthritis Care

Updated on: March 24,2024

Aerobic exercise may cut fatigue in rheumatoid arthritis

(HealthDay)—Aerobic land-based exercise may be helpful in treating fatigue in patients with rheumatoid arthritis (RA), according to a meta-analysis published in the August issue ofArthritis Care

Updated on:March 24,2024