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Immunology & Rheumatology
Focuses on rheumatic and immune diseases.
Sub Categories on Immunology & Rheumatology
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HSPC-derived CAR T-cells capable of lasting engraftment

HSPC-derived CAR T-cells capable of lasting engraftment

(HealthDay)—Hematopoietic stem/progenitor cell (HSPC)-derived chimeric antigen receptor (CAR) T-cells are capable of long-term engraftment in a model of HIV/AIDS, according to a study published online

HSPC-derived CAR T-cells capable of lasting engraftment

(HealthDay)—Hematopoietic stem/progenitor cell (HSPC)-derived chimeric antigen receptor (CAR) T-cells are capable of long-term engraftment in a model of HIV/AIDS, according to a study published online
NSAIDs may worsen arthritis inflammation

NSAIDs may worsen arthritis inflammation

by Radiological Society of North AmericaThe fat pad adjacent to the kneecap (Hoffa's fat pad, infrapatellar fat pad) can change in signal on MRI when the knee is inflamed. (A) Normal knee wit

NSAIDs may worsen arthritis inflammation

by Radiological Society of North AmericaThe fat pad adjacent to the kneecap (Hoffa's fat pad, infrapatellar fat pad) can change in signal on MRI when the knee is inflamed. (A) Normal knee wit
Risankizumab safe, effective at 52 weeks for psoriatic arthritis

Risankizumab safe, effective at 52 weeks for psoriatic arthritis

by Lori SolomonRisankizumab provides long-term benefits in patients with psoriatic arthritis (PsA) who have not achieved adequate response to previous therapies, according to a study recently publishe

Risankizumab safe, effective at 52 weeks for psoriatic arthritis

by Lori SolomonRisankizumab provides long-term benefits in patients with psoriatic arthritis (PsA) who have not achieved adequate response to previous therapies, according to a study recently publishe
A protein that controls inflammation

A protein that controls inflammation

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainA study by the research team of Prof. Geert van Loo (VIB-UGent Center for Inflammation Research) has unraveled a critical

A protein that controls inflammation

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainA study by the research team of Prof. Geert van Loo (VIB-UGent Center for Inflammation Research) has unraveled a critical
How a COVID-19 infection spurs antibodies against common colds

How a COVID-19 infection spurs antibodies against common colds

by The Scripps Research InstituteResearchers analyzed the structures of antibodies (colored) from healthy donors as the molecules bound to the spike protein from common coronaviruses like OC43 (s

How a COVID-19 infection spurs antibodies against common colds

by The Scripps Research InstituteResearchers analyzed the structures of antibodies (colored) from healthy donors as the molecules bound to the spike protein from common coronaviruses like OC43 (s
High false negative rate with PFTs in scleroderma lung disease

High false negative rate with PFTs in scleroderma lung disease

(HealthDay)—Use of pulmonary function tests (PFTs) is associated with high false negative rates for detection of scleroderma-associated interstitial lung disease (SSc-ILD), according to a study publis

High false negative rate with PFTs in scleroderma lung disease

(HealthDay)—Use of pulmonary function tests (PFTs) is associated with high false negative rates for detection of scleroderma-associated interstitial lung disease (SSc-ILD), according to a study publis
The secret lives of T cells: They derive energy from a master regulator that has been poorly understood, until now

The secret lives of T cells: They derive energy from a master regulator that has been poorly understood, until now

by Delthia Ricks , Medical XpressIn vitro modeling of Teff STAT5 responses. (A) WT CD4+ T cells were cultured with or without blocking anti-mouse IL-2/IL-2R antibodies and/or human IL-2. Flow cytometr

The secret lives of T cells: They derive energy from a master regulator that has been poorly understood, until now

by Delthia Ricks , Medical XpressIn vitro modeling of Teff STAT5 responses. (A) WT CD4+ T cells were cultured with or without blocking anti-mouse IL-2/IL-2R antibodies and/or human IL-2. Flow cytometr
Compound found to trigger innate immunity against viruses

Compound found to trigger innate immunity against viruses

by Bobbi Nodell,University of WashingtonCells under a microscope in a UW Medicine immunity lab. Credit: Dennis WiseResearch from UW Medicine and collaborators indicates that a drug-like molecule

Compound found to trigger innate immunity against viruses

by Bobbi Nodell,University of WashingtonCells under a microscope in a UW Medicine immunity lab. Credit: Dennis WiseResearch from UW Medicine and collaborators indicates that a drug-like molecule
Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

by Bob Yirka , Medical XpressPerturbation of X-inactivation in immune cells ofFtx−/−females.(A) Map of the X inactivation center showing the location ofXist(green) andFtx

Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

by Bob Yirka , Medical XpressPerturbation of X-inactivation in immune cells ofFtx−/−females.(A) Map of the X inactivation center showing the location ofXist(green) andFtx
Identification of LZTR1 leads to novel insights into RAS-driven diseases

Identification of LZTR1 leads to novel insights into RAS-driven diseases

by VIB (the Flanders Institute for Biotechnology)Cancer cell during cell division. Credit: National Institutes of HealthMutations in RAS proteins initiate many of the most aggressive tumors, and

Identification of LZTR1 leads to novel insights into RAS-driven diseases

by VIB (the Flanders Institute for Biotechnology)Cancer cell during cell division. Credit: National Institutes of HealthMutations in RAS proteins initiate many of the most aggressive tumors, and
Knee pain not linked with activity levels in adults with knee osteoarthritis

Knee pain not linked with activity levels in adults with knee osteoarthritis

by WileyCredit: CC0 Public DomainKnee pain was not associated with daily walking levels in anArthritis Care & Researchstudy of individuals with mild-to-moderate, symptomatic knee

Knee pain not linked with activity levels in adults with knee osteoarthritis

by WileyCredit: CC0 Public DomainKnee pain was not associated with daily walking levels in anArthritis Care & Researchstudy of individuals with mild-to-moderate, symptomatic knee
Major savings possible with app-based osteoarthritis treatment

Major savings possible with app-based osteoarthritis treatment

by Lund UniversityCredit: CC0 Public DomainOsteoarthritis treatment conducted digitally via an app costs around 25% of what conventional care costs, according to a study from Lund University in S

Major savings possible with app-based osteoarthritis treatment

by Lund UniversityCredit: CC0 Public DomainOsteoarthritis treatment conducted digitally via an app costs around 25% of what conventional care costs, according to a study from Lund University in S