Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to

Updated on: September 07,2024

Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to

Updated on:September 07,2024

Patient-Rated elbow evaluation most responsive instrument

The Patient-Rated Elbow Evaluation form is the most responsive instrument to identify and quantify elbow joint-specific changes before and after total elbow arthroplasty, according to a study publishe

Updated on: April 08,2024

Patient-Rated elbow evaluation most responsive instrument

The Patient-Rated Elbow Evaluation form is the most responsive instrument to identify and quantify elbow joint-specific changes before and after total elbow arthroplasty, according to a study publishe

Updated on:April 08,2024

TLK protein inhibition activates the innate immune system

by Institute for Research in Biomedicine - IRBCancer cells with TLK inhibition show replication intermediates (green) at chromosome ends (red). Credit: IRB BarcelonaTousled-like kinases (TLKs) are a p

Updated on: April 24,2024

TLK protein inhibition activates the innate immune system

by Institute for Research in Biomedicine - IRBCancer cells with TLK inhibition show replication intermediates (green) at chromosome ends (red). Credit: IRB BarcelonaTousled-like kinases (TLKs) are a p

Updated on:April 24,2024

CAR T cells suppress GI solid tumor cells, without toxicity to healthy tissue, in preclinical research

by University of PennsylvaniaCDH17 CARTs attack tumor but spare normal tissue. Credit: Penn MedicineChimeric antigen receptor (CAR) T cells can be remarkably effective in treating leukemias and l

Updated on: April 09,2024

CAR T cells suppress GI solid tumor cells, without toxicity to healthy tissue, in preclinical research

by University of PennsylvaniaCDH17 CARTs attack tumor but spare normal tissue. Credit: Penn MedicineChimeric antigen receptor (CAR) T cells can be remarkably effective in treating leukemias and l

Updated on:April 09,2024

Antibodies against phosphorylcholine give protection against rheumatic systemic disease

by Karolinska InstitutetCredit: Pixabay/CC0 Public DomainA novel study from the Institute of Environmental Medicine at Karolinska Institutet indicates that antibodies against a small lipid entity

Updated on: May 29,2024

Antibodies against phosphorylcholine give protection against rheumatic systemic disease

by Karolinska InstitutetCredit: Pixabay/CC0 Public DomainA novel study from the Institute of Environmental Medicine at Karolinska Institutet indicates that antibodies against a small lipid entity

Updated on:May 29,2024

Does body mass index impact pain in individuals with hand osteoarthritis?

by WileyCredit: Unsplash/CC0 Public DomainIn a study inArthritis & Rheumatologyof people with hand osteoarthritis, higher body mass index was associated with greater pain severity

Updated on: June 15,2024

Does body mass index impact pain in individuals with hand osteoarthritis?

by WileyCredit: Unsplash/CC0 Public DomainIn a study inArthritis & Rheumatologyof people with hand osteoarthritis, higher body mass index was associated with greater pain severity

Updated on:June 15,2024

Five genes tied to osteoarthritis progression

(HealthDay)—Five genes may serve as biomarkers for osteoarthritis (OA) progression, according to a study published online Feb. 2 in theInternational Journal of Rheumatic Diseases.Beiyue Wang, fr

Updated on: April 07,2024

Five genes tied to osteoarthritis progression

(HealthDay)—Five genes may serve as biomarkers for osteoarthritis (OA) progression, according to a study published online Feb. 2 in theInternational Journal of Rheumatic Diseases.Beiyue Wang, fr

Updated on:April 07,2024

A new, potent weapon against lymphomas

by Max Delbrück Center for Molecular MedicineAnti-CXCR5 CAR-T cells (green) attack lymphoma cells (magenta) within the stroma cell network of the B cell follicle (light blue). Credit: AG Höpken /

Updated on: May 05,2024

A new, potent weapon against lymphomas

by Max Delbrück Center for Molecular MedicineAnti-CXCR5 CAR-T cells (green) attack lymphoma cells (magenta) within the stroma cell network of the B cell follicle (light blue). Credit: AG Höpken /

Updated on:May 05,2024

COVID-19 model reveals key role for innate immunity in controlling viral load

by American Chemical SocietyColorized scanning electron micrograph of a cell (blue) heavily infected with SARS-CoV-2 virus particles (red), isolated from a patient sample. Image captured at the N

Updated on: April 10,2024

COVID-19 model reveals key role for innate immunity in controlling viral load

by American Chemical SocietyColorized scanning electron micrograph of a cell (blue) heavily infected with SARS-CoV-2 virus particles (red), isolated from a patient sample. Image captured at the N

Updated on:April 10,2024

Specialist nurses as good as doctors in managing rheumatoid arthritis patients

by University of LeedsPatients attending clinical nurse specialist clinics do not get inferior treatment to that offered by consultant rheumatologists, the results of a major new clinical trial h

Updated on: March 24,2024

Specialist nurses as good as doctors in managing rheumatoid arthritis patients

by University of LeedsPatients attending clinical nurse specialist clinics do not get inferior treatment to that offered by consultant rheumatologists, the results of a major new clinical trial h

Updated on:March 24,2024

Small molecules induce trained immunity, opening a new approach to fighting disease

by Emily Ayshford,University of ChicagoMyeloid immune cells alongsidered blood cells in an electron micrograph of human blood. Credit: National Cancer InstituteVaccines provide a front-lin

Updated on: July 09,2024

Small molecules induce trained immunity, opening a new approach to fighting disease

by Emily Ayshford,University of ChicagoMyeloid immune cells alongsidered blood cells in an electron micrograph of human blood. Credit: National Cancer InstituteVaccines provide a front-lin

Updated on:July 09,2024

App to monitor rheumatoid arthritis symptoms does not improve disease outcomes

(HealthDay)—Use of a smartphone application (app) to monitor patient-reported outcomes does not improve satisfaction or disease outcomes in rheumatoid arthritis (RA), but patients are likely to recomm

Updated on: May 29,2024

App to monitor rheumatoid arthritis symptoms does not improve disease outcomes

(HealthDay)—Use of a smartphone application (app) to monitor patient-reported outcomes does not improve satisfaction or disease outcomes in rheumatoid arthritis (RA), but patients are likely to recomm

Updated on:May 29,2024