Epigenetics alters genes in rheumatoid arthritis

by University of California - San DiegoIn this artist's rendering, a DNA molecule is methylated on both strands at the center cytosine. DNA methylation plays an important role in epigenetic g

Updated on: March 24,2024

Epigenetics alters genes in rheumatoid arthritis

by University of California - San DiegoIn this artist's rendering, a DNA molecule is methylated on both strands at the center cytosine. DNA methylation plays an important role in epigenetic g

Updated on:March 24,2024

A leap forward in research on CAR T cell therapy

by University of HelsinkiCredit: CC0 Public DomainIn cancer immunotherapy, cells in the patient's own immune system are activated to attack cancer cells. CAR T cell therapy has been one of th

Updated on: April 09,2024

A leap forward in research on CAR T cell therapy

by University of HelsinkiCredit: CC0 Public DomainIn cancer immunotherapy, cells in the patient's own immune system are activated to attack cancer cells. CAR T cell therapy has been one of th

Updated on:April 09,2024

Uranium exposure tied to lupus

(HealthDay)—High uranium exposure is associated with systemic lupus erythematosus (SLE), according to a study published online Aug. 7 inArthritis & Rheumatology.Pai-Yue Lu-Fritts, M.D., from

Updated on: March 24,2024

Uranium exposure tied to lupus

(HealthDay)—High uranium exposure is associated with systemic lupus erythematosus (SLE), according to a study published online Aug. 7 inArthritis & Rheumatology.Pai-Yue Lu-Fritts, M.D., from

Updated on:March 24,2024

Balance between sleep and exercise may be key to help osteoarthritis patients manage pain

by University of MichiganCredit: CC0 Public DomainIt may shoot through the hands while typing or flare in the knees when getting out of the car. Wherever the pain, over 32 million Americans livin

Updated on: May 08,2024

Balance between sleep and exercise may be key to help osteoarthritis patients manage pain

by University of MichiganCredit: CC0 Public DomainIt may shoot through the hands while typing or flare in the knees when getting out of the car. Wherever the pain, over 32 million Americans livin

Updated on:May 08,2024

Long-term rituximab safe for patients with wegener's

Repeated and prolonged use of rituximab for B-cell depletion to treat relapses or maintain remission is safe and effective in patients with refractory granulomatosis with polyangiitis (GPA; Wegener&#3

Updated on: March 28,2024

Long-term rituximab safe for patients with wegener's

Repeated and prolonged use of rituximab for B-cell depletion to treat relapses or maintain remission is safe and effective in patients with refractory granulomatosis with polyangiitis (GPA; Wegener&#3

Updated on:March 28,2024

Patient-Rated elbow evaluation most responsive instrument

The Patient-Rated Elbow Evaluation form is the most responsive instrument to identify and quantify elbow joint-specific changes before and after total elbow arthroplasty, according to a study publishe

Updated on: April 08,2024

Patient-Rated elbow evaluation most responsive instrument

The Patient-Rated Elbow Evaluation form is the most responsive instrument to identify and quantify elbow joint-specific changes before and after total elbow arthroplasty, according to a study publishe

Updated on:April 08,2024

A common metabolite may help treat autoimmune diseases

by Hokkaido UniversityIn mice models with adoptive transfer experimental autoimmune encephalomyelitis, treatment with itaconate (right) greatly ameliorates the effects of the disease, compared to

Updated on: May 08,2024

A common metabolite may help treat autoimmune diseases

by Hokkaido UniversityIn mice models with adoptive transfer experimental autoimmune encephalomyelitis, treatment with itaconate (right) greatly ameliorates the effects of the disease, compared to

Updated on:May 08,2024

GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite

Updated on: April 08,2024

GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite

Updated on:April 08,2024

A little radiation goes a long way in heating up cold tumors

by Ludwig Cancer ResearchCredit: CC0 Public DomainA Ludwig Cancer Research study conducted in both mice and a small group of patients with advanced cancers has shown that so-called "cold&quo

Updated on: April 24,2024

A little radiation goes a long way in heating up cold tumors

by Ludwig Cancer ResearchCredit: CC0 Public DomainA Ludwig Cancer Research study conducted in both mice and a small group of patients with advanced cancers has shown that so-called "cold&quo

Updated on:April 24,2024

Researchers develop a handheld white blood cell tracker

by Kitta MacPherson,Rutgers UniversityStudy overview. (A) Image of CytoTracker device prototype. (B) An image of the CytoTracker microfluidic impedance cytometer. (C) Schematic of sensing mechan

Updated on: March 07,2024

Researchers develop a handheld white blood cell tracker

by Kitta MacPherson,Rutgers UniversityStudy overview. (A) Image of CytoTracker device prototype. (B) An image of the CytoTracker microfluidic impedance cytometer. (C) Schematic of sensing mechan

Updated on:March 07,2024

NSAIDs may worsen arthritis inflammation

by Radiological Society of North AmericaThe fat pad adjacent to the kneecap (Hoffa's fat pad, infrapatellar fat pad) can change in signal on MRI when the knee is inflamed. (A) Normal knee wit

Updated on: June 26,2024

NSAIDs may worsen arthritis inflammation

by Radiological Society of North AmericaThe fat pad adjacent to the kneecap (Hoffa's fat pad, infrapatellar fat pad) can change in signal on MRI when the knee is inflamed. (A) Normal knee wit

Updated on:June 26,2024

New class of molecules play key role in influencing the immune system

by Brigham and Women's HospitalProresolving lipid mediators – resolvin D1 (RvD1), resolvin D2 (RvD2), and maresin 1 (MaR1) – modulate T cell responses. Credit: Valerio Chiurchiu et al., Scien

Updated on: May 05,2024

New class of molecules play key role in influencing the immune system

by Brigham and Women's HospitalProresolving lipid mediators – resolvin D1 (RvD1), resolvin D2 (RvD2), and maresin 1 (MaR1) – modulate T cell responses. Credit: Valerio Chiurchiu et al., Scien

Updated on:May 05,2024