GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite

Updated on: April 08,2024

GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite

Updated on:April 08,2024

A little radiation goes a long way in heating up cold tumors

by Ludwig Cancer ResearchCredit: CC0 Public DomainA Ludwig Cancer Research study conducted in both mice and a small group of patients with advanced cancers has shown that so-called "cold&quo

Updated on: April 24,2024

A little radiation goes a long way in heating up cold tumors

by Ludwig Cancer ResearchCredit: CC0 Public DomainA Ludwig Cancer Research study conducted in both mice and a small group of patients with advanced cancers has shown that so-called "cold&quo

Updated on:April 24,2024

Researchers call for improved accessibility to specialist medical services during health care crises

by Keele UniversityCredit: Pixabay/CC0 Public DomainDelays for patients awaiting a diagnosis of an inflammatory arthritis, caused by changes in practice during the COVID pandemic, could have a ne

Updated on: May 23,2024

Researchers call for improved accessibility to specialist medical services during health care crises

by Keele UniversityCredit: Pixabay/CC0 Public DomainDelays for patients awaiting a diagnosis of an inflammatory arthritis, caused by changes in practice during the COVID pandemic, could have a ne

Updated on:May 23,2024

SARS-CoV-2 disrupts timing of immune response

by Charité - Universitätsmedizin BerlinAssay to detect the biochemical messenger TGFβ (COVID-19 research). Credit: Charité | Arne SattlerOnce an infection is under control, the body normally uses

Updated on: April 22,2024

SARS-CoV-2 disrupts timing of immune response

by Charité - Universitätsmedizin BerlinAssay to detect the biochemical messenger TGFβ (COVID-19 research). Credit: Charité | Arne SattlerOnce an infection is under control, the body normally uses

Updated on:April 22,2024

Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to

Updated on: September 07,2024

Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to

Updated on:September 07,2024

COVID-19 virus triggers antibodies from previous coronavirus infections: study

by The Translational Genomics Research InstituteCredit: CC0 Public DomainThe results of a study led by Northern Arizona University and the Translational Genomics Research Institute (TGen), an aff

Updated on: April 10,2024

COVID-19 virus triggers antibodies from previous coronavirus infections: study

by The Translational Genomics Research InstituteCredit: CC0 Public DomainThe results of a study led by Northern Arizona University and the Translational Genomics Research Institute (TGen), an aff

Updated on:April 10,2024

Rheumatoid arthritis linked to a lower risk of type 2 diabetes

by WileyCredit: CC0 Public DomainA recent analysis of a US commercial insurance database found that adults with rheumatoid arthritis had a lower risk of developing type 2 diabetes than other indi

Updated on: June 17,2024

Rheumatoid arthritis linked to a lower risk of type 2 diabetes

by WileyCredit: CC0 Public DomainA recent analysis of a US commercial insurance database found that adults with rheumatoid arthritis had a lower risk of developing type 2 diabetes than other indi

Updated on:June 17,2024

Differences in T cells' functional state determine resistance to cancer therapy

by Massachusetts Institute of TechnologyThe researchers took this image of a tumor using immunofluorescence, a technique that allows them to stain tissue sections with fluorescently-labeled antib

Updated on: May 08,2024

Differences in T cells' functional state determine resistance to cancer therapy

by Massachusetts Institute of TechnologyThe researchers took this image of a tumor using immunofluorescence, a technique that allows them to stain tissue sections with fluorescently-labeled antib

Updated on:May 08,2024

Adults with psoriasis more likely to have rheumatoid arthritis

(HealthDay)—Adults with psoriasis have an increased likelihood of having rheumatoid arthritis (RA) compared with adults without psoriasis, according to a study published online June 15 in theJou

Updated on: May 08,2024

Adults with psoriasis more likely to have rheumatoid arthritis

(HealthDay)—Adults with psoriasis have an increased likelihood of having rheumatoid arthritis (RA) compared with adults without psoriasis, according to a study published online June 15 in theJou

Updated on:May 08,2024

Prevalence of multimorbidity up in rheumatoid arthritis

Patients with rheumatoid arthritis (RA) have an increased prevalence of multimorbidity, according to a study recently published inRMD Open.Cynthia S. Crowson, Ph.D., from the Mayo Clinic in Roch

Updated on: June 17,2024

Prevalence of multimorbidity up in rheumatoid arthritis

Patients with rheumatoid arthritis (RA) have an increased prevalence of multimorbidity, according to a study recently published inRMD Open.Cynthia S. Crowson, Ph.D., from the Mayo Clinic in Roch

Updated on:June 17,2024

A messenger substance considered to be inflammatory can alleviate asthma symptoms

by Friedrich–Alexander University Erlangen–NurnbergIntranasal rIL-3 application during challenge induces Treg cells. (A) Experimental design for lung ILC2 skewing. (B) After 5 days of in vitro IL

Updated on: May 06,2024

A messenger substance considered to be inflammatory can alleviate asthma symptoms

by Friedrich–Alexander University Erlangen–NurnbergIntranasal rIL-3 application during challenge induces Treg cells. (A) Experimental design for lung ILC2 skewing. (B) After 5 days of in vitro IL

Updated on:May 06,2024

A common metabolite may help treat autoimmune diseases

by Hokkaido UniversityIn mice models with adoptive transfer experimental autoimmune encephalomyelitis, treatment with itaconate (right) greatly ameliorates the effects of the disease, compared to

Updated on: May 08,2024

A common metabolite may help treat autoimmune diseases

by Hokkaido UniversityIn mice models with adoptive transfer experimental autoimmune encephalomyelitis, treatment with itaconate (right) greatly ameliorates the effects of the disease, compared to

Updated on:May 08,2024