GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite

Updated on: April 08,2024

GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite

Updated on:April 08,2024

HDL composition may help predict health risks and design therapeutics

by Pat Bailey,UC DavisNutrition researcher Angela Zivkovic and colleagues have found that the amounts and specific structure of complex sugars called glycans can powerfully influence the body’s

Updated on: April 16,2024

HDL composition may help predict health risks and design therapeutics

by Pat Bailey,UC DavisNutrition researcher Angela Zivkovic and colleagues have found that the amounts and specific structure of complex sugars called glycans can powerfully influence the body’s

Updated on:April 16,2024

Study of infants and young children shows that offspring develop normally in mothers with rheumatic disease

by European League Against Rheumatism (EULAR)Credit: CC0 Public DomainAnkylosing spondylitis (AS) is a complex chronic inflammatory disease of the spine with involvement of the sacroiliac joints. Over

Updated on: June 26,2024

Study of infants and young children shows that offspring develop normally in mothers with rheumatic disease

by European League Against Rheumatism (EULAR)Credit: CC0 Public DomainAnkylosing spondylitis (AS) is a complex chronic inflammatory disease of the spine with involvement of the sacroiliac joints. Over

Updated on:June 26,2024

Long-term rituximab safe for patients with wegener's

Repeated and prolonged use of rituximab for B-cell depletion to treat relapses or maintain remission is safe and effective in patients with refractory granulomatosis with polyangiitis (GPA; Wegener&#3

Updated on: March 28,2024

Long-term rituximab safe for patients with wegener's

Repeated and prolonged use of rituximab for B-cell depletion to treat relapses or maintain remission is safe and effective in patients with refractory granulomatosis with polyangiitis (GPA; Wegener&#3

Updated on:March 28,2024

Study finds TNF inhibitor more effective with regular serum assessment to adjust dose

by American College of RheumatologyCredit: Unsplash/CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that pro

Updated on: June 28,2024

Study finds TNF inhibitor more effective with regular serum assessment to adjust dose

by American College of RheumatologyCredit: Unsplash/CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that pro

Updated on:June 28,2024

Differences in T cells' functional state determine resistance to cancer therapy

by Massachusetts Institute of TechnologyThe researchers took this image of a tumor using immunofluorescence, a technique that allows them to stain tissue sections with fluorescently-labeled antib

Updated on: May 08,2024

Differences in T cells' functional state determine resistance to cancer therapy

by Massachusetts Institute of TechnologyThe researchers took this image of a tumor using immunofluorescence, a technique that allows them to stain tissue sections with fluorescently-labeled antib

Updated on:May 08,2024

CAR T therapy shows long-lasting remissions in non-hodgkin lymphoma

by Perelman School of Medicine at the University of PennsylvaniaCredit: Unsplash/CC0 Public DomainA significant number of non-Hodgkin lymphoma (NHL) patients in a Penn Medicine-initiated clinical

Updated on: April 08,2024

CAR T therapy shows long-lasting remissions in non-hodgkin lymphoma

by Perelman School of Medicine at the University of PennsylvaniaCredit: Unsplash/CC0 Public DomainA significant number of non-Hodgkin lymphoma (NHL) patients in a Penn Medicine-initiated clinical

Updated on:April 08,2024

A messenger substance considered to be inflammatory can alleviate asthma symptoms

by Friedrich–Alexander University Erlangen–NurnbergIntranasal rIL-3 application during challenge induces Treg cells. (A) Experimental design for lung ILC2 skewing. (B) After 5 days of in vitro IL

Updated on: May 06,2024

A messenger substance considered to be inflammatory can alleviate asthma symptoms

by Friedrich–Alexander University Erlangen–NurnbergIntranasal rIL-3 application during challenge induces Treg cells. (A) Experimental design for lung ILC2 skewing. (B) After 5 days of in vitro IL

Updated on:May 06,2024

COVID-19 model reveals key role for innate immunity in controlling viral load

by American Chemical SocietyColorized scanning electron micrograph of a cell (blue) heavily infected with SARS-CoV-2 virus particles (red), isolated from a patient sample. Image captured at the N

Updated on: April 10,2024

COVID-19 model reveals key role for innate immunity in controlling viral load

by American Chemical SocietyColorized scanning electron micrograph of a cell (blue) heavily infected with SARS-CoV-2 virus particles (red), isolated from a patient sample. Image captured at the N

Updated on:April 10,2024

Expensive arthritis treatment no better than steroid therapy

by Hospital for Special Surgery“On average, each of the therapies resulted in clinically meaningful improvement in pain,” said Lisa Mandl, M.D., MPH, a rheumatologist at Hospital for Special Surg

Updated on: March 24,2024

Expensive arthritis treatment no better than steroid therapy

by Hospital for Special Surgery“On average, each of the therapies resulted in clinically meaningful improvement in pain,” said Lisa Mandl, M.D., MPH, a rheumatologist at Hospital for Special Surg

Updated on:March 24,2024

Inulin-gel-based oral immunotherapy may offer long-awaited treatment for food allergy sufferers

byUniversity of MichiganInulin gel/OVA protects mice against repeated allergen challenges with chicken egg white. Credit:Nature Materials(2024). DOI: 10.1038/s41563-024-01909-wA stud

Updated on: July 10,2024

Inulin-gel-based oral immunotherapy may offer long-awaited treatment for food allergy sufferers

byUniversity of MichiganInulin gel/OVA protects mice against repeated allergen challenges with chicken egg white. Credit:Nature Materials(2024). DOI: 10.1038/s41563-024-01909-wA stud

Updated on:July 10,2024

Enhanced stability of tristetraprolin found to promote bone health and reduce frailty

by International Association for Dental, Oral, and Craniofacial ResearchCredit: Unsplash/CC0 Public DomainA study used a novel transgenic mouse model (TTP knock-in—TTPKI) that has a moderate elevation

Updated on: March 27,2024

Enhanced stability of tristetraprolin found to promote bone health and reduce frailty

by International Association for Dental, Oral, and Craniofacial ResearchCredit: Unsplash/CC0 Public DomainA study used a novel transgenic mouse model (TTP knock-in—TTPKI) that has a moderate elevation

Updated on:March 27,2024