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Immunology & Rheumatology
Focuses on rheumatic and immune diseases.
Sub Categories on Immunology & Rheumatology
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Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

by Bob Yirka , Medical XpressPerturbation of X-inactivation in immune cells ofFtx−/−females.(A) Map of the X inactivation center showing the location ofXist(green) andFtx

Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

by Bob Yirka , Medical XpressPerturbation of X-inactivation in immune cells ofFtx−/−females.(A) Map of the X inactivation center showing the location ofXist(green) andFtx
High false negative rate with PFTs in scleroderma lung disease

High false negative rate with PFTs in scleroderma lung disease

(HealthDay)—Use of pulmonary function tests (PFTs) is associated with high false negative rates for detection of scleroderma-associated interstitial lung disease (SSc-ILD), according to a study publis

High false negative rate with PFTs in scleroderma lung disease

(HealthDay)—Use of pulmonary function tests (PFTs) is associated with high false negative rates for detection of scleroderma-associated interstitial lung disease (SSc-ILD), according to a study publis
Identification of LZTR1 leads to novel insights into RAS-driven diseases

Identification of LZTR1 leads to novel insights into RAS-driven diseases

by VIB (the Flanders Institute for Biotechnology)Cancer cell during cell division. Credit: National Institutes of HealthMutations in RAS proteins initiate many of the most aggressive tumors, and

Identification of LZTR1 leads to novel insights into RAS-driven diseases

by VIB (the Flanders Institute for Biotechnology)Cancer cell during cell division. Credit: National Institutes of HealthMutations in RAS proteins initiate many of the most aggressive tumors, and
OCTAVE study reveals vaccine responses in patients with impaired immune systems

OCTAVE study reveals vaccine responses in patients with impaired immune systems

by University of GlasgowCredit: Pixabay/CC0 Public DomainThe OCTAVE study—a multi-center, UK-wide trial, led by the University of Glasgow and co-ordinated by the University of Birmingham's Ca

OCTAVE study reveals vaccine responses in patients with impaired immune systems

by University of GlasgowCredit: Pixabay/CC0 Public DomainThe OCTAVE study—a multi-center, UK-wide trial, led by the University of Glasgow and co-ordinated by the University of Birmingham's Ca
New vaccine protects from widespread, costly infection, mice study shows

New vaccine protects from widespread, costly infection, mice study shows

by American Society for MicrobiologyCredit: CC0 Public DomainA newly developed experimental vaccine was more than eighty percent effective in protecting mice from succumbing toStaphylococcu

New vaccine protects from widespread, costly infection, mice study shows

by American Society for MicrobiologyCredit: CC0 Public DomainA newly developed experimental vaccine was more than eighty percent effective in protecting mice from succumbing toStaphylococcu
Disease control, safe medications critical to pregnancies for women with rheumatic disease

Disease control, safe medications critical to pregnancies for women with rheumatic disease

by UT Southwestern Medical CenterCredit: Pixabay/CC0 Public DomainPregnant women with active rheumatic disease carry a higher risk of adverse outcomes than the general population including hypert

Disease control, safe medications critical to pregnancies for women with rheumatic disease

by UT Southwestern Medical CenterCredit: Pixabay/CC0 Public DomainPregnant women with active rheumatic disease carry a higher risk of adverse outcomes than the general population including hypert
Radiation-free screening can identify interstitial lung involvement in rheumatoid arthritis

Radiation-free screening can identify interstitial lung involvement in rheumatoid arthritis

by Elana GotkineFor asymptomatic rheumatoid arthritis (RA) patients, a new radiation-free screening protocol can identify suspected interstitial lung involvement (ILI), according to a studypubli

Radiation-free screening can identify interstitial lung involvement in rheumatoid arthritis

by Elana GotkineFor asymptomatic rheumatoid arthritis (RA) patients, a new radiation-free screening protocol can identify suspected interstitial lung involvement (ILI), according to a studypubli
Can a DNA construction kit replace expensive antibody medication?

Can a DNA construction kit replace expensive antibody medication?

by KU LeuvenCredit: CC0 Public DomainResearchers at KU Leuven in Belgium have developed a technique to make sheep produce new antibodies simply by injecting the DNA building blocks. This approach

Can a DNA construction kit replace expensive antibody medication?

by KU LeuvenCredit: CC0 Public DomainResearchers at KU Leuven in Belgium have developed a technique to make sheep produce new antibodies simply by injecting the DNA building blocks. This approach
COVID-19 can cause severe inflammation in the brain

COVID-19 can cause severe inflammation in the brain

by Albert Ludwigs University of FreiburgGraphical Abstract. Credit:Immunity(2021). DOI: 10.1016/j.immuni.2021.06.002Both during and after infection with the Coronavirus SARS-CoV-2, pa

COVID-19 can cause severe inflammation in the brain

by Albert Ludwigs University of FreiburgGraphical Abstract. Credit:Immunity(2021). DOI: 10.1016/j.immuni.2021.06.002Both during and after infection with the Coronavirus SARS-CoV-2, pa
Macrophages produce heat from brown adipose tissue in response to cold, study reveals

Macrophages produce heat from brown adipose tissue in response to cold, study reveals

by University of TsukubaGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113978Researchers from University of Tsukuba have elucidated the molecular mechanism

Macrophages produce heat from brown adipose tissue in response to cold, study reveals

by University of TsukubaGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113978Researchers from University of Tsukuba have elucidated the molecular mechanism
Study shows autoantibodies behind lifelong risk of viral infection

Study shows autoantibodies behind lifelong risk of viral infection

byUniversity of ZurichCredit: CC0 Public DomainA new study,publishedin theJournal of Experimental Medicine, shows that about 2% of the population develop autoantibodies against

Study shows autoantibodies behind lifelong risk of viral infection

byUniversity of ZurichCredit: CC0 Public DomainA new study,publishedin theJournal of Experimental Medicine, shows that about 2% of the population develop autoantibodies against
Using molecular scissors to improve CAR-T cell therapy

Using molecular scissors to improve CAR-T cell therapy

by Susan Buckles,Mayo ClinicAn in vitro model for chronic stimulation induces phenotypic and functional signs of exhaustion in CART19-28ζ cells. Credit:Nature Communications(2024). D

Using molecular scissors to improve CAR-T cell therapy

by Susan Buckles,Mayo ClinicAn in vitro model for chronic stimulation induces phenotypic and functional signs of exhaustion in CART19-28ζ cells. Credit:Nature Communications(2024). D