GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite

Updated on: April 08,2024

GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite

Updated on:April 08,2024

New pathway in immune defense discovered: Interaction of monocytes and platelets decoded

by Inka Väth,University Hospital Bonn(from left) Dr. Ibrahim Hawwari, Prof. Bernardo Franklin and Lukas Roßnagel discover new intercellular communication mechanism in which blood platelets, so-c

Updated on: July 09,2024

New pathway in immune defense discovered: Interaction of monocytes and platelets decoded

by Inka Väth,University Hospital Bonn(from left) Dr. Ibrahim Hawwari, Prof. Bernardo Franklin and Lukas Roßnagel discover new intercellular communication mechanism in which blood platelets, so-c

Updated on:July 09,2024

Air pollution exposure tied to new psoriasis

by Lori SolomonLong-term exposure to air pollution is associated with the development of new psoriasis, according to a studypublishedonline July 16 inJAMA Network Open.Junhui Wu, Ph.

Updated on: July 23,2024

Air pollution exposure tied to new psoriasis

by Lori SolomonLong-term exposure to air pollution is associated with the development of new psoriasis, according to a studypublishedonline July 16 inJAMA Network Open.Junhui Wu, Ph.

Updated on:July 23,2024

Long-term rituximab safe for patients with wegener's

Repeated and prolonged use of rituximab for B-cell depletion to treat relapses or maintain remission is safe and effective in patients with refractory granulomatosis with polyangiitis (GPA; Wegener&#3

Updated on: March 28,2024

Long-term rituximab safe for patients with wegener's

Repeated and prolonged use of rituximab for B-cell depletion to treat relapses or maintain remission is safe and effective in patients with refractory granulomatosis with polyangiitis (GPA; Wegener&#3

Updated on:March 28,2024

Proteinuria level predicts renal outcome in lupus nephritis

(HealthDay)—Proteinuria levels at 12 months are the best predictor of long-term renal outcome in patients with lupus nephritis, according to a study published in the May issue ofArthritis &

Updated on: March 24,2024

Proteinuria level predicts renal outcome in lupus nephritis

(HealthDay)—Proteinuria levels at 12 months are the best predictor of long-term renal outcome in patients with lupus nephritis, according to a study published in the May issue ofArthritis &

Updated on:March 24,2024

A common metabolite may help treat autoimmune diseases

by Hokkaido UniversityIn mice models with adoptive transfer experimental autoimmune encephalomyelitis, treatment with itaconate (right) greatly ameliorates the effects of the disease, compared to

Updated on: May 08,2024

A common metabolite may help treat autoimmune diseases

by Hokkaido UniversityIn mice models with adoptive transfer experimental autoimmune encephalomyelitis, treatment with itaconate (right) greatly ameliorates the effects of the disease, compared to

Updated on:May 08,2024

Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to

Updated on: September 07,2024

Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to

Updated on:September 07,2024

Evidence for link between 'leaky gut' and autoantibody production in HIV-positive patients

by Medical University of South CarolinaHIV-positive, ART-treated patients with high levels of autoantibodies also have increased levels of bacteria (Staphylococcus aureus) products in their blood

Updated on: April 16,2024

Evidence for link between 'leaky gut' and autoantibody production in HIV-positive patients

by Medical University of South CarolinaHIV-positive, ART-treated patients with high levels of autoantibodies also have increased levels of bacteria (Staphylococcus aureus) products in their blood

Updated on:April 16,2024

T cells take the lead in controlling SARS-CoV-2 and reducing COVID-19 disease severity

by La Jolla Institute for ImmunologyA multi-layered, virus-specific immune response is important for controlling the virus during the acute phase of the infection and reducing COVID-19 disease se

Updated on: April 24,2024

T cells take the lead in controlling SARS-CoV-2 and reducing COVID-19 disease severity

by La Jolla Institute for ImmunologyA multi-layered, virus-specific immune response is important for controlling the virus during the acute phase of the infection and reducing COVID-19 disease se

Updated on:April 24,2024

Subclinical atherosclerosis noted in diffuse scleroderma

Patients with diffuse systemic sclerosis, without any clinical evidence of cardiovascular disease, have indicators of subclinical atherosclerosis, according to a study published online Aug. 16 in&nbsp

Updated on: March 24,2024

Subclinical atherosclerosis noted in diffuse scleroderma

Patients with diffuse systemic sclerosis, without any clinical evidence of cardiovascular disease, have indicators of subclinical atherosclerosis, according to a study published online Aug. 16 in&nbsp

Updated on:March 24,2024

A new open-access portal for human immunology data and tools

by Rachel Tompa,Allen Institute for Brain ScienceTEA-seq single panel cell type data from Human Immune System Explorer. Credit: Zach Thomson/Allen InstituteResearchers at the Allen Institute for

Updated on: May 05,2024

A new open-access portal for human immunology data and tools

by Rachel Tompa,Allen Institute for Brain ScienceTEA-seq single panel cell type data from Human Immune System Explorer. Credit: Zach Thomson/Allen InstituteResearchers at the Allen Institute for

Updated on:May 05,2024

Adherence to mediterranean diet not linked to risk of RA

(HealthDay)—Adherence to a Mediterranean diet is not associated with incidence of rheumatoid arthritis (RA) in U.S. women, according to a study published in the May issue ofArthritis Care &

Updated on: April 08,2024

Adherence to mediterranean diet not linked to risk of RA

(HealthDay)—Adherence to a Mediterranean diet is not associated with incidence of rheumatoid arthritis (RA) in U.S. women, according to a study published in the May issue ofArthritis Care &

Updated on:April 08,2024