A metabolic enzyme as a potential new target for cancer immune therapies

by German Cancer Research CenterCredit: Unsplash/CC0 Public DomainThe metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system. This wa

Updated on: May 07,2024

A metabolic enzyme as a potential new target for cancer immune therapies

by German Cancer Research CenterCredit: Unsplash/CC0 Public DomainThe metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system. This wa

Updated on:May 07,2024

Patient-driven discovery reveals potential target for autoimmune diseases

by Isabella Backman,Yale UniversityModel summarizing the function of PI3Kγ in antibody responses. Credit:Nature Immunology(2024). DOI: 10.1038/s41590-024-01890-1A medical mystery ser

Updated on: July 17,2024

Patient-driven discovery reveals potential target for autoimmune diseases

by Isabella Backman,Yale UniversityModel summarizing the function of PI3Kγ in antibody responses. Credit:Nature Immunology(2024). DOI: 10.1038/s41590-024-01890-1A medical mystery ser

Updated on:July 17,2024

Respiratory allergies: Newly discovered molecule plays a major role in triggering inflammation

byCNRSMicroscopic visualization of immune cells (in green) activated by the alarmins TL1A and interleukin-33 during the onset of allergic inflammation in the lungs. ILC2s immune cells produce la

Updated on: April 28,2024

Respiratory allergies: Newly discovered molecule plays a major role in triggering inflammation

byCNRSMicroscopic visualization of immune cells (in green) activated by the alarmins TL1A and interleukin-33 during the onset of allergic inflammation in the lungs. ILC2s immune cells produce la

Updated on:April 28,2024

Researchers unlock predictive biomarkers for common hip disorder

by University of MissouriBoxplots of significantly different median urine biomarker concentrations between the DDH cohort and healthy controls (P < 0.05). Median and the interquartile range ar

Updated on: May 19,2024

Researchers unlock predictive biomarkers for common hip disorder

by University of MissouriBoxplots of significantly different median urine biomarker concentrations between the DDH cohort and healthy controls (P < 0.05). Median and the interquartile range ar

Updated on:May 19,2024

New evidence that 'gout' strongly runs in the family

by University of NottinghamIt's historically known as 'the king of diseases and the disease of kings' and was long thought to be caused by an overindulgent lifestyle, but now scientis

Updated on: March 24,2024

New evidence that 'gout' strongly runs in the family

by University of NottinghamIt's historically known as 'the king of diseases and the disease of kings' and was long thought to be caused by an overindulgent lifestyle, but now scientis

Updated on:March 24,2024

Depemokimab cuts exacerbation rate in eosinophilic asthma

by Elana GotkineFor patients with severe asthma with an eosinophilic phenotype, depemokimab reduces the annualized rate of exacerbations, according to a studypublishedonline Sept. 9 in the

Updated on: October 01,2024

Depemokimab cuts exacerbation rate in eosinophilic asthma

by Elana GotkineFor patients with severe asthma with an eosinophilic phenotype, depemokimab reduces the annualized rate of exacerbations, according to a studypublishedonline Sept. 9 in the

Updated on:October 01,2024

Drug shows promise against arthritis common in people with psoriasis

by Steven Reinberg, Healthday ReporterNew medication improved skin condition, lessened swelling, study finds.(HealthDay)—A new drug called brodalumab appears to be effective in treating patients suffe

Updated on: March 24,2024

Drug shows promise against arthritis common in people with psoriasis

by Steven Reinberg, Healthday ReporterNew medication improved skin condition, lessened swelling, study finds.(HealthDay)—A new drug called brodalumab appears to be effective in treating patients suffe

Updated on:March 24,2024

Guidance for coronary patients with ASA/NSAID sensitivity

(HealthDay)—In patients with stable chronic ischemic heart disease (CIHD) and histories of nonsevere hypersensitivity reactions to acetylsalicylic acid (ASA)/nonsteroidal anti-inflammatory drugs (NSAI

Updated on: April 08,2024

Guidance for coronary patients with ASA/NSAID sensitivity

(HealthDay)—In patients with stable chronic ischemic heart disease (CIHD) and histories of nonsevere hypersensitivity reactions to acetylsalicylic acid (ASA)/nonsteroidal anti-inflammatory drugs (NSAI

Updated on:April 08,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on: May 07,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on:May 07,2024

Study suggests parents' understanding of atopic dermatitis may influence child's diet

byAmerican College of Allergy, Asthma, and ImmunologyCredit: CC0 Public DomainParents of children with atopic dermatitis (AD, also called eczema) know that the allergic condition can mean a heig

Updated on: October 30,2024

Study suggests parents' understanding of atopic dermatitis may influence child's diet

byAmerican College of Allergy, Asthma, and ImmunologyCredit: CC0 Public DomainParents of children with atopic dermatitis (AD, also called eczema) know that the allergic condition can mean a heig

Updated on:October 30,2024

Compound found to trigger innate immunity against viruses

by Bobbi Nodell,University of WashingtonCells under a microscope in a UW Medicine immunity lab. Credit: Dennis WiseResearch from UW Medicine and collaborators indicates that a drug-like molecule

Updated on: May 08,2024

Compound found to trigger innate immunity against viruses

by Bobbi Nodell,University of WashingtonCells under a microscope in a UW Medicine immunity lab. Credit: Dennis WiseResearch from UW Medicine and collaborators indicates that a drug-like molecule

Updated on:May 08,2024

Continuation vs. discontinuation of bDMARDs during the perioperative period

by Wolters Kluwer HealthCredit: Pixabay/CC0 Public DomainFor patients with rheumatic arthritis and other chronic inflammatory diseases, discontinuing biologic disease-modifying anti-rheumatic dru

Updated on: June 26,2024

Continuation vs. discontinuation of bDMARDs during the perioperative period

by Wolters Kluwer HealthCredit: Pixabay/CC0 Public DomainFor patients with rheumatic arthritis and other chronic inflammatory diseases, discontinuing biologic disease-modifying anti-rheumatic dru

Updated on:June 26,2024