The positive and negative role of LRH-1 during inflammation

by University of KonstanzDetection of immune cells using specific antibodies in tissue sections of the spleen of wild type animals (left panel) and mice with T cell-specific deletion of LRH-1 (ri

Updated on: April 16,2024

The positive and negative role of LRH-1 during inflammation

by University of KonstanzDetection of immune cells using specific antibodies in tissue sections of the spleen of wild type animals (left panel) and mice with T cell-specific deletion of LRH-1 (ri

Updated on:April 16,2024

Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

by Bob Yirka , Medical XpressPerturbation of X-inactivation in immune cells ofFtx−/−females.(A) Map of the X inactivation center showing the location ofXist(green) andFtx

Updated on: May 30,2024

Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

by Bob Yirka , Medical XpressPerturbation of X-inactivation in immune cells ofFtx−/−females.(A) Map of the X inactivation center showing the location ofXist(green) andFtx

Updated on:May 30,2024

How COVID-19 triggers massive inflammation

by Children's Hospital BostonSARS-CoV-2 (shown here in an electron microscopy image). Credit: National Institute of Allergy and Infectious Diseases, NIHA study led by researchers at Boston Ch

Updated on: April 13,2024

How COVID-19 triggers massive inflammation

by Children's Hospital BostonSARS-CoV-2 (shown here in an electron microscopy image). Credit: National Institute of Allergy and Infectious Diseases, NIHA study led by researchers at Boston Ch

Updated on:April 13,2024

Early signs of arthritis can be found in the mouth

by University of AdelaideThis is a hand afflicted by rheumatoid arthritis. Credit: The University of ManchesterA common gum disease may indicate a person's risk of developing rheumatoid arthr

Updated on: April 20,2024

Early signs of arthritis can be found in the mouth

by University of AdelaideThis is a hand afflicted by rheumatoid arthritis. Credit: The University of ManchesterA common gum disease may indicate a person's risk of developing rheumatoid arthr

Updated on:April 20,2024

Rheumatoid arthritis can be costly

Study looked at direct health care spending, worker productivity.(HealthDay)—Workers with rheumatoid arthritis have higher health care and other costs for U.S. employers than workers without the condi

Updated on: March 24,2024

Rheumatoid arthritis can be costly

Study looked at direct health care spending, worker productivity.(HealthDay)—Workers with rheumatoid arthritis have higher health care and other costs for U.S. employers than workers without the condi

Updated on:March 24,2024

Study: Why people with knee osteoarthritis experience different kinds of pain

by Boston University School of MedicineCredit: CC0 Public DomainOsteoarthritis is the most common form of arthritis worldwide, affecting more than 300 million people. It causes substantial pain,

Updated on: April 17,2024

Study: Why people with knee osteoarthritis experience different kinds of pain

by Boston University School of MedicineCredit: CC0 Public DomainOsteoarthritis is the most common form of arthritis worldwide, affecting more than 300 million people. It causes substantial pain,

Updated on:April 17,2024

CRISPR study reveals new immune system regulators

by Wellcome Trust Sanger InstituteCRISPR-associated protein Cas9 (white) from Staphylococcus aureus based on Protein Database ID 5AXW. Credit: Thomas Splettstoesser (Wikipedia, CC BY-SA 4.0)Scien

Updated on: April 13,2024

CRISPR study reveals new immune system regulators

by Wellcome Trust Sanger InstituteCRISPR-associated protein Cas9 (white) from Staphylococcus aureus based on Protein Database ID 5AXW. Credit: Thomas Splettstoesser (Wikipedia, CC BY-SA 4.0)Scien

Updated on:April 13,2024

Analysis of DNA reveals weapons used by our immune cells to fight tuberculosis

by Agency for Science, Technology and Research (A*STAR), SingaporeFig. 1: Histone acetylome-wide association study of TB. Credit: DOI: 10.1038/s41564-021-01049-wA study led by the Agency for Scie

Updated on: April 15,2024

Analysis of DNA reveals weapons used by our immune cells to fight tuberculosis

by Agency for Science, Technology and Research (A*STAR), SingaporeFig. 1: Histone acetylome-wide association study of TB. Credit: DOI: 10.1038/s41564-021-01049-wA study led by the Agency for Scie

Updated on:April 15,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on: May 07,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on:May 07,2024

A metabolic enzyme as a potential new target for cancer immune therapies

by German Cancer Research CenterCredit: Unsplash/CC0 Public DomainThe metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system. This wa

Updated on: May 07,2024

A metabolic enzyme as a potential new target for cancer immune therapies

by German Cancer Research CenterCredit: Unsplash/CC0 Public DomainThe metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system. This wa

Updated on:May 07,2024

Swimming short fibrous nasal drops achieve intraventricular administration

byScience China PressInspired by swimming fish and the microstructure of the nasal cavity, short-swimming fibrous nasal drops with the ability to transport drugs along the nasal mucosa were inno

Updated on: April 28,2024

Swimming short fibrous nasal drops achieve intraventricular administration

byScience China PressInspired by swimming fish and the microstructure of the nasal cavity, short-swimming fibrous nasal drops with the ability to transport drugs along the nasal mucosa were inno

Updated on:April 28,2024

How B cells are programmed early in life can impact long-term immune health

by Lund UniversityGraphical abstract. Credit:Immunity(2022). DOI: 10.1016/j.immuni.2022.08.018B cells and the antibodies they produce play an important role in our immune system, prot

Updated on: April 08,2024

How B cells are programmed early in life can impact long-term immune health

by Lund UniversityGraphical abstract. Credit:Immunity(2022). DOI: 10.1016/j.immuni.2022.08.018B cells and the antibodies they produce play an important role in our immune system, prot

Updated on:April 08,2024