Research unveils metabolic strategies to enhance CAR-T cell therapy

by Cactus CommunicationsChimeric antigen receptor T (CAR-T) cell therapy effectively treats hematological tumors but struggles due to metabolic challenges in the tumor microenvironment. Tumor cells di

Updated on: March 27,2024 0

Research unveils metabolic strategies to enhance CAR-T cell therapy

by Cactus CommunicationsChimeric antigen receptor T (CAR-T) cell therapy effectively treats hematological tumors but struggles due to metabolic challenges in the tumor microenvironment. Tumor cells di

Updated on:March 27,2024 0

Curbing blood cancers by teaching immune cells to kill mutant stem cells

by Nancy Fliesler,Children's Hospital BostonROS and TLR3 signaling mediates the "eat-me" and "don't eat me" signals that determine stem cell clonal selection by macro

Updated on: October 24,2024 0

Curbing blood cancers by teaching immune cells to kill mutant stem cells

by Nancy Fliesler,Children's Hospital BostonROS and TLR3 signaling mediates the "eat-me" and "don't eat me" signals that determine stem cell clonal selection by macro

Updated on:October 24,2024 0

Long-term rituximab safe for patients with wegener's

Repeated and prolonged use of rituximab for B-cell depletion to treat relapses or maintain remission is safe and effective in patients with refractory granulomatosis with polyangiitis (GPA; Wegener&#3

Updated on: March 28,2024 17

Long-term rituximab safe for patients with wegener's

Repeated and prolonged use of rituximab for B-cell depletion to treat relapses or maintain remission is safe and effective in patients with refractory granulomatosis with polyangiitis (GPA; Wegener&#3

Updated on:March 28,2024 17

Greater support needed to improve the treatment of knee osteoarthritis

by Curtin UniversityCredit: CC0 Public DomainA new Curtin University-led paper has outlined that many people living with knee osteoarthritis may be needlessly suffering or receiving the wrong tre

Updated on: May 23,2024 5

Greater support needed to improve the treatment of knee osteoarthritis

by Curtin UniversityCredit: CC0 Public DomainA new Curtin University-led paper has outlined that many people living with knee osteoarthritis may be needlessly suffering or receiving the wrong tre

Updated on:May 23,2024 5

Key type of immune cell 'self-renews' in humans, new study finds

by Cardiff UniversityCredit: CC0 Public DomainA team of scientists has shown that a key type of immune cell "self-renews" in humans.It is an unexpected discovery, as it was previously t

Updated on: April 24,2024 16

Key type of immune cell 'self-renews' in humans, new study finds

by Cardiff UniversityCredit: CC0 Public DomainA team of scientists has shown that a key type of immune cell "self-renews" in humans.It is an unexpected discovery, as it was previously t

Updated on:April 24,2024 16

The secret lives of T cell receptors and their role in the immune response

by Delthia Ricks , Medical XpressCredit: CC0 Public DomainCanadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components inte

Updated on: May 05,2024 12

The secret lives of T cell receptors and their role in the immune response

by Delthia Ricks , Medical XpressCredit: CC0 Public DomainCanadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components inte

Updated on:May 05,2024 12

T-cells shown to infiltrate brain, cause respiratory distress in condition affecting the immunocompromised

by Liz Ahlberg Touchstone |,University of Illinois at Urbana-ChampaignPulmonary dysfunction and mortality under the C-IRIS condition.ASchematic representation of the experiments and

Updated on: May 05,2024 13

T-cells shown to infiltrate brain, cause respiratory distress in condition affecting the immunocompromised

by Liz Ahlberg Touchstone |,University of Illinois at Urbana-ChampaignPulmonary dysfunction and mortality under the C-IRIS condition.ASchematic representation of the experiments and

Updated on:May 05,2024 13

Investigating healthy lifestyle and mortality in osteoarthritis

by European Alliance of Associations for Rheumatology (EULAR)Credit: CC0 Public DomainHealthy lifestyles are thought to reduce mortality in the general population, but it is not known whether the same

Updated on: April 17,2024 20

Investigating healthy lifestyle and mortality in osteoarthritis

by European Alliance of Associations for Rheumatology (EULAR)Credit: CC0 Public DomainHealthy lifestyles are thought to reduce mortality in the general population, but it is not known whether the same

Updated on:April 17,2024 20

Epigenetics alters genes in rheumatoid arthritis

by University of California - San DiegoIn this artist's rendering, a DNA molecule is methylated on both strands at the center cytosine. DNA methylation plays an important role in epigenetic g

Updated on: March 24,2024 14

Epigenetics alters genes in rheumatoid arthritis

by University of California - San DiegoIn this artist's rendering, a DNA molecule is methylated on both strands at the center cytosine. DNA methylation plays an important role in epigenetic g

Updated on:March 24,2024 14

First-in-human trial with CAR macrophages shows promise targeting solid tumors

by Caren Begun,University of PennsylvaniaCredit: Pixabay/CC0 Public DomainPreliminary findings from Penn Medicine in an ongoing first-in-human clinical trial examining the safety, tolerability a

Updated on: April 09,2024 19

First-in-human trial with CAR macrophages shows promise targeting solid tumors

by Caren Begun,University of PennsylvaniaCredit: Pixabay/CC0 Public DomainPreliminary findings from Penn Medicine in an ongoing first-in-human clinical trial examining the safety, tolerability a

Updated on:April 09,2024 19

Proportion of adults diagnosed with inflammatory arthritis in England has increased by more than 40%

by Keele UniversityPercentage of patients with at least 1 Read/SNOMED code for RA who meet the diagnosis algorithm. Panel A = percentage of patients ever receiving an RA Read/SNOMED code that mee

Updated on: March 28,2024 11

Proportion of adults diagnosed with inflammatory arthritis in England has increased by more than 40%

by Keele UniversityPercentage of patients with at least 1 Read/SNOMED code for RA who meet the diagnosis algorithm. Panel A = percentage of patients ever receiving an RA Read/SNOMED code that mee

Updated on:March 28,2024 11

SARS-CoV-2 variant B.1.617 attacks immune system

by The German Primate CenterThe spike protein on the surface of SARS-CoV-2 virions mediates entry into target cells. It Is the main target for neutralizing antibodies that are produced following

Updated on: April 22,2024 20

SARS-CoV-2 variant B.1.617 attacks immune system

by The German Primate CenterThe spike protein on the surface of SARS-CoV-2 virions mediates entry into target cells. It Is the main target for neutralizing antibodies that are produced following

Updated on:April 22,2024 20