Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on: May 07,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on:May 07,2024

MAIT cell activation may play a role in fatal outcomes among severe COVID-19 cases

by Public Library of ScienceProject design and overall conclusions of the St George’s, University of London and University of Oxford collaboration on immune parameters of ICU COVID-19 and severe

Updated on: April 20,2024

MAIT cell activation may play a role in fatal outcomes among severe COVID-19 cases

by Public Library of ScienceProject design and overall conclusions of the St George’s, University of London and University of Oxford collaboration on immune parameters of ICU COVID-19 and severe

Updated on:April 20,2024

Synthetic immunology: Approaching a turning point in the treatment and prevention of disease

byHeidelberg UniversityTop-down versus bottom-up synthetic immunology. Credit:Nature Nanotechnology(2024). DOI: 10.1038/s41565-024-01744-9Synthetic immunology, an innovative field of

Updated on: September 04,2024

Synthetic immunology: Approaching a turning point in the treatment and prevention of disease

byHeidelberg UniversityTop-down versus bottom-up synthetic immunology. Credit:Nature Nanotechnology(2024). DOI: 10.1038/s41565-024-01744-9Synthetic immunology, an innovative field of

Updated on:September 04,2024

Swimming short fibrous nasal drops achieve intraventricular administration

byScience China PressInspired by swimming fish and the microstructure of the nasal cavity, short-swimming fibrous nasal drops with the ability to transport drugs along the nasal mucosa were inno

Updated on: April 28,2024

Swimming short fibrous nasal drops achieve intraventricular administration

byScience China PressInspired by swimming fish and the microstructure of the nasal cavity, short-swimming fibrous nasal drops with the ability to transport drugs along the nasal mucosa were inno

Updated on:April 28,2024

Mpox: Characterization of post-infectious immune response

by Pasteur InstituteHuman cells infected with MPXV (in green) among uninfected cells (nuclei in blue). Image taken with a confocal microscope. Credit: Mathieu Hubert and Olivier Schwartz, Institu

Updated on: April 20,2024

Mpox: Characterization of post-infectious immune response

by Pasteur InstituteHuman cells infected with MPXV (in green) among uninfected cells (nuclei in blue). Image taken with a confocal microscope. Credit: Mathieu Hubert and Olivier Schwartz, Institu

Updated on:April 20,2024

Lithium may protect against cartilage decline in osteoarthritis

(HealthDay)—Lithium reduces catabolic events in interleukin-1 β (IL-1β)-treated human articular chondrocytes and protects against cartilage degradation in IL-1β-treated mouse knee joints, according to

Updated on: March 24,2024

Lithium may protect against cartilage decline in osteoarthritis

(HealthDay)—Lithium reduces catabolic events in interleukin-1 β (IL-1β)-treated human articular chondrocytes and protects against cartilage degradation in IL-1β-treated mouse knee joints, according to

Updated on:March 24,2024

Study: Why people with knee osteoarthritis experience different kinds of pain

by Boston University School of MedicineCredit: CC0 Public DomainOsteoarthritis is the most common form of arthritis worldwide, affecting more than 300 million people. It causes substantial pain,

Updated on: April 17,2024

Study: Why people with knee osteoarthritis experience different kinds of pain

by Boston University School of MedicineCredit: CC0 Public DomainOsteoarthritis is the most common form of arthritis worldwide, affecting more than 300 million people. It causes substantial pain,

Updated on:April 17,2024

Can gut bacteria cause rheumatoid arthritis?

by Greg Glasgow,CU Anschutz Medical CampusCredit: Pixabay/CC0 Public DomainResearchers at the University of Colorado School of Medicine have discovered that a unique bacteria found in the gut co

Updated on: April 20,2024

Can gut bacteria cause rheumatoid arthritis?

by Greg Glasgow,CU Anschutz Medical CampusCredit: Pixabay/CC0 Public DomainResearchers at the University of Colorado School of Medicine have discovered that a unique bacteria found in the gut co

Updated on:April 20,2024

How lockdown impacts those with bone, joint and muscle pain

by University of East AngliaCredit: CC0 Public DomainUniversity of East Anglia researchers are launching a new study to see how COVID-19 and lockdown are affecting people with bone, joint and mus

Updated on: June 01,2024

How lockdown impacts those with bone, joint and muscle pain

by University of East AngliaCredit: CC0 Public DomainUniversity of East Anglia researchers are launching a new study to see how COVID-19 and lockdown are affecting people with bone, joint and mus

Updated on:June 01,2024

New evidence that 'gout' strongly runs in the family

by University of NottinghamIt's historically known as 'the king of diseases and the disease of kings' and was long thought to be caused by an overindulgent lifestyle, but now scientis

Updated on: March 24,2024

New evidence that 'gout' strongly runs in the family

by University of NottinghamIt's historically known as 'the king of diseases and the disease of kings' and was long thought to be caused by an overindulgent lifestyle, but now scientis

Updated on:March 24,2024

Physical activity reduces cardiovascular risk in rheumatic patients

by FAPESPPeople with diseases such as rheumatoid arthritis and lupus are more likely to have heart attacks, angina, and strokes. A review of the scientific literature on the subject shows that re

Updated on: June 26,2024

Physical activity reduces cardiovascular risk in rheumatic patients

by FAPESPPeople with diseases such as rheumatoid arthritis and lupus are more likely to have heart attacks, angina, and strokes. A review of the scientific literature on the subject shows that re

Updated on:June 26,2024

Salivary gland ultrasonography improves Sjogren's diagnosis

The addition of salivary-gland ultrasonography to American-European Consensus Group classification criteria improves the accuracy of diagnosis of primary Sjögren's syndrome, according to a study p

Updated on: March 24,2024

Salivary gland ultrasonography improves Sjogren's diagnosis

The addition of salivary-gland ultrasonography to American-European Consensus Group classification criteria improves the accuracy of diagnosis of primary Sjögren's syndrome, according to a study p

Updated on:March 24,2024