T cells take the lead in controlling SARS-CoV-2 and reducing COVID-19 disease severity

by La Jolla Institute for ImmunologyA multi-layered, virus-specific immune response is important for controlling the virus during the acute phase of the infection and reducing COVID-19 disease se

Updated on: April 24,2024

T cells take the lead in controlling SARS-CoV-2 and reducing COVID-19 disease severity

by La Jolla Institute for ImmunologyA multi-layered, virus-specific immune response is important for controlling the virus during the acute phase of the infection and reducing COVID-19 disease se

Updated on:April 24,2024

COVID-19: The older you are, the more antibodies you have

by University of MontrealA colorized scanning electron micrograph of the SARS-CoV-2 virus. Credit: NIAIDWith the emergence of SARS-CoV-2 variants worldwide, the pandemic's spread is accelerat

Updated on: April 10,2024

COVID-19: The older you are, the more antibodies you have

by University of MontrealA colorized scanning electron micrograph of the SARS-CoV-2 virus. Credit: NIAIDWith the emergence of SARS-CoV-2 variants worldwide, the pandemic's spread is accelerat

Updated on:April 10,2024

New safety checklist aims to prevent side effects in patients with arthritis

by Line Rønn,Aarhus UniversityOverview of contraindications and warnings from EMA SmPC and FDA PI for biologic and targeted synthetic disease modifying antirheumatic drugs based on MedDRA system

Updated on: August 08,2024

New safety checklist aims to prevent side effects in patients with arthritis

by Line Rønn,Aarhus UniversityOverview of contraindications and warnings from EMA SmPC and FDA PI for biologic and targeted synthetic disease modifying antirheumatic drugs based on MedDRA system

Updated on:August 08,2024

Early drug intervention reduces risk of cardiovascular events in rheumatoid arthritis sufferers

by Rebecca Biason,University of TorontoCredit: CC0 Public DomainPeople who develop rheumatoid arthritis as older adults benefit from early and sustained use of a drug called Methotrexate (MTX),

Updated on: March 28,2024

Early drug intervention reduces risk of cardiovascular events in rheumatoid arthritis sufferers

by Rebecca Biason,University of TorontoCredit: CC0 Public DomainPeople who develop rheumatoid arthritis as older adults benefit from early and sustained use of a drug called Methotrexate (MTX),

Updated on:March 28,2024

Drug shows promise against arthritis common in people with psoriasis

by Steven Reinberg, Healthday ReporterNew medication improved skin condition, lessened swelling, study finds.(HealthDay)—A new drug called brodalumab appears to be effective in treating patients suffe

Updated on: March 24,2024

Drug shows promise against arthritis common in people with psoriasis

by Steven Reinberg, Healthday ReporterNew medication improved skin condition, lessened swelling, study finds.(HealthDay)—A new drug called brodalumab appears to be effective in treating patients suffe

Updated on:March 24,2024

Analysis of DNA reveals weapons used by our immune cells to fight tuberculosis

by Agency for Science, Technology and Research (A*STAR), SingaporeFig. 1: Histone acetylome-wide association study of TB. Credit: DOI: 10.1038/s41564-021-01049-wA study led by the Agency for Scie

Updated on: April 15,2024

Analysis of DNA reveals weapons used by our immune cells to fight tuberculosis

by Agency for Science, Technology and Research (A*STAR), SingaporeFig. 1: Histone acetylome-wide association study of TB. Credit: DOI: 10.1038/s41564-021-01049-wA study led by the Agency for Scie

Updated on:April 15,2024

Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

by Bob Yirka , Medical XpressPerturbation of X-inactivation in immune cells ofFtx−/−females.(A) Map of the X inactivation center showing the location ofXist(green) andFtx

Updated on: May 30,2024

Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

by Bob Yirka , Medical XpressPerturbation of X-inactivation in immune cells ofFtx−/−females.(A) Map of the X inactivation center showing the location ofXist(green) andFtx

Updated on:May 30,2024

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on: June 15,2024

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on:June 15,2024

Study compares hospitalized infection risk for biologics in RA

(HealthDay)—For patients with rheumatoid arthritis (RA) with prior biologic exposure, the risk of hospitalized infection is increased with etanercept, infliximab, and rituximab versus abatacept, accor

Updated on: April 08,2024

Study compares hospitalized infection risk for biologics in RA

(HealthDay)—For patients with rheumatoid arthritis (RA) with prior biologic exposure, the risk of hospitalized infection is increased with etanercept, infliximab, and rituximab versus abatacept, accor

Updated on:April 08,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on: May 07,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on:May 07,2024

Early signs of arthritis can be found in the mouth

by University of AdelaideThis is a hand afflicted by rheumatoid arthritis. Credit: The University of ManchesterA common gum disease may indicate a person's risk of developing rheumatoid arthr

Updated on: April 20,2024

Early signs of arthritis can be found in the mouth

by University of AdelaideThis is a hand afflicted by rheumatoid arthritis. Credit: The University of ManchesterA common gum disease may indicate a person's risk of developing rheumatoid arthr

Updated on:April 20,2024

New insight into when CAR T is effective against childhood leukemia

by University College LondonA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA 3.0Scientists an

Updated on: April 08,2024

New insight into when CAR T is effective against childhood leukemia

by University College LondonA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA 3.0Scientists an

Updated on:April 08,2024