New safety checklist aims to prevent side effects in patients with arthritis

by Line Rønn,Aarhus UniversityOverview of contraindications and warnings from EMA SmPC and FDA PI for biologic and targeted synthetic disease modifying antirheumatic drugs based on MedDRA system

Updated on: August 08,2024

New safety checklist aims to prevent side effects in patients with arthritis

by Line Rønn,Aarhus UniversityOverview of contraindications and warnings from EMA SmPC and FDA PI for biologic and targeted synthetic disease modifying antirheumatic drugs based on MedDRA system

Updated on:August 08,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on: May 07,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on:May 07,2024

Drug shows promise against arthritis common in people with psoriasis

by Steven Reinberg, Healthday ReporterNew medication improved skin condition, lessened swelling, study finds.(HealthDay)—A new drug called brodalumab appears to be effective in treating patients suffe

Updated on: March 24,2024

Drug shows promise against arthritis common in people with psoriasis

by Steven Reinberg, Healthday ReporterNew medication improved skin condition, lessened swelling, study finds.(HealthDay)—A new drug called brodalumab appears to be effective in treating patients suffe

Updated on:March 24,2024

Study compares hospitalized infection risk for biologics in RA

(HealthDay)—For patients with rheumatoid arthritis (RA) with prior biologic exposure, the risk of hospitalized infection is increased with etanercept, infliximab, and rituximab versus abatacept, accor

Updated on: April 08,2024

Study compares hospitalized infection risk for biologics in RA

(HealthDay)—For patients with rheumatoid arthritis (RA) with prior biologic exposure, the risk of hospitalized infection is increased with etanercept, infliximab, and rituximab versus abatacept, accor

Updated on:April 08,2024

New study points to a better way to ward off asthma triggers

by La Jolla Institute for ImmunologyLeft: Lung tissue of untreated mice. Right: Lung tissue of mice treated with antibodies blocking OX40L and CD30L. Credit: Dr. Gurupreet Sethi, La Jolla Institu

Updated on: May 05,2024

New study points to a better way to ward off asthma triggers

by La Jolla Institute for ImmunologyLeft: Lung tissue of untreated mice. Right: Lung tissue of mice treated with antibodies blocking OX40L and CD30L. Credit: Dr. Gurupreet Sethi, La Jolla Institu

Updated on:May 05,2024

Analysis of DNA reveals weapons used by our immune cells to fight tuberculosis

by Agency for Science, Technology and Research (A*STAR), SingaporeFig. 1: Histone acetylome-wide association study of TB. Credit: DOI: 10.1038/s41564-021-01049-wA study led by the Agency for Scie

Updated on: April 15,2024

Analysis of DNA reveals weapons used by our immune cells to fight tuberculosis

by Agency for Science, Technology and Research (A*STAR), SingaporeFig. 1: Histone acetylome-wide association study of TB. Credit: DOI: 10.1038/s41564-021-01049-wA study led by the Agency for Scie

Updated on:April 15,2024

COVID-19 vaccines produce antibody response in the nasal mucosa

by University of North Carolina Health CarePre-immunity and post-immunity SARS-CoV-2 virus-specific IgG and IgA antibody concentrations in NELF and serum. Antibody concentrations were reported as

Updated on: April 13,2024

COVID-19 vaccines produce antibody response in the nasal mucosa

by University of North Carolina Health CarePre-immunity and post-immunity SARS-CoV-2 virus-specific IgG and IgA antibody concentrations in NELF and serum. Antibody concentrations were reported as

Updated on:April 13,2024

How COVID-19 triggers massive inflammation

by Children's Hospital BostonSARS-CoV-2 (shown here in an electron microscopy image). Credit: National Institute of Allergy and Infectious Diseases, NIHA study led by researchers at Boston Ch

Updated on: April 13,2024

How COVID-19 triggers massive inflammation

by Children's Hospital BostonSARS-CoV-2 (shown here in an electron microscopy image). Credit: National Institute of Allergy and Infectious Diseases, NIHA study led by researchers at Boston Ch

Updated on:April 13,2024

New insight into when CAR T is effective against childhood leukemia

by University College LondonA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA 3.0Scientists an

Updated on: April 08,2024

New insight into when CAR T is effective against childhood leukemia

by University College LondonA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA 3.0Scientists an

Updated on:April 08,2024

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on: June 15,2024

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on:June 15,2024

Is it brain infection or cancer? A new rapid test could hold the answer

by Thomas Jefferson UniversityGram stain of meningococci from a culture showing Gram negative (pink) bacteria, often in pairs. Credit: public domainWhen patients present with neurologic symptoms

Updated on: April 16,2024

Is it brain infection or cancer? A new rapid test could hold the answer

by Thomas Jefferson UniversityGram stain of meningococci from a culture showing Gram negative (pink) bacteria, often in pairs. Credit: public domainWhen patients present with neurologic symptoms

Updated on:April 16,2024

How the immune system becomes blind to cancer cells

by University of FreiburgCancer cells become invisible to the body's immune response. Unhindered by T cells (green), they can continue to replicate. Scientists have now described an important

Updated on: April 16,2024

How the immune system becomes blind to cancer cells

by University of FreiburgCancer cells become invisible to the body's immune response. Unhindered by T cells (green), they can continue to replicate. Scientists have now described an important

Updated on:April 16,2024