Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on: May 07,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on:May 07,2024

Study: Why people with knee osteoarthritis experience different kinds of pain

by Boston University School of MedicineCredit: CC0 Public DomainOsteoarthritis is the most common form of arthritis worldwide, affecting more than 300 million people. It causes substantial pain,

Updated on: April 17,2024

Study: Why people with knee osteoarthritis experience different kinds of pain

by Boston University School of MedicineCredit: CC0 Public DomainOsteoarthritis is the most common form of arthritis worldwide, affecting more than 300 million people. It causes substantial pain,

Updated on:April 17,2024

Points to consider when using interferon assays

by European Alliance of Associations for Rheumatology (EULAR)Credit: Pixabay/CC0 Public DomainInterferons are type of protein called a cytokine. They have important roles in the immune system. Interfe

Updated on: May 26,2024

Points to consider when using interferon assays

by European Alliance of Associations for Rheumatology (EULAR)Credit: Pixabay/CC0 Public DomainInterferons are type of protein called a cytokine. They have important roles in the immune system. Interfe

Updated on:May 26,2024

How B cells are programmed early in life can impact long-term immune health

by Lund UniversityGraphical abstract. Credit:Immunity(2022). DOI: 10.1016/j.immuni.2022.08.018B cells and the antibodies they produce play an important role in our immune system, prot

Updated on: April 08,2024

How B cells are programmed early in life can impact long-term immune health

by Lund UniversityGraphical abstract. Credit:Immunity(2022). DOI: 10.1016/j.immuni.2022.08.018B cells and the antibodies they produce play an important role in our immune system, prot

Updated on:April 08,2024

Compound found to trigger innate immunity against viruses

by Bobbi Nodell,University of WashingtonCells under a microscope in a UW Medicine immunity lab. Credit: Dennis WiseResearch from UW Medicine and collaborators indicates that a drug-like molecule

Updated on: May 08,2024

Compound found to trigger innate immunity against viruses

by Bobbi Nodell,University of WashingtonCells under a microscope in a UW Medicine immunity lab. Credit: Dennis WiseResearch from UW Medicine and collaborators indicates that a drug-like molecule

Updated on:May 08,2024

Is it brain infection or cancer? A new rapid test could hold the answer

by Thomas Jefferson UniversityGram stain of meningococci from a culture showing Gram negative (pink) bacteria, often in pairs. Credit: public domainWhen patients present with neurologic symptoms

Updated on: April 16,2024

Is it brain infection or cancer? A new rapid test could hold the answer

by Thomas Jefferson UniversityGram stain of meningococci from a culture showing Gram negative (pink) bacteria, often in pairs. Credit: public domainWhen patients present with neurologic symptoms

Updated on:April 16,2024

A pan-cancer platform to help guide patient selection for personalized immunotherapy

by Vall d'Hebron Institute of OncologyGraphical Abstract. Credit:Med(2023). DOI: 10.1016/j.medj.2023.07.006Immunotherapy is a type of cancer treatment that boosts the immune syste

Updated on: May 05,2024

A pan-cancer platform to help guide patient selection for personalized immunotherapy

by Vall d'Hebron Institute of OncologyGraphical Abstract. Credit:Med(2023). DOI: 10.1016/j.medj.2023.07.006Immunotherapy is a type of cancer treatment that boosts the immune syste

Updated on:May 05,2024

New therapy shown to be effective in women with fibromyalgia and depression

by Universitat Oberta de CatalunyaCONSORT Diagram of participants flow in this randomized controlled trial. Credit:International Journal of Clinical and Health Psychology(2022). DOI: 10.10

Updated on: June 15,2024

New therapy shown to be effective in women with fibromyalgia and depression

by Universitat Oberta de CatalunyaCONSORT Diagram of participants flow in this randomized controlled trial. Credit:International Journal of Clinical and Health Psychology(2022). DOI: 10.10

Updated on:June 15,2024

Physical activity reduces cardiovascular risk in rheumatic patients

by FAPESPPeople with diseases such as rheumatoid arthritis and lupus are more likely to have heart attacks, angina, and strokes. A review of the scientific literature on the subject shows that re

Updated on: June 26,2024

Physical activity reduces cardiovascular risk in rheumatic patients

by FAPESPPeople with diseases such as rheumatoid arthritis and lupus are more likely to have heart attacks, angina, and strokes. A review of the scientific literature on the subject shows that re

Updated on:June 26,2024

Lithium may protect against cartilage decline in osteoarthritis

(HealthDay)—Lithium reduces catabolic events in interleukin-1 β (IL-1β)-treated human articular chondrocytes and protects against cartilage degradation in IL-1β-treated mouse knee joints, according to

Updated on: March 24,2024

Lithium may protect against cartilage decline in osteoarthritis

(HealthDay)—Lithium reduces catabolic events in interleukin-1 β (IL-1β)-treated human articular chondrocytes and protects against cartilage degradation in IL-1β-treated mouse knee joints, according to

Updated on:March 24,2024

New 3-D imaging analysis technique could lead to improved arthritis treatment

by University of CambridgeJoint space in hip, knee and ankle joints as analyzed by the JSM algorithm. Credit: Tom TurmezeiAn algorithm to monitor the joints of patients with arthritis, which coul

Updated on: May 29,2024

New 3-D imaging analysis technique could lead to improved arthritis treatment

by University of CambridgeJoint space in hip, knee and ankle joints as analyzed by the JSM algorithm. Credit: Tom TurmezeiAn algorithm to monitor the joints of patients with arthritis, which coul

Updated on:May 29,2024

Salivary gland ultrasonography improves Sjogren's diagnosis

The addition of salivary-gland ultrasonography to American-European Consensus Group classification criteria improves the accuracy of diagnosis of primary Sjögren's syndrome, according to a study p

Updated on: March 24,2024

Salivary gland ultrasonography improves Sjogren's diagnosis

The addition of salivary-gland ultrasonography to American-European Consensus Group classification criteria improves the accuracy of diagnosis of primary Sjögren's syndrome, according to a study p

Updated on:March 24,2024