Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

by Bob Yirka , Medical XpressPerturbation of X-inactivation in immune cells ofFtx−/−females.(A) Map of the X inactivation center showing the location ofXist(green) andFtx

Updated on: May 30,2024

Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

by Bob Yirka , Medical XpressPerturbation of X-inactivation in immune cells ofFtx−/−females.(A) Map of the X inactivation center showing the location ofXist(green) andFtx

Updated on:May 30,2024

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on: June 15,2024

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on:June 15,2024

A metabolic enzyme as a potential new target for cancer immune therapies

by German Cancer Research CenterCredit: Unsplash/CC0 Public DomainThe metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system. This wa

Updated on: May 07,2024

A metabolic enzyme as a potential new target for cancer immune therapies

by German Cancer Research CenterCredit: Unsplash/CC0 Public DomainThe metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system. This wa

Updated on:May 07,2024

How COVID-19 triggers massive inflammation

by Children's Hospital BostonSARS-CoV-2 (shown here in an electron microscopy image). Credit: National Institute of Allergy and Infectious Diseases, NIHA study led by researchers at Boston Ch

Updated on: April 13,2024

How COVID-19 triggers massive inflammation

by Children's Hospital BostonSARS-CoV-2 (shown here in an electron microscopy image). Credit: National Institute of Allergy and Infectious Diseases, NIHA study led by researchers at Boston Ch

Updated on:April 13,2024

Early signs of arthritis can be found in the mouth

by University of AdelaideThis is a hand afflicted by rheumatoid arthritis. Credit: The University of ManchesterA common gum disease may indicate a person's risk of developing rheumatoid arthr

Updated on: April 20,2024

Early signs of arthritis can be found in the mouth

by University of AdelaideThis is a hand afflicted by rheumatoid arthritis. Credit: The University of ManchesterA common gum disease may indicate a person's risk of developing rheumatoid arthr

Updated on:April 20,2024

Could oral contraceptives help ease rheumatoid arthritis?

by Steven Reinberg, Healthday ReporterOnly association was seen, and older women shouldn't take the pill to treat symptoms, experts say.(HealthDay)—Oral contraceptives—also known as birth control

Updated on: March 24,2024

Could oral contraceptives help ease rheumatoid arthritis?

by Steven Reinberg, Healthday ReporterOnly association was seen, and older women shouldn't take the pill to treat symptoms, experts say.(HealthDay)—Oral contraceptives—also known as birth control

Updated on:March 24,2024

Black patients with lupus have three times higher risk of stroke

by American College of RheumatologyCredit: CC0 Public DomainNew research reveals that, in the U.S., Black patients with lupus have a threefold higher risk of stroke and a 24-fold higher risk of i

Updated on: May 23,2024

Black patients with lupus have three times higher risk of stroke

by American College of RheumatologyCredit: CC0 Public DomainNew research reveals that, in the U.S., Black patients with lupus have a threefold higher risk of stroke and a 24-fold higher risk of i

Updated on:May 23,2024

How the immune system becomes blind to cancer cells

by University of FreiburgCancer cells become invisible to the body's immune response. Unhindered by T cells (green), they can continue to replicate. Scientists have now described an important

Updated on: April 16,2024

How the immune system becomes blind to cancer cells

by University of FreiburgCancer cells become invisible to the body's immune response. Unhindered by T cells (green), they can continue to replicate. Scientists have now described an important

Updated on:April 16,2024

CRISPR study reveals new immune system regulators

by Wellcome Trust Sanger InstituteCRISPR-associated protein Cas9 (white) from Staphylococcus aureus based on Protein Database ID 5AXW. Credit: Thomas Splettstoesser (Wikipedia, CC BY-SA 4.0)Scien

Updated on: April 13,2024

CRISPR study reveals new immune system regulators

by Wellcome Trust Sanger InstituteCRISPR-associated protein Cas9 (white) from Staphylococcus aureus based on Protein Database ID 5AXW. Credit: Thomas Splettstoesser (Wikipedia, CC BY-SA 4.0)Scien

Updated on:April 13,2024

Swimming short fibrous nasal drops achieve intraventricular administration

byScience China PressInspired by swimming fish and the microstructure of the nasal cavity, short-swimming fibrous nasal drops with the ability to transport drugs along the nasal mucosa were inno

Updated on: April 28,2024

Swimming short fibrous nasal drops achieve intraventricular administration

byScience China PressInspired by swimming fish and the microstructure of the nasal cavity, short-swimming fibrous nasal drops with the ability to transport drugs along the nasal mucosa were inno

Updated on:April 28,2024

New 3-D imaging analysis technique could lead to improved arthritis treatment

by University of CambridgeJoint space in hip, knee and ankle joints as analyzed by the JSM algorithm. Credit: Tom TurmezeiAn algorithm to monitor the joints of patients with arthritis, which coul

Updated on: May 29,2024

New 3-D imaging analysis technique could lead to improved arthritis treatment

by University of CambridgeJoint space in hip, knee and ankle joints as analyzed by the JSM algorithm. Credit: Tom TurmezeiAn algorithm to monitor the joints of patients with arthritis, which coul

Updated on:May 29,2024

Researchers unlock predictive biomarkers for common hip disorder

by University of MissouriBoxplots of significantly different median urine biomarker concentrations between the DDH cohort and healthy controls (P < 0.05). Median and the interquartile range ar

Updated on: May 19,2024

Researchers unlock predictive biomarkers for common hip disorder

by University of MissouriBoxplots of significantly different median urine biomarker concentrations between the DDH cohort and healthy controls (P < 0.05). Median and the interquartile range ar

Updated on:May 19,2024