A metabolic enzyme as a potential new target for cancer immune therapies

by German Cancer Research CenterCredit: Unsplash/CC0 Public DomainThe metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system. This wa

Updated on: May 07,2024

A metabolic enzyme as a potential new target for cancer immune therapies

by German Cancer Research CenterCredit: Unsplash/CC0 Public DomainThe metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system. This wa

Updated on:May 07,2024

New evidence that 'gout' strongly runs in the family

by University of NottinghamIt's historically known as 'the king of diseases and the disease of kings' and was long thought to be caused by an overindulgent lifestyle, but now scientis

Updated on: March 24,2024

New evidence that 'gout' strongly runs in the family

by University of NottinghamIt's historically known as 'the king of diseases and the disease of kings' and was long thought to be caused by an overindulgent lifestyle, but now scientis

Updated on:March 24,2024

Guidance for coronary patients with ASA/NSAID sensitivity

(HealthDay)—In patients with stable chronic ischemic heart disease (CIHD) and histories of nonsevere hypersensitivity reactions to acetylsalicylic acid (ASA)/nonsteroidal anti-inflammatory drugs (NSAI

Updated on: April 08,2024

Guidance for coronary patients with ASA/NSAID sensitivity

(HealthDay)—In patients with stable chronic ischemic heart disease (CIHD) and histories of nonsevere hypersensitivity reactions to acetylsalicylic acid (ASA)/nonsteroidal anti-inflammatory drugs (NSAI

Updated on:April 08,2024

Study investigates rates of adverse events for common rheumatoid arthritis drug

by Brigham and Women's HospitalCredit: CC0 Public DomainMethotrexate is a common drug with a long history; for the past 40 years, it's been used to treat a range of diseases. Today it is

Updated on: June 17,2024

Study investigates rates of adverse events for common rheumatoid arthritis drug

by Brigham and Women's HospitalCredit: CC0 Public DomainMethotrexate is a common drug with a long history; for the past 40 years, it's been used to treat a range of diseases. Today it is

Updated on:June 17,2024

New insight into when CAR T is effective against childhood leukemia

by University College LondonA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA 3.0Scientists an

Updated on: April 08,2024

New insight into when CAR T is effective against childhood leukemia

by University College LondonA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA 3.0Scientists an

Updated on:April 08,2024

Compound found to trigger innate immunity against viruses

by Bobbi Nodell,University of WashingtonCells under a microscope in a UW Medicine immunity lab. Credit: Dennis WiseResearch from UW Medicine and collaborators indicates that a drug-like molecule

Updated on: May 08,2024

Compound found to trigger innate immunity against viruses

by Bobbi Nodell,University of WashingtonCells under a microscope in a UW Medicine immunity lab. Credit: Dennis WiseResearch from UW Medicine and collaborators indicates that a drug-like molecule

Updated on:May 08,2024

Pretreatment with TNF inhibitors may improve outcomes of combination cancer immunotherapy

by Universidad de NavarraStudy proposes a new therapeutic approach against cancer that dissociates efficacy and toxicity in the use of combined immunotherapy in animal models. This clinical strat

Updated on: May 08,2024

Pretreatment with TNF inhibitors may improve outcomes of combination cancer immunotherapy

by Universidad de NavarraStudy proposes a new therapeutic approach against cancer that dissociates efficacy and toxicity in the use of combined immunotherapy in animal models. This clinical strat

Updated on:May 08,2024

Rheumatologist recommends patients receive pneumococcal vaccine

by UT Southwestern Medical CenterA pneumococcal vaccine is recommended for all patients with rheumatic disorders. Credit: UT Southwestern Medical CenterPatients with rheumatoid arthritis, lupus,

Updated on: June 01,2024

Rheumatologist recommends patients receive pneumococcal vaccine

by UT Southwestern Medical CenterA pneumococcal vaccine is recommended for all patients with rheumatic disorders. Credit: UT Southwestern Medical CenterPatients with rheumatoid arthritis, lupus,

Updated on:June 01,2024

COVID-19: The older you are, the more antibodies you have

by University of MontrealA colorized scanning electron micrograph of the SARS-CoV-2 virus. Credit: NIAIDWith the emergence of SARS-CoV-2 variants worldwide, the pandemic's spread is accelerat

Updated on: April 10,2024

COVID-19: The older you are, the more antibodies you have

by University of MontrealA colorized scanning electron micrograph of the SARS-CoV-2 virus. Credit: NIAIDWith the emergence of SARS-CoV-2 variants worldwide, the pandemic's spread is accelerat

Updated on:April 10,2024

CrAss viral content: When it's in your gut, it might be good for your health

by Osaka UniversityFig.1 Schematic illustration of the study design. Credit: Yoshihiko Tomofuji et al.,Annals of the Rheumatic DiseasesAutoimmune diseases are conditions in which the immune

Updated on: April 07,2024

CrAss viral content: When it's in your gut, it might be good for your health

by Osaka UniversityFig.1 Schematic illustration of the study design. Credit: Yoshihiko Tomofuji et al.,Annals of the Rheumatic DiseasesAutoimmune diseases are conditions in which the immune

Updated on:April 07,2024

The positive and negative role of LRH-1 during inflammation

by University of KonstanzDetection of immune cells using specific antibodies in tissue sections of the spleen of wild type animals (left panel) and mice with T cell-specific deletion of LRH-1 (ri

Updated on: April 16,2024

The positive and negative role of LRH-1 during inflammation

by University of KonstanzDetection of immune cells using specific antibodies in tissue sections of the spleen of wild type animals (left panel) and mice with T cell-specific deletion of LRH-1 (ri

Updated on:April 16,2024

Fatigue common even with early rheumatoid arthritis

(HealthDay)—Fatigue is prevalent and persistent in early rheumatoid arthritis (RA), according to a study published online Dec. 27 inRheumatology.Onosi Sylvia Ifesemen, M.B.B.S., from the Univers

Updated on: June 17,2024

Fatigue common even with early rheumatoid arthritis

(HealthDay)—Fatigue is prevalent and persistent in early rheumatoid arthritis (RA), according to a study published online Dec. 27 inRheumatology.Onosi Sylvia Ifesemen, M.B.B.S., from the Univers

Updated on:June 17,2024