Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on: May 07,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on:May 07,2024

B cells gone bad could be the culprit in rheumatoid arthritis

by Laurie Fickman,University of HoustonBiomolecular researcher Navin Varadarajan anticipates that his data will serve as a foundation for investigating multiple hypotheses on the roles of B cell

Updated on: April 08,2024

B cells gone bad could be the culprit in rheumatoid arthritis

by Laurie Fickman,University of HoustonBiomolecular researcher Navin Varadarajan anticipates that his data will serve as a foundation for investigating multiple hypotheses on the roles of B cell

Updated on:April 08,2024

AID/APOBECs among important factors in body's defence against SARS-CoV-2

by Johannes Angerer,Medical University of ViennaCredit: Unsplash/CC0 Public DomainTogether with their multifaceted action mechanisms, activation-induced cytidine deaminase (AID) and so-called AP

Updated on: April 08,2024

AID/APOBECs among important factors in body's defence against SARS-CoV-2

by Johannes Angerer,Medical University of ViennaCredit: Unsplash/CC0 Public DomainTogether with their multifaceted action mechanisms, activation-induced cytidine deaminase (AID) and so-called AP

Updated on:April 08,2024

The positive and negative role of LRH-1 during inflammation

by University of KonstanzDetection of immune cells using specific antibodies in tissue sections of the spleen of wild type animals (left panel) and mice with T cell-specific deletion of LRH-1 (ri

Updated on: April 16,2024

The positive and negative role of LRH-1 during inflammation

by University of KonstanzDetection of immune cells using specific antibodies in tissue sections of the spleen of wild type animals (left panel) and mice with T cell-specific deletion of LRH-1 (ri

Updated on:April 16,2024

MAIT cell activation may play a role in fatal outcomes among severe COVID-19 cases

by Public Library of ScienceProject design and overall conclusions of the St George’s, University of London and University of Oxford collaboration on immune parameters of ICU COVID-19 and severe

Updated on: April 20,2024

MAIT cell activation may play a role in fatal outcomes among severe COVID-19 cases

by Public Library of ScienceProject design and overall conclusions of the St George’s, University of London and University of Oxford collaboration on immune parameters of ICU COVID-19 and severe

Updated on:April 20,2024

Scientists discover possible target for treating and preventing osteoarthritis

by University of FloridaCredit: CC0 Public DomainWear and tear on joints can lead to inflammation, breakdown of cartilage and development of osteoarthritis. Scientists at UF Scripps Biomedical Re

Updated on: April 17,2024

Scientists discover possible target for treating and preventing osteoarthritis

by University of FloridaCredit: CC0 Public DomainWear and tear on joints can lead to inflammation, breakdown of cartilage and development of osteoarthritis. Scientists at UF Scripps Biomedical Re

Updated on:April 17,2024

Nrf2: The custodian regulating oxidative stress and immunity against acrylamide toxicity

by Tokyo University of ScienceGenetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice. Credit: Tokyo University of ScienceAcrylamide is a toxic chemical compound that affect

Updated on: April 20,2024

Nrf2: The custodian regulating oxidative stress and immunity against acrylamide toxicity

by Tokyo University of ScienceGenetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice. Credit: Tokyo University of ScienceAcrylamide is a toxic chemical compound that affect

Updated on:April 20,2024

Compound found to trigger innate immunity against viruses

by Bobbi Nodell,University of WashingtonCells under a microscope in a UW Medicine immunity lab. Credit: Dennis WiseResearch from UW Medicine and collaborators indicates that a drug-like molecule

Updated on: May 08,2024

Compound found to trigger innate immunity against viruses

by Bobbi Nodell,University of WashingtonCells under a microscope in a UW Medicine immunity lab. Credit: Dennis WiseResearch from UW Medicine and collaborators indicates that a drug-like molecule

Updated on:May 08,2024

Serum IL-35 levels tied to bone loss with rheumatoid arthritis

Serum interleukin (IL)-35 levels are associated with bone loss and may represent a novel therapeutic target for postmenopausal women with rheumatoid arthritis (RA), according to a study published onli

Updated on: June 06,2024

Serum IL-35 levels tied to bone loss with rheumatoid arthritis

Serum interleukin (IL)-35 levels are associated with bone loss and may represent a novel therapeutic target for postmenopausal women with rheumatoid arthritis (RA), according to a study published onli

Updated on:June 06,2024

Potential biomarkers identified for neuropsychiatric symptoms of lupus

by Laurie Fickman,University of HoustonCredit: CC0 Public DomainA globally renowned expert in autoimmune diseases and systemic lupus erythematosus (SLE) at the University of Houston has identifi

Updated on: June 06,2024

Potential biomarkers identified for neuropsychiatric symptoms of lupus

by Laurie Fickman,University of HoustonCredit: CC0 Public DomainA globally renowned expert in autoimmune diseases and systemic lupus erythematosus (SLE) at the University of Houston has identifi

Updated on:June 06,2024

CrAss viral content: When it's in your gut, it might be good for your health

by Osaka UniversityFig.1 Schematic illustration of the study design. Credit: Yoshihiko Tomofuji et al.,Annals of the Rheumatic DiseasesAutoimmune diseases are conditions in which the immune

Updated on: April 07,2024

CrAss viral content: When it's in your gut, it might be good for your health

by Osaka UniversityFig.1 Schematic illustration of the study design. Credit: Yoshihiko Tomofuji et al.,Annals of the Rheumatic DiseasesAutoimmune diseases are conditions in which the immune

Updated on:April 07,2024

Dietary fiber in the gut may help with skin allergies, says new study

by Monash UniversityCredit: Unsplash/CC0 Public DomainA Monash University study exploring the emerging gut-skin axis has found that microbial fermentation of dietary fiber in the gut can protect

Updated on: May 07,2024

Dietary fiber in the gut may help with skin allergies, says new study

by Monash UniversityCredit: Unsplash/CC0 Public DomainA Monash University study exploring the emerging gut-skin axis has found that microbial fermentation of dietary fiber in the gut can protect

Updated on:May 07,2024