Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on: June 15,2024

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on:June 15,2024

MAIT cell activation may play a role in fatal outcomes among severe COVID-19 cases

by Public Library of ScienceProject design and overall conclusions of the St George’s, University of London and University of Oxford collaboration on immune parameters of ICU COVID-19 and severe

Updated on: April 20,2024

MAIT cell activation may play a role in fatal outcomes among severe COVID-19 cases

by Public Library of ScienceProject design and overall conclusions of the St George’s, University of London and University of Oxford collaboration on immune parameters of ICU COVID-19 and severe

Updated on:April 20,2024

How B cells are programmed early in life can impact long-term immune health

by Lund UniversityGraphical abstract. Credit:Immunity(2022). DOI: 10.1016/j.immuni.2022.08.018B cells and the antibodies they produce play an important role in our immune system, prot

Updated on: April 08,2024

How B cells are programmed early in life can impact long-term immune health

by Lund UniversityGraphical abstract. Credit:Immunity(2022). DOI: 10.1016/j.immuni.2022.08.018B cells and the antibodies they produce play an important role in our immune system, prot

Updated on:April 08,2024

AID/APOBECs among important factors in body's defence against SARS-CoV-2

by Johannes Angerer,Medical University of ViennaCredit: Unsplash/CC0 Public DomainTogether with their multifaceted action mechanisms, activation-induced cytidine deaminase (AID) and so-called AP

Updated on: April 08,2024

AID/APOBECs among important factors in body's defence against SARS-CoV-2

by Johannes Angerer,Medical University of ViennaCredit: Unsplash/CC0 Public DomainTogether with their multifaceted action mechanisms, activation-induced cytidine deaminase (AID) and so-called AP

Updated on:April 08,2024

Compound found to trigger innate immunity against viruses

by Bobbi Nodell,University of WashingtonCells under a microscope in a UW Medicine immunity lab. Credit: Dennis WiseResearch from UW Medicine and collaborators indicates that a drug-like molecule

Updated on: May 08,2024

Compound found to trigger innate immunity against viruses

by Bobbi Nodell,University of WashingtonCells under a microscope in a UW Medicine immunity lab. Credit: Dennis WiseResearch from UW Medicine and collaborators indicates that a drug-like molecule

Updated on:May 08,2024

Researchers develop a handheld white blood cell tracker

by Kitta MacPherson,Rutgers UniversityStudy overview. (A) Image of CytoTracker device prototype. (B) An image of the CytoTracker microfluidic impedance cytometer. (C) Schematic of sensing mechan

Updated on: March 07,2024

Researchers develop a handheld white blood cell tracker

by Kitta MacPherson,Rutgers UniversityStudy overview. (A) Image of CytoTracker device prototype. (B) An image of the CytoTracker microfluidic impedance cytometer. (C) Schematic of sensing mechan

Updated on:March 07,2024

Mpox: Characterization of post-infectious immune response

by Pasteur InstituteHuman cells infected with MPXV (in green) among uninfected cells (nuclei in blue). Image taken with a confocal microscope. Credit: Mathieu Hubert and Olivier Schwartz, Institu

Updated on: April 20,2024

Mpox: Characterization of post-infectious immune response

by Pasteur InstituteHuman cells infected with MPXV (in green) among uninfected cells (nuclei in blue). Image taken with a confocal microscope. Credit: Mathieu Hubert and Olivier Schwartz, Institu

Updated on:April 20,2024

Can gut bacteria cause rheumatoid arthritis?

by Greg Glasgow,CU Anschutz Medical CampusCredit: Pixabay/CC0 Public DomainResearchers at the University of Colorado School of Medicine have discovered that a unique bacteria found in the gut co

Updated on: April 20,2024

Can gut bacteria cause rheumatoid arthritis?

by Greg Glasgow,CU Anschutz Medical CampusCredit: Pixabay/CC0 Public DomainResearchers at the University of Colorado School of Medicine have discovered that a unique bacteria found in the gut co

Updated on:April 20,2024

Building tolerance helps kids with wheat allergy

(HealthDay)—Giving trace amounts of wheat to children with wheat allergy shows promise in treating the allergy, according to new research.The researchers started with 46 wheat-allergicchildren,

Updated on: April 08,2024

Building tolerance helps kids with wheat allergy

(HealthDay)—Giving trace amounts of wheat to children with wheat allergy shows promise in treating the allergy, according to new research.The researchers started with 46 wheat-allergicchildren,

Updated on:April 08,2024

The importance of treatment goals in PSA

by European Alliance of Associations for Rheumatology (EULAR)Credit: Pixabay/CC0 Public DomainPsA is a type of inflammatory arthritis linked to psoriasis—a chronic condition affecting the skin and nai

Updated on: March 24,2024

The importance of treatment goals in PSA

by European Alliance of Associations for Rheumatology (EULAR)Credit: Pixabay/CC0 Public DomainPsA is a type of inflammatory arthritis linked to psoriasis—a chronic condition affecting the skin and nai

Updated on:March 24,2024

Scientists discover two cellular defects appear to drive disease in lupus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine and Brigham and Women's Hospital scientists have discovered a molecular defect that promotes the pathologic im

Updated on: July 11,2024

Scientists discover two cellular defects appear to drive disease in lupus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine and Brigham and Women's Hospital scientists have discovered a molecular defect that promotes the pathologic im

Updated on:July 11,2024

A leap forward in research on CAR T cell therapy

by University of HelsinkiCredit: CC0 Public DomainIn cancer immunotherapy, cells in the patient's own immune system are activated to attack cancer cells. CAR T cell therapy has been one of th

Updated on: April 09,2024

A leap forward in research on CAR T cell therapy

by University of HelsinkiCredit: CC0 Public DomainIn cancer immunotherapy, cells in the patient's own immune system are activated to attack cancer cells. CAR T cell therapy has been one of th

Updated on:April 09,2024