An AI strategy for identifying new immunotherapy targets

by Cleveland ClinicSlowest relaxation timescales estimated by unsupervised AI highlight concerted MHC–peptide dynamics and multiple peptide presentation modes. Credit:Briefings in Bioinform

Updated on: March 07,2024

An AI strategy for identifying new immunotherapy targets

by Cleveland ClinicSlowest relaxation timescales estimated by unsupervised AI highlight concerted MHC–peptide dynamics and multiple peptide presentation modes. Credit:Briefings in Bioinform

Updated on:March 07,2024

JAK signaling may be behind polymyalgia rheumatica

by Lori SolomonJanus tyrosine kinase (JAK) signaling may be involved in the pathogenesis of polymyalgia rheumatica (PMR), and tofacitinib may be an effective treatment, according to a pilot study publ

Updated on: April 16,2024

JAK signaling may be behind polymyalgia rheumatica

by Lori SolomonJanus tyrosine kinase (JAK) signaling may be involved in the pathogenesis of polymyalgia rheumatica (PMR), and tofacitinib may be an effective treatment, according to a pilot study publ

Updated on:April 16,2024

New insight into when CAR T is effective against childhood leukemia

by University College LondonA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA 3.0Scientists an

Updated on: April 08,2024

New insight into when CAR T is effective against childhood leukemia

by University College LondonA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA 3.0Scientists an

Updated on:April 08,2024

Analysis of DNA reveals weapons used by our immune cells to fight tuberculosis

by Agency for Science, Technology and Research (A*STAR), SingaporeFig. 1: Histone acetylome-wide association study of TB. Credit: DOI: 10.1038/s41564-021-01049-wA study led by the Agency for Scie

Updated on: April 15,2024

Analysis of DNA reveals weapons used by our immune cells to fight tuberculosis

by Agency for Science, Technology and Research (A*STAR), SingaporeFig. 1: Histone acetylome-wide association study of TB. Credit: DOI: 10.1038/s41564-021-01049-wA study led by the Agency for Scie

Updated on:April 15,2024

How salt can trigger inflammation in multiple sclerosis

by Bill Hathaway,Yale UniversityCredit: CC0 Public DomainResearchers at Yale have identified a high-salt environment as one of the contributing factors to the development of multiple sclerosis (

Updated on: April 16,2024

How salt can trigger inflammation in multiple sclerosis

by Bill Hathaway,Yale UniversityCredit: CC0 Public DomainResearchers at Yale have identified a high-salt environment as one of the contributing factors to the development of multiple sclerosis (

Updated on:April 16,2024

T-cell dysfunction increases cancer risk in obese populations, researchers say

bySaint Louis UniversityCD8+T cell dysfunction in the obese tumor microenvironment. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-47359-5Researchers at Saint Loui

Updated on: November 24,2024

T-cell dysfunction increases cancer risk in obese populations, researchers say

bySaint Louis UniversityCD8+T cell dysfunction in the obese tumor microenvironment. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-47359-5Researchers at Saint Loui

Updated on:November 24,2024

mRNA-1273 induces stronger response than BNT162b2 for immunosuppressed

For immunosuppressed patients, mRNA-1273 induces a stronger seroresponse than BNT162b2, according to a research letter published online May 16 inJAMA Network Open.Jonathan Mitchell, M.B.B.S., fr

Updated on: April 20,2024

mRNA-1273 induces stronger response than BNT162b2 for immunosuppressed

For immunosuppressed patients, mRNA-1273 induces a stronger seroresponse than BNT162b2, according to a research letter published online May 16 inJAMA Network Open.Jonathan Mitchell, M.B.B.S., fr

Updated on:April 20,2024

A pan-cancer platform to help guide patient selection for personalized immunotherapy

by Vall d'Hebron Institute of OncologyGraphical Abstract. Credit:Med(2023). DOI: 10.1016/j.medj.2023.07.006Immunotherapy is a type of cancer treatment that boosts the immune syste

Updated on: May 05,2024

A pan-cancer platform to help guide patient selection for personalized immunotherapy

by Vall d'Hebron Institute of OncologyGraphical Abstract. Credit:Med(2023). DOI: 10.1016/j.medj.2023.07.006Immunotherapy is a type of cancer treatment that boosts the immune syste

Updated on:May 05,2024

tRNA fragments are involved in poststroke immune reactions

by Goethe University Frankfurt am MainCredit: Pixabay/CC0 Public DomainSebastian Lobentanzer of Goethe University, Frankfurt, has been studying small RNA dynamics in various contexts using bioinf

Updated on: April 24,2024

tRNA fragments are involved in poststroke immune reactions

by Goethe University Frankfurt am MainCredit: Pixabay/CC0 Public DomainSebastian Lobentanzer of Goethe University, Frankfurt, has been studying small RNA dynamics in various contexts using bioinf

Updated on:April 24,2024

Study of T cells from COVID-19 convalescents guides vaccine strategies

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of the SARS-CoV-2-specific immune response kinetics. Memory T cells are maintained after recovery from COVID-19 with the

Updated on: April 10,2024

Study of T cells from COVID-19 convalescents guides vaccine strategies

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of the SARS-CoV-2-specific immune response kinetics. Memory T cells are maintained after recovery from COVID-19 with the

Updated on:April 10,2024

Physical activity reduces cardiovascular risk in rheumatic patients

by FAPESPPeople with diseases such as rheumatoid arthritis and lupus are more likely to have heart attacks, angina, and strokes. A review of the scientific literature on the subject shows that re

Updated on: June 26,2024

Physical activity reduces cardiovascular risk in rheumatic patients

by FAPESPPeople with diseases such as rheumatoid arthritis and lupus are more likely to have heart attacks, angina, and strokes. A review of the scientific literature on the subject shows that re

Updated on:June 26,2024

Early therapy for rheumatoid arthritis may slow heart disease

(HealthDay)—Disease-modifying antirheumatic drug (DMARD) therapy for rheumatoid arthritis (RA) treatment also cuts cardiovascular disease (CVD) risk, according to a study published online Aug. 28 in t

Updated on: May 29,2024

Early therapy for rheumatoid arthritis may slow heart disease

(HealthDay)—Disease-modifying antirheumatic drug (DMARD) therapy for rheumatoid arthritis (RA) treatment also cuts cardiovascular disease (CVD) risk, according to a study published online Aug. 28 in t

Updated on:May 29,2024