Immunology & Rheumatology

Covert tactics used by bacteria to trick human immune system

by McMaster UniversityBrian Coombes in his lab at McMaster University. Credit: McMaster UniversityMcMaster University researchers have found a new way bacteria evade the human immune system and p

Updated on: April 09,2024

Covert tactics used by bacteria to trick human immune system

by McMaster UniversityBrian Coombes in his lab at McMaster University. Credit: McMaster UniversityMcMaster University researchers have found a new way bacteria evade the human immune system and p

Updated on:April 09,2024

A pan-cancer platform to help guide patient selection for personalized immunotherapy

by Vall d'Hebron Institute of OncologyGraphical Abstract. Credit:Med(2023). DOI: 10.1016/j.medj.2023.07.006Immunotherapy is a type of cancer treatment that boosts the immune syste

Updated on: May 05,2024

A pan-cancer platform to help guide patient selection for personalized immunotherapy

by Vall d'Hebron Institute of OncologyGraphical Abstract. Credit:Med(2023). DOI: 10.1016/j.medj.2023.07.006Immunotherapy is a type of cancer treatment that boosts the immune syste

Updated on:May 05,2024

An AI strategy for identifying new immunotherapy targets

by Cleveland ClinicSlowest relaxation timescales estimated by unsupervised AI highlight concerted MHC–peptide dynamics and multiple peptide presentation modes. Credit:Briefings in Bioinform

Updated on: March 07,2024

An AI strategy for identifying new immunotherapy targets

by Cleveland ClinicSlowest relaxation timescales estimated by unsupervised AI highlight concerted MHC–peptide dynamics and multiple peptide presentation modes. Credit:Briefings in Bioinform

Updated on:March 07,2024

How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on: March 27,2024

How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on:March 27,2024

A metabolic enzyme as a potential new target for cancer immune therapies

by German Cancer Research CenterCredit: Unsplash/CC0 Public DomainThe metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system. This wa

Updated on: May 07,2024

A metabolic enzyme as a potential new target for cancer immune therapies

by German Cancer Research CenterCredit: Unsplash/CC0 Public DomainThe metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system. This wa

Updated on:May 07,2024

Physical activity reduces cardiovascular risk in rheumatic patients

by FAPESPPeople with diseases such as rheumatoid arthritis and lupus are more likely to have heart attacks, angina, and strokes. A review of the scientific literature on the subject shows that re

Updated on: June 26,2024

Physical activity reduces cardiovascular risk in rheumatic patients

by FAPESPPeople with diseases such as rheumatoid arthritis and lupus are more likely to have heart attacks, angina, and strokes. A review of the scientific literature on the subject shows that re

Updated on:June 26,2024

Monash researchers bringing hope to lupus patients

by Monash UniversityResearchers at Monash University are leading the world's largest study to describe lupus patients and disease characteristics, bringing treat-to-target options for lupus a

Updated on: March 24,2024

Monash researchers bringing hope to lupus patients

by Monash UniversityResearchers at Monash University are leading the world's largest study to describe lupus patients and disease characteristics, bringing treat-to-target options for lupus a

Updated on:March 24,2024

JAK signaling may be behind polymyalgia rheumatica

by Lori SolomonJanus tyrosine kinase (JAK) signaling may be involved in the pathogenesis of polymyalgia rheumatica (PMR), and tofacitinib may be an effective treatment, according to a pilot study publ

Updated on: April 16,2024

JAK signaling may be behind polymyalgia rheumatica

by Lori SolomonJanus tyrosine kinase (JAK) signaling may be involved in the pathogenesis of polymyalgia rheumatica (PMR), and tofacitinib may be an effective treatment, according to a pilot study publ

Updated on:April 16,2024

Severe reaction to pneumococcal vaccines in patients with CAPS

(HealthDay)—Pneumococcal vaccines can trigger a severe local and systemic inflammatory reaction in patients with cryopyrin-associated periodic syndromes (CAPS), according to a study published in the F

Updated on: April 17,2024

Severe reaction to pneumococcal vaccines in patients with CAPS

(HealthDay)—Pneumococcal vaccines can trigger a severe local and systemic inflammatory reaction in patients with cryopyrin-associated periodic syndromes (CAPS), according to a study published in the F

Updated on:April 17,2024

Study of T cells from COVID-19 convalescents guides vaccine strategies

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of the SARS-CoV-2-specific immune response kinetics. Memory T cells are maintained after recovery from COVID-19 with the

Updated on: April 10,2024

Study of T cells from COVID-19 convalescents guides vaccine strategies

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of the SARS-CoV-2-specific immune response kinetics. Memory T cells are maintained after recovery from COVID-19 with the

Updated on:April 10,2024

Bioluminescence technology reveals role of protein in immune response modulation

byUniversity of Western AustraliaCredit: Pixabay/CC0 Public DomainCutting-edge bioluminescence technology pioneered at The University of Western Australia has been used to uncover a potential ga