An AI strategy for identifying new immunotherapy targets

by Cleveland ClinicSlowest relaxation timescales estimated by unsupervised AI highlight concerted MHC–peptide dynamics and multiple peptide presentation modes. Credit:Briefings in Bioinform

Updated on: March 07,2024

An AI strategy for identifying new immunotherapy targets

by Cleveland ClinicSlowest relaxation timescales estimated by unsupervised AI highlight concerted MHC–peptide dynamics and multiple peptide presentation modes. Credit:Briefings in Bioinform

Updated on:March 07,2024

How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on: March 27,2024

How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on:March 27,2024

A new approach to study autoimmune diseases

by Indiana Biosciences Research InstituteVenn diagrams of risk genes expressed in the target tissues of the fourautoimmune diseases (type 1 diabetes, systemic lupus erythematosus, multiple sclerosis,

Updated on: March 25,2024

A new approach to study autoimmune diseases

by Indiana Biosciences Research InstituteVenn diagrams of risk genes expressed in the target tissues of the fourautoimmune diseases (type 1 diabetes, systemic lupus erythematosus, multiple sclerosis,

Updated on:March 25,2024

Guidance for coronary patients with ASA/NSAID sensitivity

(HealthDay)—In patients with stable chronic ischemic heart disease (CIHD) and histories of nonsevere hypersensitivity reactions to acetylsalicylic acid (ASA)/nonsteroidal anti-inflammatory drugs (NSAI

Updated on: April 08,2024

Guidance for coronary patients with ASA/NSAID sensitivity

(HealthDay)—In patients with stable chronic ischemic heart disease (CIHD) and histories of nonsevere hypersensitivity reactions to acetylsalicylic acid (ASA)/nonsteroidal anti-inflammatory drugs (NSAI

Updated on:April 08,2024

A metabolic enzyme as a potential new target for cancer immune therapies

by German Cancer Research CenterCredit: Unsplash/CC0 Public DomainThe metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system. This wa

Updated on: May 07,2024

A metabolic enzyme as a potential new target for cancer immune therapies

by German Cancer Research CenterCredit: Unsplash/CC0 Public DomainThe metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system. This wa

Updated on:May 07,2024

Dietary fiber in the gut may help with skin allergies, says new study

by Monash UniversityCredit: Unsplash/CC0 Public DomainA Monash University study exploring the emerging gut-skin axis has found that microbial fermentation of dietary fiber in the gut can protect

Updated on: May 07,2024

Dietary fiber in the gut may help with skin allergies, says new study

by Monash UniversityCredit: Unsplash/CC0 Public DomainA Monash University study exploring the emerging gut-skin axis has found that microbial fermentation of dietary fiber in the gut can protect

Updated on:May 07,2024

Study suggests parents' understanding of atopic dermatitis may influence child's diet

byAmerican College of Allergy, Asthma, and ImmunologyCredit: CC0 Public DomainParents of children with atopic dermatitis (AD, also called eczema) know that the allergic condition can mean a heig

Updated on: October 30,2024

Study suggests parents' understanding of atopic dermatitis may influence child's diet

byAmerican College of Allergy, Asthma, and ImmunologyCredit: CC0 Public DomainParents of children with atopic dermatitis (AD, also called eczema) know that the allergic condition can mean a heig

Updated on:October 30,2024

tRNA fragments are involved in poststroke immune reactions

by Goethe University Frankfurt am MainCredit: Pixabay/CC0 Public DomainSebastian Lobentanzer of Goethe University, Frankfurt, has been studying small RNA dynamics in various contexts using bioinf

Updated on: April 24,2024

tRNA fragments are involved in poststroke immune reactions

by Goethe University Frankfurt am MainCredit: Pixabay/CC0 Public DomainSebastian Lobentanzer of Goethe University, Frankfurt, has been studying small RNA dynamics in various contexts using bioinf

Updated on:April 24,2024

New insight into when CAR T is effective against childhood leukemia

by University College LondonA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA 3.0Scientists an

Updated on: April 08,2024

New insight into when CAR T is effective against childhood leukemia

by University College LondonA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA 3.0Scientists an

Updated on:April 08,2024

How salt can trigger inflammation in multiple sclerosis

by Bill Hathaway,Yale UniversityCredit: CC0 Public DomainResearchers at Yale have identified a high-salt environment as one of the contributing factors to the development of multiple sclerosis (

Updated on: April 16,2024

How salt can trigger inflammation in multiple sclerosis

by Bill Hathaway,Yale UniversityCredit: CC0 Public DomainResearchers at Yale have identified a high-salt environment as one of the contributing factors to the development of multiple sclerosis (

Updated on:April 16,2024

JAK signaling may be behind polymyalgia rheumatica

by Lori SolomonJanus tyrosine kinase (JAK) signaling may be involved in the pathogenesis of polymyalgia rheumatica (PMR), and tofacitinib may be an effective treatment, according to a pilot study publ

Updated on: April 16,2024

JAK signaling may be behind polymyalgia rheumatica

by Lori SolomonJanus tyrosine kinase (JAK) signaling may be involved in the pathogenesis of polymyalgia rheumatica (PMR), and tofacitinib may be an effective treatment, according to a pilot study publ

Updated on:April 16,2024

RA linked to restrictive, obstructive spirometry patterns

(HealthDay)—Rheumatoid arthritis (RA) is associated with restrictive and obstructive spirometry patterns, with the strongest associations seen for severe patterns, according to a study published onlin

Updated on: June 01,2024

RA linked to restrictive, obstructive spirometry patterns

(HealthDay)—Rheumatoid arthritis (RA) is associated with restrictive and obstructive spirometry patterns, with the strongest associations seen for severe patterns, according to a study published onlin

Updated on:June 01,2024