A pan-cancer platform to help guide patient selection for personalized immunotherapy

by Vall d'Hebron Institute of OncologyGraphical Abstract. Credit:Med(2023). DOI: 10.1016/j.medj.2023.07.006Immunotherapy is a type of cancer treatment that boosts the immune syste

Updated on: May 05,2024

A pan-cancer platform to help guide patient selection for personalized immunotherapy

by Vall d'Hebron Institute of OncologyGraphical Abstract. Credit:Med(2023). DOI: 10.1016/j.medj.2023.07.006Immunotherapy is a type of cancer treatment that boosts the immune syste

Updated on:May 05,2024

Study compares hospitalized infection risk for biologics in RA

(HealthDay)—For patients with rheumatoid arthritis (RA) with prior biologic exposure, the risk of hospitalized infection is increased with etanercept, infliximab, and rituximab versus abatacept, accor

Updated on: April 08,2024

Study compares hospitalized infection risk for biologics in RA

(HealthDay)—For patients with rheumatoid arthritis (RA) with prior biologic exposure, the risk of hospitalized infection is increased with etanercept, infliximab, and rituximab versus abatacept, accor

Updated on:April 08,2024

Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

by Bob Yirka , Medical XpressPerturbation of X-inactivation in immune cells ofFtx−/−females.(A) Map of the X inactivation center showing the location ofXist(green) andFtx

Updated on: May 30,2024

Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

by Bob Yirka , Medical XpressPerturbation of X-inactivation in immune cells ofFtx−/−females.(A) Map of the X inactivation center showing the location ofXist(green) andFtx

Updated on:May 30,2024

Scientists discover two cellular defects appear to drive disease in lupus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine and Brigham and Women's Hospital scientists have discovered a molecular defect that promotes the pathologic im

Updated on: July 11,2024

Scientists discover two cellular defects appear to drive disease in lupus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine and Brigham and Women's Hospital scientists have discovered a molecular defect that promotes the pathologic im

Updated on:July 11,2024

Serum IL-35 levels tied to bone loss with rheumatoid arthritis

Serum interleukin (IL)-35 levels are associated with bone loss and may represent a novel therapeutic target for postmenopausal women with rheumatoid arthritis (RA), according to a study published onli

Updated on: June 06,2024

Serum IL-35 levels tied to bone loss with rheumatoid arthritis

Serum interleukin (IL)-35 levels are associated with bone loss and may represent a novel therapeutic target for postmenopausal women with rheumatoid arthritis (RA), according to a study published onli

Updated on:June 06,2024

Early therapy for rheumatoid arthritis may slow heart disease

(HealthDay)—Disease-modifying antirheumatic drug (DMARD) therapy for rheumatoid arthritis (RA) treatment also cuts cardiovascular disease (CVD) risk, according to a study published online Aug. 28 in t

Updated on: May 29,2024

Early therapy for rheumatoid arthritis may slow heart disease

(HealthDay)—Disease-modifying antirheumatic drug (DMARD) therapy for rheumatoid arthritis (RA) treatment also cuts cardiovascular disease (CVD) risk, according to a study published online Aug. 28 in t

Updated on:May 29,2024

Building tolerance helps kids with wheat allergy

(HealthDay)—Giving trace amounts of wheat to children with wheat allergy shows promise in treating the allergy, according to new research.The researchers started with 46 wheat-allergicchildren,

Updated on: April 08,2024

Building tolerance helps kids with wheat allergy

(HealthDay)—Giving trace amounts of wheat to children with wheat allergy shows promise in treating the allergy, according to new research.The researchers started with 46 wheat-allergicchildren,

Updated on:April 08,2024

Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on: June 06,2024

Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on:June 06,2024

X chromosome gene may explain why women are more prone to autoimmune diseases

by Alice Walton,University of California, Los Angeles(A) Using the high-throughput sequencing approach, sexually biased X chromosome genes in CD4+T cells were determined for C57BL/6J naive

Updated on: May 05,2024

X chromosome gene may explain why women are more prone to autoimmune diseases

by Alice Walton,University of California, Los Angeles(A) Using the high-throughput sequencing approach, sexually biased X chromosome genes in CD4+T cells were determined for C57BL/6J naive

Updated on:May 05,2024

Antibiotic usage associated with increased risk of rheumatoid arthritis

by Andrew Cain,Keele UniversityCredit: CC0 Public DomainA new study has provided evidence that antibiotic usage is associated with an increased risk of developing rheumatoid arthritis.Researcher

Updated on: March 24,2024

Antibiotic usage associated with increased risk of rheumatoid arthritis

by Andrew Cain,Keele UniversityCredit: CC0 Public DomainA new study has provided evidence that antibiotic usage is associated with an increased risk of developing rheumatoid arthritis.Researcher

Updated on:March 24,2024

tRNA fragments are involved in poststroke immune reactions

by Goethe University Frankfurt am MainCredit: Pixabay/CC0 Public DomainSebastian Lobentanzer of Goethe University, Frankfurt, has been studying small RNA dynamics in various contexts using bioinf

Updated on: April 24,2024

tRNA fragments are involved in poststroke immune reactions

by Goethe University Frankfurt am MainCredit: Pixabay/CC0 Public DomainSebastian Lobentanzer of Goethe University, Frankfurt, has been studying small RNA dynamics in various contexts using bioinf

Updated on:April 24,2024

'JEDI' technology awakens new understanding of how immune system works

by The Mount Sinai Hospital3D rendering of a T cell. Credit: CC BY 3.0, Blausen.com staff. "Blausen gallery 2014". Wikiversity Journal of Medicine. DOI:10.15347/wjm/2014.010. ISSN 20018

Updated on: April 16,2024

'JEDI' technology awakens new understanding of how immune system works

by The Mount Sinai Hospital3D rendering of a T cell. Credit: CC BY 3.0, Blausen.com staff. "Blausen gallery 2014". Wikiversity Journal of Medicine. DOI:10.15347/wjm/2014.010. ISSN 20018

Updated on:April 16,2024