A metabolic enzyme as a potential new target for cancer immune therapies

by German Cancer Research CenterCredit: Unsplash/CC0 Public DomainThe metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system. This wa

Updated on: May 07,2024

A metabolic enzyme as a potential new target for cancer immune therapies

by German Cancer Research CenterCredit: Unsplash/CC0 Public DomainThe metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system. This wa

Updated on:May 07,2024

Early therapy for rheumatoid arthritis may slow heart disease

(HealthDay)—Disease-modifying antirheumatic drug (DMARD) therapy for rheumatoid arthritis (RA) treatment also cuts cardiovascular disease (CVD) risk, according to a study published online Aug. 28 in t

Updated on: May 29,2024

Early therapy for rheumatoid arthritis may slow heart disease

(HealthDay)—Disease-modifying antirheumatic drug (DMARD) therapy for rheumatoid arthritis (RA) treatment also cuts cardiovascular disease (CVD) risk, according to a study published online Aug. 28 in t

Updated on:May 29,2024

Rheumatologist recommends patients receive pneumococcal vaccine

by UT Southwestern Medical CenterA pneumococcal vaccine is recommended for all patients with rheumatic disorders. Credit: UT Southwestern Medical CenterPatients with rheumatoid arthritis, lupus,

Updated on: June 01,2024

Rheumatologist recommends patients receive pneumococcal vaccine

by UT Southwestern Medical CenterA pneumococcal vaccine is recommended for all patients with rheumatic disorders. Credit: UT Southwestern Medical CenterPatients with rheumatoid arthritis, lupus,

Updated on:June 01,2024

The role of T-cells in SARS-CoV-2 virus defense

by Universitaet TübingenA colorized scanning electron micrograph of the SARS-CoV-2 virus. Credit: NIAIDOur immune system can efficiently fend off viral diseases. T-cells can directly destroy viru

Updated on: May 05,2024

The role of T-cells in SARS-CoV-2 virus defense

by Universitaet TübingenA colorized scanning electron micrograph of the SARS-CoV-2 virus. Credit: NIAIDOur immune system can efficiently fend off viral diseases. T-cells can directly destroy viru

Updated on:May 05,2024

Study finds half of patients with low-grade proteinuria develop treatable lupus nephritis within two years

by American College of RheumatologyCredit: Short- and Long-Term Progression of Kidney Involvement in Systemic Lupus Erythematosus Patients with Low-Grade Proteinuria (2022) https://acrabstracts.o

Updated on: May 08,2024

Study finds half of patients with low-grade proteinuria develop treatable lupus nephritis within two years

by American College of RheumatologyCredit: Short- and Long-Term Progression of Kidney Involvement in Systemic Lupus Erythematosus Patients with Low-Grade Proteinuria (2022) https://acrabstracts.o

Updated on:May 08,2024

T-cell dysfunction increases cancer risk in obese populations, researchers say

bySaint Louis UniversityCD8+T cell dysfunction in the obese tumor microenvironment. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-47359-5Researchers at Saint Loui

Updated on: November 24,2024

T-cell dysfunction increases cancer risk in obese populations, researchers say

bySaint Louis UniversityCD8+T cell dysfunction in the obese tumor microenvironment. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-47359-5Researchers at Saint Loui

Updated on:November 24,2024

mRNA-1273 induces stronger response than BNT162b2 for immunosuppressed

For immunosuppressed patients, mRNA-1273 induces a stronger seroresponse than BNT162b2, according to a research letter published online May 16 inJAMA Network Open.Jonathan Mitchell, M.B.B.S., fr

Updated on: April 20,2024

mRNA-1273 induces stronger response than BNT162b2 for immunosuppressed

For immunosuppressed patients, mRNA-1273 induces a stronger seroresponse than BNT162b2, according to a research letter published online May 16 inJAMA Network Open.Jonathan Mitchell, M.B.B.S., fr

Updated on:April 20,2024

Is it brain infection or cancer? A new rapid test could hold the answer

by Thomas Jefferson UniversityGram stain of meningococci from a culture showing Gram negative (pink) bacteria, often in pairs. Credit: public domainWhen patients present with neurologic symptoms

Updated on: April 16,2024

Is it brain infection or cancer? A new rapid test could hold the answer

by Thomas Jefferson UniversityGram stain of meningococci from a culture showing Gram negative (pink) bacteria, often in pairs. Credit: public domainWhen patients present with neurologic symptoms

Updated on:April 16,2024

Pretreatment with TNF inhibitors may improve outcomes of combination cancer immunotherapy

by Universidad de NavarraStudy proposes a new therapeutic approach against cancer that dissociates efficacy and toxicity in the use of combined immunotherapy in animal models. This clinical strat

Updated on: May 08,2024

Pretreatment with TNF inhibitors may improve outcomes of combination cancer immunotherapy

by Universidad de NavarraStudy proposes a new therapeutic approach against cancer that dissociates efficacy and toxicity in the use of combined immunotherapy in animal models. This clinical strat

Updated on:May 08,2024

Gene variant tied to risk for interstitial lung disease in RA

(HealthDay)—For patients with rheumatoid arthritis (RA), theMUC5Bvariant is associated with an increased risk for RA-associated interstitial lung disease (ILD), according to a study publis

Updated on: June 26,2024

Gene variant tied to risk for interstitial lung disease in RA

(HealthDay)—For patients with rheumatoid arthritis (RA), theMUC5Bvariant is associated with an increased risk for RA-associated interstitial lung disease (ILD), according to a study publis

Updated on:June 26,2024

How B cells fight the COVID-19 virus

by Sarah C.p. Williams,Broad Institute of MIT and HarvardResearchers discovered a new antibody (light blue) that neutralizes the COVID-19 virus, by binding to the virus’s spike protein (grey) an

Updated on: April 08,2024

How B cells fight the COVID-19 virus

by Sarah C.p. Williams,Broad Institute of MIT and HarvardResearchers discovered a new antibody (light blue) that neutralizes the COVID-19 virus, by binding to the virus’s spike protein (grey) an

Updated on:April 08,2024

Serum IL-35 levels tied to bone loss with rheumatoid arthritis

Serum interleukin (IL)-35 levels are associated with bone loss and may represent a novel therapeutic target for postmenopausal women with rheumatoid arthritis (RA), according to a study published onli

Updated on: June 06,2024

Serum IL-35 levels tied to bone loss with rheumatoid arthritis

Serum interleukin (IL)-35 levels are associated with bone loss and may represent a novel therapeutic target for postmenopausal women with rheumatoid arthritis (RA), according to a study published onli

Updated on:June 06,2024