How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on: March 27,2024

How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on:March 27,2024

Points to consider when using interferon assays

by European Alliance of Associations for Rheumatology (EULAR)Credit: Pixabay/CC0 Public DomainInterferons are type of protein called a cytokine. They have important roles in the immune system. Interfe

Updated on: May 26,2024

Points to consider when using interferon assays

by European Alliance of Associations for Rheumatology (EULAR)Credit: Pixabay/CC0 Public DomainInterferons are type of protein called a cytokine. They have important roles in the immune system. Interfe

Updated on:May 26,2024

JAK signaling may be behind polymyalgia rheumatica

by Lori SolomonJanus tyrosine kinase (JAK) signaling may be involved in the pathogenesis of polymyalgia rheumatica (PMR), and tofacitinib may be an effective treatment, according to a pilot study publ

Updated on: April 16,2024

JAK signaling may be behind polymyalgia rheumatica

by Lori SolomonJanus tyrosine kinase (JAK) signaling may be involved in the pathogenesis of polymyalgia rheumatica (PMR), and tofacitinib may be an effective treatment, according to a pilot study publ

Updated on:April 16,2024

RA linked to restrictive, obstructive spirometry patterns

(HealthDay)—Rheumatoid arthritis (RA) is associated with restrictive and obstructive spirometry patterns, with the strongest associations seen for severe patterns, according to a study published onlin

Updated on: June 01,2024

RA linked to restrictive, obstructive spirometry patterns

(HealthDay)—Rheumatoid arthritis (RA) is associated with restrictive and obstructive spirometry patterns, with the strongest associations seen for severe patterns, according to a study published onlin

Updated on:June 01,2024

Novel study identifies key molecular players in rheumatoid arthritis

by University of California - San DiegoAn x-ray depicts a hand fully affected by rheumatoid arthritis, which is characterized by swollen, painful joints, most commonly involving the wrists and ha

Updated on: June 15,2024

Novel study identifies key molecular players in rheumatoid arthritis

by University of California - San DiegoAn x-ray depicts a hand fully affected by rheumatoid arthritis, which is characterized by swollen, painful joints, most commonly involving the wrists and ha

Updated on:June 15,2024

mRNA-1273 induces stronger response than BNT162b2 for immunosuppressed

For immunosuppressed patients, mRNA-1273 induces a stronger seroresponse than BNT162b2, according to a research letter published online May 16 inJAMA Network Open.Jonathan Mitchell, M.B.B.S., fr

Updated on: April 20,2024

mRNA-1273 induces stronger response than BNT162b2 for immunosuppressed

For immunosuppressed patients, mRNA-1273 induces a stronger seroresponse than BNT162b2, according to a research letter published online May 16 inJAMA Network Open.Jonathan Mitchell, M.B.B.S., fr

Updated on:April 20,2024

Serum IL-35 levels tied to bone loss with rheumatoid arthritis

Serum interleukin (IL)-35 levels are associated with bone loss and may represent a novel therapeutic target for postmenopausal women with rheumatoid arthritis (RA), according to a study published onli

Updated on: June 06,2024

Serum IL-35 levels tied to bone loss with rheumatoid arthritis

Serum interleukin (IL)-35 levels are associated with bone loss and may represent a novel therapeutic target for postmenopausal women with rheumatoid arthritis (RA), according to a study published onli

Updated on:June 06,2024

Depemokimab cuts exacerbation rate in eosinophilic asthma

by Elana GotkineFor patients with severe asthma with an eosinophilic phenotype, depemokimab reduces the annualized rate of exacerbations, according to a studypublishedonline Sept. 9 in the

Updated on: October 01,2024

Depemokimab cuts exacerbation rate in eosinophilic asthma

by Elana GotkineFor patients with severe asthma with an eosinophilic phenotype, depemokimab reduces the annualized rate of exacerbations, according to a studypublishedonline Sept. 9 in the

Updated on:October 01,2024

Early therapy for rheumatoid arthritis may slow heart disease

(HealthDay)—Disease-modifying antirheumatic drug (DMARD) therapy for rheumatoid arthritis (RA) treatment also cuts cardiovascular disease (CVD) risk, according to a study published online Aug. 28 in t

Updated on: May 29,2024

Early therapy for rheumatoid arthritis may slow heart disease

(HealthDay)—Disease-modifying antirheumatic drug (DMARD) therapy for rheumatoid arthritis (RA) treatment also cuts cardiovascular disease (CVD) risk, according to a study published online Aug. 28 in t

Updated on:May 29,2024

Fecal microbiota transplantation for active peripheral psoriatic arthritis shows no advantage

by European Alliance of Associations for RheumatologyCredit: CC0 Public DomainIn this proof-of-concept study, Maja Skov Kragsnaes and colleagues evaluated efficacy and safety of FMT in people with pso

Updated on: June 17,2024

Fecal microbiota transplantation for active peripheral psoriatic arthritis shows no advantage

by European Alliance of Associations for RheumatologyCredit: CC0 Public DomainIn this proof-of-concept study, Maja Skov Kragsnaes and colleagues evaluated efficacy and safety of FMT in people with pso

Updated on:June 17,2024

Paradigm shift: How a risk-based program is changing health care use and outcomes for children with high-risk asthma

by Le Bonheur Children's HospitalCredit: Pixabay/CC0 Public DomainLe Bonheur Children's Hospital's risk-based innovation program Changing High-Risk Asthma in Memphis through Partnership (C

Updated on: March 07,2024

Paradigm shift: How a risk-based program is changing health care use and outcomes for children with high-risk asthma

by Le Bonheur Children's HospitalCredit: Pixabay/CC0 Public DomainLe Bonheur Children's Hospital's risk-based innovation program Changing High-Risk Asthma in Memphis through Partnership (C

Updated on:March 07,2024

T cells alone are sufficient to establish and maintain HIV infection in the brain

by University of North Carolina Health CareScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDA new study by Unive

Updated on: May 07,2024

T cells alone are sufficient to establish and maintain HIV infection in the brain

by University of North Carolina Health CareScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDA new study by Unive

Updated on:May 07,2024