Lymph node-like biomaterial scaffold for augmenting CAR-T cell therapy

byScience China PressOn the top, the schematic illustration shows the structure of scaffold, the seeding and proliferation of CAR-T cells within the scaffold after intratumor injection. On the b

Updated on: March 27,2024

Lymph node-like biomaterial scaffold for augmenting CAR-T cell therapy

byScience China PressOn the top, the schematic illustration shows the structure of scaffold, the seeding and proliferation of CAR-T cells within the scaffold after intratumor injection. On the b

Updated on:March 27,2024

Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on: June 06,2024

Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on:June 06,2024

Research identifies protein that protects healthy joints from osteoarthritis

by University of DelawareThe blue area is the cell nucleus, the white area is F-actin, the structural scaffolding of the cells. Researchers discovered adseverin regulates the amount of F-actin in

Updated on: May 26,2024

Research identifies protein that protects healthy joints from osteoarthritis

by University of DelawareThe blue area is the cell nucleus, the white area is F-actin, the structural scaffolding of the cells. Researchers discovered adseverin regulates the amount of F-actin in

Updated on:May 26,2024

Scientists find genetic link between sugary drinks and gout

by University of Otago(Medical Xpress)—University of Otago and Auckland scientists have for the first time discovered a human gene variant that can "turn bad" when affected by sugary dr

Updated on: March 24,2024

Scientists find genetic link between sugary drinks and gout

by University of Otago(Medical Xpress)—University of Otago and Auckland scientists have for the first time discovered a human gene variant that can "turn bad" when affected by sugary dr

Updated on:March 24,2024

Promising target for CAR T cells helps cancer trick the immune system

by St. Jude Children's Research HospitalGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101297Findings from St. Jude Children's Research Hospi

Updated on: April 09,2024

Promising target for CAR T cells helps cancer trick the immune system

by St. Jude Children's Research HospitalGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101297Findings from St. Jude Children's Research Hospi

Updated on:April 09,2024

Study examines care received by patients with knee osteoarthritis

by WileyCredit: CC0 Public DomainNew research reveals that only a minority of U.S. Medicare beneficiaries with knee osteoarthritis in 2005-2010 used non-surgical care such as physical therapy and

Updated on: May 19,2024

Study examines care received by patients with knee osteoarthritis

by WileyCredit: CC0 Public DomainNew research reveals that only a minority of U.S. Medicare beneficiaries with knee osteoarthritis in 2005-2010 used non-surgical care such as physical therapy and

Updated on:May 19,2024

Some cases of long COVID-19 may be caused by an abnormally suppressed immune system

by University of California, Los AngelesCredit: Unsplash/CC0 Public DomainA UCLA-led team of researchers studying the effect of the monoclonal antibody Leronlimab on long COVID-19 may have found

Updated on: May 05,2024

Some cases of long COVID-19 may be caused by an abnormally suppressed immune system

by University of California, Los AngelesCredit: Unsplash/CC0 Public DomainA UCLA-led team of researchers studying the effect of the monoclonal antibody Leronlimab on long COVID-19 may have found

Updated on:May 05,2024

Study reveals new role for inflammatory protein in fat tissue

byKarolinska InstitutetMicroscope image of fat cells. Credit: Kaisa HofwimmerA new studypublishedinNature Communicationsshows that the inflammatory protein IL-1β has an i

Updated on: October 30,2024

Study reveals new role for inflammatory protein in fat tissue

byKarolinska InstitutetMicroscope image of fat cells. Credit: Kaisa HofwimmerA new studypublishedinNature Communicationsshows that the inflammatory protein IL-1β has an i

Updated on:October 30,2024

Unique immune response found in patients who experience inflammatory arthritis as side effect of cancer therapies

by Brigham and Women's HospitalMultiplexed immunofluorescence of synovial tissue. Multiplexed immunofluorescence images showing an example of a Ki67+PD-1+synovial CD8 T cell (white arro

Updated on: July 03,2024

Unique immune response found in patients who experience inflammatory arthritis as side effect of cancer therapies

by Brigham and Women's HospitalMultiplexed immunofluorescence of synovial tissue. Multiplexed immunofluorescence images showing an example of a Ki67+PD-1+synovial CD8 T cell (white arro

Updated on:July 03,2024

Trimethoprim-induced aseptic meningitis described

(HealthDay)—Drug-induced aseptic meningitis following trimethoprim use has been described in a research letter published online Nov. 20 in theInternational Journal of Rheumatic Diseases.Gayathir

Updated on: March 24,2024

Trimethoprim-induced aseptic meningitis described

(HealthDay)—Drug-induced aseptic meningitis following trimethoprim use has been described in a research letter published online Nov. 20 in theInternational Journal of Rheumatic Diseases.Gayathir

Updated on:March 24,2024

Potentially predictive humoral immune response markers in COVID-19 patients

by Massachusetts General HospitalCredit: CC0 Public DomainGalit Alter, Ph.D., Group Leader at the Ragon Institute of MGH, MIT and Harvard and Professor of Medicine at Harvard Medical School, and

Updated on: April 10,2024

Potentially predictive humoral immune response markers in COVID-19 patients

by Massachusetts General HospitalCredit: CC0 Public DomainGalit Alter, Ph.D., Group Leader at the Ragon Institute of MGH, MIT and Harvard and Professor of Medicine at Harvard Medical School, and

Updated on:April 10,2024

Paradigm shift: How a risk-based program is changing health care use and outcomes for children with high-risk asthma

by Le Bonheur Children's HospitalCredit: Pixabay/CC0 Public DomainLe Bonheur Children's Hospital's risk-based innovation program Changing High-Risk Asthma in Memphis through Partnership (C

Updated on: March 07,2024

Paradigm shift: How a risk-based program is changing health care use and outcomes for children with high-risk asthma

by Le Bonheur Children's HospitalCredit: Pixabay/CC0 Public DomainLe Bonheur Children's Hospital's risk-based innovation program Changing High-Risk Asthma in Memphis through Partnership (C

Updated on:March 07,2024