T-cell dysfunction increases cancer risk in obese populations, researchers say

bySaint Louis UniversityCD8+T cell dysfunction in the obese tumor microenvironment. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-47359-5Researchers at Saint Loui

Updated on: November 24,2024

T-cell dysfunction increases cancer risk in obese populations, researchers say

bySaint Louis UniversityCD8+T cell dysfunction in the obese tumor microenvironment. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-47359-5Researchers at Saint Loui

Updated on:November 24,2024

Research identifies protein that protects healthy joints from osteoarthritis

by University of DelawareThe blue area is the cell nucleus, the white area is F-actin, the structural scaffolding of the cells. Researchers discovered adseverin regulates the amount of F-actin in

Updated on: May 26,2024

Research identifies protein that protects healthy joints from osteoarthritis

by University of DelawareThe blue area is the cell nucleus, the white area is F-actin, the structural scaffolding of the cells. Researchers discovered adseverin regulates the amount of F-actin in

Updated on:May 26,2024

How B cells fight the COVID-19 virus

by Sarah C.p. Williams,Broad Institute of MIT and HarvardResearchers discovered a new antibody (light blue) that neutralizes the COVID-19 virus, by binding to the virus’s spike protein (grey) an

Updated on: April 08,2024

How B cells fight the COVID-19 virus

by Sarah C.p. Williams,Broad Institute of MIT and HarvardResearchers discovered a new antibody (light blue) that neutralizes the COVID-19 virus, by binding to the virus’s spike protein (grey) an

Updated on:April 08,2024

Omega-3 fatty acid stops lupus trigger, but how?

by James Pestka , Sarina Gleason,Michigan State UniversityCredit: Michigan State UniversityMichigan State University scientists have received a $2.3 million, five-year National Institutes of Hea

Updated on: April 20,2024

Omega-3 fatty acid stops lupus trigger, but how?

by James Pestka , Sarina Gleason,Michigan State UniversityCredit: Michigan State UniversityMichigan State University scientists have received a $2.3 million, five-year National Institutes of Hea

Updated on:April 20,2024

Lymph node-like biomaterial scaffold for augmenting CAR-T cell therapy

byScience China PressOn the top, the schematic illustration shows the structure of scaffold, the seeding and proliferation of CAR-T cells within the scaffold after intratumor injection. On the b

Updated on: March 27,2024

Lymph node-like biomaterial scaffold for augmenting CAR-T cell therapy

byScience China PressOn the top, the schematic illustration shows the structure of scaffold, the seeding and proliferation of CAR-T cells within the scaffold after intratumor injection. On the b

Updated on:March 27,2024

How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on: March 27,2024

How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on:March 27,2024

Nasopharyngeal carcinoma treatment using exosomes derived from γδ-T cells synergized with radiotherapy

by The University of Hong KongExos induce apoptosis of NPC tumor cells through death receptor ligation. NPC43 or C666-1 cells were treated with PBS, ultracentrifuged pellets isolated from FBS–exo

Updated on: May 07,2024

Nasopharyngeal carcinoma treatment using exosomes derived from γδ-T cells synergized with radiotherapy

by The University of Hong KongExos induce apoptosis of NPC tumor cells through death receptor ligation. NPC43 or C666-1 cells were treated with PBS, ultracentrifuged pellets isolated from FBS–exo

Updated on:May 07,2024

Fecal microbiota transplantation for active peripheral psoriatic arthritis shows no advantage

by European Alliance of Associations for RheumatologyCredit: CC0 Public DomainIn this proof-of-concept study, Maja Skov Kragsnaes and colleagues evaluated efficacy and safety of FMT in people with pso

Updated on: June 17,2024

Fecal microbiota transplantation for active peripheral psoriatic arthritis shows no advantage

by European Alliance of Associations for RheumatologyCredit: CC0 Public DomainIn this proof-of-concept study, Maja Skov Kragsnaes and colleagues evaluated efficacy and safety of FMT in people with pso

Updated on:June 17,2024

Monash researchers bringing hope to lupus patients

by Monash UniversityResearchers at Monash University are leading the world's largest study to describe lupus patients and disease characteristics, bringing treat-to-target options for lupus a

Updated on: March 24,2024

Monash researchers bringing hope to lupus patients

by Monash UniversityResearchers at Monash University are leading the world's largest study to describe lupus patients and disease characteristics, bringing treat-to-target options for lupus a

Updated on:March 24,2024

Researchers discover immune system changes that support peanut allergy remission in children

by Murdoch Children's Research InstituteResearchers have discovered the key immunological changes that support the remission of peanut allergy in children, paving the way for new, more target

Updated on: May 05,2024

Researchers discover immune system changes that support peanut allergy remission in children

by Murdoch Children's Research InstituteResearchers have discovered the key immunological changes that support the remission of peanut allergy in children, paving the way for new, more target

Updated on:May 05,2024

PFAS can suppress white blood cell's ability to destroy invaders

by Tracey Peake,North Carolina State UniversityPFASs used in this study. Names and structures of the PFASs used in this study. Vendors and CAS-RN numbers are provided in Table 1. Chemical struct

Updated on: April 20,2024

PFAS can suppress white blood cell's ability to destroy invaders

by Tracey Peake,North Carolina State UniversityPFASs used in this study. Names and structures of the PFASs used in this study. Vendors and CAS-RN numbers are provided in Table 1. Chemical struct

Updated on:April 20,2024

Nrf2: The custodian regulating oxidative stress and immunity against acrylamide toxicity

by Tokyo University of ScienceGenetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice. Credit: Tokyo University of ScienceAcrylamide is a toxic chemical compound that affect

Updated on: April 20,2024

Nrf2: The custodian regulating oxidative stress and immunity against acrylamide toxicity

by Tokyo University of ScienceGenetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice. Credit: Tokyo University of ScienceAcrylamide is a toxic chemical compound that affect

Updated on:April 20,2024