New insights into metabolic and immune pathway interactions in obesity

byScience China PressA diagrammatic illustration represents the proposed model. The energy sensor AMPK becomes less active under energy overload conditions, which leads to hypophosphorylation of

Updated on: July 06,2024

New insights into metabolic and immune pathway interactions in obesity

byScience China PressA diagrammatic illustration represents the proposed model. The energy sensor AMPK becomes less active under energy overload conditions, which leads to hypophosphorylation of

Updated on:July 06,2024

Researchers pursuing arthritis protein

by University of CopenhagenThe healthy blood cells stem from the blood bank at Rigshospitalet in Copenhagen, and more than 50 donors have been examined with the same result. Credit: Blood cells,

Updated on: March 24,2024

Researchers pursuing arthritis protein

by University of CopenhagenThe healthy blood cells stem from the blood bank at Rigshospitalet in Copenhagen, and more than 50 donors have been examined with the same result. Credit: Blood cells,

Updated on:March 24,2024

Sublingual immunotherapy safe, effective for treating toddlers' peanut allergy

by Lori SolomonPeanut sublingual immunotherapy (SLIT) is safe and effective at inducing desensitization and remission in 1- to 4-year-old children, according to a study published online Oct. 10 in the

Updated on: June 25,2024

Sublingual immunotherapy safe, effective for treating toddlers' peanut allergy

by Lori SolomonPeanut sublingual immunotherapy (SLIT) is safe and effective at inducing desensitization and remission in 1- to 4-year-old children, according to a study published online Oct. 10 in the

Updated on:June 25,2024

Machine learning helps identify rheumatoid arthritis subtypes

byWeill Cornell Medical CollegeA machine learning model can predict lymphocyte cells with high accuracy, shown in the blue and green overlays in the middle panel, on H&E histology slides. Th

Updated on: September 02,2024

Machine learning helps identify rheumatoid arthritis subtypes

byWeill Cornell Medical CollegeA machine learning model can predict lymphocyte cells with high accuracy, shown in the blue and green overlays in the middle panel, on H&E histology slides. Th

Updated on:September 02,2024

Research unveils metabolic strategies to enhance CAR-T cell therapy

by Cactus CommunicationsChimeric antigen receptor T (CAR-T) cell therapy effectively treats hematological tumors but struggles due to metabolic challenges in the tumor microenvironment. Tumor cells di

Updated on: March 27,2024

Research unveils metabolic strategies to enhance CAR-T cell therapy

by Cactus CommunicationsChimeric antigen receptor T (CAR-T) cell therapy effectively treats hematological tumors but struggles due to metabolic challenges in the tumor microenvironment. Tumor cells di

Updated on:March 27,2024

Researchers identify genes at play in people with osteoarthritis

by Anne Sliper Midling,Norwegian University of Science and TechnologyCredit: CC0 Public DomainOsteoarthritis is the leading cause of pain and disability worldwide.There is no cure, onlypai

Updated on: April 20,2024

Researchers identify genes at play in people with osteoarthritis

by Anne Sliper Midling,Norwegian University of Science and TechnologyCredit: CC0 Public DomainOsteoarthritis is the leading cause of pain and disability worldwide.There is no cure, onlypai

Updated on:April 20,2024

How to talk to your doctor about arthritis pain

Chronic pain can be excruciating, debilitating and hard to describe.Yet the best way to get the right treatment for the exactpainyou're experiencing is to put those symptoms into words

Updated on: June 06,2024

How to talk to your doctor about arthritis pain

Chronic pain can be excruciating, debilitating and hard to describe.Yet the best way to get the right treatment for the exactpainyou're experiencing is to put those symptoms into words

Updated on:June 06,2024

Serum biomarkers can differentiate psoriatic arthritis, rheumatoid arthritis

(HealthDay)—A serum protein biomarker panel can differentiate patients with early inflammatory arthritis with psoriatic arthritis (PsA) from those with rheumatoid arthritis (RA), according to a study

Updated on: June 06,2024

Serum biomarkers can differentiate psoriatic arthritis, rheumatoid arthritis

(HealthDay)—A serum protein biomarker panel can differentiate patients with early inflammatory arthritis with psoriatic arthritis (PsA) from those with rheumatoid arthritis (RA), according to a study

Updated on:June 06,2024

Gout is primary indication in about 0.2 percent of ER visits

Gout is the primary indication in about 0.2 percent of emergency department visits annually, according to a study published online Sept. 4 inArthritis Care & Research.(HealthDay)—Gout is the

Updated on: April 08,2024

Gout is primary indication in about 0.2 percent of ER visits

Gout is the primary indication in about 0.2 percent of emergency department visits annually, according to a study published online Sept. 4 inArthritis Care & Research.(HealthDay)—Gout is the

Updated on:April 08,2024

Anaphylaxis treatment remains confusing for patients, caregivers and emergency personnel, research finds

byAmerican College of Allergy, Asthma, and ImmunologyCredit: Unsplash/CC0 Public DomainAnaphylaxis can come on suddenly and without warning, and because its symptoms can be fatal, it is scary fo

Updated on: November 01,2024

Anaphylaxis treatment remains confusing for patients, caregivers and emergency personnel, research finds

byAmerican College of Allergy, Asthma, and ImmunologyCredit: Unsplash/CC0 Public DomainAnaphylaxis can come on suddenly and without warning, and because its symptoms can be fatal, it is scary fo

Updated on:November 01,2024

How one patient's rare mutation helped solve a mycobacterial mystery

by Katherine Fenz,Rockefeller UniversityGraphical Abstract. Credit:Cell(2020). DOI: 10.1016/j.cell.2020.10.046Just because you are exposed to a pathogen does not mean you will become

Updated on: May 05,2024

How one patient's rare mutation helped solve a mycobacterial mystery

by Katherine Fenz,Rockefeller UniversityGraphical Abstract. Credit:Cell(2020). DOI: 10.1016/j.cell.2020.10.046Just because you are exposed to a pathogen does not mean you will become

Updated on:May 05,2024

ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis

by Osaka UniversityE-NTPD8 in colonic epithelial cells maintains gut homeostasis through the hydrolysis of luminal ATP produced by commensal bacteria (left). An increased level of luminal ATP cau

Updated on: April 08,2024

ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis

by Osaka UniversityE-NTPD8 in colonic epithelial cells maintains gut homeostasis through the hydrolysis of luminal ATP produced by commensal bacteria (left). An increased level of luminal ATP cau

Updated on:April 08,2024