Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on: January 11,2025

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on:January 11,2025

Evolutionary origin of mysterious immune system molecule in humans revealed

by Ashley WennersHerron,Pennsylvania State UniversityThe Joining chain shares three characteristics with the CXCL chemokine genes, including the same number of exons, which encode the protein, a

Updated on: April 22,2024

Evolutionary origin of mysterious immune system molecule in humans revealed

by Ashley WennersHerron,Pennsylvania State UniversityThe Joining chain shares three characteristics with the CXCL chemokine genes, including the same number of exons, which encode the protein, a

Updated on:April 22,2024

Clinical trial denounces use of platelet-rich plasma injections for knee joint osteoarthritis

by University of MelbournePlatelet-rich plasma injections have become a popular form of treatment for painful joints in recent years but researchers have established they are no better than place

Updated on: April 20,2024

Clinical trial denounces use of platelet-rich plasma injections for knee joint osteoarthritis

by University of MelbournePlatelet-rich plasma injections have become a popular form of treatment for painful joints in recent years but researchers have established they are no better than place

Updated on:April 20,2024

Oral deucravacitinib benefits patients with lupus

by WileyCredit: CC0 Public DomainTyrosine kinases are enzymes that play central roles in signaling by cytokines involved in the pathogenesis of autoimmune diseases, including lupus. A recent phas

Updated on: June 06,2024

Oral deucravacitinib benefits patients with lupus

by WileyCredit: CC0 Public DomainTyrosine kinases are enzymes that play central roles in signaling by cytokines involved in the pathogenesis of autoimmune diseases, including lupus. A recent phas

Updated on:June 06,2024

The secret lives of T cell receptors and their role in the immune response

by Delthia Ricks , Medical XpressCredit: CC0 Public DomainCanadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components inte

Updated on: May 05,2024

The secret lives of T cell receptors and their role in the immune response

by Delthia Ricks , Medical XpressCredit: CC0 Public DomainCanadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components inte

Updated on:May 05,2024

Knee sound based detector for osteoarthritis prediction

by University of MalayaMicrophone attached to subject’s kneeUniversity Malaya researchers have developed a non-invasive, radiation-free, early stage detection system called the Knee Sound Detector to

Updated on: May 29,2024

Knee sound based detector for osteoarthritis prediction

by University of MalayaMicrophone attached to subject’s kneeUniversity Malaya researchers have developed a non-invasive, radiation-free, early stage detection system called the Knee Sound Detector to

Updated on:May 29,2024

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

Updated on: April 20,2024

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

Updated on:April 20,2024

Polycyclic aromatic hydrocarbons strongly linked to raised rheumatoid arthritis risk

by British Medical JournalCredit: Unsplash/CC0 Public DomainThe amount of environmental exposure to polycyclic aromatic hydrocarbons, or PAH for short, is strongly linked to a person's risk o

Updated on: July 03,2024

Polycyclic aromatic hydrocarbons strongly linked to raised rheumatoid arthritis risk

by British Medical JournalCredit: Unsplash/CC0 Public DomainThe amount of environmental exposure to polycyclic aromatic hydrocarbons, or PAH for short, is strongly linked to a person's risk o

Updated on:July 03,2024

COVID-19 causes some patients' immune systems to attack their own bodies, which may contribute to severe illness

by Matthew Woodruff,The ConversationCredit: Pixabay/CC0 Public DomainAround the world, immunologists who retooled their labs to join the fight against SARS-CoV-2 are furiously trying to explain

Updated on: April 10,2024

COVID-19 causes some patients' immune systems to attack their own bodies, which may contribute to severe illness

by Matthew Woodruff,The ConversationCredit: Pixabay/CC0 Public DomainAround the world, immunologists who retooled their labs to join the fight against SARS-CoV-2 are furiously trying to explain

Updated on:April 10,2024

COVID-19 virus helps block host immunity

by Mary Ann Liebert, IncSARS-CoV-2 (shown here in an electron microscopy image). Credit: National Institute of Allergy and Infectious Diseases, NIHSARS-CoV-2, the virus that causes COVID-19, bloc

Updated on: April 10,2024

COVID-19 virus helps block host immunity

by Mary Ann Liebert, IncSARS-CoV-2 (shown here in an electron microscopy image). Credit: National Institute of Allergy and Infectious Diseases, NIHSARS-CoV-2, the virus that causes COVID-19, bloc

Updated on:April 10,2024

Impact of dietary interventions inconsistent in rheumatoid arthritis

(HealthDay)—For patients with rheumatoid arthritis (RA), the impact of dietary interventions is inconsistent, although some research indicates benefit for omega-3 supplementation, according to a revie

Updated on: April 07,2024

Impact of dietary interventions inconsistent in rheumatoid arthritis

(HealthDay)—For patients with rheumatoid arthritis (RA), the impact of dietary interventions is inconsistent, although some research indicates benefit for omega-3 supplementation, according to a revie

Updated on:April 07,2024

Initial SARS-CoV-2 vaccinations prime immune cells to respond to subsequent variants, study finds

by Perelman School of Medicine at the University of PennsylvaniaGraphical abstract. Credit:Immunity(2024). DOI: 10.1016/j.immuni.2024.02.017A new study from the Perelman School of Med

Updated on: March 19,2024

Initial SARS-CoV-2 vaccinations prime immune cells to respond to subsequent variants, study finds

by Perelman School of Medicine at the University of PennsylvaniaGraphical abstract. Credit:Immunity(2024). DOI: 10.1016/j.immuni.2024.02.017A new study from the Perelman School of Med

Updated on:March 19,2024