Using molecular scissors to improve CAR-T cell therapy

by Susan Buckles,Mayo ClinicAn in vitro model for chronic stimulation induces phenotypic and functional signs of exhaustion in CART19-28ζ cells. Credit:Nature Communications(2024). D

Updated on: September 18,2024

Using molecular scissors to improve CAR-T cell therapy

by Susan Buckles,Mayo ClinicAn in vitro model for chronic stimulation induces phenotypic and functional signs of exhaustion in CART19-28ζ cells. Credit:Nature Communications(2024). D

Updated on:September 18,2024

Study sheds light on pregnancy complications and overturns common belief

by Hospital for Special Surgery"Many doctors may be unnecessarily treating some pregnant women who have antiphospholipid antibodies (aPLs) with anticoagulants, such as expensive heparin inje

Updated on: April 17,2024

Study sheds light on pregnancy complications and overturns common belief

by Hospital for Special Surgery"Many doctors may be unnecessarily treating some pregnant women who have antiphospholipid antibodies (aPLs) with anticoagulants, such as expensive heparin inje

Updated on:April 17,2024

Language barriers may cause some children to be underdiagnosed for allergic conditions

byAmerican College of Allergy, Asthma, and ImmunologyCredit: CC0 Public DomainAbout 20% of the US population speaks a language other than English when they are at home. The abundance of language

Updated on: March 05,2024

Language barriers may cause some children to be underdiagnosed for allergic conditions

byAmerican College of Allergy, Asthma, and ImmunologyCredit: CC0 Public DomainAbout 20% of the US population speaks a language other than English when they are at home. The abundance of language

Updated on:March 05,2024

Running, even in excess, doesn't lead to more osteoarthritis and hip replacements

by Dan Krotz,Lawrence Berkeley National LaboratoryCredit: Berkeley Lab photographer Roy Kaltschmidt(Medical Xpress)—Need another reason to dust off those running shoes in the back of the closet?

Updated on: June 06,2024

Running, even in excess, doesn't lead to more osteoarthritis and hip replacements

by Dan Krotz,Lawrence Berkeley National LaboratoryCredit: Berkeley Lab photographer Roy Kaltschmidt(Medical Xpress)—Need another reason to dust off those running shoes in the back of the closet?

Updated on:June 06,2024

Researchers develop statistical method for genetic mapping of autoimmune diseases

byBrigham and Women’s HospitalSchematic overview of SCENT and SCENT enhancer–gene pairs across nine single-cell multimodal datasets.a, SCENT identifies (1) activecis-regulatory regio

Updated on: April 27,2024

Researchers develop statistical method for genetic mapping of autoimmune diseases

byBrigham and Women’s HospitalSchematic overview of SCENT and SCENT enhancer–gene pairs across nine single-cell multimodal datasets.a, SCENT identifies (1) activecis-regulatory regio

Updated on:April 27,2024

COVID-19 causes some patients' immune systems to attack their own bodies, which may contribute to severe illness

by Matthew Woodruff,The ConversationCredit: Pixabay/CC0 Public DomainAround the world, immunologists who retooled their labs to join the fight against SARS-CoV-2 are furiously trying to explain

Updated on: April 10,2024

COVID-19 causes some patients' immune systems to attack their own bodies, which may contribute to severe illness

by Matthew Woodruff,The ConversationCredit: Pixabay/CC0 Public DomainAround the world, immunologists who retooled their labs to join the fight against SARS-CoV-2 are furiously trying to explain

Updated on:April 10,2024

COVID-19 virus helps block host immunity

by Mary Ann Liebert, IncSARS-CoV-2 (shown here in an electron microscopy image). Credit: National Institute of Allergy and Infectious Diseases, NIHSARS-CoV-2, the virus that causes COVID-19, bloc

Updated on: April 10,2024

COVID-19 virus helps block host immunity

by Mary Ann Liebert, IncSARS-CoV-2 (shown here in an electron microscopy image). Credit: National Institute of Allergy and Infectious Diseases, NIHSARS-CoV-2, the virus that causes COVID-19, bloc

Updated on:April 10,2024

The anterior chamber of the eye as a servant to medical research

by Karolinska InstitutetCredit: B Henrique, PixabayTo mechanistically understand what happens in the living body under physiological and pathological conditions, requires a non-invasive high spat

Updated on: March 07,2024

The anterior chamber of the eye as a servant to medical research

by Karolinska InstitutetCredit: B Henrique, PixabayTo mechanistically understand what happens in the living body under physiological and pathological conditions, requires a non-invasive high spat

Updated on:March 07,2024

Clinical trial denounces use of platelet-rich plasma injections for knee joint osteoarthritis

by University of MelbournePlatelet-rich plasma injections have become a popular form of treatment for painful joints in recent years but researchers have established they are no better than place

Updated on: April 20,2024

Clinical trial denounces use of platelet-rich plasma injections for knee joint osteoarthritis

by University of MelbournePlatelet-rich plasma injections have become a popular form of treatment for painful joints in recent years but researchers have established they are no better than place

Updated on:April 20,2024

The secret lives of T cell receptors and their role in the immune response

by Delthia Ricks , Medical XpressCredit: CC0 Public DomainCanadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components inte

Updated on: May 05,2024

The secret lives of T cell receptors and their role in the immune response

by Delthia Ricks , Medical XpressCredit: CC0 Public DomainCanadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components inte

Updated on:May 05,2024

Evolutionary origin of mysterious immune system molecule in humans revealed

by Ashley WennersHerron,Pennsylvania State UniversityThe Joining chain shares three characteristics with the CXCL chemokine genes, including the same number of exons, which encode the protein, a

Updated on: April 22,2024

Evolutionary origin of mysterious immune system molecule in humans revealed

by Ashley WennersHerron,Pennsylvania State UniversityThe Joining chain shares three characteristics with the CXCL chemokine genes, including the same number of exons, which encode the protein, a

Updated on:April 22,2024

CAR T cell therapy effective as first-line treatment for high-risk large B-cell lymphoma

by University of Texas M. D. Anderson Cancer CenterCredit: CC0 Public DomainA study led by researchers at The University of Texas MD Anderson Cancer Center found that axi-cel, an autologous anti-

Updated on: April 09,2024

CAR T cell therapy effective as first-line treatment for high-risk large B-cell lymphoma

by University of Texas M. D. Anderson Cancer CenterCredit: CC0 Public DomainA study led by researchers at The University of Texas MD Anderson Cancer Center found that axi-cel, an autologous anti-

Updated on:April 09,2024