Immune system's moonlighters point the way to a new therapeutic target

FEBRUARY 20, 2024byCold Spring Harbor LaboratoryGraphical abstract. Credit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.01.007Our immune system is remarkably powerful. It quickly

Updated on: March 25,2024

Immune system's moonlighters point the way to a new therapeutic target

FEBRUARY 20, 2024byCold Spring Harbor LaboratoryGraphical abstract. Credit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.01.007Our immune system is remarkably powerful. It quickly

Updated on:March 25,2024

Language barriers may cause some children to be underdiagnosed for allergic conditions

byAmerican College of Allergy, Asthma, and ImmunologyCredit: CC0 Public DomainAbout 20% of the US population speaks a language other than English when they are at home. The abundance of language

Updated on: March 05,2024

Language barriers may cause some children to be underdiagnosed for allergic conditions

byAmerican College of Allergy, Asthma, and ImmunologyCredit: CC0 Public DomainAbout 20% of the US population speaks a language other than English when they are at home. The abundance of language

Updated on:March 05,2024

Flu vaccine cuts mortality in rheumatoid arthritis patients

(HealthDay)—Patients with rheumatoid arthritis (RA), particularly elderly patients, who receive the influenza vaccine have significantly lower morbidity and mortality, according to a study published i

Updated on: April 17,2024

Flu vaccine cuts mortality in rheumatoid arthritis patients

(HealthDay)—Patients with rheumatoid arthritis (RA), particularly elderly patients, who receive the influenza vaccine have significantly lower morbidity and mortality, according to a study published i

Updated on:April 17,2024

Evolutionary origin of mysterious immune system molecule in humans revealed

by Ashley WennersHerron,Pennsylvania State UniversityThe Joining chain shares three characteristics with the CXCL chemokine genes, including the same number of exons, which encode the protein, a

Updated on: April 22,2024

Evolutionary origin of mysterious immune system molecule in humans revealed

by Ashley WennersHerron,Pennsylvania State UniversityThe Joining chain shares three characteristics with the CXCL chemokine genes, including the same number of exons, which encode the protein, a

Updated on:April 22,2024

TET proteins regulate factors essential for normal antibody production

by La Jolla Institute for ImmunologyMutant B cells lacking TET2 and TET3 produce an overabundance of a class of antibody called IgM, whereas normal control B cells churned out more effective antibodie

Updated on: April 24,2024

TET proteins regulate factors essential for normal antibody production

by La Jolla Institute for ImmunologyMutant B cells lacking TET2 and TET3 produce an overabundance of a class of antibody called IgM, whereas normal control B cells churned out more effective antibodie

Updated on:April 24,2024

Study uncovers novel mechanisms behind food allergies

by Melissa Rohman,Northwestern UniversityCredit:Mucosal Immunology(2023). DOI: 10.1016/j.mucimm.2023.12.001A recent Northwestern Medicine study has shed light on the mechanisms of a

Updated on: March 19,2024

Study uncovers novel mechanisms behind food allergies

by Melissa Rohman,Northwestern UniversityCredit:Mucosal Immunology(2023). DOI: 10.1016/j.mucimm.2023.12.001A recent Northwestern Medicine study has shed light on the mechanisms of a

Updated on:March 19,2024

New Anti-inflammatory Therapy Strategy: Targeted Inhibition of Inflammation by IDO and Galectin-3 Fusion

Updated on: September 21,2024

New Anti-inflammatory Therapy Strategy: Targeted Inhibition of Inflammation by IDO and Galectin-3 Fusion

Updated on:September 21,2024

Hope for patients with rare Sjögren's syndrome

by Newcastle UniversityProfessor Fai Ng. Credit: Newcastle UniversityA new study has shed light on a debilitating autoimmune condition by identifying a number of subtypes of the disease which cou

Updated on: March 24,2024

Hope for patients with rare Sjögren's syndrome

by Newcastle UniversityProfessor Fai Ng. Credit: Newcastle UniversityA new study has shed light on a debilitating autoimmune condition by identifying a number of subtypes of the disease which cou

Updated on:March 24,2024

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

Updated on: April 20,2024

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

Updated on:April 20,2024

Researchers uncover new mode of action for HUMIRA in rheumatoid arthritis patients

by Rockefeller University PressIn the presence of adalimumab, TNF on the surface of a monocyte interacts with receptor molecules on the surface of two regulatory T cells, thereby promoting their

Updated on: March 24,2024

Researchers uncover new mode of action for HUMIRA in rheumatoid arthritis patients

by Rockefeller University PressIn the presence of adalimumab, TNF on the surface of a monocyte interacts with receptor molecules on the surface of two regulatory T cells, thereby promoting their

Updated on:March 24,2024

Smokers who consume too much sodium at greater risk of developing rheumatoid arthritis

by Oxford University PressCredit: Vera Kratochvil/public domainA new study published online in the journalRheumatologytoday indicates that the interaction between high sodium intake a

Updated on: May 13,2024

Smokers who consume too much sodium at greater risk of developing rheumatoid arthritis

by Oxford University PressCredit: Vera Kratochvil/public domainA new study published online in the journalRheumatologytoday indicates that the interaction between high sodium intake a

Updated on:May 13,2024

Researchers reveal molecular mechanism of cytokine storm induced by coronavirus

by Zhang Nannan,Chinese Academy of SciencesSARS-CoV-2 stabilizes host mRNAs to induce cytokine storm. Credit: Xue Yuanchao's groupIn the past four years, the pathogen responsible for Coronav

Updated on: January 26,2024

Researchers reveal molecular mechanism of cytokine storm induced by coronavirus

by Zhang Nannan,Chinese Academy of SciencesSARS-CoV-2 stabilizes host mRNAs to induce cytokine storm. Credit: Xue Yuanchao's groupIn the past four years, the pathogen responsible for Coronav

Updated on:January 26,2024