A gene that plays a critical role in natural killer cell differentiation

by Bob Yirka , Medical XpressAn illustration of natural killer cells. Credit: Val Altounian / AAASA large team of researchers affiliated with a host of institutions in Europe and the U.S. has found a

Updated on: March 25,2024 17

A gene that plays a critical role in natural killer cell differentiation

by Bob Yirka , Medical XpressAn illustration of natural killer cells. Credit: Val Altounian / AAASA large team of researchers affiliated with a host of institutions in Europe and the U.S. has found a

Updated on:March 25,2024 17

STIM-mediated calcium influx regulates maintenance and selection of germinal center B cells: Study

by Osaka UniversityCredit:Journal of Experimental Medicine(2023). DOI: 10.1084/jem.20222178Germinal centers (GCs) are specialized microenvironments where antigen (Ag)-specific B cells

Updated on: April 22,2024 13

STIM-mediated calcium influx regulates maintenance and selection of germinal center B cells: Study

by Osaka UniversityCredit:Journal of Experimental Medicine(2023). DOI: 10.1084/jem.20222178Germinal centers (GCs) are specialized microenvironments where antigen (Ag)-specific B cells

Updated on:April 22,2024 13

What do you know about rheumatic diseases?

by Laurel Kelly, Mayo Clinic News NetworkCredit: CC0 Public DomainSeptember is Rheumatic Disease Awareness Month, which makes this a good time to learn about four common rheumatic diseases: Ankylosing

Updated on: June 26,2024 3

What do you know about rheumatic diseases?

by Laurel Kelly, Mayo Clinic News NetworkCredit: CC0 Public DomainSeptember is Rheumatic Disease Awareness Month, which makes this a good time to learn about four common rheumatic diseases: Ankylosing

Updated on:June 26,2024 3

An AI strategy for identifying new immunotherapy targets

by Cleveland ClinicSlowest relaxation timescales estimated by unsupervised AI highlight concerted MHC–peptide dynamics and multiple peptide presentation modes. Credit:Briefings in Bioinform

Updated on: March 07,2024 19

An AI strategy for identifying new immunotherapy targets

by Cleveland ClinicSlowest relaxation timescales estimated by unsupervised AI highlight concerted MHC–peptide dynamics and multiple peptide presentation modes. Credit:Briefings in Bioinform

Updated on:March 07,2024 19

Interdisciplinary guidelines to optimize the treatment of childhood arthritis

by Aarhus UniversityCredit: Unsplash/CC0 Public DomainPreviously, there were no uniform guidelines for the treatment of arthritis of the jaw, a potentially debilitating consequence of juvenile ar

Updated on: April 07,2024 19

Interdisciplinary guidelines to optimize the treatment of childhood arthritis

by Aarhus UniversityCredit: Unsplash/CC0 Public DomainPreviously, there were no uniform guidelines for the treatment of arthritis of the jaw, a potentially debilitating consequence of juvenile ar

Updated on:April 07,2024 19

Gender, high DAS28-P index predictive of pain in early RA

(HealthDay) -- For patients with rheumatoid arthritis (RA), female gender and having a high proportion of disease activity score (DAS28) attributable to patient-reported components (joint tenderness a

Updated on: April 08,2024 17

Gender, high DAS28-P index predictive of pain in early RA

(HealthDay) -- For patients with rheumatoid arthritis (RA), female gender and having a high proportion of disease activity score (DAS28) attributable to patient-reported components (joint tenderness a

Updated on:April 08,2024 17

CARv3-TEAM-E T-cell treatment beneficial for recurrent glioblastoma

by Elana GotkineFor patients with recurrent glioblastoma, treatment with chimeric antigen receptor (CAR) T-cells engineered to target the epidermal growth factor receptor (EGFR) variant III tumor-spec

Updated on: March 27,2024 0

CARv3-TEAM-E T-cell treatment beneficial for recurrent glioblastoma

by Elana GotkineFor patients with recurrent glioblastoma, treatment with chimeric antigen receptor (CAR) T-cells engineered to target the epidermal growth factor receptor (EGFR) variant III tumor-spec

Updated on:March 27,2024 0

Immune system's moonlighters point the way to a new therapeutic target

FEBRUARY 20, 2024byCold Spring Harbor LaboratoryGraphical abstract. Credit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.01.007Our immune system is remarkably powerful. It quickly

Updated on: March 25,2024 5

Immune system's moonlighters point the way to a new therapeutic target

FEBRUARY 20, 2024byCold Spring Harbor LaboratoryGraphical abstract. Credit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.01.007Our immune system is remarkably powerful. It quickly

Updated on:March 25,2024 5

Allergy diary' phone app classifies phenotypes in rhinitis

(HealthDay)—TheAllergy Diaryphone app can identify phenotypic differences between rhinitis groups, according to a study published online Jan. 10 inAllergy.Jean Bousquet, M.D., from t

Updated on: March 13,2024 12

Allergy diary' phone app classifies phenotypes in rhinitis

(HealthDay)—TheAllergy Diaryphone app can identify phenotypic differences between rhinitis groups, according to a study published online Jan. 10 inAllergy.Jean Bousquet, M.D., from t

Updated on:March 13,2024 12

COVID-19 increases the chance of getting an autoimmune condition

by Magdalena Plebanski, Rhiane Moody,The ConversationCredit: Unsplash/CC0 Public DomainSARS-CoV-2, the virus that causes COVID-19, can sometimes cause the immune system to mistakenly attack the

Updated on: April 13,2024 11

COVID-19 increases the chance of getting an autoimmune condition

by Magdalena Plebanski, Rhiane Moody,The ConversationCredit: Unsplash/CC0 Public DomainSARS-CoV-2, the virus that causes COVID-19, can sometimes cause the immune system to mistakenly attack the

Updated on:April 13,2024 11

Women with lupus seem at higher risk for hip fractures

by Kathleen Doheny, Healthday ReporterStudy followed nearly 15,000 patients for 6 years.(HealthDay)—Women with lupus—the autoimmune disease that can damage skin, joints and organs—also are at higher r

Updated on: April 08,2024 16

Women with lupus seem at higher risk for hip fractures

by Kathleen Doheny, Healthday ReporterStudy followed nearly 15,000 patients for 6 years.(HealthDay)—Women with lupus—the autoimmune disease that can damage skin, joints and organs—also are at higher r

Updated on:April 08,2024 16

An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on: March 30,2024 8

An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on:March 30,2024 8