Immune system's moonlighters point the way to a new therapeutic target

FEBRUARY 20, 2024byCold Spring Harbor LaboratoryGraphical abstract. Credit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.01.007Our immune system is remarkably powerful. It quickly

Updated on: March 25,2024

Immune system's moonlighters point the way to a new therapeutic target

FEBRUARY 20, 2024byCold Spring Harbor LaboratoryGraphical abstract. Credit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.01.007Our immune system is remarkably powerful. It quickly

Updated on:March 25,2024

Language barriers may cause some children to be underdiagnosed for allergic conditions

byAmerican College of Allergy, Asthma, and ImmunologyCredit: CC0 Public DomainAbout 20% of the US population speaks a language other than English when they are at home. The abundance of language

Updated on: March 05,2024

Language barriers may cause some children to be underdiagnosed for allergic conditions

byAmerican College of Allergy, Asthma, and ImmunologyCredit: CC0 Public DomainAbout 20% of the US population speaks a language other than English when they are at home. The abundance of language

Updated on:March 05,2024

Immune cells monitor blood platelet maturation in bone marrow, researchers discover

byLudwig Maximilian University of MunichTissue homeostasis: plasmacytoid dendritic cells monitor bone marrow, initiating on-demand megakaryocyte formation. Uniform distribution of megakaryocytes

Updated on: July 30,2024

Immune cells monitor blood platelet maturation in bone marrow, researchers discover

byLudwig Maximilian University of MunichTissue homeostasis: plasmacytoid dendritic cells monitor bone marrow, initiating on-demand megakaryocyte formation. Uniform distribution of megakaryocytes

Updated on:July 30,2024

Flu vaccine cuts mortality in rheumatoid arthritis patients

(HealthDay)—Patients with rheumatoid arthritis (RA), particularly elderly patients, who receive the influenza vaccine have significantly lower morbidity and mortality, according to a study published i

Updated on: April 17,2024

Flu vaccine cuts mortality in rheumatoid arthritis patients

(HealthDay)—Patients with rheumatoid arthritis (RA), particularly elderly patients, who receive the influenza vaccine have significantly lower morbidity and mortality, according to a study published i

Updated on:April 17,2024

TET proteins regulate factors essential for normal antibody production

by La Jolla Institute for ImmunologyMutant B cells lacking TET2 and TET3 produce an overabundance of a class of antibody called IgM, whereas normal control B cells churned out more effective antibodie

Updated on: April 24,2024

TET proteins regulate factors essential for normal antibody production

by La Jolla Institute for ImmunologyMutant B cells lacking TET2 and TET3 produce an overabundance of a class of antibody called IgM, whereas normal control B cells churned out more effective antibodie

Updated on:April 24,2024

SARS-CoV-2 antibodies detectable up to seven months post COVID-19 onset

by Instituto de Medicina MolecularColorized scanning electron micrograph of a dying cell (blue) heavily infected with SARS-CoV-2 (yellow), the virus that causes COVID-19. Credit: NIAID Integrated Rese

Updated on: April 10,2024

SARS-CoV-2 antibodies detectable up to seven months post COVID-19 onset

by Instituto de Medicina MolecularColorized scanning electron micrograph of a dying cell (blue) heavily infected with SARS-CoV-2 (yellow), the virus that causes COVID-19. Credit: NIAID Integrated Rese

Updated on:April 10,2024

Risk of severe breakthrough COVID-19 infection is higher for people with HIV with moderately low CD4 cell counts

by Johns Hopkins University Bloomberg School of Public HealthGraphs show incidence of severe COVID-19 breakthrough illness by HIV status (A) (log-rank test P = .40), by CD4 cell count and HIV sta

Updated on: April 09,2024

Risk of severe breakthrough COVID-19 infection is higher for people with HIV with moderately low CD4 cell counts

by Johns Hopkins University Bloomberg School of Public HealthGraphs show incidence of severe COVID-19 breakthrough illness by HIV status (A) (log-rank test P = .40), by CD4 cell count and HIV sta

Updated on:April 09,2024

The secret lives of T cell receptors and their role in the immune response

by Delthia Ricks , Medical XpressCredit: CC0 Public DomainCanadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components inte

Updated on: May 05,2024

The secret lives of T cell receptors and their role in the immune response

by Delthia Ricks , Medical XpressCredit: CC0 Public DomainCanadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components inte

Updated on:May 05,2024

Higher-dose pneumococcal vaccines improve immune response in ANCA-associated vasculitis patients receiving rituximab

by American College of RheumatologyCredit: Pixabay/CC0 Public DomainNew research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual meeting, showed tha

Updated on: May 13,2024

Higher-dose pneumococcal vaccines improve immune response in ANCA-associated vasculitis patients receiving rituximab

by American College of RheumatologyCredit: Pixabay/CC0 Public DomainNew research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual meeting, showed tha

Updated on:May 13,2024

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

Updated on: April 20,2024

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

Updated on:April 20,2024

New Anti-inflammatory Therapy Strategy: Targeted Inhibition of Inflammation by IDO and Galectin-3 Fusion

Updated on: September 21,2024

New Anti-inflammatory Therapy Strategy: Targeted Inhibition of Inflammation by IDO and Galectin-3 Fusion

Updated on:September 21,2024

Running, even in excess, doesn't lead to more osteoarthritis and hip replacements

by Dan Krotz,Lawrence Berkeley National LaboratoryCredit: Berkeley Lab photographer Roy Kaltschmidt(Medical Xpress)—Need another reason to dust off those running shoes in the back of the closet?

Updated on: June 06,2024

Running, even in excess, doesn't lead to more osteoarthritis and hip replacements

by Dan Krotz,Lawrence Berkeley National LaboratoryCredit: Berkeley Lab photographer Roy Kaltschmidt(Medical Xpress)—Need another reason to dust off those running shoes in the back of the closet?

Updated on:June 06,2024