An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on: March 30,2024

An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on:March 30,2024

Omega-3 fatty acids linked with slower progression of ALS

by Harvard T.H. Chan School of Public HealthCredit: Lawrencekhoo / Wikipedia.Consuming omega-3 fatty acids—particularly alpha-linolenic acid (ALA), a nutrient found in foods including flaxseeds,

Updated on: June 26,2024

Omega-3 fatty acids linked with slower progression of ALS

by Harvard T.H. Chan School of Public HealthCredit: Lawrencekhoo / Wikipedia.Consuming omega-3 fatty acids—particularly alpha-linolenic acid (ALA), a nutrient found in foods including flaxseeds,

Updated on:June 26,2024

Sleep deprivation may increase risk for systemic lupus in women

Lack of sleep is associated with an increased risk for systemic lupus erythematosus (SLE), particularly among women with concomitant depression or bodily pain, according to a study published online Se

Updated on: May 26,2024

Sleep deprivation may increase risk for systemic lupus in women

Lack of sleep is associated with an increased risk for systemic lupus erythematosus (SLE), particularly among women with concomitant depression or bodily pain, according to a study published online Se

Updated on:May 26,2024

A turncoat protein allows viruses to ride roughshod in the liver, paving the way to cancer

by Delthia Ricks , Medical XpressImages showing the distribution of tagged STING and HA-HPN proteins in liver cells. Credit: F. Hsin et al.,Science Signaling(2021)Chronic viral infections

Updated on: April 24,2024

A turncoat protein allows viruses to ride roughshod in the liver, paving the way to cancer

by Delthia Ricks , Medical XpressImages showing the distribution of tagged STING and HA-HPN proteins in liver cells. Credit: F. Hsin et al.,Science Signaling(2021)Chronic viral infections

Updated on:April 24,2024

Early RA treatment important for long-term outcomes

(HealthDay)—Early treatment of rheumatoid arthritis (RA) is important for long-term outcomes, and there has been a decrease in mortality rates attributable to RA, according to two studies published on

Updated on: March 28,2024

Early RA treatment important for long-term outcomes

(HealthDay)—Early treatment of rheumatoid arthritis (RA) is important for long-term outcomes, and there has been a decrease in mortality rates attributable to RA, according to two studies published on

Updated on:March 28,2024

Oral deucravacitinib benefits patients with lupus

by WileyCredit: CC0 Public DomainTyrosine kinases are enzymes that play central roles in signaling by cytokines involved in the pathogenesis of autoimmune diseases, including lupus. A recent phas

Updated on: June 06,2024

Oral deucravacitinib benefits patients with lupus

by WileyCredit: CC0 Public DomainTyrosine kinases are enzymes that play central roles in signaling by cytokines involved in the pathogenesis of autoimmune diseases, including lupus. A recent phas

Updated on:June 06,2024

Interdisciplinary guidelines to optimize the treatment of childhood arthritis

by Aarhus UniversityCredit: Unsplash/CC0 Public DomainPreviously, there were no uniform guidelines for the treatment of arthritis of the jaw, a potentially debilitating consequence of juvenile ar

Updated on: April 07,2024

Interdisciplinary guidelines to optimize the treatment of childhood arthritis

by Aarhus UniversityCredit: Unsplash/CC0 Public DomainPreviously, there were no uniform guidelines for the treatment of arthritis of the jaw, a potentially debilitating consequence of juvenile ar

Updated on:April 07,2024

COVID-19 increases the chance of getting an autoimmune condition

by Magdalena Plebanski, Rhiane Moody,The ConversationCredit: Unsplash/CC0 Public DomainSARS-CoV-2, the virus that causes COVID-19, can sometimes cause the immune system to mistakenly attack the

Updated on: April 13,2024

COVID-19 increases the chance of getting an autoimmune condition

by Magdalena Plebanski, Rhiane Moody,The ConversationCredit: Unsplash/CC0 Public DomainSARS-CoV-2, the virus that causes COVID-19, can sometimes cause the immune system to mistakenly attack the

Updated on:April 13,2024

How one inflammatory disorder exacerbates another

by Katherine Unger Baillie,University of PennsylvaniaInflammation in the gums can increase susceptibility to other forms of inflammation, such as arthritis, through changes to immune cell precur

Updated on: March 25,2024

How one inflammatory disorder exacerbates another

by Katherine Unger Baillie,University of PennsylvaniaInflammation in the gums can increase susceptibility to other forms of inflammation, such as arthritis, through changes to immune cell precur

Updated on:March 25,2024

Immune cells monitor blood platelet maturation in bone marrow, researchers discover

byLudwig Maximilian University of MunichTissue homeostasis: plasmacytoid dendritic cells monitor bone marrow, initiating on-demand megakaryocyte formation. Uniform distribution of megakaryocytes

Updated on: July 30,2024

Immune cells monitor blood platelet maturation in bone marrow, researchers discover

byLudwig Maximilian University of MunichTissue homeostasis: plasmacytoid dendritic cells monitor bone marrow, initiating on-demand megakaryocyte formation. Uniform distribution of megakaryocytes

Updated on:July 30,2024

Study sheds light on pregnancy complications and overturns common belief

by Hospital for Special Surgery"Many doctors may be unnecessarily treating some pregnant women who have antiphospholipid antibodies (aPLs) with anticoagulants, such as expensive heparin inje

Updated on: April 17,2024

Study sheds light on pregnancy complications and overturns common belief

by Hospital for Special Surgery"Many doctors may be unnecessarily treating some pregnant women who have antiphospholipid antibodies (aPLs) with anticoagulants, such as expensive heparin inje

Updated on:April 17,2024

A mathematical model that predicts how severe hay fever season will be

by Bob Yirka , Medical XpressCredit: Pixabay/CC0 Public DomainAn international team of researchers has developed a mathematical model for predicting how bad an upcoming hay fever season will be. In th

Updated on: May 07,2024

A mathematical model that predicts how severe hay fever season will be

by Bob Yirka , Medical XpressCredit: Pixabay/CC0 Public DomainAn international team of researchers has developed a mathematical model for predicting how bad an upcoming hay fever season will be. In th

Updated on:May 07,2024