Researchers develop statistical method for genetic mapping of autoimmune diseases

byBrigham and Women’s HospitalSchematic overview of SCENT and SCENT enhancer–gene pairs across nine single-cell multimodal datasets.a, SCENT identifies (1) activecis-regulatory regio

Updated on: April 27,2024

Researchers develop statistical method for genetic mapping of autoimmune diseases

byBrigham and Women’s HospitalSchematic overview of SCENT and SCENT enhancer–gene pairs across nine single-cell multimodal datasets.a, SCENT identifies (1) activecis-regulatory regio

Updated on:April 27,2024

Using molecular scissors to improve CAR-T cell therapy

by Susan Buckles,Mayo ClinicAn in vitro model for chronic stimulation induces phenotypic and functional signs of exhaustion in CART19-28ζ cells. Credit:Nature Communications(2024). D

Updated on: September 18,2024

Using molecular scissors to improve CAR-T cell therapy

by Susan Buckles,Mayo ClinicAn in vitro model for chronic stimulation induces phenotypic and functional signs of exhaustion in CART19-28ζ cells. Credit:Nature Communications(2024). D

Updated on:September 18,2024

Researchers correlate rheumatoid arthritis and giant cell arteritis with solar cycles

by John Greenwald,Princeton Plasma Physics LaboratoryAcoronal mass ejection is hurled from the sun. Credit: NASAWhat began as a chat between husband and wife has evolved into an intriguing

Updated on: June 26,2024

Researchers correlate rheumatoid arthritis and giant cell arteritis with solar cycles

by John Greenwald,Princeton Plasma Physics LaboratoryAcoronal mass ejection is hurled from the sun. Credit: NASAWhat began as a chat between husband and wife has evolved into an intriguing

Updated on:June 26,2024

Myogenes identified for spondyloarthritis synovitis

There are disease-specific and inflammation-independent stromal alterations in spondyloarthritis synovitis, according to a study published online Sept. 12 inArthritis & Rheumatism.(HealthDay

Updated on: April 08,2024

Myogenes identified for spondyloarthritis synovitis

There are disease-specific and inflammation-independent stromal alterations in spondyloarthritis synovitis, according to a study published online Sept. 12 inArthritis & Rheumatism.(HealthDay

Updated on:April 08,2024

Team explores role of 'stimulator of interferon genes' in body's innate immune system

by Tokai National Higher Education and Research SystemA graphical illustration of cholesterol- and palmitoylation-dependent STING clustering at the TGN. Credit: Institute for Glyco-core ResearchWhen p

Updated on: June 18,2024

Team explores role of 'stimulator of interferon genes' in body's innate immune system

by Tokai National Higher Education and Research SystemA graphical illustration of cholesterol- and palmitoylation-dependent STING clustering at the TGN. Credit: Institute for Glyco-core ResearchWhen p

Updated on:June 18,2024

Sex-specific immune response in COVID-19 linked to cellular metabolism

by Rick Harrison,Yale UniversityImage of the ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV). Credit: CDCResearchers studying COVID-19 patients have found a metabo

Updated on: April 13,2024

Sex-specific immune response in COVID-19 linked to cellular metabolism

by Rick Harrison,Yale UniversityImage of the ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV). Credit: CDCResearchers studying COVID-19 patients have found a metabo

Updated on:April 13,2024

How do MAIT cells identify and attack foreign invaders?

byUniversity of MelbourneCredit: CC0 Public DomainMelbourne researchers have identified what makes a specialised immune cell, known as mucosal-associated invariant T (MAIT), cells boost their nu

Updated on: April 20,2024

How do MAIT cells identify and attack foreign invaders?

byUniversity of MelbourneCredit: CC0 Public DomainMelbourne researchers have identified what makes a specialised immune cell, known as mucosal-associated invariant T (MAIT), cells boost their nu

Updated on:April 20,2024

Researchers reveal molecular mechanism of cytokine storm induced by coronavirus

by Zhang Nannan,Chinese Academy of SciencesSARS-CoV-2 stabilizes host mRNAs to induce cytokine storm. Credit: Xue Yuanchao's groupIn the past four years, the pathogen responsible for Coronav

Updated on: January 26,2024

Researchers reveal molecular mechanism of cytokine storm induced by coronavirus

by Zhang Nannan,Chinese Academy of SciencesSARS-CoV-2 stabilizes host mRNAs to induce cytokine storm. Credit: Xue Yuanchao's groupIn the past four years, the pathogen responsible for Coronav

Updated on:January 26,2024

Clinical trial denounces use of platelet-rich plasma injections for knee joint osteoarthritis

by University of MelbournePlatelet-rich plasma injections have become a popular form of treatment for painful joints in recent years but researchers have established they are no better than place

Updated on: April 20,2024

Clinical trial denounces use of platelet-rich plasma injections for knee joint osteoarthritis

by University of MelbournePlatelet-rich plasma injections have become a popular form of treatment for painful joints in recent years but researchers have established they are no better than place

Updated on:April 20,2024

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

Updated on: April 20,2024

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

Updated on:April 20,2024

A novel animal model for analysing human natural killer cell functions in vivo

by Kawasaki CityFigure 1: Humanized mice were generated by transplanting 2.5 x 104 human cord blood-derived CD34+ HSC cells into irradiated NOG-IL-2 mice. After human CD34+ cell transplantation, human

Updated on: March 25,2024

A novel animal model for analysing human natural killer cell functions in vivo

by Kawasaki CityFigure 1: Humanized mice were generated by transplanting 2.5 x 104 human cord blood-derived CD34+ HSC cells into irradiated NOG-IL-2 mice. After human CD34+ cell transplantation, human

Updated on:March 25,2024

Scientists create device to deliver immunotherapy without side effects

by Houston MethodistSmaller than a grain of rice, this tiny nanodevice, invented by a Houston Methodist scientist, delivers immunotherapy straight into a tumor, eliminating both side effects and

Updated on: April 22,2024

Scientists create device to deliver immunotherapy without side effects

by Houston MethodistSmaller than a grain of rice, this tiny nanodevice, invented by a Houston Methodist scientist, delivers immunotherapy straight into a tumor, eliminating both side effects and

Updated on:April 22,2024