A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on: May 07,2024

A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on:May 07,2024

Chromosomal loop signatures could identify poor drug response in arthritis

by University of GlasgowCredit: University of GlasgowChromosomal loop signatures found in blood samples obtained in early rheumatoid arthritis could identify patients that will not respond adequa

Updated on: April 17,2024

Chromosomal loop signatures could identify poor drug response in arthritis

by University of GlasgowCredit: University of GlasgowChromosomal loop signatures found in blood samples obtained in early rheumatoid arthritis could identify patients that will not respond adequa

Updated on:April 17,2024

A stealthy way to combat tumors

by Anne Trafton,Massachusetts Institute of TechnologyMIT researchers have identified a specialized subset of dendritic cells that help stimulate T cells to attack tumors. In this image, the blue

Updated on: May 07,2024

A stealthy way to combat tumors

by Anne Trafton,Massachusetts Institute of TechnologyMIT researchers have identified a specialized subset of dendritic cells that help stimulate T cells to attack tumors. In this image, the blue

Updated on:May 07,2024

Abatacept therapy offers promising results for treating juvenile dermatomyositis

by George Washington UniversityScreening, Trial Entry and Outcome. Credit:Arthritis & Rheumatology(2023). DOI: 10.1002/art.42450Juvenile dermatomyositis, a rare but often severe a

Updated on: May 29,2024

Abatacept therapy offers promising results for treating juvenile dermatomyositis

by George Washington UniversityScreening, Trial Entry and Outcome. Credit:Arthritis & Rheumatology(2023). DOI: 10.1002/art.42450Juvenile dermatomyositis, a rare but often severe a

Updated on:May 29,2024

CRISPR screen reveals loss of genes in interferon gamma receptor signaling pathway

by Massachusetts General HospitalGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0Researchers at Massachusetts General Hospital (MGH) have discovered that the interferon gamma recept

Updated on: April 13,2024

CRISPR screen reveals loss of genes in interferon gamma receptor signaling pathway

by Massachusetts General HospitalGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0Researchers at Massachusetts General Hospital (MGH) have discovered that the interferon gamma recept

Updated on:April 13,2024

Risk score predicts disease progression in patients with rheumatoid arthritis

by WileyCredit: Unsplash/CC0 Public DomainScientists have created a risk score based on thousands of genetic variants to determine the prognosis of individual patients with rheumatoid arthritis.I

Updated on: June 17,2024

Risk score predicts disease progression in patients with rheumatoid arthritis

by WileyCredit: Unsplash/CC0 Public DomainScientists have created a risk score based on thousands of genetic variants to determine the prognosis of individual patients with rheumatoid arthritis.I

Updated on:June 17,2024

Study finds COVID-19 vaccine not associated with severe disease flare in patients with rheumatic diseases

by American College of RheumatologyCredit: Unsplash/CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that the

Updated on: June 17,2024

Study finds COVID-19 vaccine not associated with severe disease flare in patients with rheumatic diseases

by American College of RheumatologyCredit: Unsplash/CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that the

Updated on:June 17,2024

Redundancies in T cells

by Fabio Bergamin,ETH ZurichCredit: AI-generated imageResearchers at ETH Zurich have discovered redundancies in the biochemical signalling pathways of immune cells. This finding has important im

Updated on: May 05,2024

Redundancies in T cells

by Fabio Bergamin,ETH ZurichCredit: AI-generated imageResearchers at ETH Zurich have discovered redundancies in the biochemical signalling pathways of immune cells. This finding has important im

Updated on:May 05,2024

MRI-guided Tx strategy not superior for rheumatoid arthritis

(HealthDay)—A magnetic resonance imaging (MRI)-guided treat-to-target strategy is not associated with improved disease activity remission rates for patients with rheumatoid arthritis (RA) in clinical

Updated on: May 08,2024

MRI-guided Tx strategy not superior for rheumatoid arthritis

(HealthDay)—A magnetic resonance imaging (MRI)-guided treat-to-target strategy is not associated with improved disease activity remission rates for patients with rheumatoid arthritis (RA) in clinical

Updated on:May 08,2024

Uncovering the cause of regulatory T cell dysfunction in elderly-onset rheumatoid arthritis

byUniversity of TsukubaGraphical abstract. Credit:Clinical Immunology(2024). DOI: 10.1016/j.clim.2024.110337Researchers at Tsukuba University have discovered that the increase in reg

Updated on: September 02,2024

Uncovering the cause of regulatory T cell dysfunction in elderly-onset rheumatoid arthritis

byUniversity of TsukubaGraphical abstract. Credit:Clinical Immunology(2024). DOI: 10.1016/j.clim.2024.110337Researchers at Tsukuba University have discovered that the increase in reg

Updated on:September 02,2024

Patients with rheumatic and musculoskeletal conditions vulnerable to long term opioid use

by British Medical JournalCredit: Unsplash/CC0 Public DomainPatients with rheumatic and musculoskeletal conditions are vulnerable to long term opioid use, with up to 1 in 3 of those with rheumato

Updated on: June 15,2024

Patients with rheumatic and musculoskeletal conditions vulnerable to long term opioid use

by British Medical JournalCredit: Unsplash/CC0 Public DomainPatients with rheumatic and musculoskeletal conditions are vulnerable to long term opioid use, with up to 1 in 3 of those with rheumato

Updated on:June 15,2024

Fracture risk down with adherence to bisphosphonates

For patients with an osteoporotic fracture, adherence to bisphosphonate treatment is associated with reduced fracture risk; and for veterans with rheumatoid arthritis, non-adherence to bisphosphonate

Updated on: March 24,2024

Fracture risk down with adherence to bisphosphonates

For patients with an osteoporotic fracture, adherence to bisphosphonate treatment is associated with reduced fracture risk; and for veterans with rheumatoid arthritis, non-adherence to bisphosphonate

Updated on:March 24,2024