Inflammation can lead to circadian sleep disorders

by Northwestern UniversityCredit: CC0 Public DomainInflammation, which is the root cause of autoimmune disorders including arthritis, Type 1 diabetes, irritable bowel syndrome and Crohn's dis

Updated on: April 16,2024

Inflammation can lead to circadian sleep disorders

by Northwestern UniversityCredit: CC0 Public DomainInflammation, which is the root cause of autoimmune disorders including arthritis, Type 1 diabetes, irritable bowel syndrome and Crohn's dis

Updated on:April 16,2024

Researchers pursuing arthritis protein

by University of CopenhagenThe healthy blood cells stem from the blood bank at Rigshospitalet in Copenhagen, and more than 50 donors have been examined with the same result. Credit: Blood cells,

Updated on: March 24,2024

Researchers pursuing arthritis protein

by University of CopenhagenThe healthy blood cells stem from the blood bank at Rigshospitalet in Copenhagen, and more than 50 donors have been examined with the same result. Credit: Blood cells,

Updated on:March 24,2024

The 'greying' of T cells: Scientists pinpoint metabolic pathway behind age-related immunity loss

by Harvard Medical SchoolCredit: CC0 Public DomainThe elderly suffer more serious complications from infections and benefit less from vaccination than the general population. Scientists have long

Updated on: May 06,2024

The 'greying' of T cells: Scientists pinpoint metabolic pathway behind age-related immunity loss

by Harvard Medical SchoolCredit: CC0 Public DomainThe elderly suffer more serious complications from infections and benefit less from vaccination than the general population. Scientists have long

Updated on:May 06,2024

A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on: May 07,2024

A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on:May 07,2024

One step closer to tailored treatment of severe rheumatic diseases

by Aarhus UniversityThe study leads us to hope that the immunological cells and inflammatory signalling molecules in the joint of each individual patient will be able to predict the most effectiv

Updated on: June 17,2024

One step closer to tailored treatment of severe rheumatic diseases

by Aarhus UniversityThe study leads us to hope that the immunological cells and inflammatory signalling molecules in the joint of each individual patient will be able to predict the most effectiv

Updated on:June 17,2024

ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis

by Osaka UniversityE-NTPD8 in colonic epithelial cells maintains gut homeostasis through the hydrolysis of luminal ATP produced by commensal bacteria (left). An increased level of luminal ATP cau

Updated on: April 08,2024

ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis

by Osaka UniversityE-NTPD8 in colonic epithelial cells maintains gut homeostasis through the hydrolysis of luminal ATP produced by commensal bacteria (left). An increased level of luminal ATP cau

Updated on:April 08,2024

A protein that controls inflammation

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainA study by the research team of Prof. Geert van Loo (VIB-UGent Center for Inflammation Research) has unraveled a critical

Updated on: April 20,2024

A protein that controls inflammation

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainA study by the research team of Prof. Geert van Loo (VIB-UGent Center for Inflammation Research) has unraveled a critical

Updated on:April 20,2024

Lab-created molecule achieves positive results in the treatment of arthritis

by FAPESPArthritic mouse paw treated with TPPU (left) and untreated paw of another arthritic mouse. The substance decreased the area affected, reduced local swelling, and assuaged the pain associ

Updated on: March 24,2024

Lab-created molecule achieves positive results in the treatment of arthritis

by FAPESPArthritic mouse paw treated with TPPU (left) and untreated paw of another arthritic mouse. The substance decreased the area affected, reduced local swelling, and assuaged the pain associ

Updated on:March 24,2024

Protein eIF4A emerges as a potential Achilles' heel for triple-negative breast cancer

by Baylor College of MedicineGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI172503Improving treatments for triple-negative breast cancer (TNBC), a

Updated on: April 15,2024

Protein eIF4A emerges as a potential Achilles' heel for triple-negative breast cancer

by Baylor College of MedicineGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI172503Improving treatments for triple-negative breast cancer (TNBC), a

Updated on:April 15,2024

Uncovering the cause of regulatory T cell dysfunction in elderly-onset rheumatoid arthritis

byUniversity of TsukubaGraphical abstract. Credit:Clinical Immunology(2024). DOI: 10.1016/j.clim.2024.110337Researchers at Tsukuba University have discovered that the increase in reg

Updated on: September 02,2024

Uncovering the cause of regulatory T cell dysfunction in elderly-onset rheumatoid arthritis

byUniversity of TsukubaGraphical abstract. Credit:Clinical Immunology(2024). DOI: 10.1016/j.clim.2024.110337Researchers at Tsukuba University have discovered that the increase in reg

Updated on:September 02,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on: April 16,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on:April 16,2024

Warfarin use significantly increases risk of knee and hip replacement in people with OA

by American College of RheumatologyCredit: CC0 Public DomainNew research presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that use of warfarin, a vit

Updated on: May 23,2024

Warfarin use significantly increases risk of knee and hip replacement in people with OA

by American College of RheumatologyCredit: CC0 Public DomainNew research presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that use of warfarin, a vit

Updated on:May 23,2024