Chromosomal loop signatures could identify poor drug response in arthritis

by University of GlasgowCredit: University of GlasgowChromosomal loop signatures found in blood samples obtained in early rheumatoid arthritis could identify patients that will not respond adequa

Updated on: April 17,2024

Chromosomal loop signatures could identify poor drug response in arthritis

by University of GlasgowCredit: University of GlasgowChromosomal loop signatures found in blood samples obtained in early rheumatoid arthritis could identify patients that will not respond adequa

Updated on:April 17,2024

HSPC-derived CAR T-cells capable of lasting engraftment

(HealthDay)—Hematopoietic stem/progenitor cell (HSPC)-derived chimeric antigen receptor (CAR) T-cells are capable of long-term engraftment in a model of HIV/AIDS, according to a study published online

Updated on: April 16,2024

HSPC-derived CAR T-cells capable of lasting engraftment

(HealthDay)—Hematopoietic stem/progenitor cell (HSPC)-derived chimeric antigen receptor (CAR) T-cells are capable of long-term engraftment in a model of HIV/AIDS, according to a study published online

Updated on:April 16,2024

A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on: May 07,2024

A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on:May 07,2024

How a COVID-19 infection spurs antibodies against common colds

by The Scripps Research InstituteResearchers analyzed the structures of antibodies (colored) from healthy donors as the molecules bound to the spike protein from common coronaviruses like OC43 (s

Updated on: April 10,2024

How a COVID-19 infection spurs antibodies against common colds

by The Scripps Research InstituteResearchers analyzed the structures of antibodies (colored) from healthy donors as the molecules bound to the spike protein from common coronaviruses like OC43 (s

Updated on:April 10,2024

Study finds antibody-associated vasculitis characteristics and treatments vary across lifespan

by American College of RheumatologyMedications ever received by patients with granulomatosis with polyangiitis and microscopic polyangiitis stratified by age at diagnosis. Credit: The Association

Updated on: May 08,2024

Study finds antibody-associated vasculitis characteristics and treatments vary across lifespan

by American College of RheumatologyMedications ever received by patients with granulomatosis with polyangiitis and microscopic polyangiitis stratified by age at diagnosis. Credit: The Association

Updated on:May 08,2024

Numerous jobs linked to increased risk of knee reconstruction

by University of SydneyExercises to avoid and treat osteoarthritis. Credit: Institute of Bone and Joint Research, University of SydneyKnee replacements are a huge burden on society and individual

Updated on: June 06,2024

Numerous jobs linked to increased risk of knee reconstruction

by University of SydneyExercises to avoid and treat osteoarthritis. Credit: Institute of Bone and Joint Research, University of SydneyKnee replacements are a huge burden on society and individual

Updated on:June 06,2024

Abatacept therapy offers promising results for treating juvenile dermatomyositis

by George Washington UniversityScreening, Trial Entry and Outcome. Credit:Arthritis & Rheumatology(2023). DOI: 10.1002/art.42450Juvenile dermatomyositis, a rare but often severe a

Updated on: May 29,2024

Abatacept therapy offers promising results for treating juvenile dermatomyositis

by George Washington UniversityScreening, Trial Entry and Outcome. Credit:Arthritis & Rheumatology(2023). DOI: 10.1002/art.42450Juvenile dermatomyositis, a rare but often severe a

Updated on:May 29,2024

Fracture risk down with adherence to bisphosphonates

For patients with an osteoporotic fracture, adherence to bisphosphonate treatment is associated with reduced fracture risk; and for veterans with rheumatoid arthritis, non-adherence to bisphosphonate

Updated on: March 24,2024

Fracture risk down with adherence to bisphosphonates

For patients with an osteoporotic fracture, adherence to bisphosphonate treatment is associated with reduced fracture risk; and for veterans with rheumatoid arthritis, non-adherence to bisphosphonate

Updated on:March 24,2024

How does vaccination thwart pneumococcal infection? Animal model uncovers 'capture and kill' scenario

by Delthia Ricks , Medical XpressRepresentative IVM imaging of vaccine-activated capture of ST865 pneumococci in the liver sinusoids. Pneumococci, green; KCs, red; ECs, cyan; neutrophils, magenta. Cre

Updated on: March 07,2024

How does vaccination thwart pneumococcal infection? Animal model uncovers 'capture and kill' scenario

by Delthia Ricks , Medical XpressRepresentative IVM imaging of vaccine-activated capture of ST865 pneumococci in the liver sinusoids. Pneumococci, green; KCs, red; ECs, cyan; neutrophils, magenta. Cre

Updated on:March 07,2024

A protein's surprising role offers clues to limit graft-vs.-host disease

by Nicole Fawcett,University of MichiganFrom left, Hideaki Fujiwara, M.D., Ph.D.; Grace Chen, M.D., Ph.D.; and Pavan Reddy, M.D. Credit: University of Michigan Rogel Cancer CenterA protein that

Updated on: May 07,2024

A protein's surprising role offers clues to limit graft-vs.-host disease

by Nicole Fawcett,University of MichiganFrom left, Hideaki Fujiwara, M.D., Ph.D.; Grace Chen, M.D., Ph.D.; and Pavan Reddy, M.D. Credit: University of Michigan Rogel Cancer CenterA protein that

Updated on:May 07,2024

OCTAVE study reveals vaccine responses in patients with impaired immune systems

by University of GlasgowCredit: Pixabay/CC0 Public DomainThe OCTAVE study—a multi-center, UK-wide trial, led by the University of Glasgow and co-ordinated by the University of Birmingham's Ca

Updated on: April 20,2024

OCTAVE study reveals vaccine responses in patients with impaired immune systems

by University of GlasgowCredit: Pixabay/CC0 Public DomainThe OCTAVE study—a multi-center, UK-wide trial, led by the University of Glasgow and co-ordinated by the University of Birmingham's Ca

Updated on:April 20,2024

Is rheumatoid arthritis two different diseases?

by Public Library of ScienceCredit: CC0 Public DomainWhile disease activity improves over time for most rheumatoid arthritis (RA) patients, long-term outcomes only improve in RA patients with aut

Updated on: June 17,2024

Is rheumatoid arthritis two different diseases?

by Public Library of ScienceCredit: CC0 Public DomainWhile disease activity improves over time for most rheumatoid arthritis (RA) patients, long-term outcomes only improve in RA patients with aut

Updated on:June 17,2024