Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on: January 11,2025 0

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on:January 11,2025 0

New mechanism fueling brain metastasis discovered at Wistar

by The Wistar InstituteDr. Qing Chen of The Wistar Institute Credit: The Wistar InstituteScientists at The Wistar Institute described a novel mechanism through which astrocytes, the most abundant

Updated on: May 05,2024 16

New mechanism fueling brain metastasis discovered at Wistar

by The Wistar InstituteDr. Qing Chen of The Wistar Institute Credit: The Wistar InstituteScientists at The Wistar Institute described a novel mechanism through which astrocytes, the most abundant

Updated on:May 05,2024 16

New safety checklist aims to prevent side effects in patients with arthritis

by Line Rønn,Aarhus UniversityOverview of contraindications and warnings from EMA SmPC and FDA PI for biologic and targeted synthetic disease modifying antirheumatic drugs based on MedDRA system

Updated on: August 08,2024 0

New safety checklist aims to prevent side effects in patients with arthritis

by Line Rønn,Aarhus UniversityOverview of contraindications and warnings from EMA SmPC and FDA PI for biologic and targeted synthetic disease modifying antirheumatic drugs based on MedDRA system

Updated on:August 08,2024 0

Numerous jobs linked to increased risk of knee reconstruction

by University of SydneyExercises to avoid and treat osteoarthritis. Credit: Institute of Bone and Joint Research, University of SydneyKnee replacements are a huge burden on society and individual

Updated on: June 06,2024 3

Numerous jobs linked to increased risk of knee reconstruction

by University of SydneyExercises to avoid and treat osteoarthritis. Credit: Institute of Bone and Joint Research, University of SydneyKnee replacements are a huge burden on society and individual

Updated on:June 06,2024 3

Research suggests early life antibiotic increases asthma risk, providing clues to potential prevention of adult asthma

byMonash UniversityCredit: Pixabay/CC0 Public DomainEarly exposure to antibiotics can trigger long term susceptibility to asthma, according to new research from Monash University. Importantly, t

Updated on: July 17,2024 0

Research suggests early life antibiotic increases asthma risk, providing clues to potential prevention of adult asthma

byMonash UniversityCredit: Pixabay/CC0 Public DomainEarly exposure to antibiotics can trigger long term susceptibility to asthma, according to new research from Monash University. Importantly, t

Updated on:July 17,2024 0

Recurrent wheezing in children linked to 'silent' viral infections

by Josh Barney,University of VirginiaNearly a quarter of children with recurrent wheezing suffer from lung infections that present no symptoms and should be treated with antiviral medications, U

Updated on: August 08,2024 0

Recurrent wheezing in children linked to 'silent' viral infections

by Josh Barney,University of VirginiaNearly a quarter of children with recurrent wheezing suffer from lung infections that present no symptoms and should be treated with antiviral medications, U

Updated on:August 08,2024 0

Study reveals new role for inflammatory protein in fat tissue

byKarolinska InstitutetMicroscope image of fat cells. Credit: Kaisa HofwimmerA new studypublishedinNature Communicationsshows that the inflammatory protein IL-1β has an i

Updated on: October 30,2024 0

Study reveals new role for inflammatory protein in fat tissue

byKarolinska InstitutetMicroscope image of fat cells. Credit: Kaisa HofwimmerA new studypublishedinNature Communicationsshows that the inflammatory protein IL-1β has an i

Updated on:October 30,2024 0

New prediction model could help inform patients of their risks of having shoulder replacement surgery

byUniversity of OxfordCredit: Pixabay/CC0 Public DomainA new model to predict the risk of serious complications after shoulder replacement surgery has been developed in a collaboration between r

Updated on: August 08,2024 0

New prediction model could help inform patients of their risks of having shoulder replacement surgery

byUniversity of OxfordCredit: Pixabay/CC0 Public DomainA new model to predict the risk of serious complications after shoulder replacement surgery has been developed in a collaboration between r

Updated on:August 08,2024 0

Gene variant exacerbates inflammatory arthritis in mice

by University of Utah Health SciencesA swollen ankle joint with severe inflammatory arthritis. A build up of glycosaminoglycans (GAGs), long carbohydrate chains, is thought to contribute to sever

Updated on: May 26,2024 8

Gene variant exacerbates inflammatory arthritis in mice

by University of Utah Health SciencesA swollen ankle joint with severe inflammatory arthritis. A build up of glycosaminoglycans (GAGs), long carbohydrate chains, is thought to contribute to sever

Updated on:May 26,2024 8

Prevalence of multimorbidity up in rheumatoid arthritis

Patients with rheumatoid arthritis (RA) have an increased prevalence of multimorbidity, according to a study recently published inRMD Open.Cynthia S. Crowson, Ph.D., from the Mayo Clinic in Roch

Updated on: June 17,2024 5

Prevalence of multimorbidity up in rheumatoid arthritis

Patients with rheumatoid arthritis (RA) have an increased prevalence of multimorbidity, according to a study recently published inRMD Open.Cynthia S. Crowson, Ph.D., from the Mayo Clinic in Roch

Updated on:June 17,2024 5

Running, even in excess, doesn't lead to more osteoarthritis and hip replacements

by Dan Krotz,Lawrence Berkeley National LaboratoryCredit: Berkeley Lab photographer Roy Kaltschmidt(Medical Xpress)—Need another reason to dust off those running shoes in the back of the closet?

Updated on: June 06,2024 5

Running, even in excess, doesn't lead to more osteoarthritis and hip replacements

by Dan Krotz,Lawrence Berkeley National LaboratoryCredit: Berkeley Lab photographer Roy Kaltschmidt(Medical Xpress)—Need another reason to dust off those running shoes in the back of the closet?

Updated on:June 06,2024 5

Lupus, rheumatoid arthritis tied to higher risk for adverse obstetric, birth outcomes

by Lori SolomonWomen with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) and their infants experience higher rates of adverse obstetric and birth outcomes, according to a study publis

Updated on: June 15,2024 8

Lupus, rheumatoid arthritis tied to higher risk for adverse obstetric, birth outcomes

by Lori SolomonWomen with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) and their infants experience higher rates of adverse obstetric and birth outcomes, according to a study publis

Updated on:June 15,2024 8