New safety checklist aims to prevent side effects in patients with arthritis

by Line Rønn,Aarhus UniversityOverview of contraindications and warnings from EMA SmPC and FDA PI for biologic and targeted synthetic disease modifying antirheumatic drugs based on MedDRA system

Updated on: August 08,2024 0

New safety checklist aims to prevent side effects in patients with arthritis

by Line Rønn,Aarhus UniversityOverview of contraindications and warnings from EMA SmPC and FDA PI for biologic and targeted synthetic disease modifying antirheumatic drugs based on MedDRA system

Updated on:August 08,2024 0

FDA approves first interchangeable biosimilar for inflammatory diseases

(HealthDay)—The first interchangeable biosimilar product to Humira (adalimumab) was approved by the U.S. Food and Drug Administration on Oct. 15, the agency announced Monday.Cyltezo (adalimumab-adbm),

Updated on: June 17,2024 6

FDA approves first interchangeable biosimilar for inflammatory diseases

(HealthDay)—The first interchangeable biosimilar product to Humira (adalimumab) was approved by the U.S. Food and Drug Administration on Oct. 15, the agency announced Monday.Cyltezo (adalimumab-adbm),

Updated on:June 17,2024 6

Gene variant exacerbates inflammatory arthritis in mice

by University of Utah Health SciencesA swollen ankle joint with severe inflammatory arthritis. A build up of glycosaminoglycans (GAGs), long carbohydrate chains, is thought to contribute to sever

Updated on: May 26,2024 8

Gene variant exacerbates inflammatory arthritis in mice

by University of Utah Health SciencesA swollen ankle joint with severe inflammatory arthritis. A build up of glycosaminoglycans (GAGs), long carbohydrate chains, is thought to contribute to sever

Updated on:May 26,2024 8

Scientists discover two cellular defects appear to drive disease in lupus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine and Brigham and Women's Hospital scientists have discovered a molecular defect that promotes the pathologic im

Updated on: July 11,2024 0

Scientists discover two cellular defects appear to drive disease in lupus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine and Brigham and Women's Hospital scientists have discovered a molecular defect that promotes the pathologic im

Updated on:July 11,2024 0

Prevalence of multimorbidity up in rheumatoid arthritis

Patients with rheumatoid arthritis (RA) have an increased prevalence of multimorbidity, according to a study recently published inRMD Open.Cynthia S. Crowson, Ph.D., from the Mayo Clinic in Roch

Updated on: June 17,2024 5

Prevalence of multimorbidity up in rheumatoid arthritis

Patients with rheumatoid arthritis (RA) have an increased prevalence of multimorbidity, according to a study recently published inRMD Open.Cynthia S. Crowson, Ph.D., from the Mayo Clinic in Roch

Updated on:June 17,2024 5

Early age of menopause linked to seropositivity in RA

(HealthDay)—In women with early rheumatoid arthritis (RA), early age at menopause is associated with seropositivity, according to a study published in the May issue ofArthritis Care & Resear

Updated on: March 24,2024 11

Early age of menopause linked to seropositivity in RA

(HealthDay)—In women with early rheumatoid arthritis (RA), early age at menopause is associated with seropositivity, according to a study published in the May issue ofArthritis Care & Resear

Updated on:March 24,2024 11

New device monitors levels of inflammation-associated C-reactive protein in real time

byPolish Academy of SciencesGraphical abstract. Credit:ACS Sensors(2024). DOI: 10.1021/acssensors.4c00249As inflammation is the body's natural immune response to disease or infec

Updated on: September 02,2024 0

New device monitors levels of inflammation-associated C-reactive protein in real time

byPolish Academy of SciencesGraphical abstract. Credit:ACS Sensors(2024). DOI: 10.1021/acssensors.4c00249As inflammation is the body's natural immune response to disease or infec

Updated on:September 02,2024 0

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on: January 11,2025 0

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on:January 11,2025 0

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on: June 15,2024 4

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on:June 15,2024 4

CRISPR screen reveals loss of genes in interferon gamma receptor signaling pathway

by Massachusetts General HospitalGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0Researchers at Massachusetts General Hospital (MGH) have discovered that the interferon gamma recept

Updated on: April 13,2024 16

CRISPR screen reveals loss of genes in interferon gamma receptor signaling pathway

by Massachusetts General HospitalGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0Researchers at Massachusetts General Hospital (MGH) have discovered that the interferon gamma recept

Updated on:April 13,2024 16

Socioeconomic factors linked to persistently active rheumatoid arthritis

by Elana GotkineSocioeconomic factors and deprivation are associated with persistently active rheumatoid arthritis (pactiveRA), according to a study published online July 14 inRMD Open.Maryam Ad

Updated on: July 23,2024 0

Socioeconomic factors linked to persistently active rheumatoid arthritis

by Elana GotkineSocioeconomic factors and deprivation are associated with persistently active rheumatoid arthritis (pactiveRA), according to a study published online July 14 inRMD Open.Maryam Ad

Updated on:July 23,2024 0

Lupus, rheumatoid arthritis tied to higher risk for adverse obstetric, birth outcomes

by Lori SolomonWomen with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) and their infants experience higher rates of adverse obstetric and birth outcomes, according to a study publis

Updated on: June 15,2024 8

Lupus, rheumatoid arthritis tied to higher risk for adverse obstetric, birth outcomes

by Lori SolomonWomen with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) and their infants experience higher rates of adverse obstetric and birth outcomes, according to a study publis

Updated on:June 15,2024 8