Chromosomal loop signatures could identify poor drug response in arthritis

by University of GlasgowCredit: University of GlasgowChromosomal loop signatures found in blood samples obtained in early rheumatoid arthritis could identify patients that will not respond adequa

Updated on: April 17,2024

Chromosomal loop signatures could identify poor drug response in arthritis

by University of GlasgowCredit: University of GlasgowChromosomal loop signatures found in blood samples obtained in early rheumatoid arthritis could identify patients that will not respond adequa

Updated on:April 17,2024

Study finds antibody-associated vasculitis characteristics and treatments vary across lifespan

by American College of RheumatologyMedications ever received by patients with granulomatosis with polyangiitis and microscopic polyangiitis stratified by age at diagnosis. Credit: The Association

Updated on: May 08,2024

Study finds antibody-associated vasculitis characteristics and treatments vary across lifespan

by American College of RheumatologyMedications ever received by patients with granulomatosis with polyangiitis and microscopic polyangiitis stratified by age at diagnosis. Credit: The Association

Updated on:May 08,2024

Abatacept therapy offers promising results for treating juvenile dermatomyositis

by George Washington UniversityScreening, Trial Entry and Outcome. Credit:Arthritis & Rheumatology(2023). DOI: 10.1002/art.42450Juvenile dermatomyositis, a rare but often severe a

Updated on: May 29,2024

Abatacept therapy offers promising results for treating juvenile dermatomyositis

by George Washington UniversityScreening, Trial Entry and Outcome. Credit:Arthritis & Rheumatology(2023). DOI: 10.1002/art.42450Juvenile dermatomyositis, a rare but often severe a

Updated on:May 29,2024

Fracture risk down with adherence to bisphosphonates

For patients with an osteoporotic fracture, adherence to bisphosphonate treatment is associated with reduced fracture risk; and for veterans with rheumatoid arthritis, non-adherence to bisphosphonate

Updated on: March 24,2024

Fracture risk down with adherence to bisphosphonates

For patients with an osteoporotic fracture, adherence to bisphosphonate treatment is associated with reduced fracture risk; and for veterans with rheumatoid arthritis, non-adherence to bisphosphonate

Updated on:March 24,2024

A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on: May 07,2024

A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on:May 07,2024

Is rheumatoid arthritis two different diseases?

by Public Library of ScienceCredit: CC0 Public DomainWhile disease activity improves over time for most rheumatoid arthritis (RA) patients, long-term outcomes only improve in RA patients with aut

Updated on: June 17,2024

Is rheumatoid arthritis two different diseases?

by Public Library of ScienceCredit: CC0 Public DomainWhile disease activity improves over time for most rheumatoid arthritis (RA) patients, long-term outcomes only improve in RA patients with aut

Updated on:June 17,2024

Suppressing graft-versus-host disease using immunosuppressive iPS cell-derived regulatory T cells

by Kyoto UniversityGraphical abstract. Credit:Cell Stem Cell(2024). DOI: 10.1016/j.stem.2024.05.004A recent study by a team led by Professor Shin Kaneko successfully induced regulator

Updated on: June 15,2024

Suppressing graft-versus-host disease using immunosuppressive iPS cell-derived regulatory T cells

by Kyoto UniversityGraphical abstract. Credit:Cell Stem Cell(2024). DOI: 10.1016/j.stem.2024.05.004A recent study by a team led by Professor Shin Kaneko successfully induced regulator

Updated on:June 15,2024

OCTAVE study reveals vaccine responses in patients with impaired immune systems

by University of GlasgowCredit: Pixabay/CC0 Public DomainThe OCTAVE study—a multi-center, UK-wide trial, led by the University of Glasgow and co-ordinated by the University of Birmingham's Ca

Updated on: April 20,2024

OCTAVE study reveals vaccine responses in patients with impaired immune systems

by University of GlasgowCredit: Pixabay/CC0 Public DomainThe OCTAVE study—a multi-center, UK-wide trial, led by the University of Glasgow and co-ordinated by the University of Birmingham's Ca

Updated on:April 20,2024

How does vaccination thwart pneumococcal infection? Animal model uncovers 'capture and kill' scenario

by Delthia Ricks , Medical XpressRepresentative IVM imaging of vaccine-activated capture of ST865 pneumococci in the liver sinusoids. Pneumococci, green; KCs, red; ECs, cyan; neutrophils, magenta. Cre

Updated on: March 07,2024

How does vaccination thwart pneumococcal infection? Animal model uncovers 'capture and kill' scenario

by Delthia Ricks , Medical XpressRepresentative IVM imaging of vaccine-activated capture of ST865 pneumococci in the liver sinusoids. Pneumococci, green; KCs, red; ECs, cyan; neutrophils, magenta. Cre

Updated on:March 07,2024

MRI-guided Tx strategy not superior for rheumatoid arthritis

(HealthDay)—A magnetic resonance imaging (MRI)-guided treat-to-target strategy is not associated with improved disease activity remission rates for patients with rheumatoid arthritis (RA) in clinical

Updated on: May 08,2024

MRI-guided Tx strategy not superior for rheumatoid arthritis

(HealthDay)—A magnetic resonance imaging (MRI)-guided treat-to-target strategy is not associated with improved disease activity remission rates for patients with rheumatoid arthritis (RA) in clinical

Updated on:May 08,2024

Numerous jobs linked to increased risk of knee reconstruction

by University of SydneyExercises to avoid and treat osteoarthritis. Credit: Institute of Bone and Joint Research, University of SydneyKnee replacements are a huge burden on society and individual

Updated on: June 06,2024

Numerous jobs linked to increased risk of knee reconstruction

by University of SydneyExercises to avoid and treat osteoarthritis. Credit: Institute of Bone and Joint Research, University of SydneyKnee replacements are a huge burden on society and individual

Updated on:June 06,2024

Patients with rheumatic and musculoskeletal conditions vulnerable to long term opioid use

by British Medical JournalCredit: Unsplash/CC0 Public DomainPatients with rheumatic and musculoskeletal conditions are vulnerable to long term opioid use, with up to 1 in 3 of those with rheumato

Updated on: June 15,2024

Patients with rheumatic and musculoskeletal conditions vulnerable to long term opioid use

by British Medical JournalCredit: Unsplash/CC0 Public DomainPatients with rheumatic and musculoskeletal conditions are vulnerable to long term opioid use, with up to 1 in 3 of those with rheumato

Updated on:June 15,2024