A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on: May 07,2024

A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on:May 07,2024

A stealthy way to combat tumors

by Anne Trafton,Massachusetts Institute of TechnologyMIT researchers have identified a specialized subset of dendritic cells that help stimulate T cells to attack tumors. In this image, the blue

Updated on: May 07,2024

A stealthy way to combat tumors

by Anne Trafton,Massachusetts Institute of TechnologyMIT researchers have identified a specialized subset of dendritic cells that help stimulate T cells to attack tumors. In this image, the blue

Updated on:May 07,2024

Knee pain not linked with activity levels in adults with knee osteoarthritis

by WileyCredit: CC0 Public DomainKnee pain was not associated with daily walking levels in anArthritis Care & Researchstudy of individuals with mild-to-moderate, symptomatic knee

Updated on: April 17,2024

Knee pain not linked with activity levels in adults with knee osteoarthritis

by WileyCredit: CC0 Public DomainKnee pain was not associated with daily walking levels in anArthritis Care & Researchstudy of individuals with mild-to-moderate, symptomatic knee

Updated on:April 17,2024

Risk score predicts disease progression in patients with rheumatoid arthritis

by WileyCredit: Unsplash/CC0 Public DomainScientists have created a risk score based on thousands of genetic variants to determine the prognosis of individual patients with rheumatoid arthritis.I

Updated on: June 17,2024

Risk score predicts disease progression in patients with rheumatoid arthritis

by WileyCredit: Unsplash/CC0 Public DomainScientists have created a risk score based on thousands of genetic variants to determine the prognosis of individual patients with rheumatoid arthritis.I

Updated on:June 17,2024

Scientists discover new mechanism controlling T-cells in inflammation

by Melissa Rohman,Northwestern UniversityGraphical abstract. Credit:Immunity(2024). DOI: 10.1016/j.immuni.2024.08.008Northwestern Medicine scientists have discovered a new mechanism

Updated on: October 10,2024

Scientists discover new mechanism controlling T-cells in inflammation

by Melissa Rohman,Northwestern UniversityGraphical abstract. Credit:Immunity(2024). DOI: 10.1016/j.immuni.2024.08.008Northwestern Medicine scientists have discovered a new mechanism

Updated on:October 10,2024

Fracture risk down with adherence to bisphosphonates

For patients with an osteoporotic fracture, adherence to bisphosphonate treatment is associated with reduced fracture risk; and for veterans with rheumatoid arthritis, non-adherence to bisphosphonate

Updated on: March 24,2024

Fracture risk down with adherence to bisphosphonates

For patients with an osteoporotic fracture, adherence to bisphosphonate treatment is associated with reduced fracture risk; and for veterans with rheumatoid arthritis, non-adherence to bisphosphonate

Updated on:March 24,2024

Study upends understanding about joint injuries

by Cornell UniversityCredit: CC0 Public DomainAn injury to the anterior cruciate ligament (ACL) can lead to severe osteoarthritis in both animal and human patients. Now, a new interdisciplinary s

Updated on: March 28,2024

Study upends understanding about joint injuries

by Cornell UniversityCredit: CC0 Public DomainAn injury to the anterior cruciate ligament (ACL) can lead to severe osteoarthritis in both animal and human patients. Now, a new interdisciplinary s

Updated on:March 28,2024

Fatigue among arthritis sufferers relieved by physical activity and talking therapies

by University of AberdeenPrimary outcomes across follow-up points. Error bars show SD. CFS=Chalder Fatigue Scale. FSS=Fatigue Severity Scale. PEP=personalized exercise programs. CBA=cognitive beh

Updated on: May 23,2024

Fatigue among arthritis sufferers relieved by physical activity and talking therapies

by University of AberdeenPrimary outcomes across follow-up points. Error bars show SD. CFS=Chalder Fatigue Scale. FSS=Fatigue Severity Scale. PEP=personalized exercise programs. CBA=cognitive beh

Updated on:May 23,2024

Rheumatoid arthritis finding may lead to new inflammation blockers

by Sara Tiner,Mayo ClinicCredit: Unsplash/CC0 Public DomainMayo Clinic researchers have linked the T cell dysfunction seen in rheumatoid arthritis with a metabolic deficiency, reported in a new&

Updated on: May 29,2024

Rheumatoid arthritis finding may lead to new inflammation blockers

by Sara Tiner,Mayo ClinicCredit: Unsplash/CC0 Public DomainMayo Clinic researchers have linked the T cell dysfunction seen in rheumatoid arthritis with a metabolic deficiency, reported in a new&

Updated on:May 29,2024

One step closer to tailored treatment of severe rheumatic diseases

by Aarhus UniversityThe study leads us to hope that the immunological cells and inflammatory signalling molecules in the joint of each individual patient will be able to predict the most effectiv

Updated on: June 17,2024

One step closer to tailored treatment of severe rheumatic diseases

by Aarhus UniversityThe study leads us to hope that the immunological cells and inflammatory signalling molecules in the joint of each individual patient will be able to predict the most effectiv

Updated on:June 17,2024

NIH should create an Office of Autoimmune Disease Research, says new report

by National Academies of Sciences, Engineering, and MedicineCredit: Pixabay/CC0 Public DomainWhile the quantity and quality of research that the National Institutes of Health (NIH) conducts on autoimm

Updated on: May 05,2024

NIH should create an Office of Autoimmune Disease Research, says new report

by National Academies of Sciences, Engineering, and MedicineCredit: Pixabay/CC0 Public DomainWhile the quantity and quality of research that the National Institutes of Health (NIH) conducts on autoimm

Updated on:May 05,2024

Novel noninvasive molecular imaging for monitoring rheumatoid arthritis

by Society of Nuclear Medicine and Molecular ImagingComparison of Tc-99m tilmanocept radiopharmaceutical uptake on planar imaging in subjects with active RA (A: 200 μg tilmanocept / 10 mCi Tc-99m; B-C

Updated on: May 08,2024

Novel noninvasive molecular imaging for monitoring rheumatoid arthritis

by Society of Nuclear Medicine and Molecular ImagingComparison of Tc-99m tilmanocept radiopharmaceutical uptake on planar imaging in subjects with active RA (A: 200 μg tilmanocept / 10 mCi Tc-99m; B-C

Updated on:May 08,2024