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Immunology & Rheumatology
Focuses on rheumatic and immune diseases.
Sub Categories on Immunology & Rheumatology
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Gene variant exacerbates inflammatory arthritis in mice

Gene variant exacerbates inflammatory arthritis in mice

by University of Utah Health SciencesA swollen ankle joint with severe inflammatory arthritis. A build up of glycosaminoglycans (GAGs), long carbohydrate chains, is thought to contribute to sever

Gene variant exacerbates inflammatory arthritis in mice

by University of Utah Health SciencesA swollen ankle joint with severe inflammatory arthritis. A build up of glycosaminoglycans (GAGs), long carbohydrate chains, is thought to contribute to sever
How changing gut microbiota can affect lupus disease activity in mice

How changing gut microbiota can affect lupus disease activity in mice

by The Ohio State UniversityFigure 1. NZM2410 colonized with SFB exhibit intensified kidney disease with elevated immune-complex deposition. 10-week old mice were oral gavaged with fecal matter f

How changing gut microbiota can affect lupus disease activity in mice

by The Ohio State UniversityFigure 1. NZM2410 colonized with SFB exhibit intensified kidney disease with elevated immune-complex deposition. 10-week old mice were oral gavaged with fecal matter f
Prevalence of multimorbidity up in rheumatoid arthritis

Prevalence of multimorbidity up in rheumatoid arthritis

Patients with rheumatoid arthritis (RA) have an increased prevalence of multimorbidity, according to a study recently published inRMD Open.Cynthia S. Crowson, Ph.D., from the Mayo Clinic in Roch

Prevalence of multimorbidity up in rheumatoid arthritis

Patients with rheumatoid arthritis (RA) have an increased prevalence of multimorbidity, according to a study recently published inRMD Open.Cynthia S. Crowson, Ph.D., from the Mayo Clinic in Roch
Early age of menopause linked to seropositivity in RA

Early age of menopause linked to seropositivity in RA

(HealthDay)—In women with early rheumatoid arthritis (RA), early age at menopause is associated with seropositivity, according to a study published in the May issue ofArthritis Care & Resear

Early age of menopause linked to seropositivity in RA

(HealthDay)—In women with early rheumatoid arthritis (RA), early age at menopause is associated with seropositivity, according to a study published in the May issue ofArthritis Care & Resear
Running, even in excess, doesn't lead to more osteoarthritis and hip replacements

Running, even in excess, doesn't lead to more osteoarthritis and hip replacements

by Dan Krotz,Lawrence Berkeley National LaboratoryCredit: Berkeley Lab photographer Roy Kaltschmidt(Medical Xpress)—Need another reason to dust off those running shoes in the back of the closet?

Running, even in excess, doesn't lead to more osteoarthritis and hip replacements

by Dan Krotz,Lawrence Berkeley National LaboratoryCredit: Berkeley Lab photographer Roy Kaltschmidt(Medical Xpress)—Need another reason to dust off those running shoes in the back of the closet?
Patient-driven discovery reveals potential target for autoimmune diseases

Patient-driven discovery reveals potential target for autoimmune diseases

by Isabella Backman,Yale UniversityModel summarizing the function of PI3Kγ in antibody responses. Credit:Nature Immunology(2024). DOI: 10.1038/s41590-024-01890-1A medical mystery ser

Patient-driven discovery reveals potential target for autoimmune diseases

by Isabella Backman,Yale UniversityModel summarizing the function of PI3Kγ in antibody responses. Credit:Nature Immunology(2024). DOI: 10.1038/s41590-024-01890-1A medical mystery ser
Investigators discover unique immune cells in patients with checkpoint inhibitor-induced arthritis

Investigators discover unique immune cells in patients with checkpoint inhibitor-induced arthritis

by Hospital for Special SurgeryCredit: CC0 Public DomainSince doctors began treating cancer patients with immunotherapy drugs called checkpoint inhibitors nearly a decade ago, they have observed

Investigators discover unique immune cells in patients with checkpoint inhibitor-induced arthritis

by Hospital for Special SurgeryCredit: CC0 Public DomainSince doctors began treating cancer patients with immunotherapy drugs called checkpoint inhibitors nearly a decade ago, they have observed
Early and intensive treatment of rheumatoid arthritis reduces fatigue

Early and intensive treatment of rheumatoid arthritis reduces fatigue

by European League Against RheumatismCredit: CC0 Public DomainDisease-related, profound fatigue impairs the quality of life of many people with rheumatic and musculoskeletal diseases. A Belgian s

Early and intensive treatment of rheumatoid arthritis reduces fatigue

by European League Against RheumatismCredit: CC0 Public DomainDisease-related, profound fatigue impairs the quality of life of many people with rheumatic and musculoskeletal diseases. A Belgian s
Rheumatoid arthritis linked to a lower risk of type 2 diabetes

Rheumatoid arthritis linked to a lower risk of type 2 diabetes

by WileyCredit: CC0 Public DomainA recent analysis of a US commercial insurance database found that adults with rheumatoid arthritis had a lower risk of developing type 2 diabetes than other indi

Rheumatoid arthritis linked to a lower risk of type 2 diabetes

by WileyCredit: CC0 Public DomainA recent analysis of a US commercial insurance database found that adults with rheumatoid arthritis had a lower risk of developing type 2 diabetes than other indi
Fecal microbiota transplantation for active peripheral psoriatic arthritis shows no advantage

Fecal microbiota transplantation for active peripheral psoriatic arthritis shows no advantage

by European Alliance of Associations for RheumatologyCredit: CC0 Public DomainIn this proof-of-concept study, Maja Skov Kragsnaes and colleagues evaluated efficacy and safety of FMT in people with pso

Fecal microbiota transplantation for active peripheral psoriatic arthritis shows no advantage

by European Alliance of Associations for RheumatologyCredit: CC0 Public DomainIn this proof-of-concept study, Maja Skov Kragsnaes and colleagues evaluated efficacy and safety of FMT in people with pso
How intravenous immunoglobulin antibodies resolve joint inflammation in rheumatoid arthritis

How intravenous immunoglobulin antibodies resolve joint inflammation in rheumatoid arthritis

by Friedrich–Alexander University Erlangen–NurnbergGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.02.019Immunoglobulin G antibodies (IgB) play an important role

How intravenous immunoglobulin antibodies resolve joint inflammation in rheumatoid arthritis

by Friedrich–Alexander University Erlangen–NurnbergGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.02.019Immunoglobulin G antibodies (IgB) play an important role
Study establishes IL-24 as a critical factor for onset and progression of atopic dermatitis

Study establishes IL-24 as a critical factor for onset and progression of atopic dermatitis

by Higher Education PressIL-24, which is expressed in keratinocytes and induced by S. aureus infection, promotes atopic dermatitis-like inflammation by enhancing a type 2 immune response. Credit: Xinm

Study establishes IL-24 as a critical factor for onset and progression of atopic dermatitis

by Higher Education PressIL-24, which is expressed in keratinocytes and induced by S. aureus infection, promotes atopic dermatitis-like inflammation by enhancing a type 2 immune response. Credit: Xinm