HSPC-derived CAR T-cells capable of lasting engraftment

(HealthDay)—Hematopoietic stem/progenitor cell (HSPC)-derived chimeric antigen receptor (CAR) T-cells are capable of long-term engraftment in a model of HIV/AIDS, according to a study published online

Updated on: April 16,2024

HSPC-derived CAR T-cells capable of lasting engraftment

(HealthDay)—Hematopoietic stem/progenitor cell (HSPC)-derived chimeric antigen receptor (CAR) T-cells are capable of long-term engraftment in a model of HIV/AIDS, according to a study published online

Updated on:April 16,2024

A protein's surprising role offers clues to limit graft-vs.-host disease

by Nicole Fawcett,University of MichiganFrom left, Hideaki Fujiwara, M.D., Ph.D.; Grace Chen, M.D., Ph.D.; and Pavan Reddy, M.D. Credit: University of Michigan Rogel Cancer CenterA protein that

Updated on: May 07,2024

A protein's surprising role offers clues to limit graft-vs.-host disease

by Nicole Fawcett,University of MichiganFrom left, Hideaki Fujiwara, M.D., Ph.D.; Grace Chen, M.D., Ph.D.; and Pavan Reddy, M.D. Credit: University of Michigan Rogel Cancer CenterA protein that

Updated on:May 07,2024

One step closer to tailored treatment of severe rheumatic diseases

by Aarhus UniversityThe study leads us to hope that the immunological cells and inflammatory signalling molecules in the joint of each individual patient will be able to predict the most effectiv

Updated on: June 17,2024

One step closer to tailored treatment of severe rheumatic diseases

by Aarhus UniversityThe study leads us to hope that the immunological cells and inflammatory signalling molecules in the joint of each individual patient will be able to predict the most effectiv

Updated on:June 17,2024

Extra pounds linked to rheumatoid arthritis risk in women

Those who were overweight or obese were more likely to develop the painful disease, analysis showed.(HealthDay)—Overweight and obese women are at increased risk for rheumatoid arthritis, a new study s

Updated on: March 24,2024

Extra pounds linked to rheumatoid arthritis risk in women

Those who were overweight or obese were more likely to develop the painful disease, analysis showed.(HealthDay)—Overweight and obese women are at increased risk for rheumatoid arthritis, a new study s

Updated on:March 24,2024

How a COVID-19 infection spurs antibodies against common colds

by The Scripps Research InstituteResearchers analyzed the structures of antibodies (colored) from healthy donors as the molecules bound to the spike protein from common coronaviruses like OC43 (s

Updated on: April 10,2024

How a COVID-19 infection spurs antibodies against common colds

by The Scripps Research InstituteResearchers analyzed the structures of antibodies (colored) from healthy donors as the molecules bound to the spike protein from common coronaviruses like OC43 (s

Updated on:April 10,2024

A stealthy way to combat tumors

by Anne Trafton,Massachusetts Institute of TechnologyMIT researchers have identified a specialized subset of dendritic cells that help stimulate T cells to attack tumors. In this image, the blue

Updated on: May 07,2024

A stealthy way to combat tumors

by Anne Trafton,Massachusetts Institute of TechnologyMIT researchers have identified a specialized subset of dendritic cells that help stimulate T cells to attack tumors. In this image, the blue

Updated on:May 07,2024

Study aims to unravel the genetic causes of osteoarthritis

by Wellcome Trust Sanger InstituteA hip with osteoarthritis. In an X-ray of a healthy hip, the heads of the hip bone have smooth, evenly curved surfaces and there is a 'gap' between the h

Updated on: March 28,2024

Study aims to unravel the genetic causes of osteoarthritis

by Wellcome Trust Sanger InstituteA hip with osteoarthritis. In an X-ray of a healthy hip, the heads of the hip bone have smooth, evenly curved surfaces and there is a 'gap' between the h

Updated on:March 28,2024

The 'greying' of T cells: Scientists pinpoint metabolic pathway behind age-related immunity loss

by Harvard Medical SchoolCredit: CC0 Public DomainThe elderly suffer more serious complications from infections and benefit less from vaccination than the general population. Scientists have long

Updated on: May 06,2024

The 'greying' of T cells: Scientists pinpoint metabolic pathway behind age-related immunity loss

by Harvard Medical SchoolCredit: CC0 Public DomainThe elderly suffer more serious complications from infections and benefit less from vaccination than the general population. Scientists have long

Updated on:May 06,2024

How does vaccination thwart pneumococcal infection? Animal model uncovers 'capture and kill' scenario

by Delthia Ricks , Medical XpressRepresentative IVM imaging of vaccine-activated capture of ST865 pneumococci in the liver sinusoids. Pneumococci, green; KCs, red; ECs, cyan; neutrophils, magenta. Cre

Updated on: March 07,2024

How does vaccination thwart pneumococcal infection? Animal model uncovers 'capture and kill' scenario

by Delthia Ricks , Medical XpressRepresentative IVM imaging of vaccine-activated capture of ST865 pneumococci in the liver sinusoids. Pneumococci, green; KCs, red; ECs, cyan; neutrophils, magenta. Cre

Updated on:March 07,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on: April 16,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on:April 16,2024

T-cells: The superheroes in the battle against omicron

by Luke O'neill,The ConversationCredit: AI-generated imageOmicron is spreading rapidly throughout the world, with experts claiming that 40% of the global population will be infected within t

Updated on: May 07,2024

T-cells: The superheroes in the battle against omicron

by Luke O'neill,The ConversationCredit: AI-generated imageOmicron is spreading rapidly throughout the world, with experts claiming that 40% of the global population will be infected within t

Updated on:May 07,2024

Is rheumatoid arthritis two different diseases?

by Public Library of ScienceCredit: CC0 Public DomainWhile disease activity improves over time for most rheumatoid arthritis (RA) patients, long-term outcomes only improve in RA patients with aut

Updated on: June 17,2024

Is rheumatoid arthritis two different diseases?

by Public Library of ScienceCredit: CC0 Public DomainWhile disease activity improves over time for most rheumatoid arthritis (RA) patients, long-term outcomes only improve in RA patients with aut

Updated on:June 17,2024