A protein's surprising role offers clues to limit graft-vs.-host disease

by Nicole Fawcett,University of MichiganFrom left, Hideaki Fujiwara, M.D., Ph.D.; Grace Chen, M.D., Ph.D.; and Pavan Reddy, M.D. Credit: University of Michigan Rogel Cancer CenterA protein that

Updated on: May 07,2024

A protein's surprising role offers clues to limit graft-vs.-host disease

by Nicole Fawcett,University of MichiganFrom left, Hideaki Fujiwara, M.D., Ph.D.; Grace Chen, M.D., Ph.D.; and Pavan Reddy, M.D. Credit: University of Michigan Rogel Cancer CenterA protein that

Updated on:May 07,2024

Drug shows promise to treat diet-induced osteoarthritis

by Queensland University of TechnologyCredit: CC0 Public DomainQUT scientists have found that a drug derived from omega-3 fatty acids can reduce osteoarthritis inflammation that's been caused

Updated on: April 17,2024

Drug shows promise to treat diet-induced osteoarthritis

by Queensland University of TechnologyCredit: CC0 Public DomainQUT scientists have found that a drug derived from omega-3 fatty acids can reduce osteoarthritis inflammation that's been caused

Updated on:April 17,2024

One step closer to tailored treatment of severe rheumatic diseases

by Aarhus UniversityThe study leads us to hope that the immunological cells and inflammatory signalling molecules in the joint of each individual patient will be able to predict the most effectiv

Updated on: June 17,2024

One step closer to tailored treatment of severe rheumatic diseases

by Aarhus UniversityThe study leads us to hope that the immunological cells and inflammatory signalling molecules in the joint of each individual patient will be able to predict the most effectiv

Updated on:June 17,2024

Is rheumatoid arthritis two different diseases?

by Public Library of ScienceCredit: CC0 Public DomainWhile disease activity improves over time for most rheumatoid arthritis (RA) patients, long-term outcomes only improve in RA patients with aut

Updated on: June 17,2024

Is rheumatoid arthritis two different diseases?

by Public Library of ScienceCredit: CC0 Public DomainWhile disease activity improves over time for most rheumatoid arthritis (RA) patients, long-term outcomes only improve in RA patients with aut

Updated on:June 17,2024

NIH should create an Office of Autoimmune Disease Research, says new report

by National Academies of Sciences, Engineering, and MedicineCredit: Pixabay/CC0 Public DomainWhile the quantity and quality of research that the National Institutes of Health (NIH) conducts on autoimm

Updated on: May 05,2024

NIH should create an Office of Autoimmune Disease Research, says new report

by National Academies of Sciences, Engineering, and MedicineCredit: Pixabay/CC0 Public DomainWhile the quantity and quality of research that the National Institutes of Health (NIH) conducts on autoimm

Updated on:May 05,2024

T cells: Vesicles strengthen immune response

by Ludwig Maximilian University of MunichMFG-E8-eGFP detects PS+ apoptotic and PS+ EV-decorated cells in vivo. Credit: Proceedings of the National Academy of Sciences (2023). DOI: 10.1073/pnas.22

Updated on: May 05,2024

T cells: Vesicles strengthen immune response

by Ludwig Maximilian University of MunichMFG-E8-eGFP detects PS+ apoptotic and PS+ EV-decorated cells in vivo. Credit: Proceedings of the National Academy of Sciences (2023). DOI: 10.1073/pnas.22

Updated on:May 05,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on: April 16,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on:April 16,2024

How a COVID-19 infection spurs antibodies against common colds

by The Scripps Research InstituteResearchers analyzed the structures of antibodies (colored) from healthy donors as the molecules bound to the spike protein from common coronaviruses like OC43 (s

Updated on: April 10,2024

How a COVID-19 infection spurs antibodies against common colds

by The Scripps Research InstituteResearchers analyzed the structures of antibodies (colored) from healthy donors as the molecules bound to the spike protein from common coronaviruses like OC43 (s

Updated on:April 10,2024

A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on: May 07,2024

A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on:May 07,2024

Study aims to unravel the genetic causes of osteoarthritis

by Wellcome Trust Sanger InstituteA hip with osteoarthritis. In an X-ray of a healthy hip, the heads of the hip bone have smooth, evenly curved surfaces and there is a 'gap' between the h

Updated on: March 28,2024

Study aims to unravel the genetic causes of osteoarthritis

by Wellcome Trust Sanger InstituteA hip with osteoarthritis. In an X-ray of a healthy hip, the heads of the hip bone have smooth, evenly curved surfaces and there is a 'gap' between the h

Updated on:March 28,2024

Risk score predicts disease progression in patients with rheumatoid arthritis

by WileyCredit: Unsplash/CC0 Public DomainScientists have created a risk score based on thousands of genetic variants to determine the prognosis of individual patients with rheumatoid arthritis.I

Updated on: June 17,2024

Risk score predicts disease progression in patients with rheumatoid arthritis

by WileyCredit: Unsplash/CC0 Public DomainScientists have created a risk score based on thousands of genetic variants to determine the prognosis of individual patients with rheumatoid arthritis.I

Updated on:June 17,2024

Extra pounds linked to rheumatoid arthritis risk in women

Those who were overweight or obese were more likely to develop the painful disease, analysis showed.(HealthDay)—Overweight and obese women are at increased risk for rheumatoid arthritis, a new study s

Updated on: March 24,2024

Extra pounds linked to rheumatoid arthritis risk in women

Those who were overweight or obese were more likely to develop the painful disease, analysis showed.(HealthDay)—Overweight and obese women are at increased risk for rheumatoid arthritis, a new study s

Updated on:March 24,2024