Meta-analysis quantifies lifestyle factors accounting for RA incidence

(HealthDay)—Nearly one-third of rheumatoid arthritis (RA) incidence is attributed to smoking, excess body mass index, and low alcohol consumption, according to a study published online Jan. 26 in&nbsp

Updated on: May 08,2024

Meta-analysis quantifies lifestyle factors accounting for RA incidence

(HealthDay)—Nearly one-third of rheumatoid arthritis (RA) incidence is attributed to smoking, excess body mass index, and low alcohol consumption, according to a study published online Jan. 26 in&nbsp

Updated on:May 08,2024

A new open-access portal for human immunology data and tools

by Rachel Tompa,Allen Institute for Brain ScienceTEA-seq single panel cell type data from Human Immune System Explorer. Credit: Zach Thomson/Allen InstituteResearchers at the Allen Institute for

Updated on: May 05,2024

A new open-access portal for human immunology data and tools

by Rachel Tompa,Allen Institute for Brain ScienceTEA-seq single panel cell type data from Human Immune System Explorer. Credit: Zach Thomson/Allen InstituteResearchers at the Allen Institute for

Updated on:May 05,2024

Researchers find new way to curb asthma attacks

by Dennis ThompsonA protein that shuts down immune cells in the lungs could be key to a new treatment for asthma attacks, a new report says.The naturally occurringprotein, called Piezo1, prevent

Updated on: March 27,2024

Researchers find new way to curb asthma attacks

by Dennis ThompsonA protein that shuts down immune cells in the lungs could be key to a new treatment for asthma attacks, a new report says.The naturally occurringprotein, called Piezo1, prevent

Updated on:March 27,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on: April 16,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on:April 16,2024

Knee pain not linked with activity levels in adults with knee osteoarthritis

by WileyCredit: CC0 Public DomainKnee pain was not associated with daily walking levels in anArthritis Care & Researchstudy of individuals with mild-to-moderate, symptomatic knee

Updated on: April 17,2024

Knee pain not linked with activity levels in adults with knee osteoarthritis

by WileyCredit: CC0 Public DomainKnee pain was not associated with daily walking levels in anArthritis Care & Researchstudy of individuals with mild-to-moderate, symptomatic knee

Updated on:April 17,2024

Fracture risk down with adherence to bisphosphonates

For patients with an osteoporotic fracture, adherence to bisphosphonate treatment is associated with reduced fracture risk; and for veterans with rheumatoid arthritis, non-adherence to bisphosphonate

Updated on: March 24,2024

Fracture risk down with adherence to bisphosphonates

For patients with an osteoporotic fracture, adherence to bisphosphonate treatment is associated with reduced fracture risk; and for veterans with rheumatoid arthritis, non-adherence to bisphosphonate

Updated on:March 24,2024

Chromosomal loop signatures could identify poor drug response in arthritis

by University of GlasgowCredit: University of GlasgowChromosomal loop signatures found in blood samples obtained in early rheumatoid arthritis could identify patients that will not respond adequa

Updated on: April 17,2024

Chromosomal loop signatures could identify poor drug response in arthritis

by University of GlasgowCredit: University of GlasgowChromosomal loop signatures found in blood samples obtained in early rheumatoid arthritis could identify patients that will not respond adequa

Updated on:April 17,2024

Study aims to unravel the genetic causes of osteoarthritis

by Wellcome Trust Sanger InstituteA hip with osteoarthritis. In an X-ray of a healthy hip, the heads of the hip bone have smooth, evenly curved surfaces and there is a 'gap' between the h

Updated on: March 28,2024

Study aims to unravel the genetic causes of osteoarthritis

by Wellcome Trust Sanger InstituteA hip with osteoarthritis. In an X-ray of a healthy hip, the heads of the hip bone have smooth, evenly curved surfaces and there is a 'gap' between the h

Updated on:March 28,2024

The secret lives of T cells: They derive energy from a master regulator that has been poorly understood, until now

by Delthia Ricks , Medical XpressIn vitro modeling of Teff STAT5 responses. (A) WT CD4+ T cells were cultured with or without blocking anti-mouse IL-2/IL-2R antibodies and/or human IL-2. Flow cytometr

Updated on: May 06,2024

The secret lives of T cells: They derive energy from a master regulator that has been poorly understood, until now

by Delthia Ricks , Medical XpressIn vitro modeling of Teff STAT5 responses. (A) WT CD4+ T cells were cultured with or without blocking anti-mouse IL-2/IL-2R antibodies and/or human IL-2. Flow cytometr

Updated on:May 06,2024

A common metabolite may help treat autoimmune diseases

by Hokkaido UniversityIn mice models with adoptive transfer experimental autoimmune encephalomyelitis, treatment with itaconate (right) greatly ameliorates the effects of the disease, compared to

Updated on: May 08,2024

A common metabolite may help treat autoimmune diseases

by Hokkaido UniversityIn mice models with adoptive transfer experimental autoimmune encephalomyelitis, treatment with itaconate (right) greatly ameliorates the effects of the disease, compared to

Updated on:May 08,2024

How a COVID-19 infection spurs antibodies against common colds

by The Scripps Research InstituteResearchers analyzed the structures of antibodies (colored) from healthy donors as the molecules bound to the spike protein from common coronaviruses like OC43 (s

Updated on: April 10,2024

How a COVID-19 infection spurs antibodies against common colds

by The Scripps Research InstituteResearchers analyzed the structures of antibodies (colored) from healthy donors as the molecules bound to the spike protein from common coronaviruses like OC43 (s

Updated on:April 10,2024

Suppressing graft-versus-host disease using immunosuppressive iPS cell-derived regulatory T cells

by Kyoto UniversityGraphical abstract. Credit:Cell Stem Cell(2024). DOI: 10.1016/j.stem.2024.05.004A recent study by a team led by Professor Shin Kaneko successfully induced regulator

Updated on: June 15,2024

Suppressing graft-versus-host disease using immunosuppressive iPS cell-derived regulatory T cells

by Kyoto UniversityGraphical abstract. Credit:Cell Stem Cell(2024). DOI: 10.1016/j.stem.2024.05.004A recent study by a team led by Professor Shin Kaneko successfully induced regulator

Updated on:June 15,2024