m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on: April 16,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on:April 16,2024

Minority patients with rheumatic diseases have worse COVID-19 outcomes

by American College of RheumatologyCredit: CC0 Public DomainNew research at ACR Convergence, the American College of Rheumatology's annual meeting, reveals that people of color with rheumatic

Updated on: May 29,2024

Minority patients with rheumatic diseases have worse COVID-19 outcomes

by American College of RheumatologyCredit: CC0 Public DomainNew research at ACR Convergence, the American College of Rheumatology's annual meeting, reveals that people of color with rheumatic

Updated on:May 29,2024

How a COVID-19 infection spurs antibodies against common colds

by The Scripps Research InstituteResearchers analyzed the structures of antibodies (colored) from healthy donors as the molecules bound to the spike protein from common coronaviruses like OC43 (s

Updated on: April 10,2024

How a COVID-19 infection spurs antibodies against common colds

by The Scripps Research InstituteResearchers analyzed the structures of antibodies (colored) from healthy donors as the molecules bound to the spike protein from common coronaviruses like OC43 (s

Updated on:April 10,2024

Ointment containing DNA molecules can combat allergic contact dermatitis

byUniversity of BonnFluorescence microscopic imaging of the skin treated with the aptamer cream: - The aptamers (here marked in pink) were applied to the top layer of the skin in the form of an

Updated on: July 06,2024

Ointment containing DNA molecules can combat allergic contact dermatitis

byUniversity of BonnFluorescence microscopic imaging of the skin treated with the aptamer cream: - The aptamers (here marked in pink) were applied to the top layer of the skin in the form of an

Updated on:July 06,2024

Chromosomal loop signatures could identify poor drug response in arthritis

by University of GlasgowCredit: University of GlasgowChromosomal loop signatures found in blood samples obtained in early rheumatoid arthritis could identify patients that will not respond adequa

Updated on: April 17,2024

Chromosomal loop signatures could identify poor drug response in arthritis

by University of GlasgowCredit: University of GlasgowChromosomal loop signatures found in blood samples obtained in early rheumatoid arthritis could identify patients that will not respond adequa

Updated on:April 17,2024

Study aims to unravel the genetic causes of osteoarthritis

by Wellcome Trust Sanger InstituteA hip with osteoarthritis. In an X-ray of a healthy hip, the heads of the hip bone have smooth, evenly curved surfaces and there is a 'gap' between the h

Updated on: March 28,2024

Study aims to unravel the genetic causes of osteoarthritis

by Wellcome Trust Sanger InstituteA hip with osteoarthritis. In an X-ray of a healthy hip, the heads of the hip bone have smooth, evenly curved surfaces and there is a 'gap' between the h

Updated on:March 28,2024

Mood disorders common with rheumatoid arthritis

(HealthDay)—Depression and anxiety are common in patients with rheumatoid arthritis (RA), according to a study published online Jan. 6 in theInternational Journal of Rheumatic Diseases.Wanruchad

Updated on: July 02,2024

Mood disorders common with rheumatoid arthritis

(HealthDay)—Depression and anxiety are common in patients with rheumatoid arthritis (RA), according to a study published online Jan. 6 in theInternational Journal of Rheumatic Diseases.Wanruchad

Updated on:July 02,2024

Rheumatoid arthritis linked to a lower risk of type 2 diabetes

by WileyCredit: CC0 Public DomainA recent analysis of a US commercial insurance database found that adults with rheumatoid arthritis had a lower risk of developing type 2 diabetes than other indi

Updated on: June 17,2024

Rheumatoid arthritis linked to a lower risk of type 2 diabetes

by WileyCredit: CC0 Public DomainA recent analysis of a US commercial insurance database found that adults with rheumatoid arthritis had a lower risk of developing type 2 diabetes than other indi

Updated on:June 17,2024

Researchers find new way to curb asthma attacks

by Dennis ThompsonA protein that shuts down immune cells in the lungs could be key to a new treatment for asthma attacks, a new report says.The naturally occurringprotein, called Piezo1, prevent

Updated on: March 27,2024

Researchers find new way to curb asthma attacks

by Dennis ThompsonA protein that shuts down immune cells in the lungs could be key to a new treatment for asthma attacks, a new report says.The naturally occurringprotein, called Piezo1, prevent

Updated on:March 27,2024

Rheumatoid arthritis finding may lead to new inflammation blockers

by Sara Tiner,Mayo ClinicCredit: Unsplash/CC0 Public DomainMayo Clinic researchers have linked the T cell dysfunction seen in rheumatoid arthritis with a metabolic deficiency, reported in a new&

Updated on: May 29,2024

Rheumatoid arthritis finding may lead to new inflammation blockers

by Sara Tiner,Mayo ClinicCredit: Unsplash/CC0 Public DomainMayo Clinic researchers have linked the T cell dysfunction seen in rheumatoid arthritis with a metabolic deficiency, reported in a new&

Updated on:May 29,2024

An antibody-drug combo to combat cancer

by Tokyo Medical and Dental UniversityCredit: Tokyo Medical and Dental UniversityLeukemias are debilitating cancers of the hematopoietic or blood-forming cells of the bone marrow. Now, researchers at

Updated on: May 05,2024

An antibody-drug combo to combat cancer

by Tokyo Medical and Dental UniversityCredit: Tokyo Medical and Dental UniversityLeukemias are debilitating cancers of the hematopoietic or blood-forming cells of the bone marrow. Now, researchers at

Updated on:May 05,2024

Survival improving after hip and knee replacement

(HealthDay)—Short-term survival after elective total hip (THR) and total knee replacement (TKR) has greatly improved since the early 1990s, even though comorbidities have increased, according to a stu

Updated on: April 08,2024

Survival improving after hip and knee replacement

(HealthDay)—Short-term survival after elective total hip (THR) and total knee replacement (TKR) has greatly improved since the early 1990s, even though comorbidities have increased, according to a stu

Updated on:April 08,2024