Epigenetics is of critical importance in autoimmune-related skin diseases, says study

by Higher Education PressCredit: Lingyu Gao, Qianjin LuThe central dogma proposed that genetic information predominantly transfers from DNA to RNA during gene expression to make a functional product p

Updated on: March 27,2024 0

Epigenetics is of critical importance in autoimmune-related skin diseases, says study

by Higher Education PressCredit: Lingyu Gao, Qianjin LuThe central dogma proposed that genetic information predominantly transfers from DNA to RNA during gene expression to make a functional product p

Updated on:March 27,2024 0

Skyrizi approved for psoriatic arthritis

(HealthDay)—The U.S. Food and Drug Administration has expanded the approval of Skyrizi (risankizumab-rzaa) to treatment of adults with active psoriatic arthritis, the manufacturer announced Friday.The

Updated on: May 26,2024 6

Skyrizi approved for psoriatic arthritis

(HealthDay)—The U.S. Food and Drug Administration has expanded the approval of Skyrizi (risankizumab-rzaa) to treatment of adults with active psoriatic arthritis, the manufacturer announced Friday.The

Updated on:May 26,2024 6

Gene variant links trigger finger and carpal tunnel syndrome

by University of OxfordAssociation between trigger finger and carpal tunnel syndrome. Data from UK Biobank. (A) Overlap between trigger finger and carpal tunnel syndrome in UK Biobank, annotated

Updated on: June 06,2024 6

Gene variant links trigger finger and carpal tunnel syndrome

by University of OxfordAssociation between trigger finger and carpal tunnel syndrome. Data from UK Biobank. (A) Overlap between trigger finger and carpal tunnel syndrome in UK Biobank, annotated

Updated on:June 06,2024 6

Review highlights the challenges and recent advances in targeted therapies for lupus nephritis

by Cactus CommunicationsSLE involves abnormal activation of both innate and adaptive immune responses, leading to systemic immune dysregulation and renal impairment. The complement system's dysfun

Updated on: January 26,2024 13

Review highlights the challenges and recent advances in targeted therapies for lupus nephritis

by Cactus CommunicationsSLE involves abnormal activation of both innate and adaptive immune responses, leading to systemic immune dysregulation and renal impairment. The complement system's dysfun

Updated on:January 26,2024 13

The double face of RNase as a treatment for systemic autoimmune diseases

by Osaka UniversityThe RNA-degrading enzyme enhances the function of immune complexes formed by autoantibodies against Ro/SSA and La/SSB antigens. Credit: Ryota Naito et al. JCI Insight 2023Syste

Updated on: April 22,2024 20

The double face of RNase as a treatment for systemic autoimmune diseases

by Osaka UniversityThe RNA-degrading enzyme enhances the function of immune complexes formed by autoantibodies against Ro/SSA and La/SSB antigens. Credit: Ryota Naito et al. JCI Insight 2023Syste

Updated on:April 22,2024 20

New genetic risk factors for rheumatoid arthritis revealed by analysis of multiple ancestry groups

by RIKENEnrichment of high PIP variants within open chromatin regions of 18 blood cell populations was analyzed by gchromVAR software. The horizontal dashed line indicates Bonferroni corrected P

Updated on: May 26,2024 6

New genetic risk factors for rheumatoid arthritis revealed by analysis of multiple ancestry groups

by RIKENEnrichment of high PIP variants within open chromatin regions of 18 blood cell populations was analyzed by gchromVAR software. The horizontal dashed line indicates Bonferroni corrected P

Updated on:May 26,2024 6

Scientists solve 18-year-old mystery and find the once-elusive source of a critical T cell population

by Delthia Ricks , Medical XpressPresence of Tcf7+CD8+T cells during the primary response to infection. (A) Experimental schematic: Naïve P14 cells (CD45.2) were transferred into congenica

Updated on: January 26,2024 17

Scientists solve 18-year-old mystery and find the once-elusive source of a critical T cell population

by Delthia Ricks , Medical XpressPresence of Tcf7+CD8+T cells during the primary response to infection. (A) Experimental schematic: Naïve P14 cells (CD45.2) were transferred into congenica

Updated on:January 26,2024 17

This gross mixture has big benefits for the study of bacteria

byUniversity of MichiganDetermining the bottleneck of infection forP. mirabilisduring UTI. (A–C) CBA/J mice were transurethrally inoculated with 107CFU. The inoculum contained

Updated on: January 25,2024 17

This gross mixture has big benefits for the study of bacteria

byUniversity of MichiganDetermining the bottleneck of infection forP. mirabilisduring UTI. (A–C) CBA/J mice were transurethrally inoculated with 107CFU. The inoculum contained

Updated on:January 25,2024 17

Study reveals way to predict side-effect risk from common immune suppressant medication

by University of NottinghamMethotrexate (MTX) is an anti-metabolite most commonly used in chemotherapy and immunosuppressant in auto-immune diseases. Credit: University of NottinghamA major new s

Updated on: January 29,2024 13

Study reveals way to predict side-effect risk from common immune suppressant medication

by University of NottinghamMethotrexate (MTX) is an anti-metabolite most commonly used in chemotherapy and immunosuppressant in auto-immune diseases. Credit: University of NottinghamA major new s

Updated on:January 29,2024 13

Research reveals risk factors for poor asthma control in children

by Don Bell,University of AlbertaCredit: Pixabay/CC0 Public DomainA recent University of Alberta study is shedding more light on how perinatal health and early life events are related to asthma

Updated on: January 28,2024 12

Research reveals risk factors for poor asthma control in children

by Don Bell,University of AlbertaCredit: Pixabay/CC0 Public DomainA recent University of Alberta study is shedding more light on how perinatal health and early life events are related to asthma

Updated on:January 28,2024 12

'Cell food' gives insight into T cell metabolism

by Anna Megdell,University of Michigan“A T cell's specific identity and function are ruled by metabolic pathways, so each type of T cell's inner workings are distinct,” Hanna Hong explai

Updated on: April 01,2024 18

'Cell food' gives insight into T cell metabolism

by Anna Megdell,University of Michigan“A T cell's specific identity and function are ruled by metabolic pathways, so each type of T cell's inner workings are distinct,” Hanna Hong explai

Updated on:April 01,2024 18

Vaccination guards against certain bacterial infections and slows the spread of superbugs in populations

by Delthia Ricks , Medical XpressStreptococcus pneumoniae. Credit: CDC/Dr. M.S. MitchellVaccines that boost immunity against bacteria can protect the immunized from contracting drug-resistant infectio

Updated on: March 05,2024 16

Vaccination guards against certain bacterial infections and slows the spread of superbugs in populations

by Delthia Ricks , Medical XpressStreptococcus pneumoniae. Credit: CDC/Dr. M.S. MitchellVaccines that boost immunity against bacteria can protect the immunized from contracting drug-resistant infectio

Updated on:March 05,2024 16