Urate transporter structures reveal the mechanism behind important drug target for gout

bySt. Jude Children's Research HospitalCryo-EM structures of human URAT1 in different functional states. Credit:Cell Research(2024). DOI: 10.1038/s41422-024-01023-1Scientists at

Updated on: September 15,2024

Urate transporter structures reveal the mechanism behind important drug target for gout

bySt. Jude Children's Research HospitalCryo-EM structures of human URAT1 in different functional states. Credit:Cell Research(2024). DOI: 10.1038/s41422-024-01023-1Scientists at

Updated on:September 15,2024

Alcohol consumption tied to less disease activity with rheumatoid arthritis

by Lori SolomonThere is an inverse relationship between alcohol consumption and disease activity in people with rheumatoid arthritis, according to a study published online Jan. 11 inArthritis &a

Updated on: April 07,2024

Alcohol consumption tied to less disease activity with rheumatoid arthritis

by Lori SolomonThere is an inverse relationship between alcohol consumption and disease activity in people with rheumatoid arthritis, according to a study published online Jan. 11 inArthritis &a

Updated on:April 07,2024

CRISPR screen identifies new anti-inflammatory drug target

by Vanderbilt University Medical CenterCredit: CC0 Public DomainA metabolic enzyme that has been studied in cancer biology and is important for T cell function may offer a new target for anti-inf

Updated on: April 12,2024

CRISPR screen identifies new anti-inflammatory drug target

by Vanderbilt University Medical CenterCredit: CC0 Public DomainA metabolic enzyme that has been studied in cancer biology and is important for T cell function may offer a new target for anti-inf

Updated on:April 12,2024

Socioeconomic factors may not predict rheumatoid arthritis disease activity

by Lori SolomonThe impact of socioeconomic factors on disease activity in rheumatoid arthritis (RA) varies by academic or safety net hospital setting, according to a studypublishedonline O

Updated on: December 09,2024

Socioeconomic factors may not predict rheumatoid arthritis disease activity

by Lori SolomonThe impact of socioeconomic factors on disease activity in rheumatoid arthritis (RA) varies by academic or safety net hospital setting, according to a studypublishedonline O

Updated on:December 09,2024

Potential treatment for rare autoimmune disorder could be adapted from CAR-T therapy, suggests clinical trial

by National Institutes of HealthColorized scanning electron micrograph of a T lymphocyte (also known as a T cell) (blue). Credit: NIAIDEvidence from a small-scale clinical trial suggests that a v

Updated on: May 08,2024

Potential treatment for rare autoimmune disorder could be adapted from CAR-T therapy, suggests clinical trial

by National Institutes of HealthColorized scanning electron micrograph of a T lymphocyte (also known as a T cell) (blue). Credit: NIAIDEvidence from a small-scale clinical trial suggests that a v

Updated on:May 08,2024

7.6 percent of global population had osteoarthritis in 2020

by Elana GotkineThe global burden of osteoarthritis has increased since 1990 and is projected to continue increasing, according to a study published online Aug. 21 inThe Lancet Rheumatology.Jaim

Updated on: May 29,2024

7.6 percent of global population had osteoarthritis in 2020

by Elana GotkineThe global burden of osteoarthritis has increased since 1990 and is projected to continue increasing, according to a study published online Aug. 21 inThe Lancet Rheumatology.Jaim

Updated on:May 29,2024

Better than a pill: Team to develop new arthritis treatment via silk

by Erika Ebsworth-Goold,Washington University School of Medicine in St. LouisA team of researchers from Washington University in St. Louis will use silk micro-particles, like the ones pictured h

Updated on: June 26,2024

Better than a pill: Team to develop new arthritis treatment via silk

by Erika Ebsworth-Goold,Washington University School of Medicine in St. LouisA team of researchers from Washington University in St. Louis will use silk micro-particles, like the ones pictured h

Updated on:June 26,2024

Spring, summer births linked to development of pollinosis

by Elana GotkineSpring and summer births are associated with development of pollinosis and summer births are associated with house dust mite (HDM) sensitization, according to a study published in the

Updated on: March 02,2024

Spring, summer births linked to development of pollinosis

by Elana GotkineSpring and summer births are associated with development of pollinosis and summer births are associated with house dust mite (HDM) sensitization, according to a study published in the

Updated on:March 02,2024

Can severe weather changes make allergies worse?

by Kaylee Dusang,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainAlthough allergies are normally associated with the spring and fall, it may feel like allergy season never left this w

Updated on: March 06,2024

Can severe weather changes make allergies worse?

by Kaylee Dusang,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainAlthough allergies are normally associated with the spring and fall, it may feel like allergy season never left this w

Updated on:March 06,2024

Ultra-low dose rituximab controls disease activity for most rheumatoid arthritis patients in new study

by American College of RheumatologyCredit: CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that in one study

Updated on: March 28,2024

Ultra-low dose rituximab controls disease activity for most rheumatoid arthritis patients in new study

by American College of RheumatologyCredit: CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that in one study

Updated on:March 28,2024

Older siblings and childhood tonsil removal linked to heightened risk of inflammatory arthritis

byBritish Medical JournalCredit: Pixabay/CC0 Public DomainHaving older siblings and childhood tonsil removal are linked to a heightened risk of ankylosing spondylitis, a type of chronic inflamma

Updated on: January 29,2024

Older siblings and childhood tonsil removal linked to heightened risk of inflammatory arthritis

byBritish Medical JournalCredit: Pixabay/CC0 Public DomainHaving older siblings and childhood tonsil removal are linked to a heightened risk of ankylosing spondylitis, a type of chronic inflamma

Updated on:January 29,2024

The most typical symptoms for common allergies

by Meredith MorckelMaybe you can't weed your garden without sneezing. Perhaps your eyes start watering when you clean your home. Did your skin begin itching last night during dinner?You may have a

Updated on: March 05,2024

The most typical symptoms for common allergies

by Meredith MorckelMaybe you can't weed your garden without sneezing. Perhaps your eyes start watering when you clean your home. Did your skin begin itching last night during dinner?You may have a

Updated on:March 05,2024