Potential treatment for rare autoimmune disorder could be adapted from CAR-T therapy, suggests clinical trial

by National Institutes of HealthColorized scanning electron micrograph of a T lymphocyte (also known as a T cell) (blue). Credit: NIAIDEvidence from a small-scale clinical trial suggests that a v

Updated on: May 08,2024

Potential treatment for rare autoimmune disorder could be adapted from CAR-T therapy, suggests clinical trial

by National Institutes of HealthColorized scanning electron micrograph of a T lymphocyte (also known as a T cell) (blue). Credit: NIAIDEvidence from a small-scale clinical trial suggests that a v

Updated on:May 08,2024

Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells

byScience China PressDuring viral infection, total m6A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T c

Updated on: January 26,2024

Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells

byScience China PressDuring viral infection, total m6A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T c

Updated on:January 26,2024

MAIT cells can be tuned to fight different pathogens via their metabolism, leading to new therapeutic strategies

by La Jolla Institute for ImmunologyCredit: Pixabay/CC0 Public DomainA population of unconventional white blood cells has recently captured the attention of immunologists and clinicians alike. Un

Updated on: April 20,2024

MAIT cells can be tuned to fight different pathogens via their metabolism, leading to new therapeutic strategies

by La Jolla Institute for ImmunologyCredit: Pixabay/CC0 Public DomainA population of unconventional white blood cells has recently captured the attention of immunologists and clinicians alike. Un

Updated on:April 20,2024

Ultra-low dose rituximab controls disease activity for most rheumatoid arthritis patients in new study

by American College of RheumatologyCredit: CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that in one study

Updated on: March 28,2024

Ultra-low dose rituximab controls disease activity for most rheumatoid arthritis patients in new study

by American College of RheumatologyCredit: CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that in one study

Updated on:March 28,2024

Few studies include photos of patients with psoriasis, finds review

by University of GothenburgCredit: Pixabay/CC0 Public DomainVery few patients with psoriasis are depicted in scientific articles—only a fraction of those included in the research are represented

Updated on: January 28,2024

Few studies include photos of patients with psoriasis, finds review

by University of GothenburgCredit: Pixabay/CC0 Public DomainVery few patients with psoriasis are depicted in scientific articles—only a fraction of those included in the research are represented

Updated on:January 28,2024

CRISPR reveals the secret life of antimicrobial peptides

by Ecole Polytechnique Federale de LausanneFruit flies with mutated antimicrobial peptides (red eyes) let bacteria (green fluorescence) grow out of control, while wild-type flies (with normal ant

Updated on: April 12,2024

CRISPR reveals the secret life of antimicrobial peptides

by Ecole Polytechnique Federale de LausanneFruit flies with mutated antimicrobial peptides (red eyes) let bacteria (green fluorescence) grow out of control, while wild-type flies (with normal ant

Updated on:April 12,2024

RNA as a future cure for hereditary diseases

by Fabio Bergamin,ETH ZurichOnly a handful of genetic diseases can be treated with drugs (symbolic image). One of several therapeutic approaches is based on RNA molecules. Credit: Science Photo

Updated on: April 22,2024

RNA as a future cure for hereditary diseases

by Fabio Bergamin,ETH ZurichOnly a handful of genetic diseases can be treated with drugs (symbolic image). One of several therapeutic approaches is based on RNA molecules. Credit: Science Photo

Updated on:April 22,2024

This gross mixture has big benefits for the study of bacteria

byUniversity of MichiganDetermining the bottleneck of infection forP. mirabilisduring UTI. (A–C) CBA/J mice were transurethrally inoculated with 107CFU. The inoculum contained

Updated on: January 25,2024

This gross mixture has big benefits for the study of bacteria

byUniversity of MichiganDetermining the bottleneck of infection forP. mirabilisduring UTI. (A–C) CBA/J mice were transurethrally inoculated with 107CFU. The inoculum contained

Updated on:January 25,2024

Understanding allergies

byRush University Medical CenterCredit: CC0 Public DomainDo you blow your nose and rub your itchy eyes more than usual in the spring? Chances are you have hay fever, also called allergic rhiniti

Updated on: March 04,2024

Understanding allergies

byRush University Medical CenterCredit: CC0 Public DomainDo you blow your nose and rub your itchy eyes more than usual in the spring? Chances are you have hay fever, also called allergic rhiniti

Updated on:March 04,2024

Forty percent of people with peanut allergies can eat tree nuts but choose not to

by American College of Allergy, Asthma, and ImmunologyCredit: CC0 Public DomainA new article inAnnals of Allergy, Asthma and Immunology, the scientific journal of the American College of Al

Updated on: April 02,2024

Forty percent of people with peanut allergies can eat tree nuts but choose not to

by American College of Allergy, Asthma, and ImmunologyCredit: CC0 Public DomainA new article inAnnals of Allergy, Asthma and Immunology, the scientific journal of the American College of Al

Updated on:April 02,2024

New pill could prevent anaphylaxis in people with food, drug allergies

by Northwestern UniversityCredit: CC0 Public DomainFor someone with a food or drug allergy, the risk of life-threatening anaphylactic shock lurks around every corner. A new Northwestern Medicine

Updated on: March 25,2024

New pill could prevent anaphylaxis in people with food, drug allergies

by Northwestern UniversityCredit: CC0 Public DomainFor someone with a food or drug allergy, the risk of life-threatening anaphylactic shock lurks around every corner. A new Northwestern Medicine

Updated on:March 25,2024

Holding mycophenolate mofetil for 10 days or more may improve COVID-19 vaccine response

by American College of RheumatologyAnti-spike antibody response following two dose SARS-CoV_2 vaccine dose in RMD, stratified by peri-vaccination mycophenolate hold duration. Credit: Increased Du

Updated on: May 13,2024

Holding mycophenolate mofetil for 10 days or more may improve COVID-19 vaccine response

by American College of RheumatologyAnti-spike antibody response following two dose SARS-CoV_2 vaccine dose in RMD, stratified by peri-vaccination mycophenolate hold duration. Credit: Increased Du

Updated on:May 13,2024