Potential treatment for rare autoimmune disorder could be adapted from CAR-T therapy, suggests clinical trial

by National Institutes of HealthColorized scanning electron micrograph of a T lymphocyte (also known as a T cell) (blue). Credit: NIAIDEvidence from a small-scale clinical trial suggests that a v

Updated on: May 08,2024 6

Potential treatment for rare autoimmune disorder could be adapted from CAR-T therapy, suggests clinical trial

by National Institutes of HealthColorized scanning electron micrograph of a T lymphocyte (also known as a T cell) (blue). Credit: NIAIDEvidence from a small-scale clinical trial suggests that a v

Updated on:May 08,2024 6

40 percent of adolescents with food allergies experience frequent anaphylactic episodes

by Murdoch Childrens Research InstituteCredit: Murdoch Childrens Research InstituteA new study by researchers from the Murdoch Children's Research Institute (MCRI) has shown that 40 percent o

Updated on: April 02,2024 17

40 percent of adolescents with food allergies experience frequent anaphylactic episodes

by Murdoch Childrens Research InstituteCredit: Murdoch Childrens Research InstituteA new study by researchers from the Murdoch Children's Research Institute (MCRI) has shown that 40 percent o

Updated on:April 02,2024 17

B cells gone bad could be the culprit in rheumatoid arthritis

by Laurie Fickman,University of HoustonBiomolecular researcher Navin Varadarajan anticipates that his data will serve as a foundation for investigating multiple hypotheses on the roles of B cell

Updated on: April 08,2024 14

B cells gone bad could be the culprit in rheumatoid arthritis

by Laurie Fickman,University of HoustonBiomolecular researcher Navin Varadarajan anticipates that his data will serve as a foundation for investigating multiple hypotheses on the roles of B cell

Updated on:April 08,2024 14

Man vaccinated for COVID 217 times reports no side effects: scientists

Credit: Maksim Goncharenok from PexelsA German man who deliberately got vaccinated for COVID-19 a whopping 217 times did not report any side effects from his many jabs, according to researchers studyi

Updated on: March 19,2024 20

Man vaccinated for COVID 217 times reports no side effects: scientists

Credit: Maksim Goncharenok from PexelsA German man who deliberately got vaccinated for COVID-19 a whopping 217 times did not report any side effects from his many jabs, according to researchers studyi

Updated on:March 19,2024 20

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

Updated on: April 20,2024 20

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

Updated on:April 20,2024 20

FDA wants more data on first needle-free antidote for severe allergic reactions

by Denise MannIn a surprising move, the U.S. Food and Drug Administration (FDA) has opted not to approve a needle-free alternative to the EpiPen for emergency treatment of severe allergic reactions.Ap

Updated on: January 27,2024 12

FDA wants more data on first needle-free antidote for severe allergic reactions

by Denise MannIn a surprising move, the U.S. Food and Drug Administration (FDA) has opted not to approve a needle-free alternative to the EpiPen for emergency treatment of severe allergic reactions.Ap

Updated on:January 27,2024 12

ATP from sensory neuron-interneuron crosstalk is key to spreading inflammation in rheumatoid arthritis

by Hokkaido UniversityThe inflammation signal (IL-6 amplifier) in the affected joint (L) causes the secretion of ATP that transmits a signal through the spinal cord (DRG, L5), which in turn trigg

Updated on: June 06,2024 4

ATP from sensory neuron-interneuron crosstalk is key to spreading inflammation in rheumatoid arthritis

by Hokkaido UniversityThe inflammation signal (IL-6 amplifier) in the affected joint (L) causes the secretion of ATP that transmits a signal through the spinal cord (DRG, L5), which in turn trigg

Updated on:June 06,2024 4

Gut Microbiome Changes as Early Indicators of Rheumatoid Arthritis Development

The intricate relationship between the gut microbiome and rheumatoid arthritis (RA) has become a significant area of research, with recent studies providing valuable insights into how gut bacteria might influence the onset and progression of this chronic

Updated on: November 15,2024 0

Gut Microbiome Changes as Early Indicators of Rheumatoid Arthritis Development

The intricate relationship between the gut microbiome and rheumatoid arthritis (RA) has become a significant area of research, with recent studies providing valuable insights into how gut bacteria might influence the onset and progression of this chronic

Updated on:November 15,2024 0

Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells

byScience China PressDuring viral infection, total m6A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T c

Updated on: January 26,2024 19

Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells

byScience China PressDuring viral infection, total m6A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T c

Updated on:January 26,2024 19

Study uncovers novel mechanisms behind food allergies

by Melissa Rohman,Northwestern UniversityCredit:Mucosal Immunology(2023). DOI: 10.1016/j.mucimm.2023.12.001A recent Northwestern Medicine study has shed light on the mechanisms of a

Updated on: March 19,2024 18

Study uncovers novel mechanisms behind food allergies

by Melissa Rohman,Northwestern UniversityCredit:Mucosal Immunology(2023). DOI: 10.1016/j.mucimm.2023.12.001A recent Northwestern Medicine study has shed light on the mechanisms of a

Updated on:March 19,2024 18

CAR T cell therapies may lead to reactivation of childhood viral infections

by Justin Jackson , Medical XpressPetabase-scale analysis of viral nucleic acids reveals that HHV-6 is reactivated in human T cells. a, Schematic of life cycles of endogenous human viruses. Viruses ca

Updated on: April 09,2024 10

CAR T cell therapies may lead to reactivation of childhood viral infections

by Justin Jackson , Medical XpressPetabase-scale analysis of viral nucleic acids reveals that HHV-6 is reactivated in human T cells. a, Schematic of life cycles of endogenous human viruses. Viruses ca

Updated on:April 09,2024 10

Key steps could reduces cases and deaths from rheumatic heart disease in the African Union

by Brigham and Women's HospitalCredit: Unsplash/CC0 Public DomainRheumatic heart disease (RHD) remains a major cause of cardiovascular disease in Africa, even as acute rheumatic fever and RHD

Updated on: June 01,2024 7

Key steps could reduces cases and deaths from rheumatic heart disease in the African Union

by Brigham and Women's HospitalCredit: Unsplash/CC0 Public DomainRheumatic heart disease (RHD) remains a major cause of cardiovascular disease in Africa, even as acute rheumatic fever and RHD

Updated on:June 01,2024 7