Ultra-low dose rituximab controls disease activity for most rheumatoid arthritis patients in new study

by American College of RheumatologyCredit: CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that in one study

Updated on: March 28,2024 17

Ultra-low dose rituximab controls disease activity for most rheumatoid arthritis patients in new study

by American College of RheumatologyCredit: CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that in one study

Updated on:March 28,2024 17

Lithium may protect against cartilage decline in osteoarthritis

(HealthDay)—Lithium reduces catabolic events in interleukin-1 β (IL-1β)-treated human articular chondrocytes and protects against cartilage degradation in IL-1β-treated mouse knee joints, according to

Updated on: March 24,2024 15

Lithium may protect against cartilage decline in osteoarthritis

(HealthDay)—Lithium reduces catabolic events in interleukin-1 β (IL-1β)-treated human articular chondrocytes and protects against cartilage degradation in IL-1β-treated mouse knee joints, according to

Updated on:March 24,2024 15

The double face of RNase as a treatment for systemic autoimmune diseases

by Osaka UniversityThe RNA-degrading enzyme enhances the function of immune complexes formed by autoantibodies against Ro/SSA and La/SSB antigens. Credit: Ryota Naito et al. JCI Insight 2023Syste

Updated on: April 22,2024 20

The double face of RNase as a treatment for systemic autoimmune diseases

by Osaka UniversityThe RNA-degrading enzyme enhances the function of immune complexes formed by autoantibodies against Ro/SSA and La/SSB antigens. Credit: Ryota Naito et al. JCI Insight 2023Syste

Updated on:April 22,2024 20

Scientists use blood test to track gene expression in the brain

by Kayt Sukel,Rice UniversityScan of mouse hippocampus and cortex, where the red signal derives from immunostaining for the synthetic marker developed by the Szablowski lab and the blue from the

Updated on: April 23,2024 0

Scientists use blood test to track gene expression in the brain

by Kayt Sukel,Rice UniversityScan of mouse hippocampus and cortex, where the red signal derives from immunostaining for the synthetic marker developed by the Szablowski lab and the blue from the

Updated on:April 23,2024 0

Revised ACR/EULAR rheumatoid arthritis remission criteria released

by European Alliance of Associations for Rheumatology (EULAR)Rates of rheumatoid arthritis (RA) disease remission according to modified Boolean classifications, using a patient global assessment (PtGA

Updated on: May 23,2024 4

Revised ACR/EULAR rheumatoid arthritis remission criteria released

by European Alliance of Associations for Rheumatology (EULAR)Rates of rheumatoid arthritis (RA) disease remission according to modified Boolean classifications, using a patient global assessment (PtGA

Updated on:May 23,2024 4

Discriminatory redlining practices in the 1930s associated with present-day rates of ED visits due to asthma

by LancetCredit: CC0 Public DomainCurrent rates of emergency department visits due to asthma are around 2.4 times higher in areas that were redlined—deprioritised for mortgage investment—in the 1

Updated on: April 02,2024 20

Discriminatory redlining practices in the 1930s associated with present-day rates of ED visits due to asthma

by LancetCredit: CC0 Public DomainCurrent rates of emergency department visits due to asthma are around 2.4 times higher in areas that were redlined—deprioritised for mortgage investment—in the 1

Updated on:April 02,2024 20

Could oral contraceptives help ease rheumatoid arthritis?

by Steven Reinberg, Healthday ReporterOnly association was seen, and older women shouldn't take the pill to treat symptoms, experts say.(HealthDay)—Oral contraceptives—also known as birth control

Updated on: March 24,2024 19

Could oral contraceptives help ease rheumatoid arthritis?

by Steven Reinberg, Healthday ReporterOnly association was seen, and older women shouldn't take the pill to treat symptoms, experts say.(HealthDay)—Oral contraceptives—also known as birth control

Updated on:March 24,2024 19

Evolutionary origin of mysterious immune system molecule in humans revealed

by Ashley WennersHerron,Pennsylvania State UniversityThe Joining chain shares three characteristics with the CXCL chemokine genes, including the same number of exons, which encode the protein, a

Updated on: April 22,2024 0

Evolutionary origin of mysterious immune system molecule in humans revealed

by Ashley WennersHerron,Pennsylvania State UniversityThe Joining chain shares three characteristics with the CXCL chemokine genes, including the same number of exons, which encode the protein, a

Updated on:April 22,2024 0

Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on: March 07,2024 18

Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on:March 07,2024 18

CRISPR study reveals new immune system regulators

by Wellcome Trust Sanger InstituteCRISPR-associated protein Cas9 (white) from Staphylococcus aureus based on Protein Database ID 5AXW. Credit: Thomas Splettstoesser (Wikipedia, CC BY-SA 4.0)Scien

Updated on: April 13,2024 20

CRISPR study reveals new immune system regulators

by Wellcome Trust Sanger InstituteCRISPR-associated protein Cas9 (white) from Staphylococcus aureus based on Protein Database ID 5AXW. Credit: Thomas Splettstoesser (Wikipedia, CC BY-SA 4.0)Scien

Updated on:April 13,2024 20

Groundbreaking study reveals clues to predict mortality in rare VEXAS syndrome

by American College of RheumatologyHematopoietic precursor cells: promyelocyte in the center, two metamyelocytes next to it and band cells from a bone marrow aspirate. Credit: Bobjgalindo/Wikiped

Updated on: May 23,2024 4

Groundbreaking study reveals clues to predict mortality in rare VEXAS syndrome

by American College of RheumatologyHematopoietic precursor cells: promyelocyte in the center, two metamyelocytes next to it and band cells from a bone marrow aspirate. Credit: Bobjgalindo/Wikiped

Updated on:May 23,2024 4

Eyes serve as immunological barrier in fight against brain pathogens, finds study

by Yale University10x VISIUM Spatial sequencing of the mouse globe and optic nerve. Mouse eyes were processed using traditional FFPE-based histology preparation. Samples were processed using the

Updated on: March 07,2024 15

Eyes serve as immunological barrier in fight against brain pathogens, finds study

by Yale University10x VISIUM Spatial sequencing of the mouse globe and optic nerve. Mouse eyes were processed using traditional FFPE-based histology preparation. Samples were processed using the

Updated on:March 07,2024 15