CAR T-cell immunotherapy rids woman of tough-to-treat lupus

by Amy Norton(HealthDay)—In a first, researchers have used genetically tweaked immune system cells to send a woman's severe lupus into remission.The treatment—called CAR T-cell therapy—is already

Updated on: April 09,2024

CAR T-cell immunotherapy rids woman of tough-to-treat lupus

by Amy Norton(HealthDay)—In a first, researchers have used genetically tweaked immune system cells to send a woman's severe lupus into remission.The treatment—called CAR T-cell therapy—is already

Updated on:April 09,2024

Study offers new insights into how immune cells recognize their enemies

by Gunnar Bartsch,Julius-Maximilians-Universität WürzburgPAg induced Vγ9Vδ2 T cell activation by BTN3A-BTN2A1 composite ligand. Credit:Nature Communications(2023). DOI: 10.1038/s4146

Updated on: January 26,2024

Study offers new insights into how immune cells recognize their enemies

by Gunnar Bartsch,Julius-Maximilians-Universität WürzburgPAg induced Vγ9Vδ2 T cell activation by BTN3A-BTN2A1 composite ligand. Credit:Nature Communications(2023). DOI: 10.1038/s4146

Updated on:January 26,2024

Treatment effect of tofacitinib, adalimumab compared in RA

by Elana GotkineFor adults with rheumatoid arthritis (RA), there is a modest reduction in the mean Disease Activity Score in 28 joints using C-reactive protein (DAS28-CRP) at three months for patients

Updated on: June 26,2024

Treatment effect of tofacitinib, adalimumab compared in RA

by Elana GotkineFor adults with rheumatoid arthritis (RA), there is a modest reduction in the mean Disease Activity Score in 28 joints using C-reactive protein (DAS28-CRP) at three months for patients

Updated on:June 26,2024

FDA approves new treatment for dust mite allergies

(HealthDay)—A new treatment for dust mite allergies has won approval from the U.S. Food and Drug Administration.Odactra is a year-round, once-a-day tablet that's dissolved under the tongue. It&#39

Updated on: April 15,2024

FDA approves new treatment for dust mite allergies

(HealthDay)—A new treatment for dust mite allergies has won approval from the U.S. Food and Drug Administration.Odactra is a year-round, once-a-day tablet that's dissolved under the tongue. It&#39

Updated on:April 15,2024

Study finds opioids double risk of venous thromboembolism in rheumatoid arthritis patients

by American College of RheumatologyRisk of outcomes (HR, 95% CI) with opioid initiation compared to NSAID initiation after adjustment for propensity score weights and imbalanced covariables (CVD

Updated on: May 13,2024

Study finds opioids double risk of venous thromboembolism in rheumatoid arthritis patients

by American College of RheumatologyRisk of outcomes (HR, 95% CI) with opioid initiation compared to NSAID initiation after adjustment for propensity score weights and imbalanced covariables (CVD

Updated on:May 13,2024

Curbing blood cancers by teaching immune cells to kill mutant stem cells

by Nancy Fliesler,Children's Hospital BostonROS and TLR3 signaling mediates the "eat-me" and "don't eat me" signals that determine stem cell clonal selection by macro

Updated on: October 24,2024

Curbing blood cancers by teaching immune cells to kill mutant stem cells

by Nancy Fliesler,Children's Hospital BostonROS and TLR3 signaling mediates the "eat-me" and "don't eat me" signals that determine stem cell clonal selection by macro

Updated on:October 24,2024

Trial shows timing matters when adding immunotherapy to chemoradiation for limited-stage small cell lung cancer

byAmerican Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainPeople with limited-stage small cell lung cancer may benefit from adding immunotherapy to chemoradiation, but not if bot

Updated on: October 26,2024

Trial shows timing matters when adding immunotherapy to chemoradiation for limited-stage small cell lung cancer

byAmerican Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainPeople with limited-stage small cell lung cancer may benefit from adding immunotherapy to chemoradiation, but not if bot

Updated on:October 26,2024

Teens with chronic conditions face challenges and risks when they age out of pediatric rheumatology care

by Michelle Batthish and Stephanie Garner,The ConversationCredit: AI-generated imageLiving with severeinflammatory arthritisor any other serious condition of the joints, bones and mu

Updated on: May 19,2024

Teens with chronic conditions face challenges and risks when they age out of pediatric rheumatology care

by Michelle Batthish and Stephanie Garner,The ConversationCredit: AI-generated imageLiving with severeinflammatory arthritisor any other serious condition of the joints, bones and mu

Updated on:May 19,2024

Scientists pioneer immunotherapy technique for autoimmune diseases

byMayo ClinicMSCs are transduced to express CAR and maintain stem-like features following transduction and stimulation. Credit:Nature Biomedical Engineering(2024). DOI: 10.1038/s4155

Updated on: April 06,2024

Scientists pioneer immunotherapy technique for autoimmune diseases

byMayo ClinicMSCs are transduced to express CAR and maintain stem-like features following transduction and stimulation. Credit:Nature Biomedical Engineering(2024). DOI: 10.1038/s4155

Updated on:April 06,2024

Successful murine model of dermatomyositis reveals underlying immune system involvement

byTokyo Medical and Dental UniversityAutoimmunity to MDA5, CD4 T cells reactive MDA5, works as 'Seed', and inducible factors like as virus infection and poly (I:C) treatment induce type

Updated on: April 28,2024

Successful murine model of dermatomyositis reveals underlying immune system involvement

byTokyo Medical and Dental UniversityAutoimmunity to MDA5, CD4 T cells reactive MDA5, works as 'Seed', and inducible factors like as virus infection and poly (I:C) treatment induce type

Updated on:April 28,2024

Repurposing tocilizumab in scleroderma patients may prevent early lung disease

by Jordyn Imhoff,University of MichiganCredit: CC0 Public DomainResearch led by Michigan Medicine's Scleroderma Program and published in Arthritis & Rheumatology found that tocilizumab,

Updated on: April 07,2024

Repurposing tocilizumab in scleroderma patients may prevent early lung disease

by Jordyn Imhoff,University of MichiganCredit: CC0 Public DomainResearch led by Michigan Medicine's Scleroderma Program and published in Arthritis & Rheumatology found that tocilizumab,

Updated on:April 07,2024

Ultra-low dose rituximab controls disease activity for most rheumatoid arthritis patients in new study

by American College of RheumatologyCredit: CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that in one study

Updated on: March 28,2024

Ultra-low dose rituximab controls disease activity for most rheumatoid arthritis patients in new study

by American College of RheumatologyCredit: CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that in one study

Updated on:March 28,2024