CAR T-cell immunotherapy rids woman of tough-to-treat lupus

by Amy Norton(HealthDay)—In a first, researchers have used genetically tweaked immune system cells to send a woman's severe lupus into remission.The treatment—called CAR T-cell therapy—is already

Updated on: April 09,2024 17

CAR T-cell immunotherapy rids woman of tough-to-treat lupus

by Amy Norton(HealthDay)—In a first, researchers have used genetically tweaked immune system cells to send a woman's severe lupus into remission.The treatment—called CAR T-cell therapy—is already

Updated on:April 09,2024 17

Study offers new insights into how immune cells recognize their enemies

by Gunnar Bartsch,Julius-Maximilians-Universität WürzburgPAg induced Vγ9Vδ2 T cell activation by BTN3A-BTN2A1 composite ligand. Credit:Nature Communications(2023). DOI: 10.1038/s4146

Updated on: January 26,2024 12

Study offers new insights into how immune cells recognize their enemies

by Gunnar Bartsch,Julius-Maximilians-Universität WürzburgPAg induced Vγ9Vδ2 T cell activation by BTN3A-BTN2A1 composite ligand. Credit:Nature Communications(2023). DOI: 10.1038/s4146

Updated on:January 26,2024 12

Trial shows timing matters when adding immunotherapy to chemoradiation for limited-stage small cell lung cancer

byAmerican Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainPeople with limited-stage small cell lung cancer may benefit from adding immunotherapy to chemoradiation, but not if bot

Updated on: October 26,2024 0

Trial shows timing matters when adding immunotherapy to chemoradiation for limited-stage small cell lung cancer

byAmerican Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainPeople with limited-stage small cell lung cancer may benefit from adding immunotherapy to chemoradiation, but not if bot

Updated on:October 26,2024 0

Successful murine model of dermatomyositis reveals underlying immune system involvement

byTokyo Medical and Dental UniversityAutoimmunity to MDA5, CD4 T cells reactive MDA5, works as 'Seed', and inducible factors like as virus infection and poly (I:C) treatment induce type

Updated on: April 28,2024 0

Successful murine model of dermatomyositis reveals underlying immune system involvement

byTokyo Medical and Dental UniversityAutoimmunity to MDA5, CD4 T cells reactive MDA5, works as 'Seed', and inducible factors like as virus infection and poly (I:C) treatment induce type

Updated on:April 28,2024 0

How mutation of the APC gene disrupts lymphocyte migration in colon cancer

by Pasteur InstituteMigrating human T lymphocytes revealing a broad protrusion at the leading edge and long adhesive protrusions at the rear. Image obtained by confocal fluorescence microscopy: f

Updated on: April 08,2024 19

How mutation of the APC gene disrupts lymphocyte migration in colon cancer

by Pasteur InstituteMigrating human T lymphocytes revealing a broad protrusion at the leading edge and long adhesive protrusions at the rear. Image obtained by confocal fluorescence microscopy: f

Updated on:April 08,2024 19

A fresh look at joint inflammation in rheumatoid arthritis patients

by Trinity College DublinCredit: Unsplash/CC0 Public DomainResearchers at Trinity are providing fresh insights into joint inflammation in patients with rheumatoid arthritis (RA). The condition cu

Updated on: June 11,2024 5

A fresh look at joint inflammation in rheumatoid arthritis patients

by Trinity College DublinCredit: Unsplash/CC0 Public DomainResearchers at Trinity are providing fresh insights into joint inflammation in patients with rheumatoid arthritis (RA). The condition cu

Updated on:June 11,2024 5

Smoking shown to have long-term effects on the immune system

by Pasteur InstituteCredit: CC0 Public DomainLike other factors such as age, sex, and genetics, smoking has a major impact on immune responses. This is the finding recently made by a team of scie

Updated on: March 07,2024 14

Smoking shown to have long-term effects on the immune system

by Pasteur InstituteCredit: CC0 Public DomainLike other factors such as age, sex, and genetics, smoking has a major impact on immune responses. This is the finding recently made by a team of scie

Updated on:March 07,2024 14

Rejuvenation of aging cells helps to cure osteoarthritis through gene therapy

by Chinese Academy of SciencesCBX4 maintains nucleolar homeostasis, alleviates senescence and osteoarthritis. Credit: IOZAging is a risk factor for the development of osteoarthritis (OA), a chron

Updated on: May 13,2024 3

Rejuvenation of aging cells helps to cure osteoarthritis through gene therapy

by Chinese Academy of SciencesCBX4 maintains nucleolar homeostasis, alleviates senescence and osteoarthritis. Credit: IOZAging is a risk factor for the development of osteoarthritis (OA), a chron

Updated on:May 13,2024 3

Researchers describe how birch pollen affects immune cells

by Jan Grabowski, Zentrum für Experimentelle und Klinische InfektionsforschungAPE exposure induces transcriptional changes in moDC. (A) IL-12p70 content in supernatants of moDC stimulated with 100 ng/

Updated on: March 05,2024 14

Researchers describe how birch pollen affects immune cells

by Jan Grabowski, Zentrum für Experimentelle und Klinische InfektionsforschungAPE exposure induces transcriptional changes in moDC. (A) IL-12p70 content in supernatants of moDC stimulated with 100 ng/

Updated on:March 05,2024 14

COVID-19 booster immunity lasts much longer than primary series alone, study shows

by York UniversityPrimary series and booster dose model fit results. (A) Example individual model fits for the primary series (blue) and booster dose (orange) Anti-S trajectory data. Dashed lines for

Updated on: May 14,2024 0

COVID-19 booster immunity lasts much longer than primary series alone, study shows

by York UniversityPrimary series and booster dose model fit results. (A) Example individual model fits for the primary series (blue) and booster dose (orange) Anti-S trajectory data. Dashed lines for

Updated on:May 14,2024 0

FDA approves new treatment for dust mite allergies

(HealthDay)—A new treatment for dust mite allergies has won approval from the U.S. Food and Drug Administration.Odactra is a year-round, once-a-day tablet that's dissolved under the tongue. It&#39

Updated on: April 15,2024 11

FDA approves new treatment for dust mite allergies

(HealthDay)—A new treatment for dust mite allergies has won approval from the U.S. Food and Drug Administration.Odactra is a year-round, once-a-day tablet that's dissolved under the tongue. It&#39

Updated on:April 15,2024 11

Non-surgical treatment significantly reduces knee pain for adults, especially those 50 and older

by The Reis GroupCredit: Pixabay/CC0 Public DomainGenicular nerve radiofrequency ablation is a minimally invasive treatment for knee pain due to osteoarthritis of the knee, and can significantly reduc

Updated on: May 23,2024 6

Non-surgical treatment significantly reduces knee pain for adults, especially those 50 and older

by The Reis GroupCredit: Pixabay/CC0 Public DomainGenicular nerve radiofrequency ablation is a minimally invasive treatment for knee pain due to osteoarthritis of the knee, and can significantly reduc

Updated on:May 23,2024 6