How mutation of the APC gene disrupts lymphocyte migration in colon cancer

by Pasteur InstituteMigrating human T lymphocytes revealing a broad protrusion at the leading edge and long adhesive protrusions at the rear. Image obtained by confocal fluorescence microscopy: f

Updated on: April 08,2024 19

How mutation of the APC gene disrupts lymphocyte migration in colon cancer

by Pasteur InstituteMigrating human T lymphocytes revealing a broad protrusion at the leading edge and long adhesive protrusions at the rear. Image obtained by confocal fluorescence microscopy: f

Updated on:April 08,2024 19

Study finds opioids double risk of venous thromboembolism in rheumatoid arthritis patients

by American College of RheumatologyRisk of outcomes (HR, 95% CI) with opioid initiation compared to NSAID initiation after adjustment for propensity score weights and imbalanced covariables (CVD

Updated on: May 13,2024 5

Study finds opioids double risk of venous thromboembolism in rheumatoid arthritis patients

by American College of RheumatologyRisk of outcomes (HR, 95% CI) with opioid initiation compared to NSAID initiation after adjustment for propensity score weights and imbalanced covariables (CVD

Updated on:May 13,2024 5

Researchers identify new way to inhibit immune cells that drive allergic asthma

by Rockefeller University PressActivation of ILC2s causes inflammation in mouse lungs (left), but this is reduced by treatment with Yoda1 to stimulate Piezo1 channels (right). Credit:(2024)

Updated on: April 06,2024 0

Researchers identify new way to inhibit immune cells that drive allergic asthma

by Rockefeller University PressActivation of ILC2s causes inflammation in mouse lungs (left), but this is reduced by treatment with Yoda1 to stimulate Piezo1 channels (right). Credit:(2024)

Updated on:April 06,2024 0

Successful murine model of dermatomyositis reveals underlying immune system involvement

byTokyo Medical and Dental UniversityAutoimmunity to MDA5, CD4 T cells reactive MDA5, works as 'Seed', and inducible factors like as virus infection and poly (I:C) treatment induce type

Updated on: April 28,2024 0

Successful murine model of dermatomyositis reveals underlying immune system involvement

byTokyo Medical and Dental UniversityAutoimmunity to MDA5, CD4 T cells reactive MDA5, works as 'Seed', and inducible factors like as virus infection and poly (I:C) treatment induce type

Updated on:April 28,2024 0

FDA approves new treatment for dust mite allergies

(HealthDay)—A new treatment for dust mite allergies has won approval from the U.S. Food and Drug Administration.Odactra is a year-round, once-a-day tablet that's dissolved under the tongue. It&#39

Updated on: April 15,2024 11

FDA approves new treatment for dust mite allergies

(HealthDay)—A new treatment for dust mite allergies has won approval from the U.S. Food and Drug Administration.Odactra is a year-round, once-a-day tablet that's dissolved under the tongue. It&#39

Updated on:April 15,2024 11

Scientists pioneer immunotherapy technique for autoimmune diseases

byMayo ClinicMSCs are transduced to express CAR and maintain stem-like features following transduction and stimulation. Credit:Nature Biomedical Engineering(2024). DOI: 10.1038/s4155

Updated on: April 06,2024 0

Scientists pioneer immunotherapy technique for autoimmune diseases

byMayo ClinicMSCs are transduced to express CAR and maintain stem-like features following transduction and stimulation. Credit:Nature Biomedical Engineering(2024). DOI: 10.1038/s4155

Updated on:April 06,2024 0

CAR T-cell immunotherapy rids woman of tough-to-treat lupus

by Amy Norton(HealthDay)—In a first, researchers have used genetically tweaked immune system cells to send a woman's severe lupus into remission.The treatment—called CAR T-cell therapy—is already

Updated on: April 09,2024 17

CAR T-cell immunotherapy rids woman of tough-to-treat lupus

by Amy Norton(HealthDay)—In a first, researchers have used genetically tweaked immune system cells to send a woman's severe lupus into remission.The treatment—called CAR T-cell therapy—is already

Updated on:April 09,2024 17

Curbing blood cancers by teaching immune cells to kill mutant stem cells

by Nancy Fliesler,Children's Hospital BostonROS and TLR3 signaling mediates the "eat-me" and "don't eat me" signals that determine stem cell clonal selection by macro

Updated on: October 24,2024 0

Curbing blood cancers by teaching immune cells to kill mutant stem cells

by Nancy Fliesler,Children's Hospital BostonROS and TLR3 signaling mediates the "eat-me" and "don't eat me" signals that determine stem cell clonal selection by macro

Updated on:October 24,2024 0

Treatment effect of tofacitinib, adalimumab compared in RA

by Elana GotkineFor adults with rheumatoid arthritis (RA), there is a modest reduction in the mean Disease Activity Score in 28 joints using C-reactive protein (DAS28-CRP) at three months for patients

Updated on: June 26,2024 7

Treatment effect of tofacitinib, adalimumab compared in RA

by Elana GotkineFor adults with rheumatoid arthritis (RA), there is a modest reduction in the mean Disease Activity Score in 28 joints using C-reactive protein (DAS28-CRP) at three months for patients

Updated on:June 26,2024 7

Non-surgical treatment significantly reduces knee pain for adults, especially those 50 and older

by The Reis GroupCredit: Pixabay/CC0 Public DomainGenicular nerve radiofrequency ablation is a minimally invasive treatment for knee pain due to osteoarthritis of the knee, and can significantly reduc

Updated on: May 23,2024 6

Non-surgical treatment significantly reduces knee pain for adults, especially those 50 and older

by The Reis GroupCredit: Pixabay/CC0 Public DomainGenicular nerve radiofrequency ablation is a minimally invasive treatment for knee pain due to osteoarthritis of the knee, and can significantly reduc

Updated on:May 23,2024 6

COVID-19 booster immunity lasts much longer than primary series alone, study shows

by York UniversityPrimary series and booster dose model fit results. (A) Example individual model fits for the primary series (blue) and booster dose (orange) Anti-S trajectory data. Dashed lines for

Updated on: May 14,2024 0

COVID-19 booster immunity lasts much longer than primary series alone, study shows

by York UniversityPrimary series and booster dose model fit results. (A) Example individual model fits for the primary series (blue) and booster dose (orange) Anti-S trajectory data. Dashed lines for

Updated on:May 14,2024 0

Repurposing tocilizumab in scleroderma patients may prevent early lung disease

by Jordyn Imhoff,University of MichiganCredit: CC0 Public DomainResearch led by Michigan Medicine's Scleroderma Program and published in Arthritis & Rheumatology found that tocilizumab,

Updated on: April 07,2024 16

Repurposing tocilizumab in scleroderma patients may prevent early lung disease

by Jordyn Imhoff,University of MichiganCredit: CC0 Public DomainResearch led by Michigan Medicine's Scleroderma Program and published in Arthritis & Rheumatology found that tocilizumab,

Updated on:April 07,2024 16