Repurposing tocilizumab in scleroderma patients may prevent early lung disease

by Jordyn Imhoff,University of MichiganCredit: CC0 Public DomainResearch led by Michigan Medicine's Scleroderma Program and published in Arthritis & Rheumatology found that tocilizumab,

Updated on: April 07,2024 16

Repurposing tocilizumab in scleroderma patients may prevent early lung disease

by Jordyn Imhoff,University of MichiganCredit: CC0 Public DomainResearch led by Michigan Medicine's Scleroderma Program and published in Arthritis & Rheumatology found that tocilizumab,

Updated on:April 07,2024 16

Tezepelumab significantly reduced asthma exacerbations: Phase 3 NAVIGATOR trial

by American Thoracic SocietyObstruction of the lumen of a bronchiole by mucoid exudate, goblet cell metaplasia, and epithelial basement membrane thickening in a person with asthma. Credit: Yale R

Updated on: May 08,2024 5

Tezepelumab significantly reduced asthma exacerbations: Phase 3 NAVIGATOR trial

by American Thoracic SocietyObstruction of the lumen of a bronchiole by mucoid exudate, goblet cell metaplasia, and epithelial basement membrane thickening in a person with asthma. Credit: Yale R

Updated on:May 08,2024 5

CAR T-cell immunotherapy rids woman of tough-to-treat lupus

by Amy Norton(HealthDay)—In a first, researchers have used genetically tweaked immune system cells to send a woman's severe lupus into remission.The treatment—called CAR T-cell therapy—is already

Updated on: April 09,2024 17

CAR T-cell immunotherapy rids woman of tough-to-treat lupus

by Amy Norton(HealthDay)—In a first, researchers have used genetically tweaked immune system cells to send a woman's severe lupus into remission.The treatment—called CAR T-cell therapy—is already

Updated on:April 09,2024 17

MAIT cells can be tuned to fight different pathogens via their metabolism, leading to new therapeutic strategies

by La Jolla Institute for ImmunologyCredit: Pixabay/CC0 Public DomainA population of unconventional white blood cells has recently captured the attention of immunologists and clinicians alike. Un

Updated on: April 20,2024 16

MAIT cells can be tuned to fight different pathogens via their metabolism, leading to new therapeutic strategies

by La Jolla Institute for ImmunologyCredit: Pixabay/CC0 Public DomainA population of unconventional white blood cells has recently captured the attention of immunologists and clinicians alike. Un

Updated on:April 20,2024 16

Study offers new insights into how immune cells recognize their enemies

by Gunnar Bartsch,Julius-Maximilians-Universität WürzburgPAg induced Vγ9Vδ2 T cell activation by BTN3A-BTN2A1 composite ligand. Credit:Nature Communications(2023). DOI: 10.1038/s4146

Updated on: January 26,2024 12

Study offers new insights into how immune cells recognize their enemies

by Gunnar Bartsch,Julius-Maximilians-Universität WürzburgPAg induced Vγ9Vδ2 T cell activation by BTN3A-BTN2A1 composite ligand. Credit:Nature Communications(2023). DOI: 10.1038/s4146

Updated on:January 26,2024 12

Preventing cell death as novel therapeutic strategy for rheumatoid arthritis

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainA collaborative study has identified a new molecular mechanism causing rheumatoid arthritis. The researchers found that d

Updated on: March 30,2024 19

Preventing cell death as novel therapeutic strategy for rheumatoid arthritis

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainA collaborative study has identified a new molecular mechanism causing rheumatoid arthritis. The researchers found that d

Updated on:March 30,2024 19

How an emerging drug class dampens harmful immune reactions

by Angelika Jacobs,University of BaselOverview of complement mechanisms and compstatin-based inhibitor development.aSimplified scheme of the complement cascade with major effector fu

Updated on: March 25,2024 13

How an emerging drug class dampens harmful immune reactions

by Angelika Jacobs,University of BaselOverview of complement mechanisms and compstatin-based inhibitor development.aSimplified scheme of the complement cascade with major effector fu

Updated on:March 25,2024 13

Secondary structures in DNA are associated with cancer

by Lila Reynolds,Northwestern UniversityCredit: CC0 Public DomainA new cancer study reports that DNA manifested as knot-like folds and third rungs between DNA's two strands may drive cancer

Updated on: April 15,2024 20

Secondary structures in DNA are associated with cancer

by Lila Reynolds,Northwestern UniversityCredit: CC0 Public DomainA new cancer study reports that DNA manifested as knot-like folds and third rungs between DNA's two strands may drive cancer

Updated on:April 15,2024 20

Screening and treating infections in AIIRD

by European Alliance of Associations for Rheumatology (EULAR)Typical screening for hepatitis B virus (HBV) status include HBsAg, anti-HBcore and anti-HBs. HBsAg-positive patients (HBV carriers) would

Updated on: May 26,2024 7

Screening and treating infections in AIIRD

by European Alliance of Associations for Rheumatology (EULAR)Typical screening for hepatitis B virus (HBV) status include HBsAg, anti-HBcore and anti-HBs. HBsAg-positive patients (HBV carriers) would

Updated on:May 26,2024 7

New study points to another possible correlation between sleep and overall good health

by Nova Southeastern UniversityJaime Tartar, Ph.D., Nova Southeastern University. Credit: Nova Southeastern UniversityAs if you didn't already have enough to worry about to keep you up at nig

Updated on: May 08,2024 4

New study points to another possible correlation between sleep and overall good health

by Nova Southeastern UniversityJaime Tartar, Ph.D., Nova Southeastern University. Credit: Nova Southeastern UniversityAs if you didn't already have enough to worry about to keep you up at nig

Updated on:May 08,2024 4

Scientists create device to deliver immunotherapy without side effects

by Houston MethodistSmaller than a grain of rice, this tiny nanodevice, invented by a Houston Methodist scientist, delivers immunotherapy straight into a tumor, eliminating both side effects and

Updated on: April 22,2024 12

Scientists create device to deliver immunotherapy without side effects

by Houston MethodistSmaller than a grain of rice, this tiny nanodevice, invented by a Houston Methodist scientist, delivers immunotherapy straight into a tumor, eliminating both side effects and

Updated on:April 22,2024 12

Initial SARS-CoV-2 vaccinations prime immune cells to respond to subsequent variants, study finds

by Perelman School of Medicine at the University of PennsylvaniaGraphical abstract. Credit:Immunity(2024). DOI: 10.1016/j.immuni.2024.02.017A new study from the Perelman School of Med

Updated on: March 19,2024 13

Initial SARS-CoV-2 vaccinations prime immune cells to respond to subsequent variants, study finds

by Perelman School of Medicine at the University of PennsylvaniaGraphical abstract. Credit:Immunity(2024). DOI: 10.1016/j.immuni.2024.02.017A new study from the Perelman School of Med

Updated on:March 19,2024 13