Secondary structures in DNA are associated with cancer

by Lila Reynolds,Northwestern UniversityCredit: CC0 Public DomainA new cancer study reports that DNA manifested as knot-like folds and third rungs between DNA's two strands may drive cancer

Updated on: April 15,2024 20

Secondary structures in DNA are associated with cancer

by Lila Reynolds,Northwestern UniversityCredit: CC0 Public DomainA new cancer study reports that DNA manifested as knot-like folds and third rungs between DNA's two strands may drive cancer

Updated on:April 15,2024 20

CABYR-a/b and CABYR-c hold promise as targets for specific immunotherapy

by Impact Journals LLC(A) Immunohistochemistry (IHC) staining of testis (positive control). (B) IHC staining of colonic adenocarcinoma. (C) IHC stating of Normal colonic mucosa (negative control). Pur

Updated on: April 08,2024 18

CABYR-a/b and CABYR-c hold promise as targets for specific immunotherapy

by Impact Journals LLC(A) Immunohistochemistry (IHC) staining of testis (positive control). (B) IHC staining of colonic adenocarcinoma. (C) IHC stating of Normal colonic mucosa (negative control). Pur

Updated on:April 08,2024 18

Study offers new insights into how immune cells recognize their enemies

by Gunnar Bartsch,Julius-Maximilians-Universität WürzburgPAg induced Vγ9Vδ2 T cell activation by BTN3A-BTN2A1 composite ligand. Credit:Nature Communications(2023). DOI: 10.1038/s4146

Updated on: January 26,2024 12

Study offers new insights into how immune cells recognize their enemies

by Gunnar Bartsch,Julius-Maximilians-Universität WürzburgPAg induced Vγ9Vδ2 T cell activation by BTN3A-BTN2A1 composite ligand. Credit:Nature Communications(2023). DOI: 10.1038/s4146

Updated on:January 26,2024 12

CAR T-cell immunotherapy rids woman of tough-to-treat lupus

by Amy Norton(HealthDay)—In a first, researchers have used genetically tweaked immune system cells to send a woman's severe lupus into remission.The treatment—called CAR T-cell therapy—is already

Updated on: April 09,2024 17

CAR T-cell immunotherapy rids woman of tough-to-treat lupus

by Amy Norton(HealthDay)—In a first, researchers have used genetically tweaked immune system cells to send a woman's severe lupus into remission.The treatment—called CAR T-cell therapy—is already

Updated on:April 09,2024 17

Knee problems tend to flare up as you age—an orthopedic specialist explains available treatment options

by Angie Brown,The ConversationCredit: CC0 Public DomainKnee injuries are common in athletes, accounting for41% of all athletic injuries. But knee injuries aren't limited to competitiv

Updated on: November 21,2024 0

Knee problems tend to flare up as you age—an orthopedic specialist explains available treatment options

by Angie Brown,The ConversationCredit: CC0 Public DomainKnee injuries are common in athletes, accounting for41% of all athletic injuries. But knee injuries aren't limited to competitiv

Updated on:November 21,2024 0

CAR T cell therapies may lead to reactivation of childhood viral infections

by Justin Jackson , Medical XpressPetabase-scale analysis of viral nucleic acids reveals that HHV-6 is reactivated in human T cells. a, Schematic of life cycles of endogenous human viruses. Viruses ca

Updated on: April 09,2024 10

CAR T cell therapies may lead to reactivation of childhood viral infections

by Justin Jackson , Medical XpressPetabase-scale analysis of viral nucleic acids reveals that HHV-6 is reactivated in human T cells. a, Schematic of life cycles of endogenous human viruses. Viruses ca

Updated on:April 09,2024 10

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

Updated on: April 20,2024 20

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

Updated on:April 20,2024 20

RNA proofreading mistakes drive group of autoimmune diseases

by The Scripps Research InstituteScripps Research Professor Patrick Griffin, PhD, of Jupiter, Florida, co-chairman of the Department of Molecular Medicine, used hydrogen-deuterium exchange mass s

Updated on: April 22,2024 14

RNA proofreading mistakes drive group of autoimmune diseases

by The Scripps Research InstituteScripps Research Professor Patrick Griffin, PhD, of Jupiter, Florida, co-chairman of the Department of Molecular Medicine, used hydrogen-deuterium exchange mass s

Updated on:April 22,2024 14

Hope for treating autoimmune diseases: Researchers explore diagnostic role of the systemic inflammation index

by Flinders UniversityCredit: Unsplash/CC0 Public DomainA routine blood test that measures a patient's inflammation levels could improve the early diagnosis and management of a wide range of

Updated on: April 06,2024 0

Hope for treating autoimmune diseases: Researchers explore diagnostic role of the systemic inflammation index

by Flinders UniversityCredit: Unsplash/CC0 Public DomainA routine blood test that measures a patient's inflammation levels could improve the early diagnosis and management of a wide range of

Updated on:April 06,2024 0

Pain in the back: Preventing and treating spinal arthritis

by Dan Lea,Mayo ClinicCredit: Mayo ClinicMany types of arthritis can affect your musculoskeletal system. Joints are physical points of connection between two bones, and cartilage is the tissue t

Updated on: May 23,2024 5

Pain in the back: Preventing and treating spinal arthritis

by Dan Lea,Mayo ClinicCredit: Mayo ClinicMany types of arthritis can affect your musculoskeletal system. Joints are physical points of connection between two bones, and cartilage is the tissue t

Updated on:May 23,2024 5

Rejuvenation of aging cells helps to cure osteoarthritis through gene therapy

by Chinese Academy of SciencesCBX4 maintains nucleolar homeostasis, alleviates senescence and osteoarthritis. Credit: IOZAging is a risk factor for the development of osteoarthritis (OA), a chron

Updated on: May 13,2024 3

Rejuvenation of aging cells helps to cure osteoarthritis through gene therapy

by Chinese Academy of SciencesCBX4 maintains nucleolar homeostasis, alleviates senescence and osteoarthritis. Credit: IOZAging is a risk factor for the development of osteoarthritis (OA), a chron

Updated on:May 13,2024 3

Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells

byScience China PressDuring viral infection, total m6A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T c

Updated on: January 26,2024 19

Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells

byScience China PressDuring viral infection, total m6A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T c

Updated on:January 26,2024 19