Curbing blood cancers by teaching immune cells to kill mutant stem cells

by Nancy Fliesler,Children's Hospital BostonROS and TLR3 signaling mediates the "eat-me" and "don't eat me" signals that determine stem cell clonal selection by macro

Updated on: October 24,2024 0

Curbing blood cancers by teaching immune cells to kill mutant stem cells

by Nancy Fliesler,Children's Hospital BostonROS and TLR3 signaling mediates the "eat-me" and "don't eat me" signals that determine stem cell clonal selection by macro

Updated on:October 24,2024 0

Rehab or steroid shots: What's best for arthritic knees?

by Dennis Thompson(HealthDay)—Physical therapy for knee arthritis tends to cost patients more out-of-pocket and involves a lot more hassle than a quick steroid shot to soothe an aching joint.But in th

Updated on: May 23,2024 3

Rehab or steroid shots: What's best for arthritic knees?

by Dennis Thompson(HealthDay)—Physical therapy for knee arthritis tends to cost patients more out-of-pocket and involves a lot more hassle than a quick steroid shot to soothe an aching joint.But in th

Updated on:May 23,2024 3

Treatment effect of tofacitinib, adalimumab compared in RA

by Elana GotkineFor adults with rheumatoid arthritis (RA), there is a modest reduction in the mean Disease Activity Score in 28 joints using C-reactive protein (DAS28-CRP) at three months for patients

Updated on: June 26,2024 7

Treatment effect of tofacitinib, adalimumab compared in RA

by Elana GotkineFor adults with rheumatoid arthritis (RA), there is a modest reduction in the mean Disease Activity Score in 28 joints using C-reactive protein (DAS28-CRP) at three months for patients

Updated on:June 26,2024 7

How an emerging drug class dampens harmful immune reactions

by Angelika Jacobs,University of BaselOverview of complement mechanisms and compstatin-based inhibitor development.aSimplified scheme of the complement cascade with major effector fu

Updated on: March 25,2024 13

How an emerging drug class dampens harmful immune reactions

by Angelika Jacobs,University of BaselOverview of complement mechanisms and compstatin-based inhibitor development.aSimplified scheme of the complement cascade with major effector fu

Updated on:March 25,2024 13

Diet rich in fish helps fight asthma

by La Trobe UniversityCredit: CC0 Public DomainA clinical trial led by La Trobe University has shown eating fish such as salmon, trout and sardines as part of a healthy diet can reduce asthma sym

Updated on: April 13,2024 18

Diet rich in fish helps fight asthma

by La Trobe UniversityCredit: CC0 Public DomainA clinical trial led by La Trobe University has shown eating fish such as salmon, trout and sardines as part of a healthy diet can reduce asthma sym

Updated on:April 13,2024 18

Initial SARS-CoV-2 vaccinations prime immune cells to respond to subsequent variants, study finds

by Perelman School of Medicine at the University of PennsylvaniaGraphical abstract. Credit:Immunity(2024). DOI: 10.1016/j.immuni.2024.02.017A new study from the Perelman School of Med

Updated on: March 19,2024 13

Initial SARS-CoV-2 vaccinations prime immune cells to respond to subsequent variants, study finds

by Perelman School of Medicine at the University of PennsylvaniaGraphical abstract. Credit:Immunity(2024). DOI: 10.1016/j.immuni.2024.02.017A new study from the Perelman School of Med

Updated on:March 19,2024 13

We are getting older and heavier, and osteoarthritis is increasing

by Lund UniversityCredit: CC0 Public DomainThe number of patients with osteoarthritis has increased dramatically since the 1950s. Along with diabetes, the illness is now one of the fastest-growin

Updated on: June 01,2024 4

We are getting older and heavier, and osteoarthritis is increasing

by Lund UniversityCredit: CC0 Public DomainThe number of patients with osteoarthritis has increased dramatically since the 1950s. Along with diabetes, the illness is now one of the fastest-growin

Updated on:June 01,2024 4

Preventing cell death as novel therapeutic strategy for rheumatoid arthritis

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainA collaborative study has identified a new molecular mechanism causing rheumatoid arthritis. The researchers found that d

Updated on: March 30,2024 19

Preventing cell death as novel therapeutic strategy for rheumatoid arthritis

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainA collaborative study has identified a new molecular mechanism causing rheumatoid arthritis. The researchers found that d

Updated on:March 30,2024 19

Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells

byScience China PressDuring viral infection, total m6A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T c

Updated on: January 26,2024 19

Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells

byScience China PressDuring viral infection, total m6A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T c

Updated on:January 26,2024 19

ACAAI updates guidance for allergic reactions to COVID-19 vaccines

(HealthDay)—The American College of Allergy, Asthma and Immunology (ACAAI) has updated its guidelines regarding the risk for allergic reactions with COVID-19 vaccines.According to the recommendations,

Updated on: April 02,2024 15

ACAAI updates guidance for allergic reactions to COVID-19 vaccines

(HealthDay)—The American College of Allergy, Asthma and Immunology (ACAAI) has updated its guidelines regarding the risk for allergic reactions with COVID-19 vaccines.According to the recommendations,

Updated on:April 02,2024 15

Time change for biological aging clocks: How immune cells shape our body's true age

by Dartmouth HealthThe association between immune cell composition and EAA for Horvath, Hannum, Pheno, and Zhang, DunedinPACE, and EpiTOC2 TNSC clocks across three age groups (0, 0–18, 18–99). Se

Updated on: March 07,2024 14

Time change for biological aging clocks: How immune cells shape our body's true age

by Dartmouth HealthThe association between immune cell composition and EAA for Horvath, Hannum, Pheno, and Zhang, DunedinPACE, and EpiTOC2 TNSC clocks across three age groups (0, 0–18, 18–99). Se

Updated on:March 07,2024 14

Screening and treating infections in AIIRD

by European Alliance of Associations for Rheumatology (EULAR)Typical screening for hepatitis B virus (HBV) status include HBsAg, anti-HBcore and anti-HBs. HBsAg-positive patients (HBV carriers) would

Updated on: May 26,2024 7

Screening and treating infections in AIIRD

by European Alliance of Associations for Rheumatology (EULAR)Typical screening for hepatitis B virus (HBV) status include HBsAg, anti-HBcore and anti-HBs. HBsAg-positive patients (HBV carriers) would

Updated on:May 26,2024 7