Researchers redesign future mRNA therapeutics to prevent potentially harmful immune responses

byUniversity of CambridgeBiochemist Professor Anne Willis and immunologist Dr James Thaventhiran at the MRC Toxicology Unit at the University of Cambridge led this work. Credit: Mike Thornton, S

Updated on: January 26,2024

Researchers redesign future mRNA therapeutics to prevent potentially harmful immune responses

byUniversity of CambridgeBiochemist Professor Anne Willis and immunologist Dr James Thaventhiran at the MRC Toxicology Unit at the University of Cambridge led this work. Credit: Mike Thornton, S

Updated on:January 26,2024

Successful murine model of dermatomyositis reveals underlying immune system involvement

byTokyo Medical and Dental UniversityAutoimmunity to MDA5, CD4 T cells reactive MDA5, works as 'Seed', and inducible factors like as virus infection and poly (I:C) treatment induce type

Updated on: April 28,2024

Successful murine model of dermatomyositis reveals underlying immune system involvement

byTokyo Medical and Dental UniversityAutoimmunity to MDA5, CD4 T cells reactive MDA5, works as 'Seed', and inducible factors like as virus infection and poly (I:C) treatment induce type

Updated on:April 28,2024

An experimental vaccine against rheumatoid arthritis

by University of ToledoCredit: CC0 Public DomainResearchers at The University of Toledo have developed an experimental vaccine that shows significant promise in preventing rheumatoid arthritis, a

Updated on: June 28,2024

An experimental vaccine against rheumatoid arthritis

by University of ToledoCredit: CC0 Public DomainResearchers at The University of Toledo have developed an experimental vaccine that shows significant promise in preventing rheumatoid arthritis, a

Updated on:June 28,2024

New study reveals how epithelial cells in the body naturally eliminate 'precancerous' ones

by Waseda UniversityWaseda University researchers identify the underlying mechanism behind the extrusion of precancerous cells by epithelial cells, a mechanism that prevents the formation of canc

Updated on: May 07,2024

New study reveals how epithelial cells in the body naturally eliminate 'precancerous' ones

by Waseda UniversityWaseda University researchers identify the underlying mechanism behind the extrusion of precancerous cells by epithelial cells, a mechanism that prevents the formation of canc

Updated on:May 07,2024

How an immune response is driven by one letter difference in DNA

byRadboud UniversityA biphasic circuit regulates IL-1β and IL-37 expression to coordinate pro- and anti-inflammatory processes from within a single TAD. The two functionally opposed states of th

Updated on: January 26,2024

How an immune response is driven by one letter difference in DNA

byRadboud UniversityA biphasic circuit regulates IL-1β and IL-37 expression to coordinate pro- and anti-inflammatory processes from within a single TAD. The two functionally opposed states of th

Updated on:January 26,2024

First-degree relatives have high perceived risk for rheumatoid arthritis

by Elana GotkineFirst-degree relatives (FDRs) of patients with rheumatoid arthritis (RA) have a high perceived risk for developing RA, according to a study published online Dec. 5 inRMD Open.Sar

Updated on: June 26,2024

First-degree relatives have high perceived risk for rheumatoid arthritis

by Elana GotkineFirst-degree relatives (FDRs) of patients with rheumatoid arthritis (RA) have a high perceived risk for developing RA, according to a study published online Dec. 5 inRMD Open.Sar

Updated on:June 26,2024

Primary care provider training program improves rheumatoid arthritis care in Navajo Nation

by American College of RheumatologyMean (SD) pre-training, mean (SD) post-training, and marginal (95% CI) change in performance on RA knowledge test [N=9]. Credit: The Rheumatology Access Expansi

Updated on: May 13,2024

Primary care provider training program improves rheumatoid arthritis care in Navajo Nation

by American College of RheumatologyMean (SD) pre-training, mean (SD) post-training, and marginal (95% CI) change in performance on RA knowledge test [N=9]. Credit: The Rheumatology Access Expansi

Updated on:May 13,2024

Updated: AAV treatment recommendations

by European Alliance of Associations for Rheumatology (EULAR)The 2022 EULAR algorithm for treatment of granulomatosis with polyangiitis (GPA) or microscopic polyangiitis (MPA). Dashed lines indicate s

Updated on: June 15,2024

Updated: AAV treatment recommendations

by European Alliance of Associations for Rheumatology (EULAR)The 2022 EULAR algorithm for treatment of granulomatosis with polyangiitis (GPA) or microscopic polyangiitis (MPA). Dashed lines indicate s

Updated on:June 15,2024

Screening and treating infections in AIIRD

by European Alliance of Associations for Rheumatology (EULAR)Typical screening for hepatitis B virus (HBV) status include HBsAg, anti-HBcore and anti-HBs. HBsAg-positive patients (HBV carriers) would

Updated on: May 26,2024

Screening and treating infections in AIIRD

by European Alliance of Associations for Rheumatology (EULAR)Typical screening for hepatitis B virus (HBV) status include HBsAg, anti-HBcore and anti-HBs. HBsAg-positive patients (HBV carriers) would

Updated on:May 26,2024

Filling data gaps: Gender equity in academic rheumatology

by European Alliance of Associations for Rheumatology, EULARTypical self-reported working hours in a week by role and gender, EULAR and EMEUNET members, 323 responses. The box and whisker chart shows

Updated on: June 01,2024

Filling data gaps: Gender equity in academic rheumatology

by European Alliance of Associations for Rheumatology, EULARTypical self-reported working hours in a week by role and gender, EULAR and EMEUNET members, 323 responses. The box and whisker chart shows

Updated on:June 01,2024

Mayo Clinic Q and A: Springtime allergies

by Cynthia WeissCredit: CC0 Public DomainDEAR MAYO CLINIC: I love the changing seasons and am looking forward to the warmer days of spring. Unfortunately, I am often miserable because of seasonal alle

Updated on: March 04,2024

Mayo Clinic Q and A: Springtime allergies

by Cynthia WeissCredit: CC0 Public DomainDEAR MAYO CLINIC: I love the changing seasons and am looking forward to the warmer days of spring. Unfortunately, I am often miserable because of seasonal alle

Updated on:March 04,2024

Non-surgical treatment significantly reduces knee pain for adults, especially those 50 and older

by The Reis GroupCredit: Pixabay/CC0 Public DomainGenicular nerve radiofrequency ablation is a minimally invasive treatment for knee pain due to osteoarthritis of the knee, and can significantly reduc

Updated on: May 23,2024

Non-surgical treatment significantly reduces knee pain for adults, especially those 50 and older

by The Reis GroupCredit: Pixabay/CC0 Public DomainGenicular nerve radiofrequency ablation is a minimally invasive treatment for knee pain due to osteoarthritis of the knee, and can significantly reduc

Updated on:May 23,2024