CAR T-cell immunotherapy rids woman of tough-to-treat lupus

by Amy Norton(HealthDay)—In a first, researchers have used genetically tweaked immune system cells to send a woman's severe lupus into remission.The treatment—called CAR T-cell therapy—is already

Updated on: April 09,2024 17

CAR T-cell immunotherapy rids woman of tough-to-treat lupus

by Amy Norton(HealthDay)—In a first, researchers have used genetically tweaked immune system cells to send a woman's severe lupus into remission.The treatment—called CAR T-cell therapy—is already

Updated on:April 09,2024 17

Certain criteria may be better than others in RA assessment

(HealthDay)—For patients with rheumatoid arthritis (RA), the performances of the Clinical Disease Activity Index (CDAI) and Simplified Disease Activity Index (SDAI) appear to be better than that of th

Updated on: March 30,2024 13

Certain criteria may be better than others in RA assessment

(HealthDay)—For patients with rheumatoid arthritis (RA), the performances of the Clinical Disease Activity Index (CDAI) and Simplified Disease Activity Index (SDAI) appear to be better than that of th

Updated on:March 30,2024 13

Researchers uncover new mode of action for HUMIRA in rheumatoid arthritis patients

by Rockefeller University PressIn the presence of adalimumab, TNF on the surface of a monocyte interacts with receptor molecules on the surface of two regulatory T cells, thereby promoting their

Updated on: March 24,2024 19

Researchers uncover new mode of action for HUMIRA in rheumatoid arthritis patients

by Rockefeller University PressIn the presence of adalimumab, TNF on the surface of a monocyte interacts with receptor molecules on the surface of two regulatory T cells, thereby promoting their

Updated on:March 24,2024 19

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on: May 14,2024 3

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on:May 14,2024 3

Researchers unlock predictive biomarkers for common hip disorder

by University of MissouriBoxplots of significantly different median urine biomarker concentrations between the DDH cohort and healthy controls (P < 0.05). Median and the interquartile range ar

Updated on: May 19,2024 3

Researchers unlock predictive biomarkers for common hip disorder

by University of MissouriBoxplots of significantly different median urine biomarker concentrations between the DDH cohort and healthy controls (P < 0.05). Median and the interquartile range ar

Updated on:May 19,2024 3

Finger length a 'pointer' to Osteoarthritis

by Monash University(Medical Xpress)—Our fingers could be more important than we think. New research has revealed that the length of a person's finger could become a 'pointer' to thei

Updated on: March 24,2024 11

Finger length a 'pointer' to Osteoarthritis

by Monash University(Medical Xpress)—Our fingers could be more important than we think. New research has revealed that the length of a person's finger could become a 'pointer' to thei

Updated on:March 24,2024 11

Scientists pioneer immunotherapy technique for autoimmune diseases

byMayo ClinicMSCs are transduced to express CAR and maintain stem-like features following transduction and stimulation. Credit:Nature Biomedical Engineering(2024). DOI: 10.1038/s4155

Updated on: April 06,2024 0

Scientists pioneer immunotherapy technique for autoimmune diseases

byMayo ClinicMSCs are transduced to express CAR and maintain stem-like features following transduction and stimulation. Credit:Nature Biomedical Engineering(2024). DOI: 10.1038/s4155

Updated on:April 06,2024 0

Research into autoimmune liver condition suggests unique cell movements may drive disease

by University of BirminghamCD8+T cell internalization into BEC is a consistent event in PBC patients with ongoing disease. a) Representative fluorescence image of liver core biopsy, taken f

Updated on: March 07,2024 19

Research into autoimmune liver condition suggests unique cell movements may drive disease

by University of BirminghamCD8+T cell internalization into BEC is a consistent event in PBC patients with ongoing disease. a) Representative fluorescence image of liver core biopsy, taken f

Updated on:March 07,2024 19

What is rheumatoid arthritis, the condition tennis champion Caroline Wozniacki lives with?

by Fabien B. Vincent and Michelle Leech,The ConversationCredit: AI-generated imageArthritis is a broad term to describe inflammation of the joints which become swollen and painful. There are man

Updated on: June 15,2024 3

What is rheumatoid arthritis, the condition tennis champion Caroline Wozniacki lives with?

by Fabien B. Vincent and Michelle Leech,The ConversationCredit: AI-generated imageArthritis is a broad term to describe inflammation of the joints which become swollen and painful. There are man

Updated on:June 15,2024 3

Got osteoarthritis? Get moving

(HealthDay)—Is arthritis pain getting in the way of your fitness plans? That need not be the case.In fact,physical activitycan be vital to your continued mobility.Osteoarthritis is a

Updated on: April 07,2024 19

Got osteoarthritis? Get moving

(HealthDay)—Is arthritis pain getting in the way of your fitness plans? That need not be the case.In fact,physical activitycan be vital to your continued mobility.Osteoarthritis is a

Updated on:April 07,2024 19

Secondary structures in DNA are associated with cancer

by Lila Reynolds,Northwestern UniversityCredit: CC0 Public DomainA new cancer study reports that DNA manifested as knot-like folds and third rungs between DNA's two strands may drive cancer

Updated on: April 15,2024 20

Secondary structures in DNA are associated with cancer

by Lila Reynolds,Northwestern UniversityCredit: CC0 Public DomainA new cancer study reports that DNA manifested as knot-like folds and third rungs between DNA's two strands may drive cancer

Updated on:April 15,2024 20

A mathematical model that predicts how severe hay fever season will be

by Bob Yirka , Medical XpressCredit: Pixabay/CC0 Public DomainAn international team of researchers has developed a mathematical model for predicting how bad an upcoming hay fever season will be. In th

Updated on: May 07,2024 10

A mathematical model that predicts how severe hay fever season will be

by Bob Yirka , Medical XpressCredit: Pixabay/CC0 Public DomainAn international team of researchers has developed a mathematical model for predicting how bad an upcoming hay fever season will be. In th

Updated on:May 07,2024 10