Time change for biological aging clocks: How immune cells shape our body's true age

by Dartmouth HealthThe association between immune cell composition and EAA for Horvath, Hannum, Pheno, and Zhang, DunedinPACE, and EpiTOC2 TNSC clocks across three age groups (0, 0–18, 18–99). Se

Updated on: March 07,2024

Time change for biological aging clocks: How immune cells shape our body's true age

by Dartmouth HealthThe association between immune cell composition and EAA for Horvath, Hannum, Pheno, and Zhang, DunedinPACE, and EpiTOC2 TNSC clocks across three age groups (0, 0–18, 18–99). Se

Updated on:March 07,2024

Preventing cell death as novel therapeutic strategy for rheumatoid arthritis

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainA collaborative study has identified a new molecular mechanism causing rheumatoid arthritis. The researchers found that d

Updated on: March 30,2024

Preventing cell death as novel therapeutic strategy for rheumatoid arthritis

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainA collaborative study has identified a new molecular mechanism causing rheumatoid arthritis. The researchers found that d

Updated on:March 30,2024

What do you know about rheumatic diseases?

by Laurel Kelly, Mayo Clinic News NetworkCredit: CC0 Public DomainSeptember is Rheumatic Disease Awareness Month, which makes this a good time to learn about four common rheumatic diseases: Ankylosing

Updated on: June 26,2024

What do you know about rheumatic diseases?

by Laurel Kelly, Mayo Clinic News NetworkCredit: CC0 Public DomainSeptember is Rheumatic Disease Awareness Month, which makes this a good time to learn about four common rheumatic diseases: Ankylosing

Updated on:June 26,2024

Screening of patients with rheumatism improves insight into cardiovascular disease

by University of TwenteSince the fifties, researchers have observed that patients with rheumatoid arthritis have an increased mortality from cardiovascular disease. Patients with this form of rhe

Updated on: May 13,2024

Screening of patients with rheumatism improves insight into cardiovascular disease

by University of TwenteSince the fifties, researchers have observed that patients with rheumatoid arthritis have an increased mortality from cardiovascular disease. Patients with this form of rhe

Updated on:May 13,2024

ATP from sensory neuron-interneuron crosstalk is key to spreading inflammation in rheumatoid arthritis

by Hokkaido UniversityThe inflammation signal (IL-6 amplifier) in the affected joint (L) causes the secretion of ATP that transmits a signal through the spinal cord (DRG, L5), which in turn trigg

Updated on: June 06,2024

ATP from sensory neuron-interneuron crosstalk is key to spreading inflammation in rheumatoid arthritis

by Hokkaido UniversityThe inflammation signal (IL-6 amplifier) in the affected joint (L) causes the secretion of ATP that transmits a signal through the spinal cord (DRG, L5), which in turn trigg

Updated on:June 06,2024

An extra X chromosome-linked gene may explain decreased viral infection severity in females

by University of California, Los AngelesCredit: CC0 Public DomainIt has long been known that viral infections can be more severe in males than females, but the question as to why has remained a m

Updated on: April 24,2024

An extra X chromosome-linked gene may explain decreased viral infection severity in females

by University of California, Los AngelesCredit: CC0 Public DomainIt has long been known that viral infections can be more severe in males than females, but the question as to why has remained a m

Updated on:April 24,2024

Pain in the back: Preventing and treating spinal arthritis

by Dan Lea,Mayo ClinicCredit: Mayo ClinicMany types of arthritis can affect your musculoskeletal system. Joints are physical points of connection between two bones, and cartilage is the tissue t

Updated on: May 23,2024

Pain in the back: Preventing and treating spinal arthritis

by Dan Lea,Mayo ClinicCredit: Mayo ClinicMany types of arthritis can affect your musculoskeletal system. Joints are physical points of connection between two bones, and cartilage is the tissue t

Updated on:May 23,2024

How an emerging drug class dampens harmful immune reactions

by Angelika Jacobs,University of BaselOverview of complement mechanisms and compstatin-based inhibitor development.aSimplified scheme of the complement cascade with major effector fu

Updated on: March 25,2024

How an emerging drug class dampens harmful immune reactions

by Angelika Jacobs,University of BaselOverview of complement mechanisms and compstatin-based inhibitor development.aSimplified scheme of the complement cascade with major effector fu

Updated on:March 25,2024

Immunity after COVID-19 illness may last at least 1 year

by Ernie MundellLong-term data from northern Italy—an area hit hard during the early days of the pandemic—suggests that reinfection after recovery from COVID-19 infection is very rare, and immunity in

Updated on: April 10,2024

Immunity after COVID-19 illness may last at least 1 year

by Ernie MundellLong-term data from northern Italy—an area hit hard during the early days of the pandemic—suggests that reinfection after recovery from COVID-19 infection is very rare, and immunity in

Updated on:April 10,2024

Are low blood urate levels linked to a higher risk of premature death?

by WileyCredit: Unsplash/CC0 Public DomainNew research published inArthritis & Rheumatologysuggests that adults with low blood levels of urate, a breakdown product of metabolism,

Updated on: May 23,2024

Are low blood urate levels linked to a higher risk of premature death?

by WileyCredit: Unsplash/CC0 Public DomainNew research published inArthritis & Rheumatologysuggests that adults with low blood levels of urate, a breakdown product of metabolism,

Updated on:May 23,2024

Researchers describe how birch pollen affects immune cells

by Jan Grabowski, Zentrum für Experimentelle und Klinische InfektionsforschungAPE exposure induces transcriptional changes in moDC. (A) IL-12p70 content in supernatants of moDC stimulated with 100 ng/

Updated on: March 05,2024

Researchers describe how birch pollen affects immune cells

by Jan Grabowski, Zentrum für Experimentelle und Klinische InfektionsforschungAPE exposure induces transcriptional changes in moDC. (A) IL-12p70 content in supernatants of moDC stimulated with 100 ng/

Updated on:March 05,2024

Once considered rare, an itchy dermatologic skin disorder is more common than thought

by Johns Hopkins UniversityCredit: CC0 Public DomainJohns Hopkins researchers report that prurigo nodularis (PN), a skin disease characterized by severely itchy, firm bumps on the skin, may be as

Updated on: April 24,2024

Once considered rare, an itchy dermatologic skin disorder is more common than thought

by Johns Hopkins UniversityCredit: CC0 Public DomainJohns Hopkins researchers report that prurigo nodularis (PN), a skin disease characterized by severely itchy, firm bumps on the skin, may be as

Updated on:April 24,2024