Repurposing tocilizumab in scleroderma patients may prevent early lung disease

by Jordyn Imhoff,University of MichiganCredit: CC0 Public DomainResearch led by Michigan Medicine's Scleroderma Program and published in Arthritis & Rheumatology found that tocilizumab,

Updated on: April 07,2024

Repurposing tocilizumab in scleroderma patients may prevent early lung disease

by Jordyn Imhoff,University of MichiganCredit: CC0 Public DomainResearch led by Michigan Medicine's Scleroderma Program and published in Arthritis & Rheumatology found that tocilizumab,

Updated on:April 07,2024

Time change for biological aging clocks: How immune cells shape our body's true age

by Dartmouth HealthThe association between immune cell composition and EAA for Horvath, Hannum, Pheno, and Zhang, DunedinPACE, and EpiTOC2 TNSC clocks across three age groups (0, 0–18, 18–99). Se

Updated on: March 07,2024

Time change for biological aging clocks: How immune cells shape our body's true age

by Dartmouth HealthThe association between immune cell composition and EAA for Horvath, Hannum, Pheno, and Zhang, DunedinPACE, and EpiTOC2 TNSC clocks across three age groups (0, 0–18, 18–99). Se

Updated on:March 07,2024

Preventing cell death as novel therapeutic strategy for rheumatoid arthritis

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainA collaborative study has identified a new molecular mechanism causing rheumatoid arthritis. The researchers found that d

Updated on: March 30,2024

Preventing cell death as novel therapeutic strategy for rheumatoid arthritis

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainA collaborative study has identified a new molecular mechanism causing rheumatoid arthritis. The researchers found that d

Updated on:March 30,2024

Lockdown impact: Worsening symptoms for people with bone, joint and muscle pain

by University of East AngliaCredit: CC0 Public DomainPeople with bone, joint and muscle pain saw their symptoms worsen during lockdown—according to new research from the University of East Anglia

Updated on: May 26,2024

Lockdown impact: Worsening symptoms for people with bone, joint and muscle pain

by University of East AngliaCredit: CC0 Public DomainPeople with bone, joint and muscle pain saw their symptoms worsen during lockdown—according to new research from the University of East Anglia

Updated on:May 26,2024

Pain in the back: Preventing and treating spinal arthritis

by Dan Lea,Mayo ClinicCredit: Mayo ClinicMany types of arthritis can affect your musculoskeletal system. Joints are physical points of connection between two bones, and cartilage is the tissue t

Updated on: May 23,2024

Pain in the back: Preventing and treating spinal arthritis

by Dan Lea,Mayo ClinicCredit: Mayo ClinicMany types of arthritis can affect your musculoskeletal system. Joints are physical points of connection between two bones, and cartilage is the tissue t

Updated on:May 23,2024

Updated: AAV treatment recommendations

by European Alliance of Associations for Rheumatology (EULAR)The 2022 EULAR algorithm for treatment of granulomatosis with polyangiitis (GPA) or microscopic polyangiitis (MPA). Dashed lines indicate s

Updated on: June 15,2024

Updated: AAV treatment recommendations

by European Alliance of Associations for Rheumatology (EULAR)The 2022 EULAR algorithm for treatment of granulomatosis with polyangiitis (GPA) or microscopic polyangiitis (MPA). Dashed lines indicate s

Updated on:June 15,2024

New analysis finds belimumab improves cutaneous lupus erythematosus in patients with or without SLE

by American College of RheumatologyForest plot of clinical response in CLE with or without SLE in belimumab users vs. non-users at week 52. Credit: Significant Improvement in Cutaneous Lupus Eryt

Updated on: May 29,2024

New analysis finds belimumab improves cutaneous lupus erythematosus in patients with or without SLE

by American College of RheumatologyForest plot of clinical response in CLE with or without SLE in belimumab users vs. non-users at week 52. Credit: Significant Improvement in Cutaneous Lupus Eryt

Updated on:May 29,2024

Once considered rare, an itchy dermatologic skin disorder is more common than thought

by Johns Hopkins UniversityCredit: CC0 Public DomainJohns Hopkins researchers report that prurigo nodularis (PN), a skin disease characterized by severely itchy, firm bumps on the skin, may be as

Updated on: April 24,2024

Once considered rare, an itchy dermatologic skin disorder is more common than thought

by Johns Hopkins UniversityCredit: CC0 Public DomainJohns Hopkins researchers report that prurigo nodularis (PN), a skin disease characterized by severely itchy, firm bumps on the skin, may be as

Updated on:April 24,2024

An extra X chromosome-linked gene may explain decreased viral infection severity in females

by University of California, Los AngelesCredit: CC0 Public DomainIt has long been known that viral infections can be more severe in males than females, but the question as to why has remained a m

Updated on: April 24,2024

An extra X chromosome-linked gene may explain decreased viral infection severity in females

by University of California, Los AngelesCredit: CC0 Public DomainIt has long been known that viral infections can be more severe in males than females, but the question as to why has remained a m

Updated on:April 24,2024

Are low blood urate levels linked to a higher risk of premature death?

by WileyCredit: Unsplash/CC0 Public DomainNew research published inArthritis & Rheumatologysuggests that adults with low blood levels of urate, a breakdown product of metabolism,

Updated on: May 23,2024

Are low blood urate levels linked to a higher risk of premature death?

by WileyCredit: Unsplash/CC0 Public DomainNew research published inArthritis & Rheumatologysuggests that adults with low blood levels of urate, a breakdown product of metabolism,

Updated on:May 23,2024

STIM-mediated calcium influx regulates maintenance and selection of germinal center B cells: Study

by Osaka UniversityCredit:Journal of Experimental Medicine(2023). DOI: 10.1084/jem.20222178Germinal centers (GCs) are specialized microenvironments where antigen (Ag)-specific B cells

Updated on: April 22,2024

STIM-mediated calcium influx regulates maintenance and selection of germinal center B cells: Study

by Osaka UniversityCredit:Journal of Experimental Medicine(2023). DOI: 10.1084/jem.20222178Germinal centers (GCs) are specialized microenvironments where antigen (Ag)-specific B cells

Updated on:April 22,2024

How an emerging drug class dampens harmful immune reactions

by Angelika Jacobs,University of BaselOverview of complement mechanisms and compstatin-based inhibitor development.aSimplified scheme of the complement cascade with major effector fu

Updated on: March 25,2024

How an emerging drug class dampens harmful immune reactions

by Angelika Jacobs,University of BaselOverview of complement mechanisms and compstatin-based inhibitor development.aSimplified scheme of the complement cascade with major effector fu

Updated on:March 25,2024