ATP from sensory neuron-interneuron crosstalk is key to spreading inflammation in rheumatoid arthritis

by Hokkaido UniversityThe inflammation signal (IL-6 amplifier) in the affected joint (L) causes the secretion of ATP that transmits a signal through the spinal cord (DRG, L5), which in turn trigg

Updated on: June 06,2024

ATP from sensory neuron-interneuron crosstalk is key to spreading inflammation in rheumatoid arthritis

by Hokkaido UniversityThe inflammation signal (IL-6 amplifier) in the affected joint (L) causes the secretion of ATP that transmits a signal through the spinal cord (DRG, L5), which in turn trigg

Updated on:June 06,2024

Screening of patients with rheumatism improves insight into cardiovascular disease

by University of TwenteSince the fifties, researchers have observed that patients with rheumatoid arthritis have an increased mortality from cardiovascular disease. Patients with this form of rhe

Updated on: May 13,2024

Screening of patients with rheumatism improves insight into cardiovascular disease

by University of TwenteSince the fifties, researchers have observed that patients with rheumatoid arthritis have an increased mortality from cardiovascular disease. Patients with this form of rhe

Updated on:May 13,2024

Preventing cell death as novel therapeutic strategy for rheumatoid arthritis

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainA collaborative study has identified a new molecular mechanism causing rheumatoid arthritis. The researchers found that d

Updated on: March 30,2024

Preventing cell death as novel therapeutic strategy for rheumatoid arthritis

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainA collaborative study has identified a new molecular mechanism causing rheumatoid arthritis. The researchers found that d

Updated on:March 30,2024

New method is better able to map immune response and paves way for new treatments

byKarolinska InstitutetSpatial transcriptomics–based method to map B cell and T cell receptors.Targeted capture of antigen receptor sequences from spatial transcriptomics gene expression librari

Updated on: January 26,2024

New method is better able to map immune response and paves way for new treatments

byKarolinska InstitutetSpatial transcriptomics–based method to map B cell and T cell receptors.Targeted capture of antigen receptor sequences from spatial transcriptomics gene expression librari

Updated on:January 26,2024

Researchers describe how birch pollen affects immune cells

by Jan Grabowski, Zentrum für Experimentelle und Klinische InfektionsforschungAPE exposure induces transcriptional changes in moDC. (A) IL-12p70 content in supernatants of moDC stimulated with 100 ng/

Updated on: March 05,2024

Researchers describe how birch pollen affects immune cells

by Jan Grabowski, Zentrum für Experimentelle und Klinische InfektionsforschungAPE exposure induces transcriptional changes in moDC. (A) IL-12p70 content in supernatants of moDC stimulated with 100 ng/

Updated on:March 05,2024

New study reveals how epithelial cells in the body naturally eliminate 'precancerous' ones

by Waseda UniversityWaseda University researchers identify the underlying mechanism behind the extrusion of precancerous cells by epithelial cells, a mechanism that prevents the formation of canc

Updated on: May 07,2024

New study reveals how epithelial cells in the body naturally eliminate 'precancerous' ones

by Waseda UniversityWaseda University researchers identify the underlying mechanism behind the extrusion of precancerous cells by epithelial cells, a mechanism that prevents the formation of canc

Updated on:May 07,2024

An extra X chromosome-linked gene may explain decreased viral infection severity in females

by University of California, Los AngelesCredit: CC0 Public DomainIt has long been known that viral infections can be more severe in males than females, but the question as to why has remained a m

Updated on: April 24,2024

An extra X chromosome-linked gene may explain decreased viral infection severity in females

by University of California, Los AngelesCredit: CC0 Public DomainIt has long been known that viral infections can be more severe in males than females, but the question as to why has remained a m

Updated on:April 24,2024

Smokers who consume too much sodium at greater risk of developing rheumatoid arthritis

by Oxford University PressCredit: Vera Kratochvil/public domainA new study published online in the journalRheumatologytoday indicates that the interaction between high sodium intake a

Updated on: May 13,2024

Smokers who consume too much sodium at greater risk of developing rheumatoid arthritis

by Oxford University PressCredit: Vera Kratochvil/public domainA new study published online in the journalRheumatologytoday indicates that the interaction between high sodium intake a

Updated on:May 13,2024

Findings give hope to plant extract as possible lupus treatment

by University of HoustonNew findings by UH biomedical engineer Chandra Mohan and his team raise hope for a new class of drugs to treat lupus that may not include the long list of adverse risks an

Updated on: June 15,2024

Findings give hope to plant extract as possible lupus treatment

by University of HoustonNew findings by UH biomedical engineer Chandra Mohan and his team raise hope for a new class of drugs to treat lupus that may not include the long list of adverse risks an

Updated on:June 15,2024

How an emerging drug class dampens harmful immune reactions

by Angelika Jacobs,University of BaselOverview of complement mechanisms and compstatin-based inhibitor development.aSimplified scheme of the complement cascade with major effector fu

Updated on: March 25,2024

How an emerging drug class dampens harmful immune reactions

by Angelika Jacobs,University of BaselOverview of complement mechanisms and compstatin-based inhibitor development.aSimplified scheme of the complement cascade with major effector fu

Updated on:March 25,2024

Risk of severe breakthrough COVID-19 infection is higher for people with HIV with moderately low CD4 cell counts

by Johns Hopkins University Bloomberg School of Public HealthGraphs show incidence of severe COVID-19 breakthrough illness by HIV status (A) (log-rank test P = .40), by CD4 cell count and HIV sta

Updated on: April 09,2024

Risk of severe breakthrough COVID-19 infection is higher for people with HIV with moderately low CD4 cell counts

by Johns Hopkins University Bloomberg School of Public HealthGraphs show incidence of severe COVID-19 breakthrough illness by HIV status (A) (log-rank test P = .40), by CD4 cell count and HIV sta

Updated on:April 09,2024

Knee arthritis: Steroid shots may not help long-term, ozone injections promising

Two studies test out old and new treatments for the debilitating ailment.(HealthDay)—Millions of aging Americans are plagued by arthritic knees, and two new studies offer insight into what might—or mi

Updated on: April 08,2024

Knee arthritis: Steroid shots may not help long-term, ozone injections promising

Two studies test out old and new treatments for the debilitating ailment.(HealthDay)—Millions of aging Americans are plagued by arthritic knees, and two new studies offer insight into what might—or mi

Updated on:April 08,2024