Eyes serve as immunological barrier in fight against brain pathogens, finds study

by Yale University10x VISIUM Spatial sequencing of the mouse globe and optic nerve. Mouse eyes were processed using traditional FFPE-based histology preparation. Samples were processed using the

Updated on: March 07,2024 15

Eyes serve as immunological barrier in fight against brain pathogens, finds study

by Yale University10x VISIUM Spatial sequencing of the mouse globe and optic nerve. Mouse eyes were processed using traditional FFPE-based histology preparation. Samples were processed using the

Updated on:March 07,2024 15

Researchers reveal molecular mechanism of cytokine storm induced by coronavirus

by Zhang Nannan,Chinese Academy of SciencesSARS-CoV-2 stabilizes host mRNAs to induce cytokine storm. Credit: Xue Yuanchao's groupIn the past four years, the pathogen responsible for Coronav

Updated on: January 26,2024 21

Researchers reveal molecular mechanism of cytokine storm induced by coronavirus

by Zhang Nannan,Chinese Academy of SciencesSARS-CoV-2 stabilizes host mRNAs to induce cytokine storm. Credit: Xue Yuanchao's groupIn the past four years, the pathogen responsible for Coronav

Updated on:January 26,2024 21

Study uncovers true burden of asthma in African schools and highlights need for better access to diagnosis and care

byQueen Mary, University of LondonCredit: Pixabay/CC0 Public DomainAsthma is the second most common cause of chronic respiratory deaths in the overall population of sub-Saharan Africa. The study

Updated on: October 30,2024 0

Study uncovers true burden of asthma in African schools and highlights need for better access to diagnosis and care

byQueen Mary, University of LondonCredit: Pixabay/CC0 Public DomainAsthma is the second most common cause of chronic respiratory deaths in the overall population of sub-Saharan Africa. The study

Updated on:October 30,2024 0

How much of a boost do 'booster' COVID-19 jabs give?

by King's College LondonCredit: Pixabay/CC0 Public DomainScientists have found the "booster" COVID-19 vaccine program led to a large boost in the antibodies that help protect agains

Updated on: March 13,2024 19

How much of a boost do 'booster' COVID-19 jabs give?

by King's College LondonCredit: Pixabay/CC0 Public DomainScientists have found the "booster" COVID-19 vaccine program led to a large boost in the antibodies that help protect agains

Updated on:March 13,2024 19

An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on: March 30,2024 8

An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on:March 30,2024 8

How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on: March 27,2024 0

How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on:March 27,2024 0

Mortality rate up for Koreans with rheumatoid arthritis

(HealthDay)—Korean patients with rheumatoid arthritis (RA) have increased mortality rates compared with the general population, according to a study published online Jan. 19 in theInternational

Updated on: May 08,2024 6

Mortality rate up for Koreans with rheumatoid arthritis

(HealthDay)—Korean patients with rheumatoid arthritis (RA) have increased mortality rates compared with the general population, according to a study published online Jan. 19 in theInternational

Updated on:May 08,2024 6

Oral deucravacitinib benefits patients with lupus

by WileyCredit: CC0 Public DomainTyrosine kinases are enzymes that play central roles in signaling by cytokines involved in the pathogenesis of autoimmune diseases, including lupus. A recent phas

Updated on: June 06,2024 5

Oral deucravacitinib benefits patients with lupus

by WileyCredit: CC0 Public DomainTyrosine kinases are enzymes that play central roles in signaling by cytokines involved in the pathogenesis of autoimmune diseases, including lupus. A recent phas

Updated on:June 06,2024 5

Study finds cycling JAK inhibitors to be an effective option for patients with difficult-to-treat rheumatoid arthritis

by American College of RheumatologyCredit: Unsplash/CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that peo

Updated on: May 29,2024 3

Study finds cycling JAK inhibitors to be an effective option for patients with difficult-to-treat rheumatoid arthritis

by American College of RheumatologyCredit: Unsplash/CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that peo

Updated on:May 29,2024 3

Mpox: Characterization of post-infectious immune response

by Pasteur InstituteHuman cells infected with MPXV (in green) among uninfected cells (nuclei in blue). Image taken with a confocal microscope. Credit: Mathieu Hubert and Olivier Schwartz, Institu

Updated on: April 20,2024 11

Mpox: Characterization of post-infectious immune response

by Pasteur InstituteHuman cells infected with MPXV (in green) among uninfected cells (nuclei in blue). Image taken with a confocal microscope. Credit: Mathieu Hubert and Olivier Schwartz, Institu

Updated on:April 20,2024 11

Rheumatoid arthritis patients see big boost in quality of life

by Alan Mozes, Healthday ReporterDutch study found substantial drops in anxiety, depression and disability over 2 decades.(HealthDay)—Rheumatoid arthritis patients can generally look forward to a much

Updated on: March 24,2024 19

Rheumatoid arthritis patients see big boost in quality of life

by Alan Mozes, Healthday ReporterDutch study found substantial drops in anxiety, depression and disability over 2 decades.(HealthDay)—Rheumatoid arthritis patients can generally look forward to a much

Updated on:March 24,2024 19

B cells gone bad could be the culprit in rheumatoid arthritis

by Laurie Fickman,University of HoustonBiomolecular researcher Navin Varadarajan anticipates that his data will serve as a foundation for investigating multiple hypotheses on the roles of B cell

Updated on: April 08,2024 14

B cells gone bad could be the culprit in rheumatoid arthritis

by Laurie Fickman,University of HoustonBiomolecular researcher Navin Varadarajan anticipates that his data will serve as a foundation for investigating multiple hypotheses on the roles of B cell

Updated on:April 08,2024 14