New algorithm may greatly speed up the design of 'humanized' antibodies that work

by Weizmann Institute of Science3D structure of an antibody’s “finger,” the portion that binds to a target. The colored regions are responsible for recognizing the target; the gray regions provid

Updated on: March 07,2024

New algorithm may greatly speed up the design of 'humanized' antibodies that work

by Weizmann Institute of Science3D structure of an antibody’s “finger,” the portion that binds to a target. The colored regions are responsible for recognizing the target; the gray regions provid

Updated on:March 07,2024

Optimizing boosters: How COVID mRNA vaccines reshape immune memory after each dose

by Tokyo University of ScienceChanges in the clonal populations of CD8+T- cells after successive vaccinations, an ability that can be tuned for developing more effective mRNA vaccines. Cred

Updated on: March 19,2024

Optimizing boosters: How COVID mRNA vaccines reshape immune memory after each dose

by Tokyo University of ScienceChanges in the clonal populations of CD8+T- cells after successive vaccinations, an ability that can be tuned for developing more effective mRNA vaccines. Cred

Updated on:March 19,2024

Preventing cell death as novel therapeutic strategy for rheumatoid arthritis

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainA collaborative study has identified a new molecular mechanism causing rheumatoid arthritis. The researchers found that d

Updated on: March 30,2024

Preventing cell death as novel therapeutic strategy for rheumatoid arthritis

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainA collaborative study has identified a new molecular mechanism causing rheumatoid arthritis. The researchers found that d

Updated on:March 30,2024

New approach to arthritis treatment could avoid serious side-effects

by Queen Mary, University of London(Medical Xpress)—A new approach to arthritis treatment, which avoids unforeseen side-effects by delivering drugs exclusively to affected inflamed joints, has be

Updated on: March 26,2024

New approach to arthritis treatment could avoid serious side-effects

by Queen Mary, University of London(Medical Xpress)—A new approach to arthritis treatment, which avoids unforeseen side-effects by delivering drugs exclusively to affected inflamed joints, has be

Updated on:March 26,2024

Consensus statement issued on management of foot, ankle gout

(HealthDay)—The American College of Foot and Ankle Surgeons and the American Association of Nurse Practitioners-Orthopedics Specialty Practice Group have issued a new joint clinical consensus statemen

Updated on: April 20,2024

Consensus statement issued on management of foot, ankle gout

(HealthDay)—The American College of Foot and Ankle Surgeons and the American Association of Nurse Practitioners-Orthopedics Specialty Practice Group have issued a new joint clinical consensus statemen

Updated on:April 20,2024

A novel animal model for analysing human natural killer cell functions in vivo

by Kawasaki CityFigure 1: Humanized mice were generated by transplanting 2.5 x 104 human cord blood-derived CD34+ HSC cells into irradiated NOG-IL-2 mice. After human CD34+ cell transplantation, human

Updated on: March 25,2024

A novel animal model for analysing human natural killer cell functions in vivo

by Kawasaki CityFigure 1: Humanized mice were generated by transplanting 2.5 x 104 human cord blood-derived CD34+ HSC cells into irradiated NOG-IL-2 mice. After human CD34+ cell transplantation, human

Updated on:March 25,2024

Psoriasis patients can get clearer skin with at-home treatment instead of at doctors' offices, study suggests

by Alex Gardner,Perelman School of Medicine at the University of PennsylvaniaCredit: Estzer Miller on PixabayFor decades, people with psoriasis have been treated in clinics with narrowband ultra

Updated on: October 28,2024

Psoriasis patients can get clearer skin with at-home treatment instead of at doctors' offices, study suggests

by Alex Gardner,Perelman School of Medicine at the University of PennsylvaniaCredit: Estzer Miller on PixabayFor decades, people with psoriasis have been treated in clinics with narrowband ultra

Updated on:October 28,2024

Urine of COVID-19 patients could predict who will develop severe disease

by American Physiological SocietyCredit: Unsplash/CC0 Public DomainUrine analysis of COVID-19 patients revealed elevated levels of specific biomarkers of the immune system compared to those who w

Updated on: April 10,2024

Urine of COVID-19 patients could predict who will develop severe disease

by American Physiological SocietyCredit: Unsplash/CC0 Public DomainUrine analysis of COVID-19 patients revealed elevated levels of specific biomarkers of the immune system compared to those who w

Updated on:April 10,2024

New strategy for COVID-19 prophylaxis

by University of BonnPhD student Samira Marx and Prof. Dr. Gunther Hartmann - of the Cluster of Excellence ImmunoSensation2 at the University of Bonn in the lab. Credit: David FußhöllerSARS-CoV-2

Updated on: April 13,2024

New strategy for COVID-19 prophylaxis

by University of BonnPhD student Samira Marx and Prof. Dr. Gunther Hartmann - of the Cluster of Excellence ImmunoSensation2 at the University of Bonn in the lab. Credit: David FußhöllerSARS-CoV-2

Updated on:April 13,2024

Filling data gaps: Gender equity in academic rheumatology

by European Alliance of Associations for Rheumatology, EULARTypical self-reported working hours in a week by role and gender, EULAR and EMEUNET members, 323 responses. The box and whisker chart shows

Updated on: June 01,2024

Filling data gaps: Gender equity in academic rheumatology

by European Alliance of Associations for Rheumatology, EULARTypical self-reported working hours in a week by role and gender, EULAR and EMEUNET members, 323 responses. The box and whisker chart shows

Updated on:June 01,2024

Screening of patients with rheumatism improves insight into cardiovascular disease

by University of TwenteSince the fifties, researchers have observed that patients with rheumatoid arthritis have an increased mortality from cardiovascular disease. Patients with this form of rhe

Updated on: May 13,2024

Screening of patients with rheumatism improves insight into cardiovascular disease

by University of TwenteSince the fifties, researchers have observed that patients with rheumatoid arthritis have an increased mortality from cardiovascular disease. Patients with this form of rhe

Updated on:May 13,2024

Risk of severe breakthrough COVID-19 infection is higher for people with HIV with moderately low CD4 cell counts

by Johns Hopkins University Bloomberg School of Public HealthGraphs show incidence of severe COVID-19 breakthrough illness by HIV status (A) (log-rank test P = .40), by CD4 cell count and HIV sta

Updated on: April 09,2024

Risk of severe breakthrough COVID-19 infection is higher for people with HIV with moderately low CD4 cell counts

by Johns Hopkins University Bloomberg School of Public HealthGraphs show incidence of severe COVID-19 breakthrough illness by HIV status (A) (log-rank test P = .40), by CD4 cell count and HIV sta

Updated on:April 09,2024