Review discusses metabolic reprogramming of T cells

by Cactus CommunicationsT cell immunotherapy can be optimized by understanding the metabolism of T cells. This review article summarizes the intricacies of effector and memory T cell metabolic reprogr

Updated on: March 07,2024

Review discusses metabolic reprogramming of T cells

by Cactus CommunicationsT cell immunotherapy can be optimized by understanding the metabolism of T cells. This review article summarizes the intricacies of effector and memory T cell metabolic reprogr

Updated on:March 07,2024

Developing new classification criteria for improving antiphospholipid syndrome research

by Hospital for Special SurgeryCredit: CC0 Public DomainAn international team of more than 80 collaborators led by Hospital for Special Surgery (HSS) investigators is developing new classificatio

Updated on: March 26,2024

Developing new classification criteria for improving antiphospholipid syndrome research

by Hospital for Special SurgeryCredit: CC0 Public DomainAn international team of more than 80 collaborators led by Hospital for Special Surgery (HSS) investigators is developing new classificatio

Updated on:March 26,2024

New algorithm may greatly speed up the design of 'humanized' antibodies that work

by Weizmann Institute of Science3D structure of an antibody’s “finger,” the portion that binds to a target. The colored regions are responsible for recognizing the target; the gray regions provid

Updated on: March 07,2024

New algorithm may greatly speed up the design of 'humanized' antibodies that work

by Weizmann Institute of Science3D structure of an antibody’s “finger,” the portion that binds to a target. The colored regions are responsible for recognizing the target; the gray regions provid

Updated on:March 07,2024

RNA proofreading mistakes drive group of autoimmune diseases

by The Scripps Research InstituteScripps Research Professor Patrick Griffin, PhD, of Jupiter, Florida, co-chairman of the Department of Molecular Medicine, used hydrogen-deuterium exchange mass s

Updated on: April 22,2024

RNA proofreading mistakes drive group of autoimmune diseases

by The Scripps Research InstituteScripps Research Professor Patrick Griffin, PhD, of Jupiter, Florida, co-chairman of the Department of Molecular Medicine, used hydrogen-deuterium exchange mass s

Updated on:April 22,2024

Immune receptor thought to be linked to hearing loss in child cancer survivors confirmed in new study

by Yolanda Poffenroth, Michael Brown,University of AlbertaCredit: Pixabay/CC0 Public DomainPermanent hearing loss triggered by a common chemotherapy drug in half of children being treated for ca

Updated on: May 07,2024

Immune receptor thought to be linked to hearing loss in child cancer survivors confirmed in new study

by Yolanda Poffenroth, Michael Brown,University of AlbertaCredit: Pixabay/CC0 Public DomainPermanent hearing loss triggered by a common chemotherapy drug in half of children being treated for ca

Updated on:May 07,2024

Discriminatory redlining practices in the 1930s associated with present-day rates of ED visits due to asthma

by LancetCredit: CC0 Public DomainCurrent rates of emergency department visits due to asthma are around 2.4 times higher in areas that were redlined—deprioritised for mortgage investment—in the 1

Updated on: April 02,2024

Discriminatory redlining practices in the 1930s associated with present-day rates of ED visits due to asthma

by LancetCredit: CC0 Public DomainCurrent rates of emergency department visits due to asthma are around 2.4 times higher in areas that were redlined—deprioritised for mortgage investment—in the 1

Updated on:April 02,2024

CARv3-TEAM-E T-cell treatment beneficial for recurrent glioblastoma

by Elana GotkineFor patients with recurrent glioblastoma, treatment with chimeric antigen receptor (CAR) T-cells engineered to target the epidermal growth factor receptor (EGFR) variant III tumor-spec

Updated on: March 27,2024

CARv3-TEAM-E T-cell treatment beneficial for recurrent glioblastoma

by Elana GotkineFor patients with recurrent glioblastoma, treatment with chimeric antigen receptor (CAR) T-cells engineered to target the epidermal growth factor receptor (EGFR) variant III tumor-spec

Updated on:March 27,2024

Researchers validate pediatric 'allergic march' in largest national study of its kind

byChildren's Hospital of PhiladelphiaCredit: Unsplash/CC0 Public DomainIn the largest study of its kind, researchers from Children's Hospital of Philadelphia (CHOP) used electronic healt

Updated on: March 05,2024

Researchers validate pediatric 'allergic march' in largest national study of its kind

byChildren's Hospital of PhiladelphiaCredit: Unsplash/CC0 Public DomainIn the largest study of its kind, researchers from Children's Hospital of Philadelphia (CHOP) used electronic healt

Updated on:March 05,2024

RNA as a future cure for hereditary diseases

by Fabio Bergamin,ETH ZurichOnly a handful of genetic diseases can be treated with drugs (symbolic image). One of several therapeutic approaches is based on RNA molecules. Credit: Science Photo

Updated on: April 22,2024

RNA as a future cure for hereditary diseases

by Fabio Bergamin,ETH ZurichOnly a handful of genetic diseases can be treated with drugs (symbolic image). One of several therapeutic approaches is based on RNA molecules. Credit: Science Photo

Updated on:April 22,2024

CAR T cell therapy effective as first-line treatment for high-risk large B-cell lymphoma

by University of Texas M. D. Anderson Cancer CenterCredit: CC0 Public DomainA study led by researchers at The University of Texas MD Anderson Cancer Center found that axi-cel, an autologous anti-

Updated on: April 09,2024

CAR T cell therapy effective as first-line treatment for high-risk large B-cell lymphoma

by University of Texas M. D. Anderson Cancer CenterCredit: CC0 Public DomainA study led by researchers at The University of Texas MD Anderson Cancer Center found that axi-cel, an autologous anti-

Updated on:April 09,2024

Three-dimensional label-free morphology of CD8+ T cells as a sepsis biomarker

by Chinese Academy of Sciencesa, Schematic overview of the study workflow. Blood was sampled three times in the sepsis recovery cohort and once in the healthy control cohort. CD8+ T cells were ex

Updated on: April 09,2024

Three-dimensional label-free morphology of CD8+ T cells as a sepsis biomarker

by Chinese Academy of Sciencesa, Schematic overview of the study workflow. Blood was sampled three times in the sepsis recovery cohort and once in the healthy control cohort. CD8+ T cells were ex

Updated on:April 09,2024

Treatment options for patients whose blood cancer relapses after CAR-T cell therapy

by The Mount Sinai HospitalCredit: Pixabay/CC0 Public DomainMount Sinai and Memorial Sloan Kettering Cancer Center (MSK) researchers have identified therapies that can help patients with the bloo

Updated on: April 09,2024

Treatment options for patients whose blood cancer relapses after CAR-T cell therapy

by The Mount Sinai HospitalCredit: Pixabay/CC0 Public DomainMount Sinai and Memorial Sloan Kettering Cancer Center (MSK) researchers have identified therapies that can help patients with the bloo

Updated on:April 09,2024