Research identifies protein that protects healthy joints from osteoarthritis

by University of DelawareThe blue area is the cell nucleus, the white area is F-actin, the structural scaffolding of the cells. Researchers discovered adseverin regulates the amount of F-actin in

Updated on: May 26,2024 6

Research identifies protein that protects healthy joints from osteoarthritis

by University of DelawareThe blue area is the cell nucleus, the white area is F-actin, the structural scaffolding of the cells. Researchers discovered adseverin regulates the amount of F-actin in

Updated on:May 26,2024 6

For arthritis in the big toe, surgeons offer new option

by Tom AvrilCredit: CC0 Public DomainThe big toe on Pattie Bostick-Winn's right foot was excruciatingly painful, likely the result of her 10 years as a professional dancer in Broadway-style shows.

Updated on: May 26,2024 4

For arthritis in the big toe, surgeons offer new option

by Tom AvrilCredit: CC0 Public DomainThe big toe on Pattie Bostick-Winn's right foot was excruciatingly painful, likely the result of her 10 years as a professional dancer in Broadway-style shows.

Updated on:May 26,2024 4

Antibiotic usage associated with increased risk of rheumatoid arthritis

by Andrew Cain,Keele UniversityCredit: CC0 Public DomainA new study has provided evidence that antibiotic usage is associated with an increased risk of developing rheumatoid arthritis.Researcher

Updated on: March 24,2024 16

Antibiotic usage associated with increased risk of rheumatoid arthritis

by Andrew Cain,Keele UniversityCredit: CC0 Public DomainA new study has provided evidence that antibiotic usage is associated with an increased risk of developing rheumatoid arthritis.Researcher

Updated on:March 24,2024 16

FDA approves 1st drug for moderate and severe eczema cases

by Linda A. JohnsonThis image provided by Sanofi shows a box containing two single-dose pre-filled syringes of the drug Dupixent. On Tuesday, March 28, 2017, the Food and Drug Administration approved

Updated on: April 15,2024 20

FDA approves 1st drug for moderate and severe eczema cases

by Linda A. JohnsonThis image provided by Sanofi shows a box containing two single-dose pre-filled syringes of the drug Dupixent. On Tuesday, March 28, 2017, the Food and Drug Administration approved

Updated on:April 15,2024 20

Oral deucravacitinib benefits patients with lupus

by WileyCredit: CC0 Public DomainTyrosine kinases are enzymes that play central roles in signaling by cytokines involved in the pathogenesis of autoimmune diseases, including lupus. A recent phas

Updated on: June 06,2024 5

Oral deucravacitinib benefits patients with lupus

by WileyCredit: CC0 Public DomainTyrosine kinases are enzymes that play central roles in signaling by cytokines involved in the pathogenesis of autoimmune diseases, including lupus. A recent phas

Updated on:June 06,2024 5

Systemic inflammation increases risk for chronic kidney disease

by Lori SolomonSystemic inflammation is associated with an elevated risk for chronic kidney disease, according to a study published online Feb. 20 inFrontiers in Immunology.Xiaoxin Liu, from Ton

Updated on: April 30,2024 0

Systemic inflammation increases risk for chronic kidney disease

by Lori SolomonSystemic inflammation is associated with an elevated risk for chronic kidney disease, according to a study published online Feb. 20 inFrontiers in Immunology.Xiaoxin Liu, from Ton

Updated on:April 30,2024 0

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on: April 16,2024 11

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on:April 16,2024 11

The double face of RNase as a treatment for systemic autoimmune diseases

by Osaka UniversityThe RNA-degrading enzyme enhances the function of immune complexes formed by autoantibodies against Ro/SSA and La/SSB antigens. Credit: Ryota Naito et al. JCI Insight 2023Syste

Updated on: April 22,2024 20

The double face of RNase as a treatment for systemic autoimmune diseases

by Osaka UniversityThe RNA-degrading enzyme enhances the function of immune complexes formed by autoantibodies against Ro/SSA and La/SSB antigens. Credit: Ryota Naito et al. JCI Insight 2023Syste

Updated on:April 22,2024 20

A novel animal model for analysing human natural killer cell functions in vivo

by Kawasaki CityFigure 1: Humanized mice were generated by transplanting 2.5 x 104 human cord blood-derived CD34+ HSC cells into irradiated NOG-IL-2 mice. After human CD34+ cell transplantation, human

Updated on: March 25,2024 20

A novel animal model for analysing human natural killer cell functions in vivo

by Kawasaki CityFigure 1: Humanized mice were generated by transplanting 2.5 x 104 human cord blood-derived CD34+ HSC cells into irradiated NOG-IL-2 mice. After human CD34+ cell transplantation, human

Updated on:March 25,2024 20

STIM-mediated calcium influx regulates maintenance and selection of germinal center B cells: Study

by Osaka UniversityCredit:Journal of Experimental Medicine(2023). DOI: 10.1084/jem.20222178Germinal centers (GCs) are specialized microenvironments where antigen (Ag)-specific B cells

Updated on: April 22,2024 13

STIM-mediated calcium influx regulates maintenance and selection of germinal center B cells: Study

by Osaka UniversityCredit:Journal of Experimental Medicine(2023). DOI: 10.1084/jem.20222178Germinal centers (GCs) are specialized microenvironments where antigen (Ag)-specific B cells

Updated on:April 22,2024 13

'JEDI' technology awakens new understanding of how immune system works

by The Mount Sinai Hospital3D rendering of a T cell. Credit: CC BY 3.0, Blausen.com staff. "Blausen gallery 2014". Wikiversity Journal of Medicine. DOI:10.15347/wjm/2014.010. ISSN 20018

Updated on: April 16,2024 18

'JEDI' technology awakens new understanding of how immune system works

by The Mount Sinai Hospital3D rendering of a T cell. Credit: CC BY 3.0, Blausen.com staff. "Blausen gallery 2014". Wikiversity Journal of Medicine. DOI:10.15347/wjm/2014.010. ISSN 20018

Updated on:April 16,2024 18

New strategy for COVID-19 prophylaxis

by University of BonnPhD student Samira Marx and Prof. Dr. Gunther Hartmann - of the Cluster of Excellence ImmunoSensation2 at the University of Bonn in the lab. Credit: David FußhöllerSARS-CoV-2

Updated on: April 13,2024 13

New strategy for COVID-19 prophylaxis

by University of BonnPhD student Samira Marx and Prof. Dr. Gunther Hartmann - of the Cluster of Excellence ImmunoSensation2 at the University of Bonn in the lab. Credit: David FußhöllerSARS-CoV-2

Updated on:April 13,2024 13