Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on: March 07,2024 18

Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on:March 07,2024 18

RNA as a future cure for hereditary diseases

by Fabio Bergamin,ETH ZurichOnly a handful of genetic diseases can be treated with drugs (symbolic image). One of several therapeutic approaches is based on RNA molecules. Credit: Science Photo

Updated on: April 22,2024 13

RNA as a future cure for hereditary diseases

by Fabio Bergamin,ETH ZurichOnly a handful of genetic diseases can be treated with drugs (symbolic image). One of several therapeutic approaches is based on RNA molecules. Credit: Science Photo

Updated on:April 22,2024 13

Scientists discover a rare missense variant in STAT6 that protects against asthma

by deCODE geneticsp.L406P is a partial LOF variant. Credit:Journal of Allergy and Clinical Immunology(2024). DOI: 10.1016/j.jaci.2024.10.002Scientists at deCODE genetics and collaborators

Updated on: November 22,2024 0

Scientists discover a rare missense variant in STAT6 that protects against asthma

by deCODE geneticsp.L406P is a partial LOF variant. Credit:Journal of Allergy and Clinical Immunology(2024). DOI: 10.1016/j.jaci.2024.10.002Scientists at deCODE genetics and collaborators

Updated on:November 22,2024 0

New analysis finds belimumab improves cutaneous lupus erythematosus in patients with or without SLE

by American College of RheumatologyForest plot of clinical response in CLE with or without SLE in belimumab users vs. non-users at week 52. Credit: Significant Improvement in Cutaneous Lupus Eryt

Updated on: May 29,2024 6

New analysis finds belimumab improves cutaneous lupus erythematosus in patients with or without SLE

by American College of RheumatologyForest plot of clinical response in CLE with or without SLE in belimumab users vs. non-users at week 52. Credit: Significant Improvement in Cutaneous Lupus Eryt

Updated on:May 29,2024 6

Compound in green tea found to block rheumatoid arthritis

by Washington State UniversityGreen tea. Credit: Wikimedia CommonsResearchers at Washington State University in Spokane have identified a potential new approach to combating the joint pain, infla

Updated on: April 08,2024 20

Compound in green tea found to block rheumatoid arthritis

by Washington State UniversityGreen tea. Credit: Wikimedia CommonsResearchers at Washington State University in Spokane have identified a potential new approach to combating the joint pain, infla

Updated on:April 08,2024 20

Oral deucravacitinib benefits patients with lupus

by WileyCredit: CC0 Public DomainTyrosine kinases are enzymes that play central roles in signaling by cytokines involved in the pathogenesis of autoimmune diseases, including lupus. A recent phas

Updated on: June 06,2024 5

Oral deucravacitinib benefits patients with lupus

by WileyCredit: CC0 Public DomainTyrosine kinases are enzymes that play central roles in signaling by cytokines involved in the pathogenesis of autoimmune diseases, including lupus. A recent phas

Updated on:June 06,2024 5

Once considered rare, an itchy dermatologic skin disorder is more common than thought

by Johns Hopkins UniversityCredit: CC0 Public DomainJohns Hopkins researchers report that prurigo nodularis (PN), a skin disease characterized by severely itchy, firm bumps on the skin, may be as

Updated on: April 24,2024 18

Once considered rare, an itchy dermatologic skin disorder is more common than thought

by Johns Hopkins UniversityCredit: CC0 Public DomainJohns Hopkins researchers report that prurigo nodularis (PN), a skin disease characterized by severely itchy, firm bumps on the skin, may be as

Updated on:April 24,2024 18

A new pathway to 'reprogram' killer cells

by University of BernNK cells (brown) patrolling between cells of a healthy human lymph node. Credit: Institute of Pathology, University of BernThe so-called natural killer (NK) cells are cells o

Updated on: May 08,2024 4

A new pathway to 'reprogram' killer cells

by University of BernNK cells (brown) patrolling between cells of a healthy human lymph node. Credit: Institute of Pathology, University of BernThe so-called natural killer (NK) cells are cells o

Updated on:May 08,2024 4

Certain criteria may be better than others in RA assessment

(HealthDay)—For patients with rheumatoid arthritis (RA), the performances of the Clinical Disease Activity Index (CDAI) and Simplified Disease Activity Index (SDAI) appear to be better than that of th

Updated on: March 30,2024 13

Certain criteria may be better than others in RA assessment

(HealthDay)—For patients with rheumatoid arthritis (RA), the performances of the Clinical Disease Activity Index (CDAI) and Simplified Disease Activity Index (SDAI) appear to be better than that of th

Updated on:March 30,2024 13

How much of a boost do 'booster' COVID-19 jabs give?

by King's College LondonCredit: Pixabay/CC0 Public DomainScientists have found the "booster" COVID-19 vaccine program led to a large boost in the antibodies that help protect agains

Updated on: March 13,2024 19

How much of a boost do 'booster' COVID-19 jabs give?

by King's College LondonCredit: Pixabay/CC0 Public DomainScientists have found the "booster" COVID-19 vaccine program led to a large boost in the antibodies that help protect agains

Updated on:March 13,2024 19

A fresh look at joint inflammation in rheumatoid arthritis patients

by Trinity College DublinCredit: Unsplash/CC0 Public DomainResearchers at Trinity are providing fresh insights into joint inflammation in patients with rheumatoid arthritis (RA). The condition cu

Updated on: June 11,2024 5

A fresh look at joint inflammation in rheumatoid arthritis patients

by Trinity College DublinCredit: Unsplash/CC0 Public DomainResearchers at Trinity are providing fresh insights into joint inflammation in patients with rheumatoid arthritis (RA). The condition cu

Updated on:June 11,2024 5

Indoor allergens worsen respiratory infections in children with asthma, study finds

byUniversity of Texas at AustinCredit: Andrea Piacquadio from PexelsChildren with asthma who are exposed to high levels of indoor allergens, such as cockroach and mouse allergens, are at an incr

Updated on: September 18,2024 0

Indoor allergens worsen respiratory infections in children with asthma, study finds

byUniversity of Texas at AustinCredit: Andrea Piacquadio from PexelsChildren with asthma who are exposed to high levels of indoor allergens, such as cockroach and mouse allergens, are at an incr

Updated on:September 18,2024 0