Combined inhibition of TNF-alpha, IL-17 effective in RA model

(HealthDay)—Combined inhibition of tumor necrosis factor (TNF) α and interleukin (IL)-17 is more effective than single blockade in cultures of human fibroblast-like synoviocytes (FLS), according to an

Updated on: April 08,2024 11

Combined inhibition of TNF-alpha, IL-17 effective in RA model

(HealthDay)—Combined inhibition of tumor necrosis factor (TNF) α and interleukin (IL)-17 is more effective than single blockade in cultures of human fibroblast-like synoviocytes (FLS), according to an

Updated on:April 08,2024 11

Study sheds light on pregnancy complications and overturns common belief

by Hospital for Special Surgery"Many doctors may be unnecessarily treating some pregnant women who have antiphospholipid antibodies (aPLs) with anticoagulants, such as expensive heparin inje

Updated on: April 17,2024 14

Study sheds light on pregnancy complications and overturns common belief

by Hospital for Special Surgery"Many doctors may be unnecessarily treating some pregnant women who have antiphospholipid antibodies (aPLs) with anticoagulants, such as expensive heparin inje

Updated on:April 17,2024 14

Sex-specific immune response in COVID-19 linked to cellular metabolism

by Rick Harrison,Yale UniversityImage of the ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV). Credit: CDCResearchers studying COVID-19 patients have found a metabo

Updated on: April 13,2024 12

Sex-specific immune response in COVID-19 linked to cellular metabolism

by Rick Harrison,Yale UniversityImage of the ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV). Credit: CDCResearchers studying COVID-19 patients have found a metabo

Updated on:April 13,2024 12

Study examines care received by patients with knee osteoarthritis

by WileyCredit: CC0 Public DomainNew research reveals that only a minority of U.S. Medicare beneficiaries with knee osteoarthritis in 2005-2010 used non-surgical care such as physical therapy and

Updated on: May 19,2024 5

Study examines care received by patients with knee osteoarthritis

by WileyCredit: CC0 Public DomainNew research reveals that only a minority of U.S. Medicare beneficiaries with knee osteoarthritis in 2005-2010 used non-surgical care such as physical therapy and

Updated on:May 19,2024 5

TET proteins regulate factors essential for normal antibody production

by La Jolla Institute for ImmunologyMutant B cells lacking TET2 and TET3 produce an overabundance of a class of antibody called IgM, whereas normal control B cells churned out more effective antibodie

Updated on: April 24,2024 20

TET proteins regulate factors essential for normal antibody production

by La Jolla Institute for ImmunologyMutant B cells lacking TET2 and TET3 produce an overabundance of a class of antibody called IgM, whereas normal control B cells churned out more effective antibodie

Updated on:April 24,2024 20

Allergy diary' phone app classifies phenotypes in rhinitis

(HealthDay)—TheAllergy Diaryphone app can identify phenotypic differences between rhinitis groups, according to a study published online Jan. 10 inAllergy.Jean Bousquet, M.D., from t

Updated on: March 13,2024 12

Allergy diary' phone app classifies phenotypes in rhinitis

(HealthDay)—TheAllergy Diaryphone app can identify phenotypic differences between rhinitis groups, according to a study published online Jan. 10 inAllergy.Jean Bousquet, M.D., from t

Updated on:March 13,2024 12

An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on: March 30,2024 8

An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on:March 30,2024 8

A gene that plays a critical role in natural killer cell differentiation

by Bob Yirka , Medical XpressAn illustration of natural killer cells. Credit: Val Altounian / AAASA large team of researchers affiliated with a host of institutions in Europe and the U.S. has found a

Updated on: March 25,2024 17

A gene that plays a critical role in natural killer cell differentiation

by Bob Yirka , Medical XpressAn illustration of natural killer cells. Credit: Val Altounian / AAASA large team of researchers affiliated with a host of institutions in Europe and the U.S. has found a

Updated on:March 25,2024 17

A mathematical model that predicts how severe hay fever season will be

by Bob Yirka , Medical XpressCredit: Pixabay/CC0 Public DomainAn international team of researchers has developed a mathematical model for predicting how bad an upcoming hay fever season will be. In th

Updated on: May 07,2024 10

A mathematical model that predicts how severe hay fever season will be

by Bob Yirka , Medical XpressCredit: Pixabay/CC0 Public DomainAn international team of researchers has developed a mathematical model for predicting how bad an upcoming hay fever season will be. In th

Updated on:May 07,2024 10

Clinical trial denounces use of platelet-rich plasma injections for knee joint osteoarthritis

by University of MelbournePlatelet-rich plasma injections have become a popular form of treatment for painful joints in recent years but researchers have established they are no better than place

Updated on: April 20,2024 14

Clinical trial denounces use of platelet-rich plasma injections for knee joint osteoarthritis

by University of MelbournePlatelet-rich plasma injections have become a popular form of treatment for painful joints in recent years but researchers have established they are no better than place

Updated on:April 20,2024 14

Immune system's moonlighters point the way to a new therapeutic target

FEBRUARY 20, 2024byCold Spring Harbor LaboratoryGraphical abstract. Credit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.01.007Our immune system is remarkably powerful. It quickly

Updated on: March 25,2024 5

Immune system's moonlighters point the way to a new therapeutic target

FEBRUARY 20, 2024byCold Spring Harbor LaboratoryGraphical abstract. Credit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.01.007Our immune system is remarkably powerful. It quickly

Updated on:March 25,2024 5

Immune receptor thought to be linked to hearing loss in child cancer survivors confirmed in new study

by Yolanda Poffenroth, Michael Brown,University of AlbertaCredit: Pixabay/CC0 Public DomainPermanent hearing loss triggered by a common chemotherapy drug in half of children being treated for ca

Updated on: May 07,2024 16

Immune receptor thought to be linked to hearing loss in child cancer survivors confirmed in new study

by Yolanda Poffenroth, Michael Brown,University of AlbertaCredit: Pixabay/CC0 Public DomainPermanent hearing loss triggered by a common chemotherapy drug in half of children being treated for ca

Updated on:May 07,2024 16