Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on: March 07,2024

Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on:March 07,2024

How do MAIT cells identify and attack foreign invaders?

byUniversity of MelbourneCredit: CC0 Public DomainMelbourne researchers have identified what makes a specialised immune cell, known as mucosal-associated invariant T (MAIT), cells boost their nu

Updated on: April 20,2024

How do MAIT cells identify and attack foreign invaders?

byUniversity of MelbourneCredit: CC0 Public DomainMelbourne researchers have identified what makes a specialised immune cell, known as mucosal-associated invariant T (MAIT), cells boost their nu

Updated on:April 20,2024

Leflunomide considered safe, effective for psoriatic arthritis

Leflunomide is effective for the treatment of patients with psoriatic arthritis in daily clinical practice, according to a study published online Oct. 6 inArthritis Care & Research.(HealthDa

Updated on: April 08,2024

Leflunomide considered safe, effective for psoriatic arthritis

Leflunomide is effective for the treatment of patients with psoriatic arthritis in daily clinical practice, according to a study published online Oct. 6 inArthritis Care & Research.(HealthDa

Updated on:April 08,2024

Preclinical study of COVID-19 vaccine candidate shows potent T-cell responses

by University of Alabama at BirminghamCredit: University of Alabama at BirminghamPreclinical studies of a COVID-19 vaccine candidate at the University of Alabama at Birmingham show positive resul

Updated on: April 10,2024

Preclinical study of COVID-19 vaccine candidate shows potent T-cell responses

by University of Alabama at BirminghamCredit: University of Alabama at BirminghamPreclinical studies of a COVID-19 vaccine candidate at the University of Alabama at Birmingham show positive resul

Updated on:April 10,2024

An existing drug may change tumor-associated macrophages back to cancer fighters

by Jeff Hansen,University of Alabama at BirminghamCredit: Unsplash/CC0 Public DomainA form of cell communication called hedgehog signaling is vital for embryonic development in mammals. Bu

Updated on: March 26,2024

An existing drug may change tumor-associated macrophages back to cancer fighters

by Jeff Hansen,University of Alabama at BirminghamCredit: Unsplash/CC0 Public DomainA form of cell communication called hedgehog signaling is vital for embryonic development in mammals. Bu

Updated on:March 26,2024

Eyes serve as immunological barrier in fight against brain pathogens, finds study

by Yale University10x VISIUM Spatial sequencing of the mouse globe and optic nerve. Mouse eyes were processed using traditional FFPE-based histology preparation. Samples were processed using the

Updated on: March 07,2024

Eyes serve as immunological barrier in fight against brain pathogens, finds study

by Yale University10x VISIUM Spatial sequencing of the mouse globe and optic nerve. Mouse eyes were processed using traditional FFPE-based histology preparation. Samples were processed using the

Updated on:March 07,2024

Evolutionary study links subtle modifications in the morphology of the bipedal knee to osteoarthritis later in life

by Harvard UniversityA visual riff on the classic illustration, "March of Progress," highlighting the evolution of knee osteoarthritis. Credit: Tasha McAbee, Department of Orthopedics a

Updated on: May 08,2024

Evolutionary study links subtle modifications in the morphology of the bipedal knee to osteoarthritis later in life

by Harvard UniversityA visual riff on the classic illustration, "March of Progress," highlighting the evolution of knee osteoarthritis. Credit: Tasha McAbee, Department of Orthopedics a

Updated on:May 08,2024

Autoimmune diseases in ALS patients linked to genetic mutation

by Sarah Lichtman,Cedars-Sinai Medical CenterRobert Baloh, MD, PhD, at work in his laboratory. Credit: Cedars-SinaiA study published today in the journalNaturecould help explain why

Updated on: April 08,2024

Autoimmune diseases in ALS patients linked to genetic mutation

by Sarah Lichtman,Cedars-Sinai Medical CenterRobert Baloh, MD, PhD, at work in his laboratory. Credit: Cedars-SinaiA study published today in the journalNaturecould help explain why

Updated on:April 08,2024

Race, ethnic disparities seen in age-adjusted prevalence of arthritis

by Elana GotkineThe age-adjusted prevalence of arthritis varies by race and ethnicity, with higher prevalence seen among American Indian/Alaska Native adults, according to a studypublished

Updated on: July 23,2024

Race, ethnic disparities seen in age-adjusted prevalence of arthritis

by Elana GotkineThe age-adjusted prevalence of arthritis varies by race and ethnicity, with higher prevalence seen among American Indian/Alaska Native adults, according to a studypublished

Updated on:July 23,2024

Standardized treatment plans developed for new-onset JIA

Four standardized consensus treatment plans have been developed for patients with new-onset systemic juvenile idiopathic arthritis, according to research published in the July issue ofArthritis

Updated on: March 26,2024

Standardized treatment plans developed for new-onset JIA

Four standardized consensus treatment plans have been developed for patients with new-onset systemic juvenile idiopathic arthritis, according to research published in the July issue ofArthritis

Updated on:March 26,2024

Monash researchers bringing hope to lupus patients

by Monash UniversityResearchers at Monash University are leading the world's largest study to describe lupus patients and disease characteristics, bringing treat-to-target options for lupus a

Updated on: March 24,2024

Monash researchers bringing hope to lupus patients

by Monash UniversityResearchers at Monash University are leading the world's largest study to describe lupus patients and disease characteristics, bringing treat-to-target options for lupus a

Updated on:March 24,2024

Study shows autoantibodies behind lifelong risk of viral infection

byUniversity of ZurichCredit: CC0 Public DomainA new study,publishedin theJournal of Experimental Medicine, shows that about 2% of the population develop autoantibodies against

Updated on: July 30,2024

Study shows autoantibodies behind lifelong risk of viral infection

byUniversity of ZurichCredit: CC0 Public DomainA new study,publishedin theJournal of Experimental Medicine, shows that about 2% of the population develop autoantibodies against

Updated on:July 30,2024