Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on: May 14,2024

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on:May 14,2024

Leflunomide considered safe, effective for psoriatic arthritis

Leflunomide is effective for the treatment of patients with psoriatic arthritis in daily clinical practice, according to a study published online Oct. 6 inArthritis Care & Research.(HealthDa

Updated on: April 08,2024

Leflunomide considered safe, effective for psoriatic arthritis

Leflunomide is effective for the treatment of patients with psoriatic arthritis in daily clinical practice, according to a study published online Oct. 6 inArthritis Care & Research.(HealthDa

Updated on:April 08,2024

An unconventional ion channel

by Ludwig Maximilian University of MunichTRPML2 channels (green) on vacuolin-enlarged fast recycling vesicles (positive for the fast-recycling marker RAB4A (red)), permitting to microdissect thes

Updated on: April 24,2024

An unconventional ion channel

by Ludwig Maximilian University of MunichTRPML2 channels (green) on vacuolin-enlarged fast recycling vesicles (positive for the fast-recycling marker RAB4A (red)), permitting to microdissect thes

Updated on:April 24,2024

How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on: March 27,2024

How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on:March 27,2024

Standardized treatment plans developed for new-onset JIA

Four standardized consensus treatment plans have been developed for patients with new-onset systemic juvenile idiopathic arthritis, according to research published in the July issue ofArthritis

Updated on: March 26,2024

Standardized treatment plans developed for new-onset JIA

Four standardized consensus treatment plans have been developed for patients with new-onset systemic juvenile idiopathic arthritis, according to research published in the July issue ofArthritis

Updated on:March 26,2024

Myogenes identified for spondyloarthritis synovitis

There are disease-specific and inflammation-independent stromal alterations in spondyloarthritis synovitis, according to a study published online Sept. 12 inArthritis & Rheumatism.(HealthDay

Updated on: April 08,2024

Myogenes identified for spondyloarthritis synovitis

There are disease-specific and inflammation-independent stromal alterations in spondyloarthritis synovitis, according to a study published online Sept. 12 inArthritis & Rheumatism.(HealthDay

Updated on:April 08,2024

Researchers discover immune system changes that support peanut allergy remission in children

by Murdoch Children's Research InstituteResearchers have discovered the key immunological changes that support the remission of peanut allergy in children, paving the way for new, more target

Updated on: May 05,2024

Researchers discover immune system changes that support peanut allergy remission in children

by Murdoch Children's Research InstituteResearchers have discovered the key immunological changes that support the remission of peanut allergy in children, paving the way for new, more target

Updated on:May 05,2024

Scientists warn of a 'tsunami' of osteoarthritis cases by 2050

by European Cooperation in Science and Technology (COST)View of the knee joint; 3D reconstruction of articular structures based on magnetic resonance imaging (MRI) and segmentation: with permission fr

Updated on: March 27,2024

Scientists warn of a 'tsunami' of osteoarthritis cases by 2050

by European Cooperation in Science and Technology (COST)View of the knee joint; 3D reconstruction of articular structures based on magnetic resonance imaging (MRI) and segmentation: with permission fr

Updated on:March 27,2024

A common skin bacterium put children with severe eczema at higher risk of food allergy

by King's College LondonCredit: CC0 Public DomainIn a new study published today in theJournal of Allergy and Clinical Immunology, scientists from King's College London have found th

Updated on: May 08,2024

A common skin bacterium put children with severe eczema at higher risk of food allergy

by King's College LondonCredit: CC0 Public DomainIn a new study published today in theJournal of Allergy and Clinical Immunology, scientists from King's College London have found th

Updated on:May 08,2024

Autoimmune diseases in ALS patients linked to genetic mutation

by Sarah Lichtman,Cedars-Sinai Medical CenterRobert Baloh, MD, PhD, at work in his laboratory. Credit: Cedars-SinaiA study published today in the journalNaturecould help explain why

Updated on: April 08,2024

Autoimmune diseases in ALS patients linked to genetic mutation

by Sarah Lichtman,Cedars-Sinai Medical CenterRobert Baloh, MD, PhD, at work in his laboratory. Credit: Cedars-SinaiA study published today in the journalNaturecould help explain why

Updated on:April 08,2024

Smoking impairs treatment response in inflammatory back arthritis

by British Medical JournalSmoking harms nearly every organ in the body and causes many diseases. Credit: CDC/Debora CartagenaSmoking impairs the response to biological drugs used to treat inflamm

Updated on: May 13,2024

Smoking impairs treatment response in inflammatory back arthritis

by British Medical JournalSmoking harms nearly every organ in the body and causes many diseases. Credit: CDC/Debora CartagenaSmoking impairs the response to biological drugs used to treat inflamm

Updated on:May 13,2024

How a virus that infects 50% of people is helping develop new cancer treatments

by Rebecca Aicheler,The ConversationCredit: AI-generated imageMost of us have heard of viruses such asmeaslesandmumps—not to mention the more seriousHIVandEbo

Updated on: May 07,2024

How a virus that infects 50% of people is helping develop new cancer treatments

by Rebecca Aicheler,The ConversationCredit: AI-generated imageMost of us have heard of viruses such asmeaslesandmumps—not to mention the more seriousHIVandEbo

Updated on:May 07,2024