An unconventional ion channel

by Ludwig Maximilian University of MunichTRPML2 channels (green) on vacuolin-enlarged fast recycling vesicles (positive for the fast-recycling marker RAB4A (red)), permitting to microdissect thes

Updated on: April 24,2024

An unconventional ion channel

by Ludwig Maximilian University of MunichTRPML2 channels (green) on vacuolin-enlarged fast recycling vesicles (positive for the fast-recycling marker RAB4A (red)), permitting to microdissect thes

Updated on:April 24,2024

Eyes serve as immunological barrier in fight against brain pathogens, finds study

by Yale University10x VISIUM Spatial sequencing of the mouse globe and optic nerve. Mouse eyes were processed using traditional FFPE-based histology preparation. Samples were processed using the

Updated on: March 07,2024

Eyes serve as immunological barrier in fight against brain pathogens, finds study

by Yale University10x VISIUM Spatial sequencing of the mouse globe and optic nerve. Mouse eyes were processed using traditional FFPE-based histology preparation. Samples were processed using the

Updated on:March 07,2024

Autoimmune diseases in ALS patients linked to genetic mutation

by Sarah Lichtman,Cedars-Sinai Medical CenterRobert Baloh, MD, PhD, at work in his laboratory. Credit: Cedars-SinaiA study published today in the journalNaturecould help explain why

Updated on: April 08,2024

Autoimmune diseases in ALS patients linked to genetic mutation

by Sarah Lichtman,Cedars-Sinai Medical CenterRobert Baloh, MD, PhD, at work in his laboratory. Credit: Cedars-SinaiA study published today in the journalNaturecould help explain why

Updated on:April 08,2024

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on: May 14,2024

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on:May 14,2024

CAR-T cell therapy leads to long-term remission in lupus while maintaining vaccine response

by American College of RheumatologyCredit: CC0 Public DomainNew researchatACR Convergence 2023, the American College of Rheumatology's annual meeting, demonstrates that CAR-T cell

Updated on: April 09,2024

CAR-T cell therapy leads to long-term remission in lupus while maintaining vaccine response

by American College of RheumatologyCredit: CC0 Public DomainNew researchatACR Convergence 2023, the American College of Rheumatology's annual meeting, demonstrates that CAR-T cell

Updated on:April 09,2024

How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on: March 27,2024

How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on:March 27,2024

A common skin bacterium put children with severe eczema at higher risk of food allergy

by King's College LondonCredit: CC0 Public DomainIn a new study published today in theJournal of Allergy and Clinical Immunology, scientists from King's College London have found th

Updated on: May 08,2024

A common skin bacterium put children with severe eczema at higher risk of food allergy

by King's College LondonCredit: CC0 Public DomainIn a new study published today in theJournal of Allergy and Clinical Immunology, scientists from King's College London have found th

Updated on:May 08,2024

Study examines care received by patients with knee osteoarthritis

by WileyCredit: CC0 Public DomainNew research reveals that only a minority of U.S. Medicare beneficiaries with knee osteoarthritis in 2005-2010 used non-surgical care such as physical therapy and

Updated on: May 19,2024

Study examines care received by patients with knee osteoarthritis

by WileyCredit: CC0 Public DomainNew research reveals that only a minority of U.S. Medicare beneficiaries with knee osteoarthritis in 2005-2010 used non-surgical care such as physical therapy and

Updated on:May 19,2024

Moms with systemic lupus erythematosus at double the risk of having premature or growth-restricted babies, finds study

by British Medical JournalCredit: Unsplash/CC0 Public DomainMothers with the long term autoimmune disorder, systemic lupus erythematosus, or SLE for short, run more than double the risk of giving

Updated on: June 05,2024

Moms with systemic lupus erythematosus at double the risk of having premature or growth-restricted babies, finds study

by British Medical JournalCredit: Unsplash/CC0 Public DomainMothers with the long term autoimmune disorder, systemic lupus erythematosus, or SLE for short, run more than double the risk of giving

Updated on:June 05,2024

Spike proteins of SARS-CoV-2 relatives can evolve against immune responses

by eLifeNovel Coronavirus SARS-CoV-2 Transmission electron micrograph of SARS-CoV-2 virus particles, isolated from a patient. Image captured and color-enhanced at the NIAID Integrated Research Fa

Updated on: April 22,2024

Spike proteins of SARS-CoV-2 relatives can evolve against immune responses

by eLifeNovel Coronavirus SARS-CoV-2 Transmission electron micrograph of SARS-CoV-2 virus particles, isolated from a patient. Image captured and color-enhanced at the NIAID Integrated Research Fa

Updated on:April 22,2024

Researchers discover immune system changes that support peanut allergy remission in children

by Murdoch Children's Research InstituteResearchers have discovered the key immunological changes that support the remission of peanut allergy in children, paving the way for new, more target

Updated on: May 05,2024

Researchers discover immune system changes that support peanut allergy remission in children

by Murdoch Children's Research InstituteResearchers have discovered the key immunological changes that support the remission of peanut allergy in children, paving the way for new, more target

Updated on:May 05,2024

New device for low-cost single-cell analysis identifies fibroblast subtypes in rheumatoid arthritis patients

by New York Genome CenterResearchers at the New York Genome Center (NYGC) and New York University (NYU) have taken steps to facilitate broad access to single-cell sequencing by developing a 3-D-printe

Updated on: April 07,2024

New device for low-cost single-cell analysis identifies fibroblast subtypes in rheumatoid arthritis patients

by New York Genome CenterResearchers at the New York Genome Center (NYGC) and New York University (NYU) have taken steps to facilitate broad access to single-cell sequencing by developing a 3-D-printe

Updated on:April 07,2024