Immune system's moonlighters point the way to a new therapeutic target

FEBRUARY 20, 2024byCold Spring Harbor LaboratoryGraphical abstract. Credit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.01.007Our immune system is remarkably powerful. It quickly

Updated on: March 25,2024

Immune system's moonlighters point the way to a new therapeutic target

FEBRUARY 20, 2024byCold Spring Harbor LaboratoryGraphical abstract. Credit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.01.007Our immune system is remarkably powerful. It quickly

Updated on:March 25,2024

How one inflammatory disorder exacerbates another

by Katherine Unger Baillie,University of PennsylvaniaInflammation in the gums can increase susceptibility to other forms of inflammation, such as arthritis, through changes to immune cell precur

Updated on: March 25,2024

How one inflammatory disorder exacerbates another

by Katherine Unger Baillie,University of PennsylvaniaInflammation in the gums can increase susceptibility to other forms of inflammation, such as arthritis, through changes to immune cell precur

Updated on:March 25,2024

Surprise rheumatoid arthritis discovery points to new treatment for joint inflammation

by University of VirginiaCredit: Alexandra Angelich, University CommunicationsResearchers at the University of Virginia School of Medicine have identified an unexpected contributor to rheumatoid

Updated on: June 17,2024

Surprise rheumatoid arthritis discovery points to new treatment for joint inflammation

by University of VirginiaCredit: Alexandra Angelich, University CommunicationsResearchers at the University of Virginia School of Medicine have identified an unexpected contributor to rheumatoid

Updated on:June 17,2024

CAR-T cell therapy leads to long-term remission in lupus while maintaining vaccine response

by American College of RheumatologyCredit: CC0 Public DomainNew researchatACR Convergence 2023, the American College of Rheumatology's annual meeting, demonstrates that CAR-T cell

Updated on: April 09,2024

CAR-T cell therapy leads to long-term remission in lupus while maintaining vaccine response

by American College of RheumatologyCredit: CC0 Public DomainNew researchatACR Convergence 2023, the American College of Rheumatology's annual meeting, demonstrates that CAR-T cell

Updated on:April 09,2024

Eyes serve as immunological barrier in fight against brain pathogens, finds study

by Yale University10x VISIUM Spatial sequencing of the mouse globe and optic nerve. Mouse eyes were processed using traditional FFPE-based histology preparation. Samples were processed using the

Updated on: March 07,2024

Eyes serve as immunological barrier in fight against brain pathogens, finds study

by Yale University10x VISIUM Spatial sequencing of the mouse globe and optic nerve. Mouse eyes were processed using traditional FFPE-based histology preparation. Samples were processed using the

Updated on:March 07,2024

Current asthma at age 7 linked to chronic rhinosinusitis in middle age

by Elana GotkineCredit: Pixabay/CC0 Public DomainCurrent asthma, head colds, and tonsillitis at age 7 years are associated with chronic rhinosinusitis (CRS) at midlife, according to a studypubli

Updated on: July 17,2024

Current asthma at age 7 linked to chronic rhinosinusitis in middle age

by Elana GotkineCredit: Pixabay/CC0 Public DomainCurrent asthma, head colds, and tonsillitis at age 7 years are associated with chronic rhinosinusitis (CRS) at midlife, according to a studypubli

Updated on:July 17,2024

Visual illusion proves effective in relieving knee pain for people with osteoarthritis

by University of South AustraliaCredit: CC0 Public DomainIn a new study published in the journalPeer Jthis week, researchers at UniSA's Body in Mind Research Group have found peop

Updated on: April 17,2024

Visual illusion proves effective in relieving knee pain for people with osteoarthritis

by University of South AustraliaCredit: CC0 Public DomainIn a new study published in the journalPeer Jthis week, researchers at UniSA's Body in Mind Research Group have found peop

Updated on:April 17,2024

An unconventional ion channel

by Ludwig Maximilian University of MunichTRPML2 channels (green) on vacuolin-enlarged fast recycling vesicles (positive for the fast-recycling marker RAB4A (red)), permitting to microdissect thes

Updated on: April 24,2024

An unconventional ion channel

by Ludwig Maximilian University of MunichTRPML2 channels (green) on vacuolin-enlarged fast recycling vesicles (positive for the fast-recycling marker RAB4A (red)), permitting to microdissect thes

Updated on:April 24,2024

Three-dimensional label-free morphology of CD8+ T cells as a sepsis biomarker

by Chinese Academy of Sciencesa, Schematic overview of the study workflow. Blood was sampled three times in the sepsis recovery cohort and once in the healthy control cohort. CD8+ T cells were ex

Updated on: April 09,2024

Three-dimensional label-free morphology of CD8+ T cells as a sepsis biomarker

by Chinese Academy of Sciencesa, Schematic overview of the study workflow. Blood was sampled three times in the sepsis recovery cohort and once in the healthy control cohort. CD8+ T cells were ex

Updated on:April 09,2024

Combined inhibition of TNF-alpha, IL-17 effective in RA model

(HealthDay)—Combined inhibition of tumor necrosis factor (TNF) α and interleukin (IL)-17 is more effective than single blockade in cultures of human fibroblast-like synoviocytes (FLS), according to an

Updated on: April 08,2024

Combined inhibition of TNF-alpha, IL-17 effective in RA model

(HealthDay)—Combined inhibition of tumor necrosis factor (TNF) α and interleukin (IL)-17 is more effective than single blockade in cultures of human fibroblast-like synoviocytes (FLS), according to an

Updated on:April 08,2024

Physical activity and sleep in adults with arthritis

by WileyA new study published in Arthritis Care & Research has examined patterns of 24-hour physical activity and sleep among patients with rheumatoid arthritis, lupus, and knee osteoarthriti

Updated on: May 08,2024

Physical activity and sleep in adults with arthritis

by WileyA new study published in Arthritis Care & Research has examined patterns of 24-hour physical activity and sleep among patients with rheumatoid arthritis, lupus, and knee osteoarthriti

Updated on:May 08,2024

'Junk DNA' is a double-edged sword, and the good side has anti-cancer potential

by University of Rochester Medical CenterCredit: Pixabay/CC0 Public DomainRochester biologists show how selfish genetic elements that can cause tumors may also trigger the death of cancer cells.S

Updated on: March 13,2024

'Junk DNA' is a double-edged sword, and the good side has anti-cancer potential

by University of Rochester Medical CenterCredit: Pixabay/CC0 Public DomainRochester biologists show how selfish genetic elements that can cause tumors may also trigger the death of cancer cells.S

Updated on:March 13,2024