The secret lives of T cell receptors and their role in the immune response

by Delthia Ricks , Medical XpressCredit: CC0 Public DomainCanadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components inte

Updated on: May 05,2024

The secret lives of T cell receptors and their role in the immune response

by Delthia Ricks , Medical XpressCredit: CC0 Public DomainCanadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components inte

Updated on:May 05,2024

Evolutionary study links subtle modifications in the morphology of the bipedal knee to osteoarthritis later in life

by Harvard UniversityA visual riff on the classic illustration, "March of Progress," highlighting the evolution of knee osteoarthritis. Credit: Tasha McAbee, Department of Orthopedics a

Updated on: May 08,2024

Evolutionary study links subtle modifications in the morphology of the bipedal knee to osteoarthritis later in life

by Harvard UniversityA visual riff on the classic illustration, "March of Progress," highlighting the evolution of knee osteoarthritis. Credit: Tasha McAbee, Department of Orthopedics a

Updated on:May 08,2024

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on: May 14,2024

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on:May 14,2024

Researchers discover immune system changes that support peanut allergy remission in children

by Murdoch Children's Research InstituteResearchers have discovered the key immunological changes that support the remission of peanut allergy in children, paving the way for new, more target

Updated on: May 05,2024

Researchers discover immune system changes that support peanut allergy remission in children

by Murdoch Children's Research InstituteResearchers have discovered the key immunological changes that support the remission of peanut allergy in children, paving the way for new, more target

Updated on:May 05,2024

A novel animal model for analysing human natural killer cell functions in vivo

by Kawasaki CityFigure 1: Humanized mice were generated by transplanting 2.5 x 104 human cord blood-derived CD34+ HSC cells into irradiated NOG-IL-2 mice. After human CD34+ cell transplantation, human

Updated on: March 25,2024

A novel animal model for analysing human natural killer cell functions in vivo

by Kawasaki CityFigure 1: Humanized mice were generated by transplanting 2.5 x 104 human cord blood-derived CD34+ HSC cells into irradiated NOG-IL-2 mice. After human CD34+ cell transplantation, human

Updated on:March 25,2024

Autoimmune diseases in ALS patients linked to genetic mutation

by Sarah Lichtman,Cedars-Sinai Medical CenterRobert Baloh, MD, PhD, at work in his laboratory. Credit: Cedars-SinaiA study published today in the journalNaturecould help explain why

Updated on: April 08,2024

Autoimmune diseases in ALS patients linked to genetic mutation

by Sarah Lichtman,Cedars-Sinai Medical CenterRobert Baloh, MD, PhD, at work in his laboratory. Credit: Cedars-SinaiA study published today in the journalNaturecould help explain why

Updated on:April 08,2024

A new pathway to 'reprogram' killer cells

by University of BernNK cells (brown) patrolling between cells of a healthy human lymph node. Credit: Institute of Pathology, University of BernThe so-called natural killer (NK) cells are cells o

Updated on: May 08,2024

A new pathway to 'reprogram' killer cells

by University of BernNK cells (brown) patrolling between cells of a healthy human lymph node. Credit: Institute of Pathology, University of BernThe so-called natural killer (NK) cells are cells o

Updated on:May 08,2024

Spike proteins of SARS-CoV-2 relatives can evolve against immune responses

by eLifeNovel Coronavirus SARS-CoV-2 Transmission electron micrograph of SARS-CoV-2 virus particles, isolated from a patient. Image captured and color-enhanced at the NIAID Integrated Research Fa

Updated on: April 22,2024

Spike proteins of SARS-CoV-2 relatives can evolve against immune responses

by eLifeNovel Coronavirus SARS-CoV-2 Transmission electron micrograph of SARS-CoV-2 virus particles, isolated from a patient. Image captured and color-enhanced at the NIAID Integrated Research Fa

Updated on:April 22,2024

How a virus that infects 50% of people is helping develop new cancer treatments

by Rebecca Aicheler,The ConversationCredit: AI-generated imageMost of us have heard of viruses such asmeaslesandmumps—not to mention the more seriousHIVandEbo

Updated on: May 07,2024

How a virus that infects 50% of people is helping develop new cancer treatments

by Rebecca Aicheler,The ConversationCredit: AI-generated imageMost of us have heard of viruses such asmeaslesandmumps—not to mention the more seriousHIVandEbo

Updated on:May 07,2024

Early combined treatment with biologic and conventional DMARDs could be effective for polyarticular juvenile arthritis

by American College of RheumatologyCredit: CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that patients sta

Updated on: March 28,2024

Early combined treatment with biologic and conventional DMARDs could be effective for polyarticular juvenile arthritis

by American College of RheumatologyCredit: CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that patients sta

Updated on:March 28,2024

Smoking impairs treatment response in inflammatory back arthritis

by British Medical JournalSmoking harms nearly every organ in the body and causes many diseases. Credit: CDC/Debora CartagenaSmoking impairs the response to biological drugs used to treat inflamm

Updated on: May 13,2024

Smoking impairs treatment response in inflammatory back arthritis

by British Medical JournalSmoking harms nearly every organ in the body and causes many diseases. Credit: CDC/Debora CartagenaSmoking impairs the response to biological drugs used to treat inflamm

Updated on:May 13,2024

A common skin bacterium put children with severe eczema at higher risk of food allergy

by King's College LondonCredit: CC0 Public DomainIn a new study published today in theJournal of Allergy and Clinical Immunology, scientists from King's College London have found th

Updated on: May 08,2024

A common skin bacterium put children with severe eczema at higher risk of food allergy

by King's College LondonCredit: CC0 Public DomainIn a new study published today in theJournal of Allergy and Clinical Immunology, scientists from King's College London have found th

Updated on:May 08,2024