Tracking down the genetic causes of lupus to personalize treatment

by University of California - BerkeleyMany autoimmune diseases, including lupus, have been linked to problems with the toll-like receptors (TLR) on immune cells, in particular the TLR7 and TLR8 r

Updated on: May 30,2024

Tracking down the genetic causes of lupus to personalize treatment

by University of California - BerkeleyMany autoimmune diseases, including lupus, have been linked to problems with the toll-like receptors (TLR) on immune cells, in particular the TLR7 and TLR8 r

Updated on:May 30,2024

How one inflammatory disorder exacerbates another

by Katherine Unger Baillie,University of PennsylvaniaInflammation in the gums can increase susceptibility to other forms of inflammation, such as arthritis, through changes to immune cell precur

Updated on: March 25,2024

How one inflammatory disorder exacerbates another

by Katherine Unger Baillie,University of PennsylvaniaInflammation in the gums can increase susceptibility to other forms of inflammation, such as arthritis, through changes to immune cell precur

Updated on:March 25,2024

Immune system's moonlighters point the way to a new therapeutic target

FEBRUARY 20, 2024byCold Spring Harbor LaboratoryGraphical abstract. Credit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.01.007Our immune system is remarkably powerful. It quickly

Updated on: March 25,2024

Immune system's moonlighters point the way to a new therapeutic target

FEBRUARY 20, 2024byCold Spring Harbor LaboratoryGraphical abstract. Credit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.01.007Our immune system is remarkably powerful. It quickly

Updated on:March 25,2024

Current asthma at age 7 linked to chronic rhinosinusitis in middle age

by Elana GotkineCredit: Pixabay/CC0 Public DomainCurrent asthma, head colds, and tonsillitis at age 7 years are associated with chronic rhinosinusitis (CRS) at midlife, according to a studypubli

Updated on: July 17,2024

Current asthma at age 7 linked to chronic rhinosinusitis in middle age

by Elana GotkineCredit: Pixabay/CC0 Public DomainCurrent asthma, head colds, and tonsillitis at age 7 years are associated with chronic rhinosinusitis (CRS) at midlife, according to a studypubli

Updated on:July 17,2024

Three-dimensional label-free morphology of CD8+ T cells as a sepsis biomarker

by Chinese Academy of Sciencesa, Schematic overview of the study workflow. Blood was sampled three times in the sepsis recovery cohort and once in the healthy control cohort. CD8+ T cells were ex

Updated on: April 09,2024

Three-dimensional label-free morphology of CD8+ T cells as a sepsis biomarker

by Chinese Academy of Sciencesa, Schematic overview of the study workflow. Blood was sampled three times in the sepsis recovery cohort and once in the healthy control cohort. CD8+ T cells were ex

Updated on:April 09,2024

An unconventional ion channel

by Ludwig Maximilian University of MunichTRPML2 channels (green) on vacuolin-enlarged fast recycling vesicles (positive for the fast-recycling marker RAB4A (red)), permitting to microdissect thes

Updated on: April 24,2024

An unconventional ion channel

by Ludwig Maximilian University of MunichTRPML2 channels (green) on vacuolin-enlarged fast recycling vesicles (positive for the fast-recycling marker RAB4A (red)), permitting to microdissect thes

Updated on:April 24,2024

Man vaccinated for COVID 217 times reports no side effects: scientists

Credit: Maksim Goncharenok from PexelsA German man who deliberately got vaccinated for COVID-19 a whopping 217 times did not report any side effects from his many jabs, according to researchers studyi

Updated on: March 19,2024

Man vaccinated for COVID 217 times reports no side effects: scientists

Credit: Maksim Goncharenok from PexelsA German man who deliberately got vaccinated for COVID-19 a whopping 217 times did not report any side effects from his many jabs, according to researchers studyi

Updated on:March 19,2024

CAR-T cell therapy leads to long-term remission in lupus while maintaining vaccine response

by American College of RheumatologyCredit: CC0 Public DomainNew researchatACR Convergence 2023, the American College of Rheumatology's annual meeting, demonstrates that CAR-T cell

Updated on: April 09,2024

CAR-T cell therapy leads to long-term remission in lupus while maintaining vaccine response

by American College of RheumatologyCredit: CC0 Public DomainNew researchatACR Convergence 2023, the American College of Rheumatology's annual meeting, demonstrates that CAR-T cell

Updated on:April 09,2024

Combined inhibition of TNF-alpha, IL-17 effective in RA model

(HealthDay)—Combined inhibition of tumor necrosis factor (TNF) α and interleukin (IL)-17 is more effective than single blockade in cultures of human fibroblast-like synoviocytes (FLS), according to an

Updated on: April 08,2024

Combined inhibition of TNF-alpha, IL-17 effective in RA model

(HealthDay)—Combined inhibition of tumor necrosis factor (TNF) α and interleukin (IL)-17 is more effective than single blockade in cultures of human fibroblast-like synoviocytes (FLS), according to an

Updated on:April 08,2024

Eyes serve as immunological barrier in fight against brain pathogens, finds study

by Yale University10x VISIUM Spatial sequencing of the mouse globe and optic nerve. Mouse eyes were processed using traditional FFPE-based histology preparation. Samples were processed using the

Updated on: March 07,2024

Eyes serve as immunological barrier in fight against brain pathogens, finds study

by Yale University10x VISIUM Spatial sequencing of the mouse globe and optic nerve. Mouse eyes were processed using traditional FFPE-based histology preparation. Samples were processed using the

Updated on:March 07,2024

CABYR-a/b and CABYR-c hold promise as targets for specific immunotherapy

by Impact Journals LLC(A) Immunohistochemistry (IHC) staining of testis (positive control). (B) IHC staining of colonic adenocarcinoma. (C) IHC stating of Normal colonic mucosa (negative control). Pur

Updated on: April 08,2024

CABYR-a/b and CABYR-c hold promise as targets for specific immunotherapy

by Impact Journals LLC(A) Immunohistochemistry (IHC) staining of testis (positive control). (B) IHC staining of colonic adenocarcinoma. (C) IHC stating of Normal colonic mucosa (negative control). Pur

Updated on:April 08,2024

Adults with lupus, common types of arthritis have similar risks of getting admitted to hospital as other COVID patients

by NYU Langone HealthCredit: Unsplash/CC0 Public DomainMost adults with systemic lupus erythematosus (SLE) are not at increased risk of hospitalization from COVID-19 due to medications used to da

Updated on: June 06,2024

Adults with lupus, common types of arthritis have similar risks of getting admitted to hospital as other COVID patients

by NYU Langone HealthCredit: Unsplash/CC0 Public DomainMost adults with systemic lupus erythematosus (SLE) are not at increased risk of hospitalization from COVID-19 due to medications used to da

Updated on:June 06,2024