Immune system's moonlighters point the way to a new therapeutic target

FEBRUARY 20, 2024byCold Spring Harbor LaboratoryGraphical abstract. Credit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.01.007Our immune system is remarkably powerful. It quickly

Updated on: March 25,2024

Immune system's moonlighters point the way to a new therapeutic target

FEBRUARY 20, 2024byCold Spring Harbor LaboratoryGraphical abstract. Credit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.01.007Our immune system is remarkably powerful. It quickly

Updated on:March 25,2024

Frailty may be reversible for some people with rheumatoid arthritis

by University of GlasgowCredit: Unsplash/CC0 Public DomainRheumatoid arthritis patients living with frailty may find their frailty is reversible following treatment, according to a new study.The

Updated on: June 26,2024

Frailty may be reversible for some people with rheumatoid arthritis

by University of GlasgowCredit: Unsplash/CC0 Public DomainRheumatoid arthritis patients living with frailty may find their frailty is reversible following treatment, according to a new study.The

Updated on:June 26,2024

Study of T cells from COVID-19 convalescents guides vaccine strategies

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of the SARS-CoV-2-specific immune response kinetics. Memory T cells are maintained after recovery from COVID-19 with the

Updated on: April 10,2024

Study of T cells from COVID-19 convalescents guides vaccine strategies

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of the SARS-CoV-2-specific immune response kinetics. Memory T cells are maintained after recovery from COVID-19 with the

Updated on:April 10,2024

COVID-19's deadliness for men reveals why researchers should have been studying immune system sex differences years ago

by Adam Moeser,The ConversationCredit: CC0 Public DomainWhen it comes to surviving critical cases of COVID-19, it appears that men draw the short straw.Initial reports from China revealed the ea

Updated on: April 10,2024

COVID-19's deadliness for men reveals why researchers should have been studying immune system sex differences years ago

by Adam Moeser,The ConversationCredit: CC0 Public DomainWhen it comes to surviving critical cases of COVID-19, it appears that men draw the short straw.Initial reports from China revealed the ea

Updated on:April 10,2024

Running, even in excess, doesn't lead to more osteoarthritis and hip replacements

by Dan Krotz,Lawrence Berkeley National LaboratoryCredit: Berkeley Lab photographer Roy Kaltschmidt(Medical Xpress)—Need another reason to dust off those running shoes in the back of the closet?

Updated on: June 06,2024

Running, even in excess, doesn't lead to more osteoarthritis and hip replacements

by Dan Krotz,Lawrence Berkeley National LaboratoryCredit: Berkeley Lab photographer Roy Kaltschmidt(Medical Xpress)—Need another reason to dust off those running shoes in the back of the closet?

Updated on:June 06,2024

A turncoat protein allows viruses to ride roughshod in the liver, paving the way to cancer

by Delthia Ricks , Medical XpressImages showing the distribution of tagged STING and HA-HPN proteins in liver cells. Credit: F. Hsin et al.,Science Signaling(2021)Chronic viral infections

Updated on: April 24,2024

A turncoat protein allows viruses to ride roughshod in the liver, paving the way to cancer

by Delthia Ricks , Medical XpressImages showing the distribution of tagged STING and HA-HPN proteins in liver cells. Credit: F. Hsin et al.,Science Signaling(2021)Chronic viral infections

Updated on:April 24,2024

How chronic knee osteoarthritis pain affects cognitive function

by University of NottinghamCredit: CC0 Public DomainNew research suggests that chronic knee pain caused by osteoarthritis does not cause cognitive impairment in isolation, indicating that other f

Updated on: May 23,2024

How chronic knee osteoarthritis pain affects cognitive function

by University of NottinghamCredit: CC0 Public DomainNew research suggests that chronic knee pain caused by osteoarthritis does not cause cognitive impairment in isolation, indicating that other f

Updated on:May 23,2024

Common sites of bone erosion in rheumatoid arthritis

(HealthDay)—Joint recesses with bone erosion are more likely to exhibit greater severity of joint inflammation on ultrasound (US) examination, according to a study published online Oct. 25 in the&nbsp

Updated on: May 08,2024

Common sites of bone erosion in rheumatoid arthritis

(HealthDay)—Joint recesses with bone erosion are more likely to exhibit greater severity of joint inflammation on ultrasound (US) examination, according to a study published online Oct. 25 in the&nbsp

Updated on:May 08,2024

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on: January 11,2025

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on:January 11,2025

The novel mechanisms for inflammation and cancer induced by HTLV-1

by Kumamoto UniversityCredit: Unsplash/CC0 Public DomainA research group from Kumamoto University, Japan, has clarified the mechanism by which human T-cell leukemia virus type 1 (HTLV-1) causes i

Updated on: April 16,2024

The novel mechanisms for inflammation and cancer induced by HTLV-1

by Kumamoto UniversityCredit: Unsplash/CC0 Public DomainA research group from Kumamoto University, Japan, has clarified the mechanism by which human T-cell leukemia virus type 1 (HTLV-1) causes i

Updated on:April 16,2024

TET proteins regulate factors essential for normal antibody production

by La Jolla Institute for ImmunologyMutant B cells lacking TET2 and TET3 produce an overabundance of a class of antibody called IgM, whereas normal control B cells churned out more effective antibodie

Updated on: April 24,2024

TET proteins regulate factors essential for normal antibody production

by La Jolla Institute for ImmunologyMutant B cells lacking TET2 and TET3 produce an overabundance of a class of antibody called IgM, whereas normal control B cells churned out more effective antibodie

Updated on:April 24,2024

Physical activity and sleep in adults with arthritis

by WileyA new study published in Arthritis Care & Research has examined patterns of 24-hour physical activity and sleep among patients with rheumatoid arthritis, lupus, and knee osteoarthriti

Updated on: May 08,2024

Physical activity and sleep in adults with arthritis

by WileyA new study published in Arthritis Care & Research has examined patterns of 24-hour physical activity and sleep among patients with rheumatoid arthritis, lupus, and knee osteoarthriti

Updated on:May 08,2024