TET proteins regulate factors essential for normal antibody production

by La Jolla Institute for ImmunologyMutant B cells lacking TET2 and TET3 produce an overabundance of a class of antibody called IgM, whereas normal control B cells churned out more effective antibodie

Updated on: April 24,2024

TET proteins regulate factors essential for normal antibody production

by La Jolla Institute for ImmunologyMutant B cells lacking TET2 and TET3 produce an overabundance of a class of antibody called IgM, whereas normal control B cells churned out more effective antibodie

Updated on:April 24,2024

Can losing weight combat the structural defects of knee osteoarthritis?

by WileyCredit: CC0 Public DomainIn a study published inArthritis & Rheumatology, a decrease in body mass index (BMI) was associated with both a lower incidence of the structural defect

Updated on: May 19,2024

Can losing weight combat the structural defects of knee osteoarthritis?

by WileyCredit: CC0 Public DomainIn a study published inArthritis & Rheumatology, a decrease in body mass index (BMI) was associated with both a lower incidence of the structural defect

Updated on:May 19,2024

A turncoat protein allows viruses to ride roughshod in the liver, paving the way to cancer

by Delthia Ricks , Medical XpressImages showing the distribution of tagged STING and HA-HPN proteins in liver cells. Credit: F. Hsin et al.,Science Signaling(2021)Chronic viral infections

Updated on: April 24,2024

A turncoat protein allows viruses to ride roughshod in the liver, paving the way to cancer

by Delthia Ricks , Medical XpressImages showing the distribution of tagged STING and HA-HPN proteins in liver cells. Credit: F. Hsin et al.,Science Signaling(2021)Chronic viral infections

Updated on:April 24,2024

Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on: March 07,2024

Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on:March 07,2024

COVID-19 science: Understanding the basics of 'herd immunity'

by Dr. Eduardo Sanchez,American Heart AssociationCredit: CC0 Public DomainRecently I heard a medical "expert" on the news incorrectly define the term "herd immunity." It'

Updated on: April 10,2024

COVID-19 science: Understanding the basics of 'herd immunity'

by Dr. Eduardo Sanchez,American Heart AssociationCredit: CC0 Public DomainRecently I heard a medical "expert" on the news incorrectly define the term "herd immunity." It'

Updated on:April 10,2024

With or without allergies, outcomes similar for hospitalized patients with COVID-19

byAmerican College of Allergy, Asthma, and ImmunologyDuring the COVID-19 pandemic, attention has been focused on how those with both allergies and asthma might be affected should they become ill

Updated on: March 05,2024

With or without allergies, outcomes similar for hospitalized patients with COVID-19

byAmerican College of Allergy, Asthma, and ImmunologyDuring the COVID-19 pandemic, attention has been focused on how those with both allergies and asthma might be affected should they become ill

Updated on:March 05,2024

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on: January 11,2025

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on:January 11,2025

Specially designed footwear reduces pain of knee osteoarthritis

by Boston University School of MedicineCredit: CC0 Public DomainWearing shoes specifically designed with a novel sole (biomechanical footwear) significantly reduces the pain associated with knee

Updated on: April 20,2024

Specially designed footwear reduces pain of knee osteoarthritis

by Boston University School of MedicineCredit: CC0 Public DomainWearing shoes specifically designed with a novel sole (biomechanical footwear) significantly reduces the pain associated with knee

Updated on:April 20,2024

CABYR-a/b and CABYR-c hold promise as targets for specific immunotherapy

by Impact Journals LLC(A) Immunohistochemistry (IHC) staining of testis (positive control). (B) IHC staining of colonic adenocarcinoma. (C) IHC stating of Normal colonic mucosa (negative control). Pur

Updated on: April 08,2024

CABYR-a/b and CABYR-c hold promise as targets for specific immunotherapy

by Impact Journals LLC(A) Immunohistochemistry (IHC) staining of testis (positive control). (B) IHC staining of colonic adenocarcinoma. (C) IHC stating of Normal colonic mucosa (negative control). Pur

Updated on:April 08,2024

Surprise rheumatoid arthritis discovery points to new treatment for joint inflammation

by University of VirginiaCredit: Alexandra Angelich, University CommunicationsResearchers at the University of Virginia School of Medicine have identified an unexpected contributor to rheumatoid

Updated on: June 17,2024

Surprise rheumatoid arthritis discovery points to new treatment for joint inflammation

by University of VirginiaCredit: Alexandra Angelich, University CommunicationsResearchers at the University of Virginia School of Medicine have identified an unexpected contributor to rheumatoid

Updated on:June 17,2024

Man vaccinated for COVID 217 times reports no side effects: scientists

Credit: Maksim Goncharenok from PexelsA German man who deliberately got vaccinated for COVID-19 a whopping 217 times did not report any side effects from his many jabs, according to researchers studyi

Updated on: March 19,2024

Man vaccinated for COVID 217 times reports no side effects: scientists

Credit: Maksim Goncharenok from PexelsA German man who deliberately got vaccinated for COVID-19 a whopping 217 times did not report any side effects from his many jabs, according to researchers studyi

Updated on:March 19,2024

Post-COVID-19 conditions alter a person's immune response

by Cedars-Sinai Medical CenterCredit: Unsplash/CC0 Public DomainA new study by investigators from the Smidt Heart Institute at Cedars-Sinai suggests long COVID-19 might be caused by a dysfunction

Updated on: April 09,2024

Post-COVID-19 conditions alter a person's immune response

by Cedars-Sinai Medical CenterCredit: Unsplash/CC0 Public DomainA new study by investigators from the Smidt Heart Institute at Cedars-Sinai suggests long COVID-19 might be caused by a dysfunction

Updated on:April 09,2024