New insights on B cells: Researchers explore building better antibodies and curbing autoimmune diseases

by Nancy Fliesler,Harvard Medical SchoolGb3 drives affinity and diversity of antibody responses and protects against viral infection. Credit:Science(2024). DOI: 10.1126/science.adg05

Updated on: April 28,2024

New insights on B cells: Researchers explore building better antibodies and curbing autoimmune diseases

by Nancy Fliesler,Harvard Medical SchoolGb3 drives affinity and diversity of antibody responses and protects against viral infection. Credit:Science(2024). DOI: 10.1126/science.adg05

Updated on:April 28,2024

An unconventional ion channel

by Ludwig Maximilian University of MunichTRPML2 channels (green) on vacuolin-enlarged fast recycling vesicles (positive for the fast-recycling marker RAB4A (red)), permitting to microdissect thes

Updated on: April 24,2024

An unconventional ion channel

by Ludwig Maximilian University of MunichTRPML2 channels (green) on vacuolin-enlarged fast recycling vesicles (positive for the fast-recycling marker RAB4A (red)), permitting to microdissect thes

Updated on:April 24,2024

Does COVID-19 vaccination affect rheumatic and musculoskeletal disease flares?

by WileyCredit: CC0 Public DomainIn a study of 1,377 patients with rheumatic and musculoskeletal diseases—such as inflammatory arthritis and lupus—flares of their conditions were uncommon followi

Updated on: June 26,2024

Does COVID-19 vaccination affect rheumatic and musculoskeletal disease flares?

by WileyCredit: CC0 Public DomainIn a study of 1,377 patients with rheumatic and musculoskeletal diseases—such as inflammatory arthritis and lupus—flares of their conditions were uncommon followi

Updated on:June 26,2024

Eyes serve as immunological barrier in fight against brain pathogens, finds study

by Yale University10x VISIUM Spatial sequencing of the mouse globe and optic nerve. Mouse eyes were processed using traditional FFPE-based histology preparation. Samples were processed using the

Updated on: March 07,2024

Eyes serve as immunological barrier in fight against brain pathogens, finds study

by Yale University10x VISIUM Spatial sequencing of the mouse globe and optic nerve. Mouse eyes were processed using traditional FFPE-based histology preparation. Samples were processed using the

Updated on:March 07,2024

Smoking impairs treatment response in inflammatory back arthritis

by British Medical JournalSmoking harms nearly every organ in the body and causes many diseases. Credit: CDC/Debora CartagenaSmoking impairs the response to biological drugs used to treat inflamm

Updated on: May 13,2024

Smoking impairs treatment response in inflammatory back arthritis

by British Medical JournalSmoking harms nearly every organ in the body and causes many diseases. Credit: CDC/Debora CartagenaSmoking impairs the response to biological drugs used to treat inflamm

Updated on:May 13,2024

Man vaccinated for COVID 217 times reports no side effects: scientists

Credit: Maksim Goncharenok from PexelsA German man who deliberately got vaccinated for COVID-19 a whopping 217 times did not report any side effects from his many jabs, according to researchers studyi

Updated on: March 19,2024

Man vaccinated for COVID 217 times reports no side effects: scientists

Credit: Maksim Goncharenok from PexelsA German man who deliberately got vaccinated for COVID-19 a whopping 217 times did not report any side effects from his many jabs, according to researchers studyi

Updated on:March 19,2024

Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on: March 07,2024

Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on:March 07,2024

SARS-CoV-2 curtails immune response in the gut

by European Molecular Biology LaboratoryThe researchers were able to monitor the virus's growth in organoids derived from human intestinal cells. Pink and red show areas of SARS-CoV-2 infecti

Updated on: April 22,2024

SARS-CoV-2 curtails immune response in the gut

by European Molecular Biology LaboratoryThe researchers were able to monitor the virus's growth in organoids derived from human intestinal cells. Pink and red show areas of SARS-CoV-2 infecti

Updated on:April 22,2024

COVID-19: Not all antibodies are equal in fighting the virus

by University of MontrealA colorized scanning electron micrograph of the SARS-CoV-2 virus. Credit: NIAIDWhen a person is infected by SARS-CoV-2, the number of antibodies able to neutralize the vi

Updated on: April 10,2024

COVID-19: Not all antibodies are equal in fighting the virus

by University of MontrealA colorized scanning electron micrograph of the SARS-CoV-2 virus. Credit: NIAIDWhen a person is infected by SARS-CoV-2, the number of antibodies able to neutralize the vi

Updated on:April 10,2024

Trial compares therapies for reducing cardiovascular risk among people with rheumatoid arthritis

by Brigham and Women's HospitalCredit: Unsplash/CC0 Public DomainPeople with rheumatoid arthritis are at increased risk of cardiovascular (CV) disease, with studies indicating an approximate

Updated on: May 13,2024

Trial compares therapies for reducing cardiovascular risk among people with rheumatoid arthritis

by Brigham and Women's HospitalCredit: Unsplash/CC0 Public DomainPeople with rheumatoid arthritis are at increased risk of cardiovascular (CV) disease, with studies indicating an approximate

Updated on:May 13,2024

CAR T cell therapies may lead to reactivation of childhood viral infections

by Justin Jackson , Medical XpressPetabase-scale analysis of viral nucleic acids reveals that HHV-6 is reactivated in human T cells. a, Schematic of life cycles of endogenous human viruses. Viruses ca

Updated on: April 09,2024

CAR T cell therapies may lead to reactivation of childhood viral infections

by Justin Jackson , Medical XpressPetabase-scale analysis of viral nucleic acids reveals that HHV-6 is reactivated in human T cells. a, Schematic of life cycles of endogenous human viruses. Viruses ca

Updated on:April 09,2024

SARS-CoV-2 variant B.1.617 attacks immune system

by The German Primate CenterThe spike protein on the surface of SARS-CoV-2 virions mediates entry into target cells. It Is the main target for neutralizing antibodies that are produced following

Updated on: April 22,2024

SARS-CoV-2 variant B.1.617 attacks immune system

by The German Primate CenterThe spike protein on the surface of SARS-CoV-2 virions mediates entry into target cells. It Is the main target for neutralizing antibodies that are produced following

Updated on:April 22,2024