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Immunology & Rheumatology
Focuses on rheumatic and immune diseases.
Sub Categories on Immunology & Rheumatology
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A novel animal model for analysing human natural killer cell functions in vivo

A novel animal model for analysing human natural killer cell functions in vivo

by Kawasaki CityFigure 1: Humanized mice were generated by transplanting 2.5 x 104 human cord blood-derived CD34+ HSC cells into irradiated NOG-IL-2 mice. After human CD34+ cell transplantation, human

A novel animal model for analysing human natural killer cell functions in vivo

by Kawasaki CityFigure 1: Humanized mice were generated by transplanting 2.5 x 104 human cord blood-derived CD34+ HSC cells into irradiated NOG-IL-2 mice. After human CD34+ cell transplantation, human
Analysis of DNA reveals weapons used by our immune cells to fight tuberculosis

Analysis of DNA reveals weapons used by our immune cells to fight tuberculosis

by Agency for Science, Technology and Research (A*STAR), SingaporeFig. 1: Histone acetylome-wide association study of TB. Credit: DOI: 10.1038/s41564-021-01049-wA study led by the Agency for Scie

Analysis of DNA reveals weapons used by our immune cells to fight tuberculosis

by Agency for Science, Technology and Research (A*STAR), SingaporeFig. 1: Histone acetylome-wide association study of TB. Credit: DOI: 10.1038/s41564-021-01049-wA study led by the Agency for Scie
T cells take the lead in controlling SARS-CoV-2 and reducing COVID-19 disease severity

T cells take the lead in controlling SARS-CoV-2 and reducing COVID-19 disease severity

by La Jolla Institute for ImmunologyA multi-layered, virus-specific immune response is important for controlling the virus during the acute phase of the infection and reducing COVID-19 disease se

T cells take the lead in controlling SARS-CoV-2 and reducing COVID-19 disease severity

by La Jolla Institute for ImmunologyA multi-layered, virus-specific immune response is important for controlling the virus during the acute phase of the infection and reducing COVID-19 disease se
Five genes tied to osteoarthritis progression

Five genes tied to osteoarthritis progression

(HealthDay)—Five genes may serve as biomarkers for osteoarthritis (OA) progression, according to a study published online Feb. 2 in theInternational Journal of Rheumatic Diseases.Beiyue Wang, fr

Five genes tied to osteoarthritis progression

(HealthDay)—Five genes may serve as biomarkers for osteoarthritis (OA) progression, according to a study published online Feb. 2 in theInternational Journal of Rheumatic Diseases.Beiyue Wang, fr
A safer treatment path for high-risk children to overcome food allergies

A safer treatment path for high-risk children to overcome food allergies

by University of British ColumbiaCredit: Unsplash/CC0 Public DomainNew research from the University of British Columbia reveals a safe path to overcoming food allergies for older children and oth

A safer treatment path for high-risk children to overcome food allergies

by University of British ColumbiaCredit: Unsplash/CC0 Public DomainNew research from the University of British Columbia reveals a safe path to overcoming food allergies for older children and oth
m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati
Findings give hope to plant extract as possible lupus treatment

Findings give hope to plant extract as possible lupus treatment

by University of HoustonNew findings by UH biomedical engineer Chandra Mohan and his team raise hope for a new class of drugs to treat lupus that may not include the long list of adverse risks an

Findings give hope to plant extract as possible lupus treatment

by University of HoustonNew findings by UH biomedical engineer Chandra Mohan and his team raise hope for a new class of drugs to treat lupus that may not include the long list of adverse risks an
COVID-19, MIS-C and Kawasaki disease share same immune response

COVID-19, MIS-C and Kawasaki disease share same immune response

by University of California - San DiegoUC San Diego researchers summarize the similarities and differences between COVID-19, MIS-C and Kawasaki disease, three conditions unified by the same immun

COVID-19, MIS-C and Kawasaki disease share same immune response

by University of California - San DiegoUC San Diego researchers summarize the similarities and differences between COVID-19, MIS-C and Kawasaki disease, three conditions unified by the same immun
Scientists discover possible target for treating and preventing osteoarthritis

Scientists discover possible target for treating and preventing osteoarthritis

by University of FloridaCredit: CC0 Public DomainWear and tear on joints can lead to inflammation, breakdown of cartilage and development of osteoarthritis. Scientists at UF Scripps Biomedical Re

Scientists discover possible target for treating and preventing osteoarthritis

by University of FloridaCredit: CC0 Public DomainWear and tear on joints can lead to inflammation, breakdown of cartilage and development of osteoarthritis. Scientists at UF Scripps Biomedical Re
Nrf2: The custodian regulating oxidative stress and immunity against acrylamide toxicity

Nrf2: The custodian regulating oxidative stress and immunity against acrylamide toxicity

by Tokyo University of ScienceGenetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice. Credit: Tokyo University of ScienceAcrylamide is a toxic chemical compound that affect

Nrf2: The custodian regulating oxidative stress and immunity against acrylamide toxicity

by Tokyo University of ScienceGenetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice. Credit: Tokyo University of ScienceAcrylamide is a toxic chemical compound that affect
An existing drug may change tumor-associated macrophages back to cancer fighters

An existing drug may change tumor-associated macrophages back to cancer fighters

by Jeff Hansen,University of Alabama at BirminghamCredit: Unsplash/CC0 Public DomainA form of cell communication called hedgehog signaling is vital for embryonic development in mammals. Bu

An existing drug may change tumor-associated macrophages back to cancer fighters

by Jeff Hansen,University of Alabama at BirminghamCredit: Unsplash/CC0 Public DomainA form of cell communication called hedgehog signaling is vital for embryonic development in mammals. Bu
Key type of immune cell 'self-renews' in humans, new study finds

Key type of immune cell 'self-renews' in humans, new study finds

by Cardiff UniversityCredit: CC0 Public DomainA team of scientists has shown that a key type of immune cell "self-renews" in humans.It is an unexpected discovery, as it was previously t

Key type of immune cell 'self-renews' in humans, new study finds

by Cardiff UniversityCredit: CC0 Public DomainA team of scientists has shown that a key type of immune cell "self-renews" in humans.It is an unexpected discovery, as it was previously t