An existing drug may change tumor-associated macrophages back to cancer fighters

by Jeff Hansen,University of Alabama at BirminghamCredit: Unsplash/CC0 Public DomainA form of cell communication called hedgehog signaling is vital for embryonic development in mammals. Bu

Updated on: March 26,2024

An existing drug may change tumor-associated macrophages back to cancer fighters

by Jeff Hansen,University of Alabama at BirminghamCredit: Unsplash/CC0 Public DomainA form of cell communication called hedgehog signaling is vital for embryonic development in mammals. Bu

Updated on:March 26,2024

The anterior chamber of the eye as a servant to medical research

by Karolinska InstitutetCredit: B Henrique, PixabayTo mechanistically understand what happens in the living body under physiological and pathological conditions, requires a non-invasive high spat

Updated on: March 07,2024

The anterior chamber of the eye as a servant to medical research

by Karolinska InstitutetCredit: B Henrique, PixabayTo mechanistically understand what happens in the living body under physiological and pathological conditions, requires a non-invasive high spat

Updated on:March 07,2024

Review discusses metabolic reprogramming of T cells

by Cactus CommunicationsT cell immunotherapy can be optimized by understanding the metabolism of T cells. This review article summarizes the intricacies of effector and memory T cell metabolic reprogr

Updated on: March 07,2024

Review discusses metabolic reprogramming of T cells

by Cactus CommunicationsT cell immunotherapy can be optimized by understanding the metabolism of T cells. This review article summarizes the intricacies of effector and memory T cell metabolic reprogr

Updated on:March 07,2024

New juvenile idiopathic arthritis guideline emphasizes disease-modifying treatments

by American College of RheumatologyCredit: CC0 Public DomainThe American College of Rheumatology (ACR) will preview the 2021 Guideline for the Treatment of Juvenile Idiopathic Arthritis at ACR Co

Updated on: May 08,2024

New juvenile idiopathic arthritis guideline emphasizes disease-modifying treatments

by American College of RheumatologyCredit: CC0 Public DomainThe American College of Rheumatology (ACR) will preview the 2021 Guideline for the Treatment of Juvenile Idiopathic Arthritis at ACR Co

Updated on:May 08,2024

Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on: March 07,2024

Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on:March 07,2024

Possible new biomarker for better detection of numerous inflammatory diseases

by Kiel UniversityTryptophan concentrations in the blood were significantly reduced in 9 of 13 chronic inflammatory diseases examined. Credit: S. Klahn, Exzellenzcluster PMITryptophan is an essen

Updated on: March 30,2024

Possible new biomarker for better detection of numerous inflammatory diseases

by Kiel UniversityTryptophan concentrations in the blood were significantly reduced in 9 of 13 chronic inflammatory diseases examined. Credit: S. Klahn, Exzellenzcluster PMITryptophan is an essen

Updated on:March 30,2024

New device monitors levels of inflammation-associated C-reactive protein in real time

byPolish Academy of SciencesGraphical abstract. Credit:ACS Sensors(2024). DOI: 10.1021/acssensors.4c00249As inflammation is the body's natural immune response to disease or infec

Updated on: September 02,2024

New device monitors levels of inflammation-associated C-reactive protein in real time

byPolish Academy of SciencesGraphical abstract. Credit:ACS Sensors(2024). DOI: 10.1021/acssensors.4c00249As inflammation is the body's natural immune response to disease or infec

Updated on:September 02,2024

SARS-CoV-2 variant B.1.617 attacks immune system

by The German Primate CenterThe spike protein on the surface of SARS-CoV-2 virions mediates entry into target cells. It Is the main target for neutralizing antibodies that are produced following

Updated on: April 22,2024

SARS-CoV-2 variant B.1.617 attacks immune system

by The German Primate CenterThe spike protein on the surface of SARS-CoV-2 virions mediates entry into target cells. It Is the main target for neutralizing antibodies that are produced following

Updated on:April 22,2024

CAR-T cell therapy leads to long-term remission in lupus while maintaining vaccine response

by American College of RheumatologyCredit: CC0 Public DomainNew researchatACR Convergence 2023, the American College of Rheumatology's annual meeting, demonstrates that CAR-T cell

Updated on: April 09,2024

CAR-T cell therapy leads to long-term remission in lupus while maintaining vaccine response

by American College of RheumatologyCredit: CC0 Public DomainNew researchatACR Convergence 2023, the American College of Rheumatology's annual meeting, demonstrates that CAR-T cell

Updated on:April 09,2024

High-intensity strength training no added benefit for knee osteoarthritis

High-intensity strength training does not significantly improve knee pain with osteoarthritis compared with low-intensity strength training or a control condition, according to a study published in th

Updated on: May 29,2024

High-intensity strength training no added benefit for knee osteoarthritis

High-intensity strength training does not significantly improve knee pain with osteoarthritis compared with low-intensity strength training or a control condition, according to a study published in th

Updated on:May 29,2024

Scientists warn of a 'tsunami' of osteoarthritis cases by 2050

by European Cooperation in Science and Technology (COST)View of the knee joint; 3D reconstruction of articular structures based on magnetic resonance imaging (MRI) and segmentation: with permission fr

Updated on: March 27,2024

Scientists warn of a 'tsunami' of osteoarthritis cases by 2050

by European Cooperation in Science and Technology (COST)View of the knee joint; 3D reconstruction of articular structures based on magnetic resonance imaging (MRI) and segmentation: with permission fr

Updated on:March 27,2024

Boosting CAR-T cell therapies from under the skin

by Benjamin Boettner,Harvard UniversityT-cell enhancing scaffolds can be locally injected under the skin following CAR-T cell therapy, and allowcirculating CAR-T cells to infiltrate their 3-dime

Updated on: June 15,2024

Boosting CAR-T cell therapies from under the skin

by Benjamin Boettner,Harvard UniversityT-cell enhancing scaffolds can be locally injected under the skin following CAR-T cell therapy, and allowcirculating CAR-T cells to infiltrate their 3-dime

Updated on:June 15,2024