Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on: May 14,2024

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on:May 14,2024

Gender, high DAS28-P index predictive of pain in early RA

(HealthDay) -- For patients with rheumatoid arthritis (RA), female gender and having a high proportion of disease activity score (DAS28) attributable to patient-reported components (joint tenderness a

Updated on: April 08,2024

Gender, high DAS28-P index predictive of pain in early RA

(HealthDay) -- For patients with rheumatoid arthritis (RA), female gender and having a high proportion of disease activity score (DAS28) attributable to patient-reported components (joint tenderness a

Updated on:April 08,2024

Combined inhibition of TNF-alpha, IL-17 effective in RA model

(HealthDay)—Combined inhibition of tumor necrosis factor (TNF) α and interleukin (IL)-17 is more effective than single blockade in cultures of human fibroblast-like synoviocytes (FLS), according to an

Updated on: April 08,2024

Combined inhibition of TNF-alpha, IL-17 effective in RA model

(HealthDay)—Combined inhibition of tumor necrosis factor (TNF) α and interleukin (IL)-17 is more effective than single blockade in cultures of human fibroblast-like synoviocytes (FLS), according to an

Updated on:April 08,2024

Adults with lupus, common types of arthritis have similar risks of getting admitted to hospital as other COVID patients

by NYU Langone HealthCredit: Unsplash/CC0 Public DomainMost adults with systemic lupus erythematosus (SLE) are not at increased risk of hospitalization from COVID-19 due to medications used to da

Updated on: June 06,2024

Adults with lupus, common types of arthritis have similar risks of getting admitted to hospital as other COVID patients

by NYU Langone HealthCredit: Unsplash/CC0 Public DomainMost adults with systemic lupus erythematosus (SLE) are not at increased risk of hospitalization from COVID-19 due to medications used to da

Updated on:June 06,2024

Man vaccinated for COVID 217 times reports no side effects: scientists

Credit: Maksim Goncharenok from PexelsA German man who deliberately got vaccinated for COVID-19 a whopping 217 times did not report any side effects from his many jabs, according to researchers studyi

Updated on: March 19,2024

Man vaccinated for COVID 217 times reports no side effects: scientists

Credit: Maksim Goncharenok from PexelsA German man who deliberately got vaccinated for COVID-19 a whopping 217 times did not report any side effects from his many jabs, according to researchers studyi

Updated on:March 19,2024

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on: January 11,2025

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on:January 11,2025

Certain steps help lead to healthy pregnancies in women with rheumatoid arthritis

by WileyCredit: CC0 Public DomainFor women with rheumatoid arthritis (RA), taking certain steps to ensure that they have a healthy pregnancy leads to a reduced risk of complicated birth or miscar

Updated on: April 17,2024

Certain steps help lead to healthy pregnancies in women with rheumatoid arthritis

by WileyCredit: CC0 Public DomainFor women with rheumatoid arthritis (RA), taking certain steps to ensure that they have a healthy pregnancy leads to a reduced risk of complicated birth or miscar

Updated on:April 17,2024

Does COVID-19 vaccination affect rheumatic and musculoskeletal disease flares?

by WileyCredit: CC0 Public DomainIn a study of 1,377 patients with rheumatic and musculoskeletal diseases—such as inflammatory arthritis and lupus—flares of their conditions were uncommon followi

Updated on: June 26,2024

Does COVID-19 vaccination affect rheumatic and musculoskeletal disease flares?

by WileyCredit: CC0 Public DomainIn a study of 1,377 patients with rheumatic and musculoskeletal diseases—such as inflammatory arthritis and lupus—flares of their conditions were uncommon followi

Updated on:June 26,2024

Quality of cartilage repair tissue can also be determined without a surgery

by Medical University of ViennaA team at the MedUni Vienna, headed by Sebastian Apprich of the University Department of Radiodiagnostics at the High-Field Magnetic Resonance Centre of Excellence, has

Updated on: March 24,2024

Quality of cartilage repair tissue can also be determined without a surgery

by Medical University of ViennaA team at the MedUni Vienna, headed by Sebastian Apprich of the University Department of Radiodiagnostics at the High-Field Magnetic Resonance Centre of Excellence, has

Updated on:March 24,2024

How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on: March 27,2024

How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on:March 27,2024

Race plays a role in children's food allergies

by Nancy Difiore,Rush University Medical CenterCredit: Pixabay/CC0 Public DomainBlack children have significantly higher rates of shellfish and fish allergies than white children, confirming tha

Updated on: March 05,2024

Race plays a role in children's food allergies

by Nancy Difiore,Rush University Medical CenterCredit: Pixabay/CC0 Public DomainBlack children have significantly higher rates of shellfish and fish allergies than white children, confirming tha

Updated on:March 05,2024

Frailty may be reversible for some people with rheumatoid arthritis

by University of GlasgowCredit: Unsplash/CC0 Public DomainRheumatoid arthritis patients living with frailty may find their frailty is reversible following treatment, according to a new study.The

Updated on: June 26,2024

Frailty may be reversible for some people with rheumatoid arthritis

by University of GlasgowCredit: Unsplash/CC0 Public DomainRheumatoid arthritis patients living with frailty may find their frailty is reversible following treatment, according to a new study.The

Updated on:June 26,2024