Review discusses metabolic reprogramming of T cells

by Cactus CommunicationsT cell immunotherapy can be optimized by understanding the metabolism of T cells. This review article summarizes the intricacies of effector and memory T cell metabolic reprogr

Updated on: March 07,2024

Review discusses metabolic reprogramming of T cells

by Cactus CommunicationsT cell immunotherapy can be optimized by understanding the metabolism of T cells. This review article summarizes the intricacies of effector and memory T cell metabolic reprogr

Updated on:March 07,2024

SARS-CoV-2 variant B.1.617 attacks immune system

by The German Primate CenterThe spike protein on the surface of SARS-CoV-2 virions mediates entry into target cells. It Is the main target for neutralizing antibodies that are produced following

Updated on: April 22,2024

SARS-CoV-2 variant B.1.617 attacks immune system

by The German Primate CenterThe spike protein on the surface of SARS-CoV-2 virions mediates entry into target cells. It Is the main target for neutralizing antibodies that are produced following

Updated on:April 22,2024

Study compares hospitalized infection risk for biologics in RA

(HealthDay)—For patients with rheumatoid arthritis (RA) with prior biologic exposure, the risk of hospitalized infection is increased with etanercept, infliximab, and rituximab versus abatacept, accor

Updated on: April 08,2024

Study compares hospitalized infection risk for biologics in RA

(HealthDay)—For patients with rheumatoid arthritis (RA) with prior biologic exposure, the risk of hospitalized infection is increased with etanercept, infliximab, and rituximab versus abatacept, accor

Updated on:April 08,2024

Novel mechanism of ILC2 immune cell development may be involved in exacerbating allergic diseases

byChiba UniversityResearchers identify a G3SE-dependent mechanism of ILC2 development. Credit: Yosuke Toda and Arifumi Iwata from Chiba UniversityOverproduction of Group 2 innate lymphoid cells

Updated on: July 11,2024

Novel mechanism of ILC2 immune cell development may be involved in exacerbating allergic diseases

byChiba UniversityResearchers identify a G3SE-dependent mechanism of ILC2 development. Credit: Yosuke Toda and Arifumi Iwata from Chiba UniversityOverproduction of Group 2 innate lymphoid cells

Updated on:July 11,2024

Boosting CAR-T cell therapies from under the skin

by Benjamin Boettner,Harvard UniversityT-cell enhancing scaffolds can be locally injected under the skin following CAR-T cell therapy, and allowcirculating CAR-T cells to infiltrate their 3-dime

Updated on: June 15,2024

Boosting CAR-T cell therapies from under the skin

by Benjamin Boettner,Harvard UniversityT-cell enhancing scaffolds can be locally injected under the skin following CAR-T cell therapy, and allowcirculating CAR-T cells to infiltrate their 3-dime

Updated on:June 15,2024

Continuation vs. discontinuation of bDMARDs during the perioperative period

by Wolters Kluwer HealthCredit: Pixabay/CC0 Public DomainFor patients with rheumatic arthritis and other chronic inflammatory diseases, discontinuing biologic disease-modifying anti-rheumatic dru

Updated on: June 26,2024

Continuation vs. discontinuation of bDMARDs during the perioperative period

by Wolters Kluwer HealthCredit: Pixabay/CC0 Public DomainFor patients with rheumatic arthritis and other chronic inflammatory diseases, discontinuing biologic disease-modifying anti-rheumatic dru

Updated on:June 26,2024

Tracking down the genetic causes of lupus to personalize treatment

by University of California - BerkeleyMany autoimmune diseases, including lupus, have been linked to problems with the toll-like receptors (TLR) on immune cells, in particular the TLR7 and TLR8 r

Updated on: May 30,2024

Tracking down the genetic causes of lupus to personalize treatment

by University of California - BerkeleyMany autoimmune diseases, including lupus, have been linked to problems with the toll-like receptors (TLR) on immune cells, in particular the TLR7 and TLR8 r

Updated on:May 30,2024

Lymph node-like biomaterial scaffold for augmenting CAR-T cell therapy

byScience China PressOn the top, the schematic illustration shows the structure of scaffold, the seeding and proliferation of CAR-T cells within the scaffold after intratumor injection. On the b

Updated on: March 27,2024

Lymph node-like biomaterial scaffold for augmenting CAR-T cell therapy

byScience China PressOn the top, the schematic illustration shows the structure of scaffold, the seeding and proliferation of CAR-T cells within the scaffold after intratumor injection. On the b

Updated on:March 27,2024

The novel mechanisms for inflammation and cancer induced by HTLV-1

by Kumamoto UniversityCredit: Unsplash/CC0 Public DomainA research group from Kumamoto University, Japan, has clarified the mechanism by which human T-cell leukemia virus type 1 (HTLV-1) causes i

Updated on: April 16,2024

The novel mechanisms for inflammation and cancer induced by HTLV-1

by Kumamoto UniversityCredit: Unsplash/CC0 Public DomainA research group from Kumamoto University, Japan, has clarified the mechanism by which human T-cell leukemia virus type 1 (HTLV-1) causes i

Updated on:April 16,2024

How a virus that infects 50% of people is helping develop new cancer treatments

by Rebecca Aicheler,The ConversationCredit: AI-generated imageMost of us have heard of viruses such asmeaslesandmumps—not to mention the more seriousHIVandEbo

Updated on: May 07,2024

How a virus that infects 50% of people is helping develop new cancer treatments

by Rebecca Aicheler,The ConversationCredit: AI-generated imageMost of us have heard of viruses such asmeaslesandmumps—not to mention the more seriousHIVandEbo

Updated on:May 07,2024

Rheumatoid arthritis linked to peripheral artery disease

by Lori SolomonThere may be an association between rheumatoid arthritis (RA) and peripheral artery disease (PAD), according to a review published online Nov. 30 inRheumatology International.Tays

Updated on: June 26,2024

Rheumatoid arthritis linked to peripheral artery disease

by Lori SolomonThere may be an association between rheumatoid arthritis (RA) and peripheral artery disease (PAD), according to a review published online Nov. 30 inRheumatology International.Tays

Updated on:June 26,2024

Study offers insight into management of patients who have interstitial pneumonia with autoimmune features

by UT Southwestern Medical CenterCredit: Unsplash/CC0 Public DomainInterstitial pneumonia with autoimmune features (IPAF) is a disease with many possible causes and no standard of care, making it

Updated on: June 01,2024

Study offers insight into management of patients who have interstitial pneumonia with autoimmune features

by UT Southwestern Medical CenterCredit: Unsplash/CC0 Public DomainInterstitial pneumonia with autoimmune features (IPAF) is a disease with many possible causes and no standard of care, making it

Updated on:June 01,2024