Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on: March 07,2024

Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on:March 07,2024

Race plays a role in children's food allergies

by Nancy Difiore,Rush University Medical CenterCredit: Pixabay/CC0 Public DomainBlack children have significantly higher rates of shellfish and fish allergies than white children, confirming tha

Updated on: March 05,2024

Race plays a role in children's food allergies

by Nancy Difiore,Rush University Medical CenterCredit: Pixabay/CC0 Public DomainBlack children have significantly higher rates of shellfish and fish allergies than white children, confirming tha

Updated on:March 05,2024

Novel mechanism of ILC2 immune cell development may be involved in exacerbating allergic diseases

byChiba UniversityResearchers identify a G3SE-dependent mechanism of ILC2 development. Credit: Yosuke Toda and Arifumi Iwata from Chiba UniversityOverproduction of Group 2 innate lymphoid cells

Updated on: July 11,2024

Novel mechanism of ILC2 immune cell development may be involved in exacerbating allergic diseases

byChiba UniversityResearchers identify a G3SE-dependent mechanism of ILC2 development. Credit: Yosuke Toda and Arifumi Iwata from Chiba UniversityOverproduction of Group 2 innate lymphoid cells

Updated on:July 11,2024

Three-dimensional label-free morphology of CD8+ T cells as a sepsis biomarker

by Chinese Academy of Sciencesa, Schematic overview of the study workflow. Blood was sampled three times in the sepsis recovery cohort and once in the healthy control cohort. CD8+ T cells were ex

Updated on: April 09,2024

Three-dimensional label-free morphology of CD8+ T cells as a sepsis biomarker

by Chinese Academy of Sciencesa, Schematic overview of the study workflow. Blood was sampled three times in the sepsis recovery cohort and once in the healthy control cohort. CD8+ T cells were ex

Updated on:April 09,2024

Can losing weight combat the structural defects of knee osteoarthritis?

by WileyCredit: CC0 Public DomainIn a study published inArthritis & Rheumatology, a decrease in body mass index (BMI) was associated with both a lower incidence of the structural defect

Updated on: May 19,2024

Can losing weight combat the structural defects of knee osteoarthritis?

by WileyCredit: CC0 Public DomainIn a study published inArthritis & Rheumatology, a decrease in body mass index (BMI) was associated with both a lower incidence of the structural defect

Updated on:May 19,2024

Study offers insight into management of patients who have interstitial pneumonia with autoimmune features

by UT Southwestern Medical CenterCredit: Unsplash/CC0 Public DomainInterstitial pneumonia with autoimmune features (IPAF) is a disease with many possible causes and no standard of care, making it

Updated on: June 01,2024

Study offers insight into management of patients who have interstitial pneumonia with autoimmune features

by UT Southwestern Medical CenterCredit: Unsplash/CC0 Public DomainInterstitial pneumonia with autoimmune features (IPAF) is a disease with many possible causes and no standard of care, making it

Updated on:June 01,2024

Study compares hospitalized infection risk for biologics in RA

(HealthDay)—For patients with rheumatoid arthritis (RA) with prior biologic exposure, the risk of hospitalized infection is increased with etanercept, infliximab, and rituximab versus abatacept, accor

Updated on: April 08,2024

Study compares hospitalized infection risk for biologics in RA

(HealthDay)—For patients with rheumatoid arthritis (RA) with prior biologic exposure, the risk of hospitalized infection is increased with etanercept, infliximab, and rituximab versus abatacept, accor

Updated on:April 08,2024

SARS-CoV-2 curtails immune response in the gut

by European Molecular Biology LaboratoryThe researchers were able to monitor the virus's growth in organoids derived from human intestinal cells. Pink and red show areas of SARS-CoV-2 infecti

Updated on: April 22,2024

SARS-CoV-2 curtails immune response in the gut

by European Molecular Biology LaboratoryThe researchers were able to monitor the virus's growth in organoids derived from human intestinal cells. Pink and red show areas of SARS-CoV-2 infecti

Updated on:April 22,2024

The novel mechanisms for inflammation and cancer induced by HTLV-1

by Kumamoto UniversityCredit: Unsplash/CC0 Public DomainA research group from Kumamoto University, Japan, has clarified the mechanism by which human T-cell leukemia virus type 1 (HTLV-1) causes i

Updated on: April 16,2024

The novel mechanisms for inflammation and cancer induced by HTLV-1

by Kumamoto UniversityCredit: Unsplash/CC0 Public DomainA research group from Kumamoto University, Japan, has clarified the mechanism by which human T-cell leukemia virus type 1 (HTLV-1) causes i

Updated on:April 16,2024

New juvenile idiopathic arthritis guideline emphasizes disease-modifying treatments

by American College of RheumatologyCredit: CC0 Public DomainThe American College of Rheumatology (ACR) will preview the 2021 Guideline for the Treatment of Juvenile Idiopathic Arthritis at ACR Co

Updated on: May 08,2024

New juvenile idiopathic arthritis guideline emphasizes disease-modifying treatments

by American College of RheumatologyCredit: CC0 Public DomainThe American College of Rheumatology (ACR) will preview the 2021 Guideline for the Treatment of Juvenile Idiopathic Arthritis at ACR Co

Updated on:May 08,2024

With or without allergies, outcomes similar for hospitalized patients with COVID-19

byAmerican College of Allergy, Asthma, and ImmunologyDuring the COVID-19 pandemic, attention has been focused on how those with both allergies and asthma might be affected should they become ill

Updated on: March 05,2024

With or without allergies, outcomes similar for hospitalized patients with COVID-19

byAmerican College of Allergy, Asthma, and ImmunologyDuring the COVID-19 pandemic, attention has been focused on how those with both allergies and asthma might be affected should they become ill

Updated on:March 05,2024

How to keep kids with food allergies safe during Halloween

by Jason HowlandCredit: Unsplash/CC0 Public DomainHalloween can be a particularly difficult time for kids with food allergies since many common candies contain one or more common allergens. The conseq

Updated on: June 25,2024

How to keep kids with food allergies safe during Halloween

by Jason HowlandCredit: Unsplash/CC0 Public DomainHalloween can be a particularly difficult time for kids with food allergies since many common candies contain one or more common allergens. The conseq

Updated on:June 25,2024