New device for low-cost single-cell analysis identifies fibroblast subtypes in rheumatoid arthritis patients

by New York Genome CenterResearchers at the New York Genome Center (NYGC) and New York University (NYU) have taken steps to facilitate broad access to single-cell sequencing by developing a 3-D-printe

Updated on: April 07,2024

New device for low-cost single-cell analysis identifies fibroblast subtypes in rheumatoid arthritis patients

by New York Genome CenterResearchers at the New York Genome Center (NYGC) and New York University (NYU) have taken steps to facilitate broad access to single-cell sequencing by developing a 3-D-printe

Updated on:April 07,2024

CAR T cell therapies may lead to reactivation of childhood viral infections

by Justin Jackson , Medical XpressPetabase-scale analysis of viral nucleic acids reveals that HHV-6 is reactivated in human T cells. a, Schematic of life cycles of endogenous human viruses. Viruses ca

Updated on: April 09,2024

CAR T cell therapies may lead to reactivation of childhood viral infections

by Justin Jackson , Medical XpressPetabase-scale analysis of viral nucleic acids reveals that HHV-6 is reactivated in human T cells. a, Schematic of life cycles of endogenous human viruses. Viruses ca

Updated on:April 09,2024

Combined inhibition of TNF-alpha, IL-17 effective in RA model

(HealthDay)—Combined inhibition of tumor necrosis factor (TNF) α and interleukin (IL)-17 is more effective than single blockade in cultures of human fibroblast-like synoviocytes (FLS), according to an

Updated on: April 08,2024

Combined inhibition of TNF-alpha, IL-17 effective in RA model

(HealthDay)—Combined inhibition of tumor necrosis factor (TNF) α and interleukin (IL)-17 is more effective than single blockade in cultures of human fibroblast-like synoviocytes (FLS), according to an

Updated on:April 08,2024

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on: May 14,2024

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on:May 14,2024

Three-dimensional label-free morphology of CD8+ T cells as a sepsis biomarker

by Chinese Academy of Sciencesa, Schematic overview of the study workflow. Blood was sampled three times in the sepsis recovery cohort and once in the healthy control cohort. CD8+ T cells were ex

Updated on: April 09,2024

Three-dimensional label-free morphology of CD8+ T cells as a sepsis biomarker

by Chinese Academy of Sciencesa, Schematic overview of the study workflow. Blood was sampled three times in the sepsis recovery cohort and once in the healthy control cohort. CD8+ T cells were ex

Updated on:April 09,2024

SARS-CoV-2 curtails immune response in the gut

by European Molecular Biology LaboratoryThe researchers were able to monitor the virus's growth in organoids derived from human intestinal cells. Pink and red show areas of SARS-CoV-2 infecti

Updated on: April 22,2024

SARS-CoV-2 curtails immune response in the gut

by European Molecular Biology LaboratoryThe researchers were able to monitor the virus's growth in organoids derived from human intestinal cells. Pink and red show areas of SARS-CoV-2 infecti

Updated on:April 22,2024

With or without allergies, outcomes similar for hospitalized patients with COVID-19

byAmerican College of Allergy, Asthma, and ImmunologyDuring the COVID-19 pandemic, attention has been focused on how those with both allergies and asthma might be affected should they become ill

Updated on: March 05,2024

With or without allergies, outcomes similar for hospitalized patients with COVID-19

byAmerican College of Allergy, Asthma, and ImmunologyDuring the COVID-19 pandemic, attention has been focused on how those with both allergies and asthma might be affected should they become ill

Updated on:March 05,2024

The novel mechanisms for inflammation and cancer induced by HTLV-1

by Kumamoto UniversityCredit: Unsplash/CC0 Public DomainA research group from Kumamoto University, Japan, has clarified the mechanism by which human T-cell leukemia virus type 1 (HTLV-1) causes i

Updated on: April 16,2024

The novel mechanisms for inflammation and cancer induced by HTLV-1

by Kumamoto UniversityCredit: Unsplash/CC0 Public DomainA research group from Kumamoto University, Japan, has clarified the mechanism by which human T-cell leukemia virus type 1 (HTLV-1) causes i

Updated on:April 16,2024

How intravenous immunoglobulin antibodies resolve joint inflammation in rheumatoid arthritis

by Friedrich–Alexander University Erlangen–NurnbergGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.02.019Immunoglobulin G antibodies (IgB) play an important role

Updated on: June 17,2024

How intravenous immunoglobulin antibodies resolve joint inflammation in rheumatoid arthritis

by Friedrich–Alexander University Erlangen–NurnbergGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.02.019Immunoglobulin G antibodies (IgB) play an important role

Updated on:June 17,2024

Specially designed footwear reduces pain of knee osteoarthritis

by Boston University School of MedicineCredit: CC0 Public DomainWearing shoes specifically designed with a novel sole (biomechanical footwear) significantly reduces the pain associated with knee

Updated on: April 20,2024

Specially designed footwear reduces pain of knee osteoarthritis

by Boston University School of MedicineCredit: CC0 Public DomainWearing shoes specifically designed with a novel sole (biomechanical footwear) significantly reduces the pain associated with knee

Updated on:April 20,2024

β-damascone: Using the aroma component of rose fragrance as a novel immunomodulator

by Tokyo University of ScienceOveractivation of dendritic cells (DCs), components of the immune system, can cause immune diseases. β-damascone, a constituent of rose fragrance was identified as a

Updated on: May 07,2024

β-damascone: Using the aroma component of rose fragrance as a novel immunomodulator

by Tokyo University of ScienceOveractivation of dendritic cells (DCs), components of the immune system, can cause immune diseases. β-damascone, a constituent of rose fragrance was identified as a

Updated on:May 07,2024

Omega-3s could boost immunotherapy's cancer-fighting power

by Experimental BiologyOmega-3 supplementation improves the efficacy of immunotherapy in subcutaneous murine MB49 bladder cancer tumors. Credit: Abigail Kelly, Beth Israel Deaconess Medical Center/Har

Updated on: April 20,2024

Omega-3s could boost immunotherapy's cancer-fighting power

by Experimental BiologyOmega-3 supplementation improves the efficacy of immunotherapy in subcutaneous murine MB49 bladder cancer tumors. Credit: Abigail Kelly, Beth Israel Deaconess Medical Center/Har

Updated on:April 20,2024