Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on: March 07,2024

Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on:March 07,2024

How a virus that infects 50% of people is helping develop new cancer treatments

by Rebecca Aicheler,The ConversationCredit: AI-generated imageMost of us have heard of viruses such asmeaslesandmumps—not to mention the more seriousHIVandEbo

Updated on: May 07,2024

How a virus that infects 50% of people is helping develop new cancer treatments

by Rebecca Aicheler,The ConversationCredit: AI-generated imageMost of us have heard of viruses such asmeaslesandmumps—not to mention the more seriousHIVandEbo

Updated on:May 07,2024

Evolutionary study links subtle modifications in the morphology of the bipedal knee to osteoarthritis later in life

by Harvard UniversityA visual riff on the classic illustration, "March of Progress," highlighting the evolution of knee osteoarthritis. Credit: Tasha McAbee, Department of Orthopedics a

Updated on: May 08,2024

Evolutionary study links subtle modifications in the morphology of the bipedal knee to osteoarthritis later in life

by Harvard UniversityA visual riff on the classic illustration, "March of Progress," highlighting the evolution of knee osteoarthritis. Credit: Tasha McAbee, Department of Orthopedics a

Updated on:May 08,2024

Standardized treatment plans developed for new-onset JIA

Four standardized consensus treatment plans have been developed for patients with new-onset systemic juvenile idiopathic arthritis, according to research published in the July issue ofArthritis

Updated on: March 26,2024

Standardized treatment plans developed for new-onset JIA

Four standardized consensus treatment plans have been developed for patients with new-onset systemic juvenile idiopathic arthritis, according to research published in the July issue ofArthritis

Updated on:March 26,2024

Study investigates rates of adverse events for common rheumatoid arthritis drug

by Brigham and Women's HospitalCredit: CC0 Public DomainMethotrexate is a common drug with a long history; for the past 40 years, it's been used to treat a range of diseases. Today it is

Updated on: June 17,2024

Study investigates rates of adverse events for common rheumatoid arthritis drug

by Brigham and Women's HospitalCredit: CC0 Public DomainMethotrexate is a common drug with a long history; for the past 40 years, it's been used to treat a range of diseases. Today it is

Updated on:June 17,2024

New study examines potential factors related to the development of adult-onset food allergy

by American College of Allergy, Asthma, and ImmunologyCredit: Pixabay/CC0 Public DomainIt's estimated that 33 million Americans have food allergies (FAs), including 5.6 million children under

Updated on: April 24,2024

New study examines potential factors related to the development of adult-onset food allergy

by American College of Allergy, Asthma, and ImmunologyCredit: Pixabay/CC0 Public DomainIt's estimated that 33 million Americans have food allergies (FAs), including 5.6 million children under

Updated on:April 24,2024

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on: June 15,2024

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on:June 15,2024

New study points to a better way to ward off asthma triggers

by La Jolla Institute for ImmunologyLeft: Lung tissue of untreated mice. Right: Lung tissue of mice treated with antibodies blocking OX40L and CD30L. Credit: Dr. Gurupreet Sethi, La Jolla Institu

Updated on: May 05,2024

New study points to a better way to ward off asthma triggers

by La Jolla Institute for ImmunologyLeft: Lung tissue of untreated mice. Right: Lung tissue of mice treated with antibodies blocking OX40L and CD30L. Credit: Dr. Gurupreet Sethi, La Jolla Institu

Updated on:May 05,2024

Back pain link to 24-hour body clock revealed

by University of ManchesterCredit: University of ManchesterNew research by University of Manchester scientists has for the first time shown that our spinal discs have 24-hour body clocks which wh

Updated on: March 24,2024

Back pain link to 24-hour body clock revealed

by University of ManchesterCredit: University of ManchesterNew research by University of Manchester scientists has for the first time shown that our spinal discs have 24-hour body clocks which wh

Updated on:March 24,2024

Research into autoimmune liver condition suggests unique cell movements may drive disease

by University of BirminghamCD8+T cell internalization into BEC is a consistent event in PBC patients with ongoing disease. a) Representative fluorescence image of liver core biopsy, taken f

Updated on: March 07,2024

Research into autoimmune liver condition suggests unique cell movements may drive disease

by University of BirminghamCD8+T cell internalization into BEC is a consistent event in PBC patients with ongoing disease. a) Representative fluorescence image of liver core biopsy, taken f

Updated on:March 07,2024

New therapy shown to be effective in women with fibromyalgia and depression

by Universitat Oberta de CatalunyaCONSORT Diagram of participants flow in this randomized controlled trial. Credit:International Journal of Clinical and Health Psychology(2022). DOI: 10.10

Updated on: June 15,2024

New therapy shown to be effective in women with fibromyalgia and depression

by Universitat Oberta de CatalunyaCONSORT Diagram of participants flow in this randomized controlled trial. Credit:International Journal of Clinical and Health Psychology(2022). DOI: 10.10

Updated on:June 15,2024

Three-dimensional label-free morphology of CD8+ T cells as a sepsis biomarker

by Chinese Academy of Sciencesa, Schematic overview of the study workflow. Blood was sampled three times in the sepsis recovery cohort and once in the healthy control cohort. CD8+ T cells were ex

Updated on: April 09,2024

Three-dimensional label-free morphology of CD8+ T cells as a sepsis biomarker

by Chinese Academy of Sciencesa, Schematic overview of the study workflow. Blood was sampled three times in the sepsis recovery cohort and once in the healthy control cohort. CD8+ T cells were ex

Updated on:April 09,2024