Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on: June 06,2024

Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on:June 06,2024

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on: May 14,2024

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on:May 14,2024

Detecting pathogens faster and more accurately by melting DNA

by Ioana Patringenaru,University of California - San DiegoResearchers use this chip to analyze the microbes present in whole blood samples. Credit: David Baillot/University of California San Die

Updated on: April 23,2024

Detecting pathogens faster and more accurately by melting DNA

by Ioana Patringenaru,University of California - San DiegoResearchers use this chip to analyze the microbes present in whole blood samples. Credit: David Baillot/University of California San Die

Updated on:April 23,2024

New insights on B cells: Researchers explore building better antibodies and curbing autoimmune diseases

by Nancy Fliesler,Harvard Medical SchoolGb3 drives affinity and diversity of antibody responses and protects against viral infection. Credit:Science(2024). DOI: 10.1126/science.adg05

Updated on: April 28,2024

New insights on B cells: Researchers explore building better antibodies and curbing autoimmune diseases

by Nancy Fliesler,Harvard Medical SchoolGb3 drives affinity and diversity of antibody responses and protects against viral infection. Credit:Science(2024). DOI: 10.1126/science.adg05

Updated on:April 28,2024

Lymph node-like biomaterial scaffold for augmenting CAR-T cell therapy

byScience China PressOn the top, the schematic illustration shows the structure of scaffold, the seeding and proliferation of CAR-T cells within the scaffold after intratumor injection. On the b

Updated on: March 27,2024

Lymph node-like biomaterial scaffold for augmenting CAR-T cell therapy

byScience China PressOn the top, the schematic illustration shows the structure of scaffold, the seeding and proliferation of CAR-T cells within the scaffold after intratumor injection. On the b

Updated on:March 27,2024

SARS-CoV-2 curtails immune response in the gut

by European Molecular Biology LaboratoryThe researchers were able to monitor the virus's growth in organoids derived from human intestinal cells. Pink and red show areas of SARS-CoV-2 infecti

Updated on: April 22,2024

SARS-CoV-2 curtails immune response in the gut

by European Molecular Biology LaboratoryThe researchers were able to monitor the virus's growth in organoids derived from human intestinal cells. Pink and red show areas of SARS-CoV-2 infecti

Updated on:April 22,2024

Gender, high DAS28-P index predictive of pain in early RA

(HealthDay) -- For patients with rheumatoid arthritis (RA), female gender and having a high proportion of disease activity score (DAS28) attributable to patient-reported components (joint tenderness a

Updated on: April 08,2024

Gender, high DAS28-P index predictive of pain in early RA

(HealthDay) -- For patients with rheumatoid arthritis (RA), female gender and having a high proportion of disease activity score (DAS28) attributable to patient-reported components (joint tenderness a

Updated on:April 08,2024

Research into autoimmune liver condition suggests unique cell movements may drive disease

by University of BirminghamCD8+T cell internalization into BEC is a consistent event in PBC patients with ongoing disease. a) Representative fluorescence image of liver core biopsy, taken f

Updated on: March 07,2024

Research into autoimmune liver condition suggests unique cell movements may drive disease

by University of BirminghamCD8+T cell internalization into BEC is a consistent event in PBC patients with ongoing disease. a) Representative fluorescence image of liver core biopsy, taken f

Updated on:March 07,2024

Standardized treatment plans developed for new-onset JIA

Four standardized consensus treatment plans have been developed for patients with new-onset systemic juvenile idiopathic arthritis, according to research published in the July issue ofArthritis

Updated on: March 26,2024

Standardized treatment plans developed for new-onset JIA

Four standardized consensus treatment plans have been developed for patients with new-onset systemic juvenile idiopathic arthritis, according to research published in the July issue ofArthritis

Updated on:March 26,2024

Scientists discover two cellular defects appear to drive disease in lupus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine and Brigham and Women's Hospital scientists have discovered a molecular defect that promotes the pathologic im

Updated on: July 11,2024

Scientists discover two cellular defects appear to drive disease in lupus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine and Brigham and Women's Hospital scientists have discovered a molecular defect that promotes the pathologic im

Updated on:July 11,2024

Continuation vs. discontinuation of bDMARDs during the perioperative period

by Wolters Kluwer HealthCredit: Pixabay/CC0 Public DomainFor patients with rheumatic arthritis and other chronic inflammatory diseases, discontinuing biologic disease-modifying anti-rheumatic dru

Updated on: June 26,2024

Continuation vs. discontinuation of bDMARDs during the perioperative period

by Wolters Kluwer HealthCredit: Pixabay/CC0 Public DomainFor patients with rheumatic arthritis and other chronic inflammatory diseases, discontinuing biologic disease-modifying anti-rheumatic dru

Updated on:June 26,2024

OM85: How bacteria in a capsule could protect us from coronavirus and other respiratory infections

by Peter Sly,The ConversationCredit: AI-generated imageScientists around the world are continuing to test countless vaccines and drugs in the hope of finding effective ways to prevent and treat

Updated on: April 20,2024

OM85: How bacteria in a capsule could protect us from coronavirus and other respiratory infections

by Peter Sly,The ConversationCredit: AI-generated imageScientists around the world are continuing to test countless vaccines and drugs in the hope of finding effective ways to prevent and treat

Updated on:April 20,2024