Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on: May 14,2024

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on:May 14,2024

Standardized treatment plans developed for new-onset JIA

Four standardized consensus treatment plans have been developed for patients with new-onset systemic juvenile idiopathic arthritis, according to research published in the July issue ofArthritis

Updated on: March 26,2024

Standardized treatment plans developed for new-onset JIA

Four standardized consensus treatment plans have been developed for patients with new-onset systemic juvenile idiopathic arthritis, according to research published in the July issue ofArthritis

Updated on:March 26,2024

Air pollution linked to increased rheumatoid arthritis severity

(HealthDay)—Air pollution is associated with increased rheumatoid arthritis (RA) disease severity, according to a study published in the October issue ofRheumatology.Giovanni Adami, M.D., Ph.D.,

Updated on: June 01,2024

Air pollution linked to increased rheumatoid arthritis severity

(HealthDay)—Air pollution is associated with increased rheumatoid arthritis (RA) disease severity, according to a study published in the October issue ofRheumatology.Giovanni Adami, M.D., Ph.D.,

Updated on:June 01,2024

Study compares hospitalized infection risk for biologics in RA

(HealthDay)—For patients with rheumatoid arthritis (RA) with prior biologic exposure, the risk of hospitalized infection is increased with etanercept, infliximab, and rituximab versus abatacept, accor

Updated on: April 08,2024

Study compares hospitalized infection risk for biologics in RA

(HealthDay)—For patients with rheumatoid arthritis (RA) with prior biologic exposure, the risk of hospitalized infection is increased with etanercept, infliximab, and rituximab versus abatacept, accor

Updated on:April 08,2024

New study indicates why children are likelier to develop food allergies

by La Jolla Institute for Allergy and ImmunologyA study by LJI researchers identified a T cell population that renders normal food non-allergenic. Credit: La Jolla Institute for Allergy and Immun

Updated on: May 08,2024

New study indicates why children are likelier to develop food allergies

by La Jolla Institute for Allergy and ImmunologyA study by LJI researchers identified a T cell population that renders normal food non-allergenic. Credit: La Jolla Institute for Allergy and Immun

Updated on:May 08,2024

Study of T cells from COVID-19 convalescents guides vaccine strategies

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of the SARS-CoV-2-specific immune response kinetics. Memory T cells are maintained after recovery from COVID-19 with the

Updated on: April 10,2024

Study of T cells from COVID-19 convalescents guides vaccine strategies

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of the SARS-CoV-2-specific immune response kinetics. Memory T cells are maintained after recovery from COVID-19 with the

Updated on:April 10,2024

How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on: March 27,2024

How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on:March 27,2024

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on: June 15,2024

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on:June 15,2024

New study examines potential factors related to the development of adult-onset food allergy

by American College of Allergy, Asthma, and ImmunologyCredit: Pixabay/CC0 Public DomainIt's estimated that 33 million Americans have food allergies (FAs), including 5.6 million children under

Updated on: April 24,2024

New study examines potential factors related to the development of adult-onset food allergy

by American College of Allergy, Asthma, and ImmunologyCredit: Pixabay/CC0 Public DomainIt's estimated that 33 million Americans have food allergies (FAs), including 5.6 million children under

Updated on:April 24,2024

A new pathway to 'reprogram' killer cells

by University of BernNK cells (brown) patrolling between cells of a healthy human lymph node. Credit: Institute of Pathology, University of BernThe so-called natural killer (NK) cells are cells o

Updated on: May 08,2024

A new pathway to 'reprogram' killer cells

by University of BernNK cells (brown) patrolling between cells of a healthy human lymph node. Credit: Institute of Pathology, University of BernThe so-called natural killer (NK) cells are cells o

Updated on:May 08,2024

Study finds gut microbiota influence severity of respiratory viral infection

by Georgia State UniversityThis picture illustrates an example of gut microbiota composition dictating how resident lung alveolar macrophages (AM) respond to viral infection. The presence of segm

Updated on: March 07,2024

Study finds gut microbiota influence severity of respiratory viral infection

by Georgia State UniversityThis picture illustrates an example of gut microbiota composition dictating how resident lung alveolar macrophages (AM) respond to viral infection. The presence of segm

Updated on:March 07,2024

Possible new biomarker for better detection of numerous inflammatory diseases

by Kiel UniversityTryptophan concentrations in the blood were significantly reduced in 9 of 13 chronic inflammatory diseases examined. Credit: S. Klahn, Exzellenzcluster PMITryptophan is an essen

Updated on: March 30,2024

Possible new biomarker for better detection of numerous inflammatory diseases

by Kiel UniversityTryptophan concentrations in the blood were significantly reduced in 9 of 13 chronic inflammatory diseases examined. Credit: S. Klahn, Exzellenzcluster PMITryptophan is an essen

Updated on:March 30,2024