Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on: May 14,2024

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on:May 14,2024

Novel mechanism of ILC2 immune cell development may be involved in exacerbating allergic diseases

byChiba UniversityResearchers identify a G3SE-dependent mechanism of ILC2 development. Credit: Yosuke Toda and Arifumi Iwata from Chiba UniversityOverproduction of Group 2 innate lymphoid cells

Updated on: July 11,2024

Novel mechanism of ILC2 immune cell development may be involved in exacerbating allergic diseases

byChiba UniversityResearchers identify a G3SE-dependent mechanism of ILC2 development. Credit: Yosuke Toda and Arifumi Iwata from Chiba UniversityOverproduction of Group 2 innate lymphoid cells

Updated on:July 11,2024

Study compares hospitalized infection risk for biologics in RA

(HealthDay)—For patients with rheumatoid arthritis (RA) with prior biologic exposure, the risk of hospitalized infection is increased with etanercept, infliximab, and rituximab versus abatacept, accor

Updated on: April 08,2024

Study compares hospitalized infection risk for biologics in RA

(HealthDay)—For patients with rheumatoid arthritis (RA) with prior biologic exposure, the risk of hospitalized infection is increased with etanercept, infliximab, and rituximab versus abatacept, accor

Updated on:April 08,2024

Possible new biomarker for better detection of numerous inflammatory diseases

by Kiel UniversityTryptophan concentrations in the blood were significantly reduced in 9 of 13 chronic inflammatory diseases examined. Credit: S. Klahn, Exzellenzcluster PMITryptophan is an essen

Updated on: March 30,2024

Possible new biomarker for better detection of numerous inflammatory diseases

by Kiel UniversityTryptophan concentrations in the blood were significantly reduced in 9 of 13 chronic inflammatory diseases examined. Credit: S. Klahn, Exzellenzcluster PMITryptophan is an essen

Updated on:March 30,2024

Boosting CAR-T cell therapies from under the skin

by Benjamin Boettner,Harvard UniversityT-cell enhancing scaffolds can be locally injected under the skin following CAR-T cell therapy, and allowcirculating CAR-T cells to infiltrate their 3-dime

Updated on: June 15,2024

Boosting CAR-T cell therapies from under the skin

by Benjamin Boettner,Harvard UniversityT-cell enhancing scaffolds can be locally injected under the skin following CAR-T cell therapy, and allowcirculating CAR-T cells to infiltrate their 3-dime

Updated on:June 15,2024

High-intensity strength training no added benefit for knee osteoarthritis

High-intensity strength training does not significantly improve knee pain with osteoarthritis compared with low-intensity strength training or a control condition, according to a study published in th

Updated on: May 29,2024

High-intensity strength training no added benefit for knee osteoarthritis

High-intensity strength training does not significantly improve knee pain with osteoarthritis compared with low-intensity strength training or a control condition, according to a study published in th

Updated on:May 29,2024

A safer treatment path for high-risk children to overcome food allergies

by University of British ColumbiaCredit: Unsplash/CC0 Public DomainNew research from the University of British Columbia reveals a safe path to overcoming food allergies for older children and oth

Updated on: March 07,2024

A safer treatment path for high-risk children to overcome food allergies

by University of British ColumbiaCredit: Unsplash/CC0 Public DomainNew research from the University of British Columbia reveals a safe path to overcoming food allergies for older children and oth

Updated on:March 07,2024

Study offers insight into management of patients who have interstitial pneumonia with autoimmune features

by UT Southwestern Medical CenterCredit: Unsplash/CC0 Public DomainInterstitial pneumonia with autoimmune features (IPAF) is a disease with many possible causes and no standard of care, making it

Updated on: June 01,2024

Study offers insight into management of patients who have interstitial pneumonia with autoimmune features

by UT Southwestern Medical CenterCredit: Unsplash/CC0 Public DomainInterstitial pneumonia with autoimmune features (IPAF) is a disease with many possible causes and no standard of care, making it

Updated on:June 01,2024

Back pain link to 24-hour body clock revealed

by University of ManchesterCredit: University of ManchesterNew research by University of Manchester scientists has for the first time shown that our spinal discs have 24-hour body clocks which wh

Updated on: March 24,2024

Back pain link to 24-hour body clock revealed

by University of ManchesterCredit: University of ManchesterNew research by University of Manchester scientists has for the first time shown that our spinal discs have 24-hour body clocks which wh

Updated on:March 24,2024

How the immune system becomes blind to cancer cells

by University of FreiburgCancer cells become invisible to the body's immune response. Unhindered by T cells (green), they can continue to replicate. Scientists have now described an important

Updated on: April 16,2024

How the immune system becomes blind to cancer cells

by University of FreiburgCancer cells become invisible to the body's immune response. Unhindered by T cells (green), they can continue to replicate. Scientists have now described an important

Updated on:April 16,2024

Here's why B cells benefit from booster shots

byRockefeller UniversityRecall germinal centers formed in response to a secondary infection generate a second line of defense, rebuffing memory B cells in favor of training naive ones. Credit: R

Updated on: October 10,2024

Here's why B cells benefit from booster shots

byRockefeller UniversityRecall germinal centers formed in response to a secondary infection generate a second line of defense, rebuffing memory B cells in favor of training naive ones. Credit: R

Updated on:October 10,2024

Experiments in infant mice suggest new way to prevent spread of flu in people

JANUARY 11, 2024byNYU Langone HealthCredit: Andrea Piacquadio from PexelsScientists have long known that some viruses and bacteria begin infections by latching first onto sugar molecules on the

Updated on: March 30,2024

Experiments in infant mice suggest new way to prevent spread of flu in people

JANUARY 11, 2024byNYU Langone HealthCredit: Andrea Piacquadio from PexelsScientists have long known that some viruses and bacteria begin infections by latching first onto sugar molecules on the

Updated on:March 30,2024