Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on: June 15,2024

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on:June 15,2024

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on: May 14,2024

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on:May 14,2024

How a plant-based diet can ease rheumatoid arthritis

by Nancy ClantonCredit: CC0 Public DomainSwitching to a plant-based diet can alleviate the pain caused by rheumatoid arthritis, a new study shows.Rheumatoid arthritis is a type of inflammatory polyart

Updated on: March 26,2024

How a plant-based diet can ease rheumatoid arthritis

by Nancy ClantonCredit: CC0 Public DomainSwitching to a plant-based diet can alleviate the pain caused by rheumatoid arthritis, a new study shows.Rheumatoid arthritis is a type of inflammatory polyart

Updated on:March 26,2024

Novel mechanism of ILC2 immune cell development may be involved in exacerbating allergic diseases

byChiba UniversityResearchers identify a G3SE-dependent mechanism of ILC2 development. Credit: Yosuke Toda and Arifumi Iwata from Chiba UniversityOverproduction of Group 2 innate lymphoid cells

Updated on: July 11,2024

Novel mechanism of ILC2 immune cell development may be involved in exacerbating allergic diseases

byChiba UniversityResearchers identify a G3SE-dependent mechanism of ILC2 development. Credit: Yosuke Toda and Arifumi Iwata from Chiba UniversityOverproduction of Group 2 innate lymphoid cells

Updated on:July 11,2024

Boosting CAR-T cell therapies from under the skin

by Benjamin Boettner,Harvard UniversityT-cell enhancing scaffolds can be locally injected under the skin following CAR-T cell therapy, and allowcirculating CAR-T cells to infiltrate their 3-dime

Updated on: June 15,2024

Boosting CAR-T cell therapies from under the skin

by Benjamin Boettner,Harvard UniversityT-cell enhancing scaffolds can be locally injected under the skin following CAR-T cell therapy, and allowcirculating CAR-T cells to infiltrate their 3-dime

Updated on:June 15,2024

Rituximab retreatment at clinical relapse cost-effective in RA

(HealthDay)—Rituximab retreatment at clinical relapse is at least as cost-effective as a more intensive regimen in longstanding rheumatoid arthritis (RA), according to a study published in the July is

Updated on: April 08,2024

Rituximab retreatment at clinical relapse cost-effective in RA

(HealthDay)—Rituximab retreatment at clinical relapse is at least as cost-effective as a more intensive regimen in longstanding rheumatoid arthritis (RA), according to a study published in the July is

Updated on:April 08,2024

Researchers discover immune system changes that support peanut allergy remission in children

by Murdoch Children's Research InstituteResearchers have discovered the key immunological changes that support the remission of peanut allergy in children, paving the way for new, more target

Updated on: May 05,2024

Researchers discover immune system changes that support peanut allergy remission in children

by Murdoch Children's Research InstituteResearchers have discovered the key immunological changes that support the remission of peanut allergy in children, paving the way for new, more target

Updated on:May 05,2024

COVID-19 vaccines produce antibody response in the nasal mucosa

by University of North Carolina Health CarePre-immunity and post-immunity SARS-CoV-2 virus-specific IgG and IgA antibody concentrations in NELF and serum. Antibody concentrations were reported as

Updated on: April 13,2024

COVID-19 vaccines produce antibody response in the nasal mucosa

by University of North Carolina Health CarePre-immunity and post-immunity SARS-CoV-2 virus-specific IgG and IgA antibody concentrations in NELF and serum. Antibody concentrations were reported as

Updated on:April 13,2024

A gene that plays a critical role in natural killer cell differentiation

by Bob Yirka , Medical XpressAn illustration of natural killer cells. Credit: Val Altounian / AAASA large team of researchers affiliated with a host of institutions in Europe and the U.S. has found a

Updated on: March 25,2024

A gene that plays a critical role in natural killer cell differentiation

by Bob Yirka , Medical XpressAn illustration of natural killer cells. Credit: Val Altounian / AAASA large team of researchers affiliated with a host of institutions in Europe and the U.S. has found a

Updated on:March 25,2024

Biomarkers may ID rheumatoid arthritis patients with and without active disease

Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) values may differentiate between rheumatoid arthritis (RA) patients with and without active disease, according to a systemat

Updated on: May 29,2024

Biomarkers may ID rheumatoid arthritis patients with and without active disease

Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) values may differentiate between rheumatoid arthritis (RA) patients with and without active disease, according to a systemat

Updated on:May 29,2024

Back pain link to 24-hour body clock revealed

by University of ManchesterCredit: University of ManchesterNew research by University of Manchester scientists has for the first time shown that our spinal discs have 24-hour body clocks which wh

Updated on: March 24,2024

Back pain link to 24-hour body clock revealed

by University of ManchesterCredit: University of ManchesterNew research by University of Manchester scientists has for the first time shown that our spinal discs have 24-hour body clocks which wh

Updated on:March 24,2024

Preclinical study of COVID-19 vaccine candidate shows potent T-cell responses

by University of Alabama at BirminghamCredit: University of Alabama at BirminghamPreclinical studies of a COVID-19 vaccine candidate at the University of Alabama at Birmingham show positive resul

Updated on: April 10,2024

Preclinical study of COVID-19 vaccine candidate shows potent T-cell responses

by University of Alabama at BirminghamCredit: University of Alabama at BirminghamPreclinical studies of a COVID-19 vaccine candidate at the University of Alabama at Birmingham show positive resul

Updated on:April 10,2024