Nasopharyngeal carcinoma treatment using exosomes derived from γδ-T cells synergized with radiotherapy

by The University of Hong KongExos induce apoptosis of NPC tumor cells through death receptor ligation. NPC43 or C666-1 cells were treated with PBS, ultracentrifuged pellets isolated from FBS–exo

Updated on: May 07,2024

Nasopharyngeal carcinoma treatment using exosomes derived from γδ-T cells synergized with radiotherapy

by The University of Hong KongExos induce apoptosis of NPC tumor cells through death receptor ligation. NPC43 or C666-1 cells were treated with PBS, ultracentrifuged pellets isolated from FBS–exo

Updated on:May 07,2024

Why COVID patients become critically ill

by University of AmsterdamCredit: Unsplash/CC0 Public DomainResearchers at Amsterdam UMC have discovered why patients become seriously ill after being infected with the coronavirus. They identifi

Updated on: April 09,2024

Why COVID patients become critically ill

by University of AmsterdamCredit: Unsplash/CC0 Public DomainResearchers at Amsterdam UMC have discovered why patients become seriously ill after being infected with the coronavirus. They identifi

Updated on:April 09,2024

Does COVID-19 vaccination affect rheumatic and musculoskeletal disease flares?

by WileyCredit: CC0 Public DomainIn a study of 1,377 patients with rheumatic and musculoskeletal diseases—such as inflammatory arthritis and lupus—flares of their conditions were uncommon followi

Updated on: June 26,2024

Does COVID-19 vaccination affect rheumatic and musculoskeletal disease flares?

by WileyCredit: CC0 Public DomainIn a study of 1,377 patients with rheumatic and musculoskeletal diseases—such as inflammatory arthritis and lupus—flares of their conditions were uncommon followi

Updated on:June 26,2024

How B cells fight the COVID-19 virus

by Sarah C.p. Williams,Broad Institute of MIT and HarvardResearchers discovered a new antibody (light blue) that neutralizes the COVID-19 virus, by binding to the virus’s spike protein (grey) an

Updated on: April 08,2024

How B cells fight the COVID-19 virus

by Sarah C.p. Williams,Broad Institute of MIT and HarvardResearchers discovered a new antibody (light blue) that neutralizes the COVID-19 virus, by binding to the virus’s spike protein (grey) an

Updated on:April 08,2024

Adults with lupus, common types of arthritis have similar risks of getting admitted to hospital as other COVID patients

by NYU Langone HealthCredit: Unsplash/CC0 Public DomainMost adults with systemic lupus erythematosus (SLE) are not at increased risk of hospitalization from COVID-19 due to medications used to da

Updated on: June 06,2024

Adults with lupus, common types of arthritis have similar risks of getting admitted to hospital as other COVID patients

by NYU Langone HealthCredit: Unsplash/CC0 Public DomainMost adults with systemic lupus erythematosus (SLE) are not at increased risk of hospitalization from COVID-19 due to medications used to da

Updated on:June 06,2024

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on: January 11,2025

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on:January 11,2025

Unique immune response found in patients who experience inflammatory arthritis as side effect of cancer therapies

by Brigham and Women's HospitalMultiplexed immunofluorescence of synovial tissue. Multiplexed immunofluorescence images showing an example of a Ki67+PD-1+synovial CD8 T cell (white arro

Updated on: July 03,2024

Unique immune response found in patients who experience inflammatory arthritis as side effect of cancer therapies

by Brigham and Women's HospitalMultiplexed immunofluorescence of synovial tissue. Multiplexed immunofluorescence images showing an example of a Ki67+PD-1+synovial CD8 T cell (white arro

Updated on:July 03,2024

COVID-19 virus helps block host immunity

by Mary Ann Liebert, IncSARS-CoV-2 (shown here in an electron microscopy image). Credit: National Institute of Allergy and Infectious Diseases, NIHSARS-CoV-2, the virus that causes COVID-19, bloc

Updated on: April 10,2024

COVID-19 virus helps block host immunity

by Mary Ann Liebert, IncSARS-CoV-2 (shown here in an electron microscopy image). Credit: National Institute of Allergy and Infectious Diseases, NIHSARS-CoV-2, the virus that causes COVID-19, bloc

Updated on:April 10,2024

Common sites of bone erosion in rheumatoid arthritis

(HealthDay)—Joint recesses with bone erosion are more likely to exhibit greater severity of joint inflammation on ultrasound (US) examination, according to a study published online Oct. 25 in the&nbsp

Updated on: May 08,2024

Common sites of bone erosion in rheumatoid arthritis

(HealthDay)—Joint recesses with bone erosion are more likely to exhibit greater severity of joint inflammation on ultrasound (US) examination, according to a study published online Oct. 25 in the&nbsp

Updated on:May 08,2024

Lymph node-like biomaterial scaffold for augmenting CAR-T cell therapy

byScience China PressOn the top, the schematic illustration shows the structure of scaffold, the seeding and proliferation of CAR-T cells within the scaffold after intratumor injection. On the b

Updated on: March 27,2024

Lymph node-like biomaterial scaffold for augmenting CAR-T cell therapy

byScience China PressOn the top, the schematic illustration shows the structure of scaffold, the seeding and proliferation of CAR-T cells within the scaffold after intratumor injection. On the b

Updated on:March 27,2024

Nrf2: The custodian regulating oxidative stress and immunity against acrylamide toxicity

by Tokyo University of ScienceGenetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice. Credit: Tokyo University of ScienceAcrylamide is a toxic chemical compound that affect

Updated on: April 20,2024

Nrf2: The custodian regulating oxidative stress and immunity against acrylamide toxicity

by Tokyo University of ScienceGenetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice. Credit: Tokyo University of ScienceAcrylamide is a toxic chemical compound that affect

Updated on:April 20,2024

Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on: June 06,2024

Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on:June 06,2024