Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on: June 15,2024

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on:June 15,2024

A gene that plays a critical role in natural killer cell differentiation

by Bob Yirka , Medical XpressAn illustration of natural killer cells. Credit: Val Altounian / AAASA large team of researchers affiliated with a host of institutions in Europe and the U.S. has found a

Updated on: March 25,2024

A gene that plays a critical role in natural killer cell differentiation

by Bob Yirka , Medical XpressAn illustration of natural killer cells. Credit: Val Altounian / AAASA large team of researchers affiliated with a host of institutions in Europe and the U.S. has found a

Updated on:March 25,2024

Study reveals new role for inflammatory protein in fat tissue

byKarolinska InstitutetMicroscope image of fat cells. Credit: Kaisa HofwimmerA new studypublishedinNature Communicationsshows that the inflammatory protein IL-1β has an i

Updated on: October 30,2024

Study reveals new role for inflammatory protein in fat tissue

byKarolinska InstitutetMicroscope image of fat cells. Credit: Kaisa HofwimmerA new studypublishedinNature Communicationsshows that the inflammatory protein IL-1β has an i

Updated on:October 30,2024

Post-COVID-19 conditions alter a person's immune response

by Cedars-Sinai Medical CenterCredit: Unsplash/CC0 Public DomainA new study by investigators from the Smidt Heart Institute at Cedars-Sinai suggests long COVID-19 might be caused by a dysfunction

Updated on: April 09,2024

Post-COVID-19 conditions alter a person's immune response

by Cedars-Sinai Medical CenterCredit: Unsplash/CC0 Public DomainA new study by investigators from the Smidt Heart Institute at Cedars-Sinai suggests long COVID-19 might be caused by a dysfunction

Updated on:April 09,2024

CAR T cell therapies may lead to reactivation of childhood viral infections

by Justin Jackson , Medical XpressPetabase-scale analysis of viral nucleic acids reveals that HHV-6 is reactivated in human T cells. a, Schematic of life cycles of endogenous human viruses. Viruses ca

Updated on: April 09,2024

CAR T cell therapies may lead to reactivation of childhood viral infections

by Justin Jackson , Medical XpressPetabase-scale analysis of viral nucleic acids reveals that HHV-6 is reactivated in human T cells. a, Schematic of life cycles of endogenous human viruses. Viruses ca

Updated on:April 09,2024

OM85: How bacteria in a capsule could protect us from coronavirus and other respiratory infections

by Peter Sly,The ConversationCredit: AI-generated imageScientists around the world are continuing to test countless vaccines and drugs in the hope of finding effective ways to prevent and treat

Updated on: April 20,2024

OM85: How bacteria in a capsule could protect us from coronavirus and other respiratory infections

by Peter Sly,The ConversationCredit: AI-generated imageScientists around the world are continuing to test countless vaccines and drugs in the hope of finding effective ways to prevent and treat

Updated on:April 20,2024

How intravenous immunoglobulin antibodies resolve joint inflammation in rheumatoid arthritis

by Friedrich–Alexander University Erlangen–NurnbergGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.02.019Immunoglobulin G antibodies (IgB) play an important role

Updated on: June 17,2024

How intravenous immunoglobulin antibodies resolve joint inflammation in rheumatoid arthritis

by Friedrich–Alexander University Erlangen–NurnbergGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.02.019Immunoglobulin G antibodies (IgB) play an important role

Updated on:June 17,2024

Autoimmune diseases in ALS patients linked to genetic mutation

by Sarah Lichtman,Cedars-Sinai Medical CenterRobert Baloh, MD, PhD, at work in his laboratory. Credit: Cedars-SinaiA study published today in the journalNaturecould help explain why

Updated on: April 08,2024

Autoimmune diseases in ALS patients linked to genetic mutation

by Sarah Lichtman,Cedars-Sinai Medical CenterRobert Baloh, MD, PhD, at work in his laboratory. Credit: Cedars-SinaiA study published today in the journalNaturecould help explain why

Updated on:April 08,2024

New study examines potential factors related to the development of adult-onset food allergy

by American College of Allergy, Asthma, and ImmunologyCredit: Pixabay/CC0 Public DomainIt's estimated that 33 million Americans have food allergies (FAs), including 5.6 million children under

Updated on: April 24,2024

New study examines potential factors related to the development of adult-onset food allergy

by American College of Allergy, Asthma, and ImmunologyCredit: Pixabay/CC0 Public DomainIt's estimated that 33 million Americans have food allergies (FAs), including 5.6 million children under

Updated on:April 24,2024

How the immune system becomes blind to cancer cells

by University of FreiburgCancer cells become invisible to the body's immune response. Unhindered by T cells (green), they can continue to replicate. Scientists have now described an important

Updated on: April 16,2024

How the immune system becomes blind to cancer cells

by University of FreiburgCancer cells become invisible to the body's immune response. Unhindered by T cells (green), they can continue to replicate. Scientists have now described an important

Updated on:April 16,2024

Certain steps help lead to healthy pregnancies in women with rheumatoid arthritis

by WileyCredit: CC0 Public DomainFor women with rheumatoid arthritis (RA), taking certain steps to ensure that they have a healthy pregnancy leads to a reduced risk of complicated birth or miscar

Updated on: April 17,2024

Certain steps help lead to healthy pregnancies in women with rheumatoid arthritis

by WileyCredit: CC0 Public DomainFor women with rheumatoid arthritis (RA), taking certain steps to ensure that they have a healthy pregnancy leads to a reduced risk of complicated birth or miscar

Updated on:April 17,2024

Continuation vs. discontinuation of bDMARDs during the perioperative period

by Wolters Kluwer HealthCredit: Pixabay/CC0 Public DomainFor patients with rheumatic arthritis and other chronic inflammatory diseases, discontinuing biologic disease-modifying anti-rheumatic dru

Updated on: June 26,2024

Continuation vs. discontinuation of bDMARDs during the perioperative period

by Wolters Kluwer HealthCredit: Pixabay/CC0 Public DomainFor patients with rheumatic arthritis and other chronic inflammatory diseases, discontinuing biologic disease-modifying anti-rheumatic dru

Updated on:June 26,2024