How B cells are programmed early in life can impact long-term immune health

by Lund UniversityGraphical abstract. Credit:Immunity(2022). DOI: 10.1016/j.immuni.2022.08.018B cells and the antibodies they produce play an important role in our immune system, prot

Updated on: April 08,2024

How B cells are programmed early in life can impact long-term immune health

by Lund UniversityGraphical abstract. Credit:Immunity(2022). DOI: 10.1016/j.immuni.2022.08.018B cells and the antibodies they produce play an important role in our immune system, prot

Updated on:April 08,2024

A gene that plays a critical role in natural killer cell differentiation

by Bob Yirka , Medical XpressAn illustration of natural killer cells. Credit: Val Altounian / AAASA large team of researchers affiliated with a host of institutions in Europe and the U.S. has found a

Updated on: March 25,2024

A gene that plays a critical role in natural killer cell differentiation

by Bob Yirka , Medical XpressAn illustration of natural killer cells. Credit: Val Altounian / AAASA large team of researchers affiliated with a host of institutions in Europe and the U.S. has found a

Updated on:March 25,2024

Nasopharyngeal carcinoma treatment using exosomes derived from γδ-T cells synergized with radiotherapy

by The University of Hong KongExos induce apoptosis of NPC tumor cells through death receptor ligation. NPC43 or C666-1 cells were treated with PBS, ultracentrifuged pellets isolated from FBS–exo

Updated on: May 07,2024

Nasopharyngeal carcinoma treatment using exosomes derived from γδ-T cells synergized with radiotherapy

by The University of Hong KongExos induce apoptosis of NPC tumor cells through death receptor ligation. NPC43 or C666-1 cells were treated with PBS, ultracentrifuged pellets isolated from FBS–exo

Updated on:May 07,2024

Guidelines issued for vaccination in patients with rheumatic, musculoskeletal diseases

In new guidelines issued by the American College of Rheumatology, evidence-based recommendations are presented for the use of vaccinations in children and adults with rheumatic and musculoskeletal dis

Updated on: June 15,2024

Guidelines issued for vaccination in patients with rheumatic, musculoskeletal diseases

In new guidelines issued by the American College of Rheumatology, evidence-based recommendations are presented for the use of vaccinations in children and adults with rheumatic and musculoskeletal dis

Updated on:June 15,2024

Depemokimab cuts exacerbation rate in eosinophilic asthma

by Elana GotkineFor patients with severe asthma with an eosinophilic phenotype, depemokimab reduces the annualized rate of exacerbations, according to a studypublishedonline Sept. 9 in the

Updated on: October 01,2024

Depemokimab cuts exacerbation rate in eosinophilic asthma

by Elana GotkineFor patients with severe asthma with an eosinophilic phenotype, depemokimab reduces the annualized rate of exacerbations, according to a studypublishedonline Sept. 9 in the

Updated on:October 01,2024

Early combined treatment with biologic and conventional DMARDs could be effective for polyarticular juvenile arthritis

by American College of RheumatologyCredit: CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that patients sta

Updated on: March 28,2024

Early combined treatment with biologic and conventional DMARDs could be effective for polyarticular juvenile arthritis

by American College of RheumatologyCredit: CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that patients sta

Updated on:March 28,2024

Platelet-rich plasma treatment shows efficacy for osteoarthritis

by Homa Shalchi,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainA pilot study conducted by researchers at Baylor College of Medicine combined wearable technology and patient-reported

Updated on: May 26,2024

Platelet-rich plasma treatment shows efficacy for osteoarthritis

by Homa Shalchi,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainA pilot study conducted by researchers at Baylor College of Medicine combined wearable technology and patient-reported

Updated on:May 26,2024

How the immune system becomes blind to cancer cells

by University of FreiburgCancer cells become invisible to the body's immune response. Unhindered by T cells (green), they can continue to replicate. Scientists have now described an important

Updated on: April 16,2024

How the immune system becomes blind to cancer cells

by University of FreiburgCancer cells become invisible to the body's immune response. Unhindered by T cells (green), they can continue to replicate. Scientists have now described an important

Updated on:April 16,2024

Certain steps help lead to healthy pregnancies in women with rheumatoid arthritis

by WileyCredit: CC0 Public DomainFor women with rheumatoid arthritis (RA), taking certain steps to ensure that they have a healthy pregnancy leads to a reduced risk of complicated birth or miscar

Updated on: April 17,2024

Certain steps help lead to healthy pregnancies in women with rheumatoid arthritis

by WileyCredit: CC0 Public DomainFor women with rheumatoid arthritis (RA), taking certain steps to ensure that they have a healthy pregnancy leads to a reduced risk of complicated birth or miscar

Updated on:April 17,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on: May 07,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on:May 07,2024

CAR T cell therapies may lead to reactivation of childhood viral infections

by Justin Jackson , Medical XpressPetabase-scale analysis of viral nucleic acids reveals that HHV-6 is reactivated in human T cells. a, Schematic of life cycles of endogenous human viruses. Viruses ca

Updated on: April 09,2024

CAR T cell therapies may lead to reactivation of childhood viral infections

by Justin Jackson , Medical XpressPetabase-scale analysis of viral nucleic acids reveals that HHV-6 is reactivated in human T cells. a, Schematic of life cycles of endogenous human viruses. Viruses ca

Updated on:April 09,2024

Fecal microbiota transplantation for active peripheral psoriatic arthritis shows no advantage

by European Alliance of Associations for RheumatologyCredit: CC0 Public DomainIn this proof-of-concept study, Maja Skov Kragsnaes and colleagues evaluated efficacy and safety of FMT in people with pso

Updated on: June 17,2024

Fecal microbiota transplantation for active peripheral psoriatic arthritis shows no advantage

by European Alliance of Associations for RheumatologyCredit: CC0 Public DomainIn this proof-of-concept study, Maja Skov Kragsnaes and colleagues evaluated efficacy and safety of FMT in people with pso

Updated on:June 17,2024