Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on: June 06,2024

Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on:June 06,2024

Researchers find genetic association for interstitial lung disease

by University of TsukubaMUC5B risk allele carrier frequency in ANCA-associated vasculitis (AAV) with and without interstitial lung disease (ILD) as well as in healthy controls in the Japanese pop

Updated on: May 19,2024

Researchers find genetic association for interstitial lung disease

by University of TsukubaMUC5B risk allele carrier frequency in ANCA-associated vasculitis (AAV) with and without interstitial lung disease (ILD) as well as in healthy controls in the Japanese pop

Updated on:May 19,2024

Study reveals new role for inflammatory protein in fat tissue

byKarolinska InstitutetMicroscope image of fat cells. Credit: Kaisa HofwimmerA new studypublishedinNature Communicationsshows that the inflammatory protein IL-1β has an i

Updated on: October 30,2024

Study reveals new role for inflammatory protein in fat tissue

byKarolinska InstitutetMicroscope image of fat cells. Credit: Kaisa HofwimmerA new studypublishedinNature Communicationsshows that the inflammatory protein IL-1β has an i

Updated on:October 30,2024

Experiments in infant mice suggest new way to prevent spread of flu in people

JANUARY 11, 2024byNYU Langone HealthCredit: Andrea Piacquadio from PexelsScientists have long known that some viruses and bacteria begin infections by latching first onto sugar molecules on the

Updated on: March 30,2024

Experiments in infant mice suggest new way to prevent spread of flu in people

JANUARY 11, 2024byNYU Langone HealthCredit: Andrea Piacquadio from PexelsScientists have long known that some viruses and bacteria begin infections by latching first onto sugar molecules on the

Updated on:March 30,2024

Is it brain infection or cancer? A new rapid test could hold the answer

by Thomas Jefferson UniversityGram stain of meningococci from a culture showing Gram negative (pink) bacteria, often in pairs. Credit: public domainWhen patients present with neurologic symptoms

Updated on: April 16,2024

Is it brain infection or cancer? A new rapid test could hold the answer

by Thomas Jefferson UniversityGram stain of meningococci from a culture showing Gram negative (pink) bacteria, often in pairs. Credit: public domainWhen patients present with neurologic symptoms

Updated on:April 16,2024

Lower RA activity for patients seen at practices with NPs, PAs

(HealthDay)—Patients with rheumatoid arthritis (RA) have lower disease activity when seen at practices with nurse practitioners (NPs) or physician assistants (PAs) versus rheumatologist-only practices

Updated on: March 24,2024

Lower RA activity for patients seen at practices with NPs, PAs

(HealthDay)—Patients with rheumatoid arthritis (RA) have lower disease activity when seen at practices with nurse practitioners (NPs) or physician assistants (PAs) versus rheumatologist-only practices

Updated on:March 24,2024

Unique immune response found in patients who experience inflammatory arthritis as side effect of cancer therapies

by Brigham and Women's HospitalMultiplexed immunofluorescence of synovial tissue. Multiplexed immunofluorescence images showing an example of a Ki67+PD-1+synovial CD8 T cell (white arro

Updated on: July 03,2024

Unique immune response found in patients who experience inflammatory arthritis as side effect of cancer therapies

by Brigham and Women's HospitalMultiplexed immunofluorescence of synovial tissue. Multiplexed immunofluorescence images showing an example of a Ki67+PD-1+synovial CD8 T cell (white arro

Updated on:July 03,2024

X chromosome gene may explain why women are more prone to autoimmune diseases

by Alice Walton,University of California, Los Angeles(A) Using the high-throughput sequencing approach, sexually biased X chromosome genes in CD4+T cells were determined for C57BL/6J naive

Updated on: May 05,2024

X chromosome gene may explain why women are more prone to autoimmune diseases

by Alice Walton,University of California, Los Angeles(A) Using the high-throughput sequencing approach, sexually biased X chromosome genes in CD4+T cells were determined for C57BL/6J naive

Updated on:May 05,2024

Covert tactics used by bacteria to trick human immune system

by McMaster UniversityBrian Coombes in his lab at McMaster University. Credit: McMaster UniversityMcMaster University researchers have found a new way bacteria evade the human immune system and p

Updated on: April 09,2024

Covert tactics used by bacteria to trick human immune system

by McMaster UniversityBrian Coombes in his lab at McMaster University. Credit: McMaster UniversityMcMaster University researchers have found a new way bacteria evade the human immune system and p

Updated on:April 09,2024

Weekly leflunomide effective for early rheumatoid arthritis

(HealthDay)—A higher, weekly dose of leflunomide shows similar benefits to a daily dose for the treatment of mild-to-moderate early rheumatoid arthritis (ERA), according to a study published online Au

Updated on: April 08,2024

Weekly leflunomide effective for early rheumatoid arthritis

(HealthDay)—A higher, weekly dose of leflunomide shows similar benefits to a daily dose for the treatment of mild-to-moderate early rheumatoid arthritis (ERA), according to a study published online Au

Updated on:April 08,2024

Key type of immune cell 'self-renews' in humans, new study finds

by Cardiff UniversityCredit: CC0 Public DomainA team of scientists has shown that a key type of immune cell "self-renews" in humans.It is an unexpected discovery, as it was previously t

Updated on: April 24,2024

Key type of immune cell 'self-renews' in humans, new study finds

by Cardiff UniversityCredit: CC0 Public DomainA team of scientists has shown that a key type of immune cell "self-renews" in humans.It is an unexpected discovery, as it was previously t

Updated on:April 24,2024

A small mutation can make Zika virus even more dangerous

by La Jolla Institute for ImmunologyRepeatedly switching back and forth between mosquito cells and mice provided scientists with a window into how Zika virus naturally evolves as it encounters mo

Updated on: April 24,2024

A small mutation can make Zika virus even more dangerous

by La Jolla Institute for ImmunologyRepeatedly switching back and forth between mosquito cells and mice provided scientists with a window into how Zika virus naturally evolves as it encounters mo

Updated on:April 24,2024