Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on: June 06,2024

Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on:June 06,2024

How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on: March 27,2024

How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on:March 27,2024

AI model can quantify radiographic joint damage in rheumatoid arthritis

An international competition resulted in the development of algorithms that provide feasible, quick, and accurate methods to quantify joint damage in rheumatoid arthritis (RA), according to a study pu

Updated on: June 26,2024

AI model can quantify radiographic joint damage in rheumatoid arthritis

An international competition resulted in the development of algorithms that provide feasible, quick, and accurate methods to quantify joint damage in rheumatoid arthritis (RA), according to a study pu

Updated on:June 26,2024

Experiments in infant mice suggest new way to prevent spread of flu in people

JANUARY 11, 2024byNYU Langone HealthCredit: Andrea Piacquadio from PexelsScientists have long known that some viruses and bacteria begin infections by latching first onto sugar molecules on the

Updated on: March 30,2024

Experiments in infant mice suggest new way to prevent spread of flu in people

JANUARY 11, 2024byNYU Langone HealthCredit: Andrea Piacquadio from PexelsScientists have long known that some viruses and bacteria begin infections by latching first onto sugar molecules on the

Updated on:March 30,2024

Key type of immune cell 'self-renews' in humans, new study finds

by Cardiff UniversityCredit: CC0 Public DomainA team of scientists has shown that a key type of immune cell "self-renews" in humans.It is an unexpected discovery, as it was previously t

Updated on: April 24,2024

Key type of immune cell 'self-renews' in humans, new study finds

by Cardiff UniversityCredit: CC0 Public DomainA team of scientists has shown that a key type of immune cell "self-renews" in humans.It is an unexpected discovery, as it was previously t

Updated on:April 24,2024

Monash researchers bringing hope to lupus patients

by Monash UniversityResearchers at Monash University are leading the world's largest study to describe lupus patients and disease characteristics, bringing treat-to-target options for lupus a

Updated on: March 24,2024

Monash researchers bringing hope to lupus patients

by Monash UniversityResearchers at Monash University are leading the world's largest study to describe lupus patients and disease characteristics, bringing treat-to-target options for lupus a

Updated on:March 24,2024

COVID-19 vaccines produce antibody response in the nasal mucosa

by University of North Carolina Health CarePre-immunity and post-immunity SARS-CoV-2 virus-specific IgG and IgA antibody concentrations in NELF and serum. Antibody concentrations were reported as

Updated on: April 13,2024

COVID-19 vaccines produce antibody response in the nasal mucosa

by University of North Carolina Health CarePre-immunity and post-immunity SARS-CoV-2 virus-specific IgG and IgA antibody concentrations in NELF and serum. Antibody concentrations were reported as

Updated on:April 13,2024

PFAS can suppress white blood cell's ability to destroy invaders

by Tracey Peake,North Carolina State UniversityPFASs used in this study. Names and structures of the PFASs used in this study. Vendors and CAS-RN numbers are provided in Table 1. Chemical struct

Updated on: April 20,2024

PFAS can suppress white blood cell's ability to destroy invaders

by Tracey Peake,North Carolina State UniversityPFASs used in this study. Names and structures of the PFASs used in this study. Vendors and CAS-RN numbers are provided in Table 1. Chemical struct

Updated on:April 20,2024

Is metabolic syndrome a modifiable risk factor for gout?

by WileyCredit: Pixabay/CC0 Public DomainIn a study published inArthritis & Rheumatologythat included nearly 1.3 million men aged 20–39 years who participated in three serial heal

Updated on: June 01,2024

Is metabolic syndrome a modifiable risk factor for gout?

by WileyCredit: Pixabay/CC0 Public DomainIn a study published inArthritis & Rheumatologythat included nearly 1.3 million men aged 20–39 years who participated in three serial heal

Updated on:June 01,2024

Early combined treatment with biologic and conventional DMARDs could be effective for polyarticular juvenile arthritis

by American College of RheumatologyCredit: CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that patients sta

Updated on: March 28,2024

Early combined treatment with biologic and conventional DMARDs could be effective for polyarticular juvenile arthritis

by American College of RheumatologyCredit: CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that patients sta

Updated on:March 28,2024

Here's why B cells benefit from booster shots

byRockefeller UniversityRecall germinal centers formed in response to a secondary infection generate a second line of defense, rebuffing memory B cells in favor of training naive ones. Credit: R

Updated on: October 10,2024

Here's why B cells benefit from booster shots

byRockefeller UniversityRecall germinal centers formed in response to a secondary infection generate a second line of defense, rebuffing memory B cells in favor of training naive ones. Credit: R

Updated on:October 10,2024

Autoimmune diseases in ALS patients linked to genetic mutation

by Sarah Lichtman,Cedars-Sinai Medical CenterRobert Baloh, MD, PhD, at work in his laboratory. Credit: Cedars-SinaiA study published today in the journalNaturecould help explain why

Updated on: April 08,2024

Autoimmune diseases in ALS patients linked to genetic mutation

by Sarah Lichtman,Cedars-Sinai Medical CenterRobert Baloh, MD, PhD, at work in his laboratory. Credit: Cedars-SinaiA study published today in the journalNaturecould help explain why

Updated on:April 08,2024