Nrf2: The custodian regulating oxidative stress and immunity against acrylamide toxicity

by Tokyo University of ScienceGenetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice. Credit: Tokyo University of ScienceAcrylamide is a toxic chemical compound that affect

Updated on: April 20,2024

Nrf2: The custodian regulating oxidative stress and immunity against acrylamide toxicity

by Tokyo University of ScienceGenetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice. Credit: Tokyo University of ScienceAcrylamide is a toxic chemical compound that affect

Updated on:April 20,2024

B cells gone bad could be the culprit in rheumatoid arthritis

by Laurie Fickman,University of HoustonBiomolecular researcher Navin Varadarajan anticipates that his data will serve as a foundation for investigating multiple hypotheses on the roles of B cell

Updated on: April 08,2024

B cells gone bad could be the culprit in rheumatoid arthritis

by Laurie Fickman,University of HoustonBiomolecular researcher Navin Varadarajan anticipates that his data will serve as a foundation for investigating multiple hypotheses on the roles of B cell

Updated on:April 08,2024

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on: January 11,2025

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on:January 11,2025

RA linked to restrictive, obstructive spirometry patterns

(HealthDay)—Rheumatoid arthritis (RA) is associated with restrictive and obstructive spirometry patterns, with the strongest associations seen for severe patterns, according to a study published onlin

Updated on: June 01,2024

RA linked to restrictive, obstructive spirometry patterns

(HealthDay)—Rheumatoid arthritis (RA) is associated with restrictive and obstructive spirometry patterns, with the strongest associations seen for severe patterns, according to a study published onlin

Updated on:June 01,2024

AID/APOBECs among important factors in body's defence against SARS-CoV-2

by Johannes Angerer,Medical University of ViennaCredit: Unsplash/CC0 Public DomainTogether with their multifaceted action mechanisms, activation-induced cytidine deaminase (AID) and so-called AP

Updated on: April 08,2024

AID/APOBECs among important factors in body's defence against SARS-CoV-2

by Johannes Angerer,Medical University of ViennaCredit: Unsplash/CC0 Public DomainTogether with their multifaceted action mechanisms, activation-induced cytidine deaminase (AID) and so-called AP

Updated on:April 08,2024

COVID-19 infection rates low in people with rheumatic diseases, most report mild illness

by American College of RheumatologyCredit: CC0 Public DomainA new study shows that the COVID-19 infection incidence has been low in people with rheumatic diseases, and most of those infected expe

Updated on: May 23,2024

COVID-19 infection rates low in people with rheumatic diseases, most report mild illness

by American College of RheumatologyCredit: CC0 Public DomainA new study shows that the COVID-19 infection incidence has been low in people with rheumatic diseases, and most of those infected expe

Updated on:May 23,2024

Study reveals new role for inflammatory protein in fat tissue

byKarolinska InstitutetMicroscope image of fat cells. Credit: Kaisa HofwimmerA new studypublishedinNature Communicationsshows that the inflammatory protein IL-1β has an i

Updated on: October 30,2024

Study reveals new role for inflammatory protein in fat tissue

byKarolinska InstitutetMicroscope image of fat cells. Credit: Kaisa HofwimmerA new studypublishedinNature Communicationsshows that the inflammatory protein IL-1β has an i

Updated on:October 30,2024

Serum IL-35 levels tied to bone loss with rheumatoid arthritis

Serum interleukin (IL)-35 levels are associated with bone loss and may represent a novel therapeutic target for postmenopausal women with rheumatoid arthritis (RA), according to a study published onli

Updated on: June 06,2024

Serum IL-35 levels tied to bone loss with rheumatoid arthritis

Serum interleukin (IL)-35 levels are associated with bone loss and may represent a novel therapeutic target for postmenopausal women with rheumatoid arthritis (RA), according to a study published onli

Updated on:June 06,2024

Scientists discover possible target for treating and preventing osteoarthritis

by University of FloridaCredit: CC0 Public DomainWear and tear on joints can lead to inflammation, breakdown of cartilage and development of osteoarthritis. Scientists at UF Scripps Biomedical Re

Updated on: April 17,2024

Scientists discover possible target for treating and preventing osteoarthritis

by University of FloridaCredit: CC0 Public DomainWear and tear on joints can lead to inflammation, breakdown of cartilage and development of osteoarthritis. Scientists at UF Scripps Biomedical Re

Updated on:April 17,2024

How intravenous immunoglobulin antibodies resolve joint inflammation in rheumatoid arthritis

by Friedrich–Alexander University Erlangen–NurnbergGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.02.019Immunoglobulin G antibodies (IgB) play an important role

Updated on: June 17,2024

How intravenous immunoglobulin antibodies resolve joint inflammation in rheumatoid arthritis

by Friedrich–Alexander University Erlangen–NurnbergGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.02.019Immunoglobulin G antibodies (IgB) play an important role

Updated on:June 17,2024

Bioluminescence technology reveals role of protein in immune response modulation

byUniversity of Western AustraliaCredit: Pixabay/CC0 Public DomainCutting-edge bioluminescence technology pioneered at The University of Western Australia has been used to uncover a potential ga

Updated on: March 27,2024

Bioluminescence technology reveals role of protein in immune response modulation

byUniversity of Western AustraliaCredit: Pixabay/CC0 Public DomainCutting-edge bioluminescence technology pioneered at The University of Western Australia has been used to uncover a potential ga

Updated on:March 27,2024

How changing gut microbiota can affect lupus disease activity in mice

by The Ohio State UniversityFigure 1. NZM2410 colonized with SFB exhibit intensified kidney disease with elevated immune-complex deposition. 10-week old mice were oral gavaged with fecal matter f

Updated on: June 20,2024

How changing gut microbiota can affect lupus disease activity in mice

by The Ohio State UniversityFigure 1. NZM2410 colonized with SFB exhibit intensified kidney disease with elevated immune-complex deposition. 10-week old mice were oral gavaged with fecal matter f

Updated on:June 20,2024