Urate transporter structures reveal the mechanism behind important drug target for gout

bySt. Jude Children's Research HospitalCryo-EM structures of human URAT1 in different functional states. Credit:Cell Research(2024). DOI: 10.1038/s41422-024-01023-1Scientists at

Updated on: September 15,2024 0

Urate transporter structures reveal the mechanism behind important drug target for gout

bySt. Jude Children's Research HospitalCryo-EM structures of human URAT1 in different functional states. Credit:Cell Research(2024). DOI: 10.1038/s41422-024-01023-1Scientists at

Updated on:September 15,2024 0

Impact of dietary interventions inconsistent in rheumatoid arthritis

(HealthDay)—For patients with rheumatoid arthritis (RA), the impact of dietary interventions is inconsistent, although some research indicates benefit for omega-3 supplementation, according to a revie

Updated on: April 07,2024 19

Impact of dietary interventions inconsistent in rheumatoid arthritis

(HealthDay)—For patients with rheumatoid arthritis (RA), the impact of dietary interventions is inconsistent, although some research indicates benefit for omega-3 supplementation, according to a revie

Updated on:April 07,2024 19

New study reveals how epithelial cells in the body naturally eliminate 'precancerous' ones

by Waseda UniversityWaseda University researchers identify the underlying mechanism behind the extrusion of precancerous cells by epithelial cells, a mechanism that prevents the formation of canc

Updated on: May 07,2024 19

New study reveals how epithelial cells in the body naturally eliminate 'precancerous' ones

by Waseda UniversityWaseda University researchers identify the underlying mechanism behind the extrusion of precancerous cells by epithelial cells, a mechanism that prevents the formation of canc

Updated on:May 07,2024 19

Can losing weight combat the structural defects of knee osteoarthritis?

by WileyCredit: CC0 Public DomainIn a study published inArthritis & Rheumatology, a decrease in body mass index (BMI) was associated with both a lower incidence of the structural defect

Updated on: May 19,2024 7

Can losing weight combat the structural defects of knee osteoarthritis?

by WileyCredit: CC0 Public DomainIn a study published inArthritis & Rheumatology, a decrease in body mass index (BMI) was associated with both a lower incidence of the structural defect

Updated on:May 19,2024 7

Upadacitinib beats placebo for psoriatic arthritis

For patients with psoriatic arthritis, upadacitinib at a dose of 15 mg or 30 mg once daily is more effective than placebo, according to a study published in the April 1 issue of theNew England J

Updated on: May 26,2024 8

Upadacitinib beats placebo for psoriatic arthritis

For patients with psoriatic arthritis, upadacitinib at a dose of 15 mg or 30 mg once daily is more effective than placebo, according to a study published in the April 1 issue of theNew England J

Updated on:May 26,2024 8

A bacterial toxin turning cells into swiss cheese

by Kanazawa UniversityResearchers from Kanazawa University developed a novel tool to study how the innate immune system fights bacterial toxins. They purified the pore-forming toxin Monalysin fro

Updated on: May 05,2024 20

A bacterial toxin turning cells into swiss cheese

by Kanazawa UniversityResearchers from Kanazawa University developed a novel tool to study how the innate immune system fights bacterial toxins. They purified the pore-forming toxin Monalysin fro

Updated on:May 05,2024 20

Chemical stimuli can support growing of stable cartilage cells

by Umea UniversityRho-kinase inhibition cause disappearance of cellular adhesion sites. The colors of the figure shows the staining for actin stress fibers (red), adhesion plaques-related vinculi

Updated on: May 08,2024 8

Chemical stimuli can support growing of stable cartilage cells

by Umea UniversityRho-kinase inhibition cause disappearance of cellular adhesion sites. The colors of the figure shows the staining for actin stress fibers (red), adhesion plaques-related vinculi

Updated on:May 08,2024 8

Macrophages produce heat from brown adipose tissue in response to cold, study reveals

by University of TsukubaGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113978Researchers from University of Tsukuba have elucidated the molecular mechanism

Updated on: March 27,2024 0

Macrophages produce heat from brown adipose tissue in response to cold, study reveals

by University of TsukubaGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113978Researchers from University of Tsukuba have elucidated the molecular mechanism

Updated on:March 27,2024 0

Physical activity and sleep in adults with arthritis

by WileyA new study published in Arthritis Care & Research has examined patterns of 24-hour physical activity and sleep among patients with rheumatoid arthritis, lupus, and knee osteoarthriti

Updated on: May 08,2024 7

Physical activity and sleep in adults with arthritis

by WileyA new study published in Arthritis Care & Research has examined patterns of 24-hour physical activity and sleep among patients with rheumatoid arthritis, lupus, and knee osteoarthriti

Updated on:May 08,2024 7

Findings give hope to plant extract as possible lupus treatment

by University of HoustonNew findings by UH biomedical engineer Chandra Mohan and his team raise hope for a new class of drugs to treat lupus that may not include the long list of adverse risks an

Updated on: June 15,2024 7

Findings give hope to plant extract as possible lupus treatment

by University of HoustonNew findings by UH biomedical engineer Chandra Mohan and his team raise hope for a new class of drugs to treat lupus that may not include the long list of adverse risks an

Updated on:June 15,2024 7

Trial shows timing matters when adding immunotherapy to chemoradiation for limited-stage small cell lung cancer

byAmerican Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainPeople with limited-stage small cell lung cancer may benefit from adding immunotherapy to chemoradiation, but not if bot

Updated on: October 26,2024 0

Trial shows timing matters when adding immunotherapy to chemoradiation for limited-stage small cell lung cancer

byAmerican Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainPeople with limited-stage small cell lung cancer may benefit from adding immunotherapy to chemoradiation, but not if bot

Updated on:October 26,2024 0

Severe reaction to pneumococcal vaccines in patients with CAPS

(HealthDay)—Pneumococcal vaccines can trigger a severe local and systemic inflammatory reaction in patients with cryopyrin-associated periodic syndromes (CAPS), according to a study published in the F

Updated on: April 17,2024 13

Severe reaction to pneumococcal vaccines in patients with CAPS

(HealthDay)—Pneumococcal vaccines can trigger a severe local and systemic inflammatory reaction in patients with cryopyrin-associated periodic syndromes (CAPS), according to a study published in the F

Updated on:April 17,2024 13