Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on: May 07,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on:May 07,2024

Low dose steroid use not associated with substantial weight gain or hypertension in patients with rheumatoid arthritis

by American College of PhysiciansCredit: Unsplash/CC0 Public DomainAn analysis of randomized controlled trials has found that the use of low-dose glucocorticoids was not associated with substanti

Updated on: June 17,2024

Low dose steroid use not associated with substantial weight gain or hypertension in patients with rheumatoid arthritis

by American College of PhysiciansCredit: Unsplash/CC0 Public DomainAn analysis of randomized controlled trials has found that the use of low-dose glucocorticoids was not associated with substanti

Updated on:June 17,2024

In veterans with RA, PTSD worsens disease activity

For U.S. veterans with rheumatoid arthritis, a diagnosis of posttraumatic stress disorder is associated with worse patient-reported outcomes and tender joint counts, according to a study published onl

Updated on: March 30,2024

In veterans with RA, PTSD worsens disease activity

For U.S. veterans with rheumatoid arthritis, a diagnosis of posttraumatic stress disorder is associated with worse patient-reported outcomes and tender joint counts, according to a study published onl

Updated on:March 30,2024

Study finds half of patients with low-grade proteinuria develop treatable lupus nephritis within two years

by American College of RheumatologyCredit: Short- and Long-Term Progression of Kidney Involvement in Systemic Lupus Erythematosus Patients with Low-Grade Proteinuria (2022) https://acrabstracts.o

Updated on: May 08,2024

Study finds half of patients with low-grade proteinuria develop treatable lupus nephritis within two years

by American College of RheumatologyCredit: Short- and Long-Term Progression of Kidney Involvement in Systemic Lupus Erythematosus Patients with Low-Grade Proteinuria (2022) https://acrabstracts.o

Updated on:May 08,2024

Respiratory disease may increase risk for rheumatoid arthritis

(HealthDay)—Respiratory diseases increase the risk for rheumatoid arthritis, according to a study published online Aug. 16 inArthritis & Rheumatology.Vanessa L. Kronzer, M.D., from the Mayo

Updated on: July 02,2024

Respiratory disease may increase risk for rheumatoid arthritis

(HealthDay)—Respiratory diseases increase the risk for rheumatoid arthritis, according to a study published online Aug. 16 inArthritis & Rheumatology.Vanessa L. Kronzer, M.D., from the Mayo

Updated on:July 02,2024

A messenger substance considered to be inflammatory can alleviate asthma symptoms

by Friedrich–Alexander University Erlangen–NurnbergIntranasal rIL-3 application during challenge induces Treg cells. (A) Experimental design for lung ILC2 skewing. (B) After 5 days of in vitro IL

Updated on: May 06,2024

A messenger substance considered to be inflammatory can alleviate asthma symptoms

by Friedrich–Alexander University Erlangen–NurnbergIntranasal rIL-3 application during challenge induces Treg cells. (A) Experimental design for lung ILC2 skewing. (B) After 5 days of in vitro IL

Updated on:May 06,2024

Balance between sleep and exercise may be key to help osteoarthritis patients manage pain

by University of MichiganCredit: CC0 Public DomainIt may shoot through the hands while typing or flare in the knees when getting out of the car. Wherever the pain, over 32 million Americans livin

Updated on: May 08,2024

Balance between sleep and exercise may be key to help osteoarthritis patients manage pain

by University of MichiganCredit: CC0 Public DomainIt may shoot through the hands while typing or flare in the knees when getting out of the car. Wherever the pain, over 32 million Americans livin

Updated on:May 08,2024

Surprise rheumatoid arthritis discovery points to new treatment for joint inflammation

by University of VirginiaCredit: Alexandra Angelich, University CommunicationsResearchers at the University of Virginia School of Medicine have identified an unexpected contributor to rheumatoid

Updated on: June 17,2024

Surprise rheumatoid arthritis discovery points to new treatment for joint inflammation

by University of VirginiaCredit: Alexandra Angelich, University CommunicationsResearchers at the University of Virginia School of Medicine have identified an unexpected contributor to rheumatoid

Updated on:June 17,2024

How gum disease aggravates chronic obstructive pulmonary disease

by American Society for MicrobiologyCredit: CC0 Public DomainSevere gum disease has been linked to the progression of chronic obstructive pulmonary disease, or COPD, but an understanding of how t

Updated on: March 07,2024

How gum disease aggravates chronic obstructive pulmonary disease

by American Society for MicrobiologyCredit: CC0 Public DomainSevere gum disease has been linked to the progression of chronic obstructive pulmonary disease, or COPD, but an understanding of how t

Updated on:March 07,2024

How salt can trigger inflammation in multiple sclerosis

by Bill Hathaway,Yale UniversityCredit: CC0 Public DomainResearchers at Yale have identified a high-salt environment as one of the contributing factors to the development of multiple sclerosis (

Updated on: April 16,2024

How salt can trigger inflammation in multiple sclerosis

by Bill Hathaway,Yale UniversityCredit: CC0 Public DomainResearchers at Yale have identified a high-salt environment as one of the contributing factors to the development of multiple sclerosis (

Updated on:April 16,2024

Increased use of partial knee replacement could save the NHS £30 million per year

by University of OxfordCredit: NDORMSNew research from a randomised clinical trial published today inThe Lancetand funded by the National Institute for Health Research (NIHR) shows th

Updated on: March 28,2024

Increased use of partial knee replacement could save the NHS £30 million per year

by University of OxfordCredit: NDORMSNew research from a randomised clinical trial published today inThe Lancetand funded by the National Institute for Health Research (NIHR) shows th

Updated on:March 28,2024

Pretreatment with TNF inhibitors may improve outcomes of combination cancer immunotherapy

by Universidad de NavarraStudy proposes a new therapeutic approach against cancer that dissociates efficacy and toxicity in the use of combined immunotherapy in animal models. This clinical strat

Updated on: May 08,2024

Pretreatment with TNF inhibitors may improve outcomes of combination cancer immunotherapy

by Universidad de NavarraStudy proposes a new therapeutic approach against cancer that dissociates efficacy and toxicity in the use of combined immunotherapy in animal models. This clinical strat

Updated on:May 08,2024