Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on: May 07,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on:May 07,2024

Low dose steroid use not associated with substantial weight gain or hypertension in patients with rheumatoid arthritis

by American College of PhysiciansCredit: Unsplash/CC0 Public DomainAn analysis of randomized controlled trials has found that the use of low-dose glucocorticoids was not associated with substanti

Updated on: June 17,2024

Low dose steroid use not associated with substantial weight gain or hypertension in patients with rheumatoid arthritis

by American College of PhysiciansCredit: Unsplash/CC0 Public DomainAn analysis of randomized controlled trials has found that the use of low-dose glucocorticoids was not associated with substanti

Updated on:June 17,2024

A messenger substance considered to be inflammatory can alleviate asthma symptoms

by Friedrich–Alexander University Erlangen–NurnbergIntranasal rIL-3 application during challenge induces Treg cells. (A) Experimental design for lung ILC2 skewing. (B) After 5 days of in vitro IL

Updated on: May 06,2024

A messenger substance considered to be inflammatory can alleviate asthma symptoms

by Friedrich–Alexander University Erlangen–NurnbergIntranasal rIL-3 application during challenge induces Treg cells. (A) Experimental design for lung ILC2 skewing. (B) After 5 days of in vitro IL

Updated on:May 06,2024

Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

by Bob Yirka , Medical XpressPerturbation of X-inactivation in immune cells ofFtx−/−females.(A) Map of the X inactivation center showing the location ofXist(green) andFtx

Updated on: May 30,2024

Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

by Bob Yirka , Medical XpressPerturbation of X-inactivation in immune cells ofFtx−/−females.(A) Map of the X inactivation center showing the location ofXist(green) andFtx

Updated on:May 30,2024

Study finds half of patients with low-grade proteinuria develop treatable lupus nephritis within two years

by American College of RheumatologyCredit: Short- and Long-Term Progression of Kidney Involvement in Systemic Lupus Erythematosus Patients with Low-Grade Proteinuria (2022) https://acrabstracts.o

Updated on: May 08,2024

Study finds half of patients with low-grade proteinuria develop treatable lupus nephritis within two years

by American College of RheumatologyCredit: Short- and Long-Term Progression of Kidney Involvement in Systemic Lupus Erythematosus Patients with Low-Grade Proteinuria (2022) https://acrabstracts.o

Updated on:May 08,2024

How gum disease aggravates chronic obstructive pulmonary disease

by American Society for MicrobiologyCredit: CC0 Public DomainSevere gum disease has been linked to the progression of chronic obstructive pulmonary disease, or COPD, but an understanding of how t

Updated on: March 07,2024

How gum disease aggravates chronic obstructive pulmonary disease

by American Society for MicrobiologyCredit: CC0 Public DomainSevere gum disease has been linked to the progression of chronic obstructive pulmonary disease, or COPD, but an understanding of how t

Updated on:March 07,2024

Balance between sleep and exercise may be key to help osteoarthritis patients manage pain

by University of MichiganCredit: CC0 Public DomainIt may shoot through the hands while typing or flare in the knees when getting out of the car. Wherever the pain, over 32 million Americans livin

Updated on: May 08,2024

Balance between sleep and exercise may be key to help osteoarthritis patients manage pain

by University of MichiganCredit: CC0 Public DomainIt may shoot through the hands while typing or flare in the knees when getting out of the car. Wherever the pain, over 32 million Americans livin

Updated on:May 08,2024

Enhanced stability of tristetraprolin found to promote bone health and reduce frailty

by International Association for Dental, Oral, and Craniofacial ResearchCredit: Unsplash/CC0 Public DomainA study used a novel transgenic mouse model (TTP knock-in—TTPKI) that has a moderate elevation

Updated on: March 27,2024

Enhanced stability of tristetraprolin found to promote bone health and reduce frailty

by International Association for Dental, Oral, and Craniofacial ResearchCredit: Unsplash/CC0 Public DomainA study used a novel transgenic mouse model (TTP knock-in—TTPKI) that has a moderate elevation

Updated on:March 27,2024

'New era and treatment of breast cancer': AI is helping detect breast cancer earlier

by Michelle Marchante, Miami HeraldThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by Tom

Updated on: March 13,2024

'New era and treatment of breast cancer': AI is helping detect breast cancer earlier

by Michelle Marchante, Miami HeraldThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by Tom

Updated on:March 13,2024

Increased use of partial knee replacement could save the NHS £30 million per year

by University of OxfordCredit: NDORMSNew research from a randomised clinical trial published today inThe Lancetand funded by the National Institute for Health Research (NIHR) shows th

Updated on: March 28,2024

Increased use of partial knee replacement could save the NHS £30 million per year

by University of OxfordCredit: NDORMSNew research from a randomised clinical trial published today inThe Lancetand funded by the National Institute for Health Research (NIHR) shows th

Updated on:March 28,2024

Surprise rheumatoid arthritis discovery points to new treatment for joint inflammation

by University of VirginiaCredit: Alexandra Angelich, University CommunicationsResearchers at the University of Virginia School of Medicine have identified an unexpected contributor to rheumatoid

Updated on: June 17,2024

Surprise rheumatoid arthritis discovery points to new treatment for joint inflammation

by University of VirginiaCredit: Alexandra Angelich, University CommunicationsResearchers at the University of Virginia School of Medicine have identified an unexpected contributor to rheumatoid

Updated on:June 17,2024

COVID-19, MIS-C and Kawasaki disease share same immune response

by University of California - San DiegoUC San Diego researchers summarize the similarities and differences between COVID-19, MIS-C and Kawasaki disease, three conditions unified by the same immun

Updated on: April 09,2024

COVID-19, MIS-C and Kawasaki disease share same immune response

by University of California - San DiegoUC San Diego researchers summarize the similarities and differences between COVID-19, MIS-C and Kawasaki disease, three conditions unified by the same immun

Updated on:April 09,2024