CAR-T therapy modifications provide new promise for cancer immunotherapies

by King's College LondonCredit: CC0 Public DomainNew research led by Dr. John Maher, from the School of Cancer & Pharmaceutical Sciences, working for Leucid Bio and with biotech company L

Updated on: April 09,2024

CAR-T therapy modifications provide new promise for cancer immunotherapies

by King's College LondonCredit: CC0 Public DomainNew research led by Dr. John Maher, from the School of Cancer & Pharmaceutical Sciences, working for Leucid Bio and with biotech company L

Updated on:April 09,2024

Moderna and Pfizer-BioNTech vaccines prime T cells to fight SARS-CoV-2 variants

by La Jolla Institute for ImmunologyT cells from people who have recovered from COVID-19 or received the Moderna or Pfizer-BioNTech vaccines are still able to recognize several concerning SARS-Co

Updated on: April 20,2024

Moderna and Pfizer-BioNTech vaccines prime T cells to fight SARS-CoV-2 variants

by La Jolla Institute for ImmunologyT cells from people who have recovered from COVID-19 or received the Moderna or Pfizer-BioNTech vaccines are still able to recognize several concerning SARS-Co

Updated on:April 20,2024

Trimethoprim-induced aseptic meningitis described

(HealthDay)—Drug-induced aseptic meningitis following trimethoprim use has been described in a research letter published online Nov. 20 in theInternational Journal of Rheumatic Diseases.Gayathir

Updated on: March 24,2024

Trimethoprim-induced aseptic meningitis described

(HealthDay)—Drug-induced aseptic meningitis following trimethoprim use has been described in a research letter published online Nov. 20 in theInternational Journal of Rheumatic Diseases.Gayathir

Updated on:March 24,2024

Greater support needed to improve the treatment of knee osteoarthritis

by Curtin UniversityCredit: CC0 Public DomainA new Curtin University-led paper has outlined that many people living with knee osteoarthritis may be needlessly suffering or receiving the wrong tre

Updated on: May 23,2024

Greater support needed to improve the treatment of knee osteoarthritis

by Curtin UniversityCredit: CC0 Public DomainA new Curtin University-led paper has outlined that many people living with knee osteoarthritis may be needlessly suffering or receiving the wrong tre

Updated on:May 23,2024

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on: January 11,2025

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on:January 11,2025

Enhanced stability of tristetraprolin found to promote bone health and reduce frailty

by International Association for Dental, Oral, and Craniofacial ResearchCredit: Unsplash/CC0 Public DomainA study used a novel transgenic mouse model (TTP knock-in—TTPKI) that has a moderate elevation

Updated on: March 27,2024

Enhanced stability of tristetraprolin found to promote bone health and reduce frailty

by International Association for Dental, Oral, and Craniofacial ResearchCredit: Unsplash/CC0 Public DomainA study used a novel transgenic mouse model (TTP knock-in—TTPKI) that has a moderate elevation

Updated on:March 27,2024

Some severe COVID-19 cases linked to genetic mutations or antibodies that attack the body

by Howard Hughes Medical InstituteInfection with the novel coronavirus (gold spheres) can cause a range of symptoms. Some people with severe cases of COVID-19 have genetic mutations in key immuni

Updated on: May 08,2024

Some severe COVID-19 cases linked to genetic mutations or antibodies that attack the body

by Howard Hughes Medical InstituteInfection with the novel coronavirus (gold spheres) can cause a range of symptoms. Some people with severe cases of COVID-19 have genetic mutations in key immuni

Updated on:May 08,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on: May 07,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on:May 07,2024

Risk factors ID'd for VTE, ASCVD in rheumatoid arthritis patients

(HealthDay)—For patients with rheumatoid arthritis (RA), there are common risk factors for venous thromboembolism (VTE) and atherosclerotic cardiovascular disease (ASCVD), and the risk for ASCVD is in

Updated on: June 01,2024

Risk factors ID'd for VTE, ASCVD in rheumatoid arthritis patients

(HealthDay)—For patients with rheumatoid arthritis (RA), there are common risk factors for venous thromboembolism (VTE) and atherosclerotic cardiovascular disease (ASCVD), and the risk for ASCVD is in

Updated on:June 01,2024

Pretreatment with TNF inhibitors may improve outcomes of combination cancer immunotherapy

by Universidad de NavarraStudy proposes a new therapeutic approach against cancer that dissociates efficacy and toxicity in the use of combined immunotherapy in animal models. This clinical strat

Updated on: May 08,2024

Pretreatment with TNF inhibitors may improve outcomes of combination cancer immunotherapy

by Universidad de NavarraStudy proposes a new therapeutic approach against cancer that dissociates efficacy and toxicity in the use of combined immunotherapy in animal models. This clinical strat

Updated on:May 08,2024

Potential biomarkers identified for neuropsychiatric symptoms of lupus

by Laurie Fickman,University of HoustonCredit: CC0 Public DomainA globally renowned expert in autoimmune diseases and systemic lupus erythematosus (SLE) at the University of Houston has identifi

Updated on: June 06,2024

Potential biomarkers identified for neuropsychiatric symptoms of lupus

by Laurie Fickman,University of HoustonCredit: CC0 Public DomainA globally renowned expert in autoimmune diseases and systemic lupus erythematosus (SLE) at the University of Houston has identifi

Updated on:June 06,2024

Cell-compressing technique a new path in immunotherapy

by Zach Winn,Massachusetts Institute of TechnologyTo engineer cell functions, SQZ Biotech uses tiny channels on a microfluidic chip to squeeze cells so they can be penetrated by specific molecul

Updated on: April 09,2024

Cell-compressing technique a new path in immunotherapy

by Zach Winn,Massachusetts Institute of TechnologyTo engineer cell functions, SQZ Biotech uses tiny channels on a microfluidic chip to squeeze cells so they can be penetrated by specific molecul

Updated on:April 09,2024