m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on: April 16,2024 11

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on:April 16,2024 11

Detecting arthritis with light

by Fraunhofer-GesellschaftA finger scanner allows doctors to detect arthritis in its early stages. Credit: Fraunhofer IBMT/Bernd MüllerJoint inflammation (arthritis) is a common problem in medica

Updated on: April 07,2024 20

Detecting arthritis with light

by Fraunhofer-GesellschaftA finger scanner allows doctors to detect arthritis in its early stages. Credit: Fraunhofer IBMT/Bernd MüllerJoint inflammation (arthritis) is a common problem in medica

Updated on:April 07,2024 20

Bone drug may be beneficial for knee osteoarthritis

by Boston University School of MedicineCredit: CC0 Public DomainBisphosphonates (a class of drugs that prevent the loss of bone density and used to treat osteoporosis and similar diseases) appear

Updated on: April 17,2024 17

Bone drug may be beneficial for knee osteoarthritis

by Boston University School of MedicineCredit: CC0 Public DomainBisphosphonates (a class of drugs that prevent the loss of bone density and used to treat osteoporosis and similar diseases) appear

Updated on:April 17,2024 17

Epigenetics alters genes in rheumatoid arthritis

by University of California - San DiegoIn this artist's rendering, a DNA molecule is methylated on both strands at the center cytosine. DNA methylation plays an important role in epigenetic g

Updated on: March 24,2024 14

Epigenetics alters genes in rheumatoid arthritis

by University of California - San DiegoIn this artist's rendering, a DNA molecule is methylated on both strands at the center cytosine. DNA methylation plays an important role in epigenetic g

Updated on:March 24,2024 14

GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite

Updated on: April 08,2024 15

GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite

Updated on:April 08,2024 15

Lower RA activity for patients seen at practices with NPs, PAs

(HealthDay)—Patients with rheumatoid arthritis (RA) have lower disease activity when seen at practices with nurse practitioners (NPs) or physician assistants (PAs) versus rheumatologist-only practices

Updated on: March 24,2024 20

Lower RA activity for patients seen at practices with NPs, PAs

(HealthDay)—Patients with rheumatoid arthritis (RA) have lower disease activity when seen at practices with nurse practitioners (NPs) or physician assistants (PAs) versus rheumatologist-only practices

Updated on:March 24,2024 20

A messenger substance considered to be inflammatory can alleviate asthma symptoms

by Friedrich–Alexander University Erlangen–NurnbergIntranasal rIL-3 application during challenge induces Treg cells. (A) Experimental design for lung ILC2 skewing. (B) After 5 days of in vitro IL

Updated on: May 06,2024 11

A messenger substance considered to be inflammatory can alleviate asthma symptoms

by Friedrich–Alexander University Erlangen–NurnbergIntranasal rIL-3 application during challenge induces Treg cells. (A) Experimental design for lung ILC2 skewing. (B) After 5 days of in vitro IL

Updated on:May 06,2024 11

JAK signaling may be behind polymyalgia rheumatica

by Lori SolomonJanus tyrosine kinase (JAK) signaling may be involved in the pathogenesis of polymyalgia rheumatica (PMR), and tofacitinib may be an effective treatment, according to a pilot study publ

Updated on: April 16,2024 18

JAK signaling may be behind polymyalgia rheumatica

by Lori SolomonJanus tyrosine kinase (JAK) signaling may be involved in the pathogenesis of polymyalgia rheumatica (PMR), and tofacitinib may be an effective treatment, according to a pilot study publ

Updated on:April 16,2024 18

Psoriasis patients can get clearer skin with at-home treatment instead of at doctors' offices, study suggests

by Alex Gardner,Perelman School of Medicine at the University of PennsylvaniaCredit: Estzer Miller on PixabayFor decades, people with psoriasis have been treated in clinics with narrowband ultra

Updated on: October 28,2024 0

Psoriasis patients can get clearer skin with at-home treatment instead of at doctors' offices, study suggests

by Alex Gardner,Perelman School of Medicine at the University of PennsylvaniaCredit: Estzer Miller on PixabayFor decades, people with psoriasis have been treated in clinics with narrowband ultra

Updated on:October 28,2024 0

Acoustic technique developed to detect knee osteoarthritis

by Lancaster UniversityA revolutionary medical technique using sound waves to identify osteoarthritis in the knee has been developed by researchers. The UK is leading this new field of&nbsp

Updated on: April 20,2024 15

Acoustic technique developed to detect knee osteoarthritis

by Lancaster UniversityA revolutionary medical technique using sound waves to identify osteoarthritis in the knee has been developed by researchers. The UK is leading this new field of&nbsp

Updated on:April 20,2024 15

Do bacteria in the mouth affect risk of developing rheumatoid arthritis?

by WileyCredit: CC0 Public DomainInvestigators found similarities in the bacterial composition of the mouth among patients with early rheumatoid arthritis and those at risk of developing the dise

Updated on: May 26,2024 4

Do bacteria in the mouth affect risk of developing rheumatoid arthritis?

by WileyCredit: CC0 Public DomainInvestigators found similarities in the bacterial composition of the mouth among patients with early rheumatoid arthritis and those at risk of developing the dise

Updated on:May 26,2024 4

Takayasu arteritis, ulcerative colitis co-occurrence rate high

(HealthDay)—Takayasu arteritis (TAK) has a high rate of co-occurrence and genetic overlap with ulcerative colitis (UC), according to a study published in the August issue ofArthritis & Rheum

Updated on: March 24,2024 20

Takayasu arteritis, ulcerative colitis co-occurrence rate high

(HealthDay)—Takayasu arteritis (TAK) has a high rate of co-occurrence and genetic overlap with ulcerative colitis (UC), according to a study published in the August issue ofArthritis & Rheum

Updated on:March 24,2024 20