Identification of LZTR1 leads to novel insights into RAS-driven diseases

by VIB (the Flanders Institute for Biotechnology)Cancer cell during cell division. Credit: National Institutes of HealthMutations in RAS proteins initiate many of the most aggressive tumors, and

Updated on: April 16,2024 14

Identification of LZTR1 leads to novel insights into RAS-driven diseases

by VIB (the Flanders Institute for Biotechnology)Cancer cell during cell division. Credit: National Institutes of HealthMutations in RAS proteins initiate many of the most aggressive tumors, and

Updated on:April 16,2024 14

A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on: May 07,2024 13

A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on:May 07,2024 13

Uranium exposure tied to lupus

(HealthDay)—High uranium exposure is associated with systemic lupus erythematosus (SLE), according to a study published online Aug. 7 inArthritis & Rheumatology.Pai-Yue Lu-Fritts, M.D., from

Updated on: March 24,2024 18

Uranium exposure tied to lupus

(HealthDay)—High uranium exposure is associated with systemic lupus erythematosus (SLE), according to a study published online Aug. 7 inArthritis & Rheumatology.Pai-Yue Lu-Fritts, M.D., from

Updated on:March 24,2024 18

AI model can quantify radiographic joint damage in rheumatoid arthritis

An international competition resulted in the development of algorithms that provide feasible, quick, and accurate methods to quantify joint damage in rheumatoid arthritis (RA), according to a study pu

Updated on: June 26,2024 6

AI model can quantify radiographic joint damage in rheumatoid arthritis

An international competition resulted in the development of algorithms that provide feasible, quick, and accurate methods to quantify joint damage in rheumatoid arthritis (RA), according to a study pu

Updated on:June 26,2024 6

Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

by Bob Yirka , Medical XpressPerturbation of X-inactivation in immune cells ofFtx−/−females.(A) Map of the X inactivation center showing the location ofXist(green) andFtx

Updated on: May 30,2024 0

Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

by Bob Yirka , Medical XpressPerturbation of X-inactivation in immune cells ofFtx−/−females.(A) Map of the X inactivation center showing the location ofXist(green) andFtx

Updated on:May 30,2024 0

Macrophages produce heat from brown adipose tissue in response to cold, study reveals

by University of TsukubaGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113978Researchers from University of Tsukuba have elucidated the molecular mechanism

Updated on: March 27,2024 0

Macrophages produce heat from brown adipose tissue in response to cold, study reveals

by University of TsukubaGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113978Researchers from University of Tsukuba have elucidated the molecular mechanism

Updated on:March 27,2024 0

A COVID-19 biomarker: Low blood levels of sphingosine predict symptomatic infections

by Medical University of South CarolinaImage of the ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV). Credit: CDCResearchers remain perplexed as to why some patients

Updated on: April 13,2024 13

A COVID-19 biomarker: Low blood levels of sphingosine predict symptomatic infections

by Medical University of South CarolinaImage of the ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV). Credit: CDCResearchers remain perplexed as to why some patients

Updated on:April 13,2024 13

PFAS can suppress white blood cell's ability to destroy invaders

by Tracey Peake,North Carolina State UniversityPFASs used in this study. Names and structures of the PFASs used in this study. Vendors and CAS-RN numbers are provided in Table 1. Chemical struct

Updated on: April 20,2024 17

PFAS can suppress white blood cell's ability to destroy invaders

by Tracey Peake,North Carolina State UniversityPFASs used in this study. Names and structures of the PFASs used in this study. Vendors and CAS-RN numbers are provided in Table 1. Chemical struct

Updated on:April 20,2024 17

Trimethoprim-induced aseptic meningitis described

(HealthDay)—Drug-induced aseptic meningitis following trimethoprim use has been described in a research letter published online Nov. 20 in theInternational Journal of Rheumatic Diseases.Gayathir

Updated on: March 24,2024 12

Trimethoprim-induced aseptic meningitis described

(HealthDay)—Drug-induced aseptic meningitis following trimethoprim use has been described in a research letter published online Nov. 20 in theInternational Journal of Rheumatic Diseases.Gayathir

Updated on:March 24,2024 12

Does an elevated immune response to a gut bacterial protein contribute to rheumatoid arthritis?

by WileyCredit: Unsplash/CC0 Public DomainRheumatoid arthritis is a chronic autoimmune disease that is associated with aberrant immune responses. In a recent analysis published inArthritis

Updated on: June 15,2024 4

Does an elevated immune response to a gut bacterial protein contribute to rheumatoid arthritis?

by WileyCredit: Unsplash/CC0 Public DomainRheumatoid arthritis is a chronic autoimmune disease that is associated with aberrant immune responses. In a recent analysis published inArthritis

Updated on:June 15,2024 4

Study aims to unravel the genetic causes of osteoarthritis

by Wellcome Trust Sanger InstituteA hip with osteoarthritis. In an X-ray of a healthy hip, the heads of the hip bone have smooth, evenly curved surfaces and there is a 'gap' between the h

Updated on: March 28,2024 16

Study aims to unravel the genetic causes of osteoarthritis

by Wellcome Trust Sanger InstituteA hip with osteoarthritis. In an X-ray of a healthy hip, the heads of the hip bone have smooth, evenly curved surfaces and there is a 'gap' between the h

Updated on:March 28,2024 16

Dupilumab cuts exacerbations in late-onset asthma

(HealthDay)—Dupilumab is associated with significantly reduced severe exacerbation rates in patients with late-onset asthma with or without fixed airway obstruction, according to a study presented at

Updated on: April 15,2024 18

Dupilumab cuts exacerbations in late-onset asthma

(HealthDay)—Dupilumab is associated with significantly reduced severe exacerbation rates in patients with late-onset asthma with or without fixed airway obstruction, according to a study presented at

Updated on:April 15,2024 18