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Immunology & Rheumatology
Focuses on rheumatic and immune diseases.
Sub Categories on Immunology & Rheumatology
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Patient-Rated elbow evaluation most responsive instrument

Patient-Rated elbow evaluation most responsive instrument

The Patient-Rated Elbow Evaluation form is the most responsive instrument to identify and quantify elbow joint-specific changes before and after total elbow arthroplasty, according to a study publishe

Patient-Rated elbow evaluation most responsive instrument

The Patient-Rated Elbow Evaluation form is the most responsive instrument to identify and quantify elbow joint-specific changes before and after total elbow arthroplasty, according to a study publishe
GABA released by B-cells blunts the immune response to tumors

GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite

GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite
Evidence for link between 'leaky gut' and autoantibody production in HIV-positive patients

Evidence for link between 'leaky gut' and autoantibody production in HIV-positive patients

by Medical University of South CarolinaHIV-positive, ART-treated patients with high levels of autoantibodies also have increased levels of bacteria (Staphylococcus aureus) products in their blood

Evidence for link between 'leaky gut' and autoantibody production in HIV-positive patients

by Medical University of South CarolinaHIV-positive, ART-treated patients with high levels of autoantibodies also have increased levels of bacteria (Staphylococcus aureus) products in their blood
MyD88—villain of allergies and asthma

MyD88—villain of allergies and asthma

by Lydia Goff ,Duke UniversityFlorescence microscopy image of mouse dendritic cells with mRNA-loaded blood cells.Even if you don't have allergies yourself, I guarantee you can list at

MyD88—villain of allergies and asthma

by Lydia Goff ,Duke UniversityFlorescence microscopy image of mouse dendritic cells with mRNA-loaded blood cells.Even if you don't have allergies yourself, I guarantee you can list at
Upadacitinib beats placebo for psoriatic arthritis

Upadacitinib beats placebo for psoriatic arthritis

For patients with psoriatic arthritis, upadacitinib at a dose of 15 mg or 30 mg once daily is more effective than placebo, according to a study published in the April 1 issue of theNew England J

Upadacitinib beats placebo for psoriatic arthritis

For patients with psoriatic arthritis, upadacitinib at a dose of 15 mg or 30 mg once daily is more effective than placebo, according to a study published in the April 1 issue of theNew England J
New mechanism fueling brain metastasis discovered at Wistar

New mechanism fueling brain metastasis discovered at Wistar

by The Wistar InstituteDr. Qing Chen of The Wistar Institute Credit: The Wistar InstituteScientists at The Wistar Institute described a novel mechanism through which astrocytes, the most abundant

New mechanism fueling brain metastasis discovered at Wistar

by The Wistar InstituteDr. Qing Chen of The Wistar Institute Credit: The Wistar InstituteScientists at The Wistar Institute described a novel mechanism through which astrocytes, the most abundant
Dupilumab cuts exacerbations in late-onset asthma

Dupilumab cuts exacerbations in late-onset asthma

(HealthDay)—Dupilumab is associated with significantly reduced severe exacerbation rates in patients with late-onset asthma with or without fixed airway obstruction, according to a study presented at

Dupilumab cuts exacerbations in late-onset asthma

(HealthDay)—Dupilumab is associated with significantly reduced severe exacerbation rates in patients with late-onset asthma with or without fixed airway obstruction, according to a study presented at
Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to

Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to
Prevalence of multimorbidity up in rheumatoid arthritis

Prevalence of multimorbidity up in rheumatoid arthritis

Patients with rheumatoid arthritis (RA) have an increased prevalence of multimorbidity, according to a study recently published inRMD Open.Cynthia S. Crowson, Ph.D., from the Mayo Clinic in Roch

Prevalence of multimorbidity up in rheumatoid arthritis

Patients with rheumatoid arthritis (RA) have an increased prevalence of multimorbidity, according to a study recently published inRMD Open.Cynthia S. Crowson, Ph.D., from the Mayo Clinic in Roch
CAR T therapy shows long-lasting remissions in non-hodgkin lymphoma

CAR T therapy shows long-lasting remissions in non-hodgkin lymphoma

by Perelman School of Medicine at the University of PennsylvaniaCredit: Unsplash/CC0 Public DomainA significant number of non-Hodgkin lymphoma (NHL) patients in a Penn Medicine-initiated clinical

CAR T therapy shows long-lasting remissions in non-hodgkin lymphoma

by Perelman School of Medicine at the University of PennsylvaniaCredit: Unsplash/CC0 Public DomainA significant number of non-Hodgkin lymphoma (NHL) patients in a Penn Medicine-initiated clinical
Higher incidence of edema with bacteriuria in C1-INH-HAE

Higher incidence of edema with bacteriuria in C1-INH-HAE

(HealthDay)—For patients with hereditary angioedema due to C1-inhibitor deficiency (C1-INH-HAE), those with bacteriuria have a higher number of edematous attacks, according to a study published online

Higher incidence of edema with bacteriuria in C1-INH-HAE

(HealthDay)—For patients with hereditary angioedema due to C1-inhibitor deficiency (C1-INH-HAE), those with bacteriuria have a higher number of edematous attacks, according to a study published online
Researchers discover skin biomarkers in infants that predict early development of food allergies

Researchers discover skin biomarkers in infants that predict early development of food allergies

by National Jewish HealthGraphical abstract. Credit:Journal of Allergy and Clinical Immunology(2024). DOI: 10.1016/j.jaci.2024.02.014Food allergies occur often in childhood and can be

Researchers discover skin biomarkers in infants that predict early development of food allergies

by National Jewish HealthGraphical abstract. Credit:Journal of Allergy and Clinical Immunology(2024). DOI: 10.1016/j.jaci.2024.02.014Food allergies occur often in childhood and can be