Immunology & Rheumatology

A common metabolite may help treat autoimmune diseases

by Hokkaido UniversityIn mice models with adoptive transfer experimental autoimmune encephalomyelitis, treatment with itaconate (right) greatly ameliorates the effects of the disease, compared to

Updated on: May 08,2024

A common metabolite may help treat autoimmune diseases

by Hokkaido UniversityIn mice models with adoptive transfer experimental autoimmune encephalomyelitis, treatment with itaconate (right) greatly ameliorates the effects of the disease, compared to

Updated on:May 08,2024

GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite

Updated on: April 08,2024

GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite

Updated on:April 08,2024

Does body mass index impact pain in individuals with hand osteoarthritis?

by WileyCredit: Unsplash/CC0 Public DomainIn a study inArthritis & Rheumatologyof people with hand osteoarthritis, higher body mass index was associated with greater pain severity

Updated on: June 15,2024

Does body mass index impact pain in individuals with hand osteoarthritis?

by WileyCredit: Unsplash/CC0 Public DomainIn a study inArthritis & Rheumatologyof people with hand osteoarthritis, higher body mass index was associated with greater pain severity

Updated on:June 15,2024

Aerobic exercise may cut fatigue in rheumatoid arthritis

(HealthDay)—Aerobic land-based exercise may be helpful in treating fatigue in patients with rheumatoid arthritis (RA), according to a meta-analysis published in the August issue ofArthritis Care

Updated on: March 24,2024

Aerobic exercise may cut fatigue in rheumatoid arthritis

(HealthDay)—Aerobic land-based exercise may be helpful in treating fatigue in patients with rheumatoid arthritis (RA), according to a meta-analysis published in the August issue ofArthritis Care

Updated on:March 24,2024

Many risk factors contribute to worsening of quality of life in people with knee OA

by University of Eastern FinlandCredit: CC0 Public DomainA new study from the University of Eastern Finland shows that the health-related quality of life of most people who have had or have a hig

Updated on: April 20,2024

Many risk factors contribute to worsening of quality of life in people with knee OA

by University of Eastern FinlandCredit: CC0 Public DomainA new study from the University of Eastern Finland shows that the health-related quality of life of most people who have had or have a hig

Updated on:April 20,2024

Upadacitinib beats placebo for psoriatic arthritis

For patients with psoriatic arthritis, upadacitinib at a dose of 15 mg or 30 mg once daily is more effective than placebo, according to a study published in the April 1 issue of theNew England J

Updated on: May 26,2024

Upadacitinib beats placebo for psoriatic arthritis

For patients with psoriatic arthritis, upadacitinib at a dose of 15 mg or 30 mg once daily is more effective than placebo, according to a study published in the April 1 issue of theNew England J

Updated on:May 26,2024

Program may help patients with rheumatic diseases quit smoking

by WileyCredit: CC0 Public DomainSmoking increases symptoms and health risks for patients with rheumatic diseases, but interventions to help patients quit are rarely available at rheumatology cli

Updated on: March 28,2024

Program may help patients with rheumatic diseases quit smoking

by WileyCredit: CC0 Public DomainSmoking increases symptoms and health risks for patients with rheumatic diseases, but interventions to help patients quit are rarely available at rheumatology cli

Updated on:March 28,2024

Immune receptor provides protective immunity against Group A Streptococcus

by Osaka UniversityFig. 1: The mechanism by which group A Streptococcus (GAS) evades the immune system. The immune receptor Mincle recognizes MGDG, an immunoactivating lipid present on GAS, and t

Updated on: April 16,2024

Immune receptor provides protective immunity against Group A Streptococcus

by Osaka UniversityFig. 1: The mechanism by which group A Streptococcus (GAS) evades the immune system. The immune receptor Mincle recognizes MGDG, an immunoactivating lipid present on GAS, and t

Updated on:April 16,2024

Study: Rheumatoid arthritis plus depression may be deadly

Risk of mood-related mortality greater for men.(HealthDay)—People with rheumatoid arthritis have higher-than-normal rates of depression, which could increase their risk of death, according to a new st

Updated on: March 24,2024

Study: Rheumatoid arthritis plus depression may be deadly

Risk of mood-related mortality greater for men.(HealthDay)—People with rheumatoid arthritis have higher-than-normal rates of depression, which could increase their risk of death, according to a new st

Updated on:March 24,2024

Small molecules induce trained immunity, opening a new approach to fighting disease

by Emily Ayshford,University of ChicagoMyeloid immune cells alongsidered blood cells in an electron micrograph of human blood. Credit: National Cancer InstituteVaccines provide a front-lin

Updated on: July 09,2024

Small molecules induce trained immunity, opening a new approach to fighting disease

by Emily Ayshford,University of ChicagoMyeloid immune cells alongsidered blood cells in an electron micrograph of human blood. Credit: National Cancer InstituteVaccines provide a front-lin

Updated on:July 09,2024

CAR T therapy shows long-lasting remissions in non-hodgkin lymphoma

by Perelman School of Medicine at the University of PennsylvaniaCredit: Unsplash/CC0 Public DomainA significant number of non-Hodgkin lymphoma (NHL) patients in a Penn Medicine-initiated clinical