Upadacitinib beats placebo for psoriatic arthritis

For patients with psoriatic arthritis, upadacitinib at a dose of 15 mg or 30 mg once daily is more effective than placebo, according to a study published in the April 1 issue of theNew England J

Updated on: May 26,2024

Upadacitinib beats placebo for psoriatic arthritis

For patients with psoriatic arthritis, upadacitinib at a dose of 15 mg or 30 mg once daily is more effective than placebo, according to a study published in the April 1 issue of theNew England J

Updated on:May 26,2024

The case of the missing monocyte: Scientists investigate gene that appears to protect against rheumatoid arthritis

by University of North Carolina at Chapel Hill School of MedicineThe hands of a person with arthritis. Image source: NIH.(Medical Xpress) -- An estimated 1.3 million people in the United States s

Updated on: March 24,2024

The case of the missing monocyte: Scientists investigate gene that appears to protect against rheumatoid arthritis

by University of North Carolina at Chapel Hill School of MedicineThe hands of a person with arthritis. Image source: NIH.(Medical Xpress) -- An estimated 1.3 million people in the United States s

Updated on:March 24,2024

Small molecules induce trained immunity, opening a new approach to fighting disease

by Emily Ayshford,University of ChicagoMyeloid immune cells alongsidered blood cells in an electron micrograph of human blood. Credit: National Cancer InstituteVaccines provide a front-lin

Updated on: July 09,2024

Small molecules induce trained immunity, opening a new approach to fighting disease

by Emily Ayshford,University of ChicagoMyeloid immune cells alongsidered blood cells in an electron micrograph of human blood. Credit: National Cancer InstituteVaccines provide a front-lin

Updated on:July 09,2024

Ointment containing DNA molecules can combat allergic contact dermatitis

byUniversity of BonnFluorescence microscopic imaging of the skin treated with the aptamer cream: - The aptamers (here marked in pink) were applied to the top layer of the skin in the form of an

Updated on: July 06,2024

Ointment containing DNA molecules can combat allergic contact dermatitis

byUniversity of BonnFluorescence microscopic imaging of the skin treated with the aptamer cream: - The aptamers (here marked in pink) were applied to the top layer of the skin in the form of an

Updated on:July 06,2024

App to monitor rheumatoid arthritis symptoms does not improve disease outcomes

(HealthDay)—Use of a smartphone application (app) to monitor patient-reported outcomes does not improve satisfaction or disease outcomes in rheumatoid arthritis (RA), but patients are likely to recomm

Updated on: May 29,2024

App to monitor rheumatoid arthritis symptoms does not improve disease outcomes

(HealthDay)—Use of a smartphone application (app) to monitor patient-reported outcomes does not improve satisfaction or disease outcomes in rheumatoid arthritis (RA), but patients are likely to recomm

Updated on:May 29,2024

Study finds holding methotrexate for one week after flu vaccine may be as effective as a two-week hold

by American College of RheumatologyStudy design and vaccine response at 4 and 16 weeks. (A) Study design. (B) The percentage of patients achieving a satisfactory vaccine response, defined as ≥4-f

Updated on: July 02,2024

Study finds holding methotrexate for one week after flu vaccine may be as effective as a two-week hold

by American College of RheumatologyStudy design and vaccine response at 4 and 16 weeks. (A) Study design. (B) The percentage of patients achieving a satisfactory vaccine response, defined as ≥4-f

Updated on:July 02,2024

Recognizing young people's perspectives in inflammatory arthritis

by EULARFigure 1 Example outlining the different steps of the analysis from a meaning unit to lower and higher level concepts. PROMs, patient-reported outcome measures.Inflammatory arthritis is the na

Updated on: May 26,2024

Recognizing young people's perspectives in inflammatory arthritis

by EULARFigure 1 Example outlining the different steps of the analysis from a meaning unit to lower and higher level concepts. PROMs, patient-reported outcome measures.Inflammatory arthritis is the na

Updated on:May 26,2024

Study of infants and young children shows that offspring develop normally in mothers with rheumatic disease

by European League Against Rheumatism (EULAR)Credit: CC0 Public DomainAnkylosing spondylitis (AS) is a complex chronic inflammatory disease of the spine with involvement of the sacroiliac joints. Over

Updated on: June 26,2024

Study of infants and young children shows that offspring develop normally in mothers with rheumatic disease

by European League Against Rheumatism (EULAR)Credit: CC0 Public DomainAnkylosing spondylitis (AS) is a complex chronic inflammatory disease of the spine with involvement of the sacroiliac joints. Over

Updated on:June 26,2024

GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite

Updated on: April 08,2024

GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite

Updated on:April 08,2024

Evidence for link between 'leaky gut' and autoantibody production in HIV-positive patients

by Medical University of South CarolinaHIV-positive, ART-treated patients with high levels of autoantibodies also have increased levels of bacteria (Staphylococcus aureus) products in their blood

Updated on: April 16,2024

Evidence for link between 'leaky gut' and autoantibody production in HIV-positive patients

by Medical University of South CarolinaHIV-positive, ART-treated patients with high levels of autoantibodies also have increased levels of bacteria (Staphylococcus aureus) products in their blood

Updated on:April 16,2024

Investigating healthy lifestyle and mortality in osteoarthritis

by European Alliance of Associations for Rheumatology (EULAR)Credit: CC0 Public DomainHealthy lifestyles are thought to reduce mortality in the general population, but it is not known whether the same

Updated on: April 17,2024

Investigating healthy lifestyle and mortality in osteoarthritis

by European Alliance of Associations for Rheumatology (EULAR)Credit: CC0 Public DomainHealthy lifestyles are thought to reduce mortality in the general population, but it is not known whether the same

Updated on:April 17,2024

High BMI elevates risk of several rheumatic diseases, but not equally for everyone

by Uppsala UniversityCredit: Pixabay/CC0 Public DomainA new study by Uppsala University shows that a higher body mass index (BMI) increases the risk of five different rheumatic diseases: rheumati

Updated on: June 01,2024

High BMI elevates risk of several rheumatic diseases, but not equally for everyone

by Uppsala UniversityCredit: Pixabay/CC0 Public DomainA new study by Uppsala University shows that a higher body mass index (BMI) increases the risk of five different rheumatic diseases: rheumati

Updated on:June 01,2024