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Immunology & Rheumatology
Focuses on rheumatic and immune diseases.
Sub Categories on Immunology & Rheumatology
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Long-term rituximab safe for patients with wegener's

Long-term rituximab safe for patients with wegener's

Repeated and prolonged use of rituximab for B-cell depletion to treat relapses or maintain remission is safe and effective in patients with refractory granulomatosis with polyangiitis (GPA; Wegener&#3

Long-term rituximab safe for patients with wegener's

Repeated and prolonged use of rituximab for B-cell depletion to treat relapses or maintain remission is safe and effective in patients with refractory granulomatosis with polyangiitis (GPA; Wegener&#3
Upadacitinib beats placebo for psoriatic arthritis

Upadacitinib beats placebo for psoriatic arthritis

For patients with psoriatic arthritis, upadacitinib at a dose of 15 mg or 30 mg once daily is more effective than placebo, according to a study published in the April 1 issue of theNew England J

Upadacitinib beats placebo for psoriatic arthritis

For patients with psoriatic arthritis, upadacitinib at a dose of 15 mg or 30 mg once daily is more effective than placebo, according to a study published in the April 1 issue of theNew England J
GABA released by B-cells blunts the immune response to tumors

GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite

GABA released by B-cells blunts the immune response to tumors

by RIKENFig. 1: Metabolic remodeling of immunized LNs and B cell-dependent GABA production. a–e, Mice were injected in the foot pad with OVA + CFA, and iLNs and cLNs were collected for metabolite
Researchers develop a handheld white blood cell tracker

Researchers develop a handheld white blood cell tracker

by Kitta MacPherson,Rutgers UniversityStudy overview. (A) Image of CytoTracker device prototype. (B) An image of the CytoTracker microfluidic impedance cytometer. (C) Schematic of sensing mechan

Researchers develop a handheld white blood cell tracker

by Kitta MacPherson,Rutgers UniversityStudy overview. (A) Image of CytoTracker device prototype. (B) An image of the CytoTracker microfluidic impedance cytometer. (C) Schematic of sensing mechan
Antibodies against phosphorylcholine give protection against rheumatic systemic disease

Antibodies against phosphorylcholine give protection against rheumatic systemic disease

by Karolinska InstitutetCredit: Pixabay/CC0 Public DomainA novel study from the Institute of Environmental Medicine at Karolinska Institutet indicates that antibodies against a small lipid entity

Antibodies against phosphorylcholine give protection against rheumatic systemic disease

by Karolinska InstitutetCredit: Pixabay/CC0 Public DomainA novel study from the Institute of Environmental Medicine at Karolinska Institutet indicates that antibodies against a small lipid entity
Sensors for a 'smart' wound bandage may track healing, immune response

Sensors for a 'smart' wound bandage may track healing, immune response

by Skolkovo Institute of Science and TechnologyCredit: CC0 Public DomainResearchers from Skoltech and the University of Texas at Austin have presented a proof of concept for a wearable sensor tha

Sensors for a 'smart' wound bandage may track healing, immune response

by Skolkovo Institute of Science and TechnologyCredit: CC0 Public DomainResearchers from Skoltech and the University of Texas at Austin have presented a proof of concept for a wearable sensor tha
Expensive arthritis treatment no better than steroid therapy

Expensive arthritis treatment no better than steroid therapy

by Hospital for Special Surgery“On average, each of the therapies resulted in clinically meaningful improvement in pain,” said Lisa Mandl, M.D., MPH, a rheumatologist at Hospital for Special Surg

Expensive arthritis treatment no better than steroid therapy

by Hospital for Special Surgery“On average, each of the therapies resulted in clinically meaningful improvement in pain,” said Lisa Mandl, M.D., MPH, a rheumatologist at Hospital for Special Surg
Could CAR-T cell therapy improve kidney transplants?

Could CAR-T cell therapy improve kidney transplants?

by Susan Buckles, Mayo Clinic News NetworkCredit:Kidney International(2024). DOI: 10.1016/j.kint.2024.02.008Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) could provide a re

Could CAR-T cell therapy improve kidney transplants?

by Susan Buckles, Mayo Clinic News NetworkCredit:Kidney International(2024). DOI: 10.1016/j.kint.2024.02.008Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) could provide a re
Novel checkpoint molecule of natural killer cell anti-tumor immunity revealed

Novel checkpoint molecule of natural killer cell anti-tumor immunity revealed

by Li Yuan,Chinese Academy of SciencesFig. 1. TIPE2 expression correlates with NK cell maturation in both mice and humans.(A) TIPE2 expression of purified splenic NK cells from 2-, 4-, 6-, or 10

Novel checkpoint molecule of natural killer cell anti-tumor immunity revealed

by Li Yuan,Chinese Academy of SciencesFig. 1. TIPE2 expression correlates with NK cell maturation in both mice and humans.(A) TIPE2 expression of purified splenic NK cells from 2-, 4-, 6-, or 10
Early age of menopause linked to seropositivity in RA

Early age of menopause linked to seropositivity in RA

(HealthDay)—In women with early rheumatoid arthritis (RA), early age at menopause is associated with seropositivity, according to a study published in the May issue ofArthritis Care & Resear

Early age of menopause linked to seropositivity in RA

(HealthDay)—In women with early rheumatoid arthritis (RA), early age at menopause is associated with seropositivity, according to a study published in the May issue ofArthritis Care & Resear
Prevalence of gout increases with increasing BMI

Prevalence of gout increases with increasing BMI

Having an increased body mass index correlates with increased prevalence of gout in adults, according to study published online July 6 inArthritis Care & Research.(HealthDay) -- Having an in

Prevalence of gout increases with increasing BMI

Having an increased body mass index correlates with increased prevalence of gout in adults, according to study published online July 6 inArthritis Care & Research.(HealthDay) -- Having an in
VAV1 gene mutations trigger T-cell tumors in mice

VAV1 gene mutations trigger T-cell tumors in mice

by University of TsukubaCredit: CC0 Public DomainLife is an exquisite orchestration of growth and change, with checks and balances that fine-tune complex entwined interactions, both intrinsic and

VAV1 gene mutations trigger T-cell tumors in mice

by University of TsukubaCredit: CC0 Public DomainLife is an exquisite orchestration of growth and change, with checks and balances that fine-tune complex entwined interactions, both intrinsic and