Small molecules induce trained immunity, opening a new approach to fighting disease

by Emily Ayshford,University of ChicagoMyeloid immune cells alongsidered blood cells in an electron micrograph of human blood. Credit: National Cancer InstituteVaccines provide a front-lin

Updated on: July 09,2024

Small molecules induce trained immunity, opening a new approach to fighting disease

by Emily Ayshford,University of ChicagoMyeloid immune cells alongsidered blood cells in an electron micrograph of human blood. Credit: National Cancer InstituteVaccines provide a front-lin

Updated on:July 09,2024

TLK protein inhibition activates the innate immune system

by Institute for Research in Biomedicine - IRBCancer cells with TLK inhibition show replication intermediates (green) at chromosome ends (red). Credit: IRB BarcelonaTousled-like kinases (TLKs) are a p

Updated on: April 24,2024

TLK protein inhibition activates the innate immune system

by Institute for Research in Biomedicine - IRBCancer cells with TLK inhibition show replication intermediates (green) at chromosome ends (red). Credit: IRB BarcelonaTousled-like kinases (TLKs) are a p

Updated on:April 24,2024

Sleep problems not a major issue in rheumatoid arthritis

Sleep problems are not excessive in patients with newly diagnosed rheumatoid arthritis, according to a study recently published inRMD Open.Lauren Lyne, from the Karolinska Institutet in Stockhol

Updated on: May 29,2024

Sleep problems not a major issue in rheumatoid arthritis

Sleep problems are not excessive in patients with newly diagnosed rheumatoid arthritis, according to a study recently published inRMD Open.Lauren Lyne, from the Karolinska Institutet in Stockhol

Updated on:May 29,2024

Air pollution exposure tied to new psoriasis

by Lori SolomonLong-term exposure to air pollution is associated with the development of new psoriasis, according to a studypublishedonline July 16 inJAMA Network Open.Junhui Wu, Ph.

Updated on: July 23,2024

Air pollution exposure tied to new psoriasis

by Lori SolomonLong-term exposure to air pollution is associated with the development of new psoriasis, according to a studypublishedonline July 16 inJAMA Network Open.Junhui Wu, Ph.

Updated on:July 23,2024

How IL-33 plays a key role in enabling the marathon runners of the immune system

by University of BaselGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.01.029When it comes to chronic infections and cancer, a particular type of immune cell play

Updated on: April 16,2024

How IL-33 plays a key role in enabling the marathon runners of the immune system

by University of BaselGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.01.029When it comes to chronic infections and cancer, a particular type of immune cell play

Updated on:April 16,2024

Could CAR-T cell therapy improve kidney transplants?

by Susan Buckles, Mayo Clinic News NetworkCredit:Kidney International(2024). DOI: 10.1016/j.kint.2024.02.008Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) could provide a re

Updated on: April 28,2024

Could CAR-T cell therapy improve kidney transplants?

by Susan Buckles, Mayo Clinic News NetworkCredit:Kidney International(2024). DOI: 10.1016/j.kint.2024.02.008Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) could provide a re

Updated on:April 28,2024

Epigenetics alters genes in rheumatoid arthritis

by University of California - San DiegoIn this artist's rendering, a DNA molecule is methylated on both strands at the center cytosine. DNA methylation plays an important role in epigenetic g

Updated on: March 24,2024

Epigenetics alters genes in rheumatoid arthritis

by University of California - San DiegoIn this artist's rendering, a DNA molecule is methylated on both strands at the center cytosine. DNA methylation plays an important role in epigenetic g

Updated on:March 24,2024

Bone drug may be beneficial for knee osteoarthritis

by Boston University School of MedicineCredit: CC0 Public DomainBisphosphonates (a class of drugs that prevent the loss of bone density and used to treat osteoporosis and similar diseases) appear

Updated on: April 17,2024

Bone drug may be beneficial for knee osteoarthritis

by Boston University School of MedicineCredit: CC0 Public DomainBisphosphonates (a class of drugs that prevent the loss of bone density and used to treat osteoporosis and similar diseases) appear

Updated on:April 17,2024

Antibodies against phosphorylcholine give protection against rheumatic systemic disease

by Karolinska InstitutetCredit: Pixabay/CC0 Public DomainA novel study from the Institute of Environmental Medicine at Karolinska Institutet indicates that antibodies against a small lipid entity

Updated on: May 29,2024

Antibodies against phosphorylcholine give protection against rheumatic systemic disease

by Karolinska InstitutetCredit: Pixabay/CC0 Public DomainA novel study from the Institute of Environmental Medicine at Karolinska Institutet indicates that antibodies against a small lipid entity

Updated on:May 29,2024

Subclinical atherosclerosis noted in diffuse scleroderma

Patients with diffuse systemic sclerosis, without any clinical evidence of cardiovascular disease, have indicators of subclinical atherosclerosis, according to a study published online Aug. 16 in&nbsp

Updated on: March 24,2024

Subclinical atherosclerosis noted in diffuse scleroderma

Patients with diffuse systemic sclerosis, without any clinical evidence of cardiovascular disease, have indicators of subclinical atherosclerosis, according to a study published online Aug. 16 in&nbsp

Updated on:March 24,2024

Rheumatoid arthritis drug not linked to specific birth defects

The rheumatoid arthritis drug leflunomide is not a major cause of birth defects in women who inadvertently become pregnant while taking the drug, although pregnancy should be avoided, according to a s

Updated on: March 24,2024

Rheumatoid arthritis drug not linked to specific birth defects

The rheumatoid arthritis drug leflunomide is not a major cause of birth defects in women who inadvertently become pregnant while taking the drug, although pregnancy should be avoided, according to a s

Updated on:March 24,2024

How gum disease aggravates chronic obstructive pulmonary disease

by American Society for MicrobiologyCredit: CC0 Public DomainSevere gum disease has been linked to the progression of chronic obstructive pulmonary disease, or COPD, but an understanding of how t

Updated on: March 07,2024

How gum disease aggravates chronic obstructive pulmonary disease

by American Society for MicrobiologyCredit: CC0 Public DomainSevere gum disease has been linked to the progression of chronic obstructive pulmonary disease, or COPD, but an understanding of how t

Updated on:March 07,2024