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Immunology & Rheumatology
Focuses on rheumatic and immune diseases.
Sub Categories on Immunology & Rheumatology
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Long-term rituximab safe for patients with wegener's

Long-term rituximab safe for patients with wegener's

Repeated and prolonged use of rituximab for B-cell depletion to treat relapses or maintain remission is safe and effective in patients with refractory granulomatosis with polyangiitis (GPA; Wegener&#3

Long-term rituximab safe for patients with wegener's

Repeated and prolonged use of rituximab for B-cell depletion to treat relapses or maintain remission is safe and effective in patients with refractory granulomatosis with polyangiitis (GPA; Wegener&#3
Novel checkpoint molecule of natural killer cell anti-tumor immunity revealed

Novel checkpoint molecule of natural killer cell anti-tumor immunity revealed

by Li Yuan,Chinese Academy of SciencesFig. 1. TIPE2 expression correlates with NK cell maturation in both mice and humans.(A) TIPE2 expression of purified splenic NK cells from 2-, 4-, 6-, or 10

Novel checkpoint molecule of natural killer cell anti-tumor immunity revealed

by Li Yuan,Chinese Academy of SciencesFig. 1. TIPE2 expression correlates with NK cell maturation in both mice and humans.(A) TIPE2 expression of purified splenic NK cells from 2-, 4-, 6-, or 10
Rheumatoid arthritis drug not linked to specific birth defects

Rheumatoid arthritis drug not linked to specific birth defects

The rheumatoid arthritis drug leflunomide is not a major cause of birth defects in women who inadvertently become pregnant while taking the drug, although pregnancy should be avoided, according to a s

Rheumatoid arthritis drug not linked to specific birth defects

The rheumatoid arthritis drug leflunomide is not a major cause of birth defects in women who inadvertently become pregnant while taking the drug, although pregnancy should be avoided, according to a s
Scientists identify reversible molecular defect underlying rheumatoid arthritis

Scientists identify reversible molecular defect underlying rheumatoid arthritis

by Bruce Goldman,Stanford University Medical CenterScanning electron micrograph of human T lymphocyte or T cell. Credit: NIAID/NIHIn rheumatoid arthritis, immune cells called helper T cells beha

Scientists identify reversible molecular defect underlying rheumatoid arthritis

by Bruce Goldman,Stanford University Medical CenterScanning electron micrograph of human T lymphocyte or T cell. Credit: NIAID/NIHIn rheumatoid arthritis, immune cells called helper T cells beha
Many risk factors contribute to worsening of quality of life in people with knee OA

Many risk factors contribute to worsening of quality of life in people with knee OA

by University of Eastern FinlandCredit: CC0 Public DomainA new study from the University of Eastern Finland shows that the health-related quality of life of most people who have had or have a hig

Many risk factors contribute to worsening of quality of life in people with knee OA

by University of Eastern FinlandCredit: CC0 Public DomainA new study from the University of Eastern Finland shows that the health-related quality of life of most people who have had or have a hig
A COVID-19 biomarker: Low blood levels of sphingosine predict symptomatic infections

A COVID-19 biomarker: Low blood levels of sphingosine predict symptomatic infections

by Medical University of South CarolinaImage of the ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV). Credit: CDCResearchers remain perplexed as to why some patients

A COVID-19 biomarker: Low blood levels of sphingosine predict symptomatic infections

by Medical University of South CarolinaImage of the ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV). Credit: CDCResearchers remain perplexed as to why some patients
Early knee arthritis symptoms first felt when using stairs

Early knee arthritis symptoms first felt when using stairs

by University of LeedsPeople who suffer from knee pain when using the stairs may be experiencing the early symptoms of osteoarthritis, according to a new University of Leeds study.The research, p

Early knee arthritis symptoms first felt when using stairs

by University of LeedsPeople who suffer from knee pain when using the stairs may be experiencing the early symptoms of osteoarthritis, according to a new University of Leeds study.The research, p
A new open-access portal for human immunology data and tools

A new open-access portal for human immunology data and tools

by Rachel Tompa,Allen Institute for Brain ScienceTEA-seq single panel cell type data from Human Immune System Explorer. Credit: Zach Thomson/Allen InstituteResearchers at the Allen Institute for

A new open-access portal for human immunology data and tools

by Rachel Tompa,Allen Institute for Brain ScienceTEA-seq single panel cell type data from Human Immune System Explorer. Credit: Zach Thomson/Allen InstituteResearchers at the Allen Institute for
COVID-19: Biomarkers linked to severe forms of the disease

COVID-19: Biomarkers linked to severe forms of the disease

by University of MontrealColorized scanning electron micrograph of an apoptotic cell (green) heavily infected with SARS-COV-2 virus particles (yellow), isolated from a patient sample. Image captu

COVID-19: Biomarkers linked to severe forms of the disease

by University of MontrealColorized scanning electron micrograph of an apoptotic cell (green) heavily infected with SARS-COV-2 virus particles (yellow), isolated from a patient sample. Image captu
Could CAR-T cell therapy improve kidney transplants?

Could CAR-T cell therapy improve kidney transplants?

by Susan Buckles, Mayo Clinic News NetworkCredit:Kidney International(2024). DOI: 10.1016/j.kint.2024.02.008Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) could provide a re

Could CAR-T cell therapy improve kidney transplants?

by Susan Buckles, Mayo Clinic News NetworkCredit:Kidney International(2024). DOI: 10.1016/j.kint.2024.02.008Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) could provide a re
Balance between sleep and exercise may be key to help osteoarthritis patients manage pain

Balance between sleep and exercise may be key to help osteoarthritis patients manage pain

by University of MichiganCredit: CC0 Public DomainIt may shoot through the hands while typing or flare in the knees when getting out of the car. Wherever the pain, over 32 million Americans livin

Balance between sleep and exercise may be key to help osteoarthritis patients manage pain

by University of MichiganCredit: CC0 Public DomainIt may shoot through the hands while typing or flare in the knees when getting out of the car. Wherever the pain, over 32 million Americans livin
Macrophages produce heat from brown adipose tissue in response to cold, study reveals

Macrophages produce heat from brown adipose tissue in response to cold, study reveals

by University of TsukubaGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113978Researchers from University of Tsukuba have elucidated the molecular mechanism

Macrophages produce heat from brown adipose tissue in response to cold, study reveals

by University of TsukubaGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113978Researchers from University of Tsukuba have elucidated the molecular mechanism