Research unveils metabolic strategies to enhance CAR-T cell therapy

by Cactus CommunicationsChimeric antigen receptor T (CAR-T) cell therapy effectively treats hematological tumors but struggles due to metabolic challenges in the tumor microenvironment. Tumor cells di

Updated on: March 27,2024

Research unveils metabolic strategies to enhance CAR-T cell therapy

by Cactus CommunicationsChimeric antigen receptor T (CAR-T) cell therapy effectively treats hematological tumors but struggles due to metabolic challenges in the tumor microenvironment. Tumor cells di

Updated on:March 27,2024

Evidence for link between 'leaky gut' and autoantibody production in HIV-positive patients

by Medical University of South CarolinaHIV-positive, ART-treated patients with high levels of autoantibodies also have increased levels of bacteria (Staphylococcus aureus) products in their blood

Updated on: April 16,2024

Evidence for link between 'leaky gut' and autoantibody production in HIV-positive patients

by Medical University of South CarolinaHIV-positive, ART-treated patients with high levels of autoantibodies also have increased levels of bacteria (Staphylococcus aureus) products in their blood

Updated on:April 16,2024

How does vaccination thwart pneumococcal infection? Animal model uncovers 'capture and kill' scenario

by Delthia Ricks , Medical XpressRepresentative IVM imaging of vaccine-activated capture of ST865 pneumococci in the liver sinusoids. Pneumococci, green; KCs, red; ECs, cyan; neutrophils, magenta. Cre

Updated on: March 07,2024

How does vaccination thwart pneumococcal infection? Animal model uncovers 'capture and kill' scenario

by Delthia Ricks , Medical XpressRepresentative IVM imaging of vaccine-activated capture of ST865 pneumococci in the liver sinusoids. Pneumococci, green; KCs, red; ECs, cyan; neutrophils, magenta. Cre

Updated on:March 07,2024

PFAS can suppress white blood cell's ability to destroy invaders

by Tracey Peake,North Carolina State UniversityPFASs used in this study. Names and structures of the PFASs used in this study. Vendors and CAS-RN numbers are provided in Table 1. Chemical struct

Updated on: April 20,2024

PFAS can suppress white blood cell's ability to destroy invaders

by Tracey Peake,North Carolina State UniversityPFASs used in this study. Names and structures of the PFASs used in this study. Vendors and CAS-RN numbers are provided in Table 1. Chemical struct

Updated on:April 20,2024

Researchers discover potential new approach to treating psoriatic joint inflammation

by UC DavisCredit: CC0 Public DomainAn international team of researchers, led by UC Davis Health, has developed a new therapeutic approach to treating psoriatic arthritis, a chronic inflammatory

Updated on: June 17,2024

Researchers discover potential new approach to treating psoriatic joint inflammation

by UC DavisCredit: CC0 Public DomainAn international team of researchers, led by UC Davis Health, has developed a new therapeutic approach to treating psoriatic arthritis, a chronic inflammatory

Updated on:June 17,2024

New safety checklist aims to prevent side effects in patients with arthritis

by Line Rønn,Aarhus UniversityOverview of contraindications and warnings from EMA SmPC and FDA PI for biologic and targeted synthetic disease modifying antirheumatic drugs based on MedDRA system

Updated on: August 08,2024

New safety checklist aims to prevent side effects in patients with arthritis

by Line Rønn,Aarhus UniversityOverview of contraindications and warnings from EMA SmPC and FDA PI for biologic and targeted synthetic disease modifying antirheumatic drugs based on MedDRA system

Updated on:August 08,2024

COVID-19 model reveals key role for innate immunity in controlling viral load

by American Chemical SocietyColorized scanning electron micrograph of a cell (blue) heavily infected with SARS-CoV-2 virus particles (red), isolated from a patient sample. Image captured at the N

Updated on: April 10,2024

COVID-19 model reveals key role for innate immunity in controlling viral load

by American Chemical SocietyColorized scanning electron micrograph of a cell (blue) heavily infected with SARS-CoV-2 virus particles (red), isolated from a patient sample. Image captured at the N

Updated on:April 10,2024

Meta-analysis quantifies lifestyle factors accounting for RA incidence

(HealthDay)—Nearly one-third of rheumatoid arthritis (RA) incidence is attributed to smoking, excess body mass index, and low alcohol consumption, according to a study published online Jan. 26 in&nbsp

Updated on: May 08,2024

Meta-analysis quantifies lifestyle factors accounting for RA incidence

(HealthDay)—Nearly one-third of rheumatoid arthritis (RA) incidence is attributed to smoking, excess body mass index, and low alcohol consumption, according to a study published online Jan. 26 in&nbsp

Updated on:May 08,2024

Study of infants and young children shows that offspring develop normally in mothers with rheumatic disease

by European League Against Rheumatism (EULAR)Credit: CC0 Public DomainAnkylosing spondylitis (AS) is a complex chronic inflammatory disease of the spine with involvement of the sacroiliac joints. Over

Updated on: June 26,2024

Study of infants and young children shows that offspring develop normally in mothers with rheumatic disease

by European League Against Rheumatism (EULAR)Credit: CC0 Public DomainAnkylosing spondylitis (AS) is a complex chronic inflammatory disease of the spine with involvement of the sacroiliac joints. Over

Updated on:June 26,2024

B cells linked to immunotherapy for melanoma

by European Molecular Biology LaboratoryUsing multiplex-immunostaining to characterise B cells. Credit: Christine WagnerResearchers at EMBL's European Bioinformatics Institute and the Medical

Updated on: April 08,2024

B cells linked to immunotherapy for melanoma

by European Molecular Biology LaboratoryUsing multiplex-immunostaining to characterise B cells. Credit: Christine WagnerResearchers at EMBL's European Bioinformatics Institute and the Medical

Updated on:April 08,2024

FDA approves first interchangeable biosimilar for inflammatory diseases

(HealthDay)—The first interchangeable biosimilar product to Humira (adalimumab) was approved by the U.S. Food and Drug Administration on Oct. 15, the agency announced Monday.Cyltezo (adalimumab-adbm),

Updated on: June 17,2024

FDA approves first interchangeable biosimilar for inflammatory diseases

(HealthDay)—The first interchangeable biosimilar product to Humira (adalimumab) was approved by the U.S. Food and Drug Administration on Oct. 15, the agency announced Monday.Cyltezo (adalimumab-adbm),

Updated on:June 17,2024

Arthritis sufferers excluded from everyday life

by Fran Strachan,University of New South WalesCredit: ThinkstockArthritis is the second leading cause of disability in Australia with many sufferers so severely disabled they cannot engage in ba

Updated on: March 24,2024

Arthritis sufferers excluded from everyday life

by Fran Strachan,University of New South WalesCredit: ThinkstockArthritis is the second leading cause of disability in Australia with many sufferers so severely disabled they cannot engage in ba

Updated on:March 24,2024