PFAS can suppress white blood cell's ability to destroy invaders

by Tracey Peake,North Carolina State UniversityPFASs used in this study. Names and structures of the PFASs used in this study. Vendors and CAS-RN numbers are provided in Table 1. Chemical struct

Updated on: April 20,2024 17

PFAS can suppress white blood cell's ability to destroy invaders

by Tracey Peake,North Carolina State UniversityPFASs used in this study. Names and structures of the PFASs used in this study. Vendors and CAS-RN numbers are provided in Table 1. Chemical struct

Updated on:April 20,2024 17

New study points to a better way to ward off asthma triggers

by La Jolla Institute for ImmunologyLeft: Lung tissue of untreated mice. Right: Lung tissue of mice treated with antibodies blocking OX40L and CD30L. Credit: Dr. Gurupreet Sethi, La Jolla Institu

Updated on: May 05,2024 19

New study points to a better way to ward off asthma triggers

by La Jolla Institute for ImmunologyLeft: Lung tissue of untreated mice. Right: Lung tissue of mice treated with antibodies blocking OX40L and CD30L. Credit: Dr. Gurupreet Sethi, La Jolla Institu

Updated on:May 05,2024 19

Detecting arthritis with light

by Fraunhofer-GesellschaftA finger scanner allows doctors to detect arthritis in its early stages. Credit: Fraunhofer IBMT/Bernd MüllerJoint inflammation (arthritis) is a common problem in medica

Updated on: April 07,2024 20

Detecting arthritis with light

by Fraunhofer-GesellschaftA finger scanner allows doctors to detect arthritis in its early stages. Credit: Fraunhofer IBMT/Bernd MüllerJoint inflammation (arthritis) is a common problem in medica

Updated on:April 07,2024 20

Expensive arthritis treatment no better than steroid therapy

by Hospital for Special Surgery“On average, each of the therapies resulted in clinically meaningful improvement in pain,” said Lisa Mandl, M.D., MPH, a rheumatologist at Hospital for Special Surg

Updated on: March 24,2024 10

Expensive arthritis treatment no better than steroid therapy

by Hospital for Special Surgery“On average, each of the therapies resulted in clinically meaningful improvement in pain,” said Lisa Mandl, M.D., MPH, a rheumatologist at Hospital for Special Surg

Updated on:March 24,2024 10

Anti-cancer virus fits tumor receptor like a 'key in a lock'

by Okinawa Institute of Science and TechnologyA cryo-EM map of the receptor decorated capsid in which a single protomer was replaced with the atomic model. Seneca Valley Virus capsid proteins are

Updated on: April 08,2024 18

Anti-cancer virus fits tumor receptor like a 'key in a lock'

by Okinawa Institute of Science and TechnologyA cryo-EM map of the receptor decorated capsid in which a single protomer was replaced with the atomic model. Seneca Valley Virus capsid proteins are

Updated on:April 08,2024 18

COVID-19 model reveals key role for innate immunity in controlling viral load

by American Chemical SocietyColorized scanning electron micrograph of a cell (blue) heavily infected with SARS-CoV-2 virus particles (red), isolated from a patient sample. Image captured at the N

Updated on: April 10,2024 19

COVID-19 model reveals key role for innate immunity in controlling viral load

by American Chemical SocietyColorized scanning electron micrograph of a cell (blue) heavily infected with SARS-CoV-2 virus particles (red), isolated from a patient sample. Image captured at the N

Updated on:April 10,2024 19

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on: April 16,2024 11

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on:April 16,2024 11

Fatigue common even with early rheumatoid arthritis

(HealthDay)—Fatigue is prevalent and persistent in early rheumatoid arthritis (RA), according to a study published online Dec. 27 inRheumatology.Onosi Sylvia Ifesemen, M.B.B.S., from the Univers

Updated on: June 17,2024 3

Fatigue common even with early rheumatoid arthritis

(HealthDay)—Fatigue is prevalent and persistent in early rheumatoid arthritis (RA), according to a study published online Dec. 27 inRheumatology.Onosi Sylvia Ifesemen, M.B.B.S., from the Univers

Updated on:June 17,2024 3

Survival improving after hip and knee replacement

(HealthDay)—Short-term survival after elective total hip (THR) and total knee replacement (TKR) has greatly improved since the early 1990s, even though comorbidities have increased, according to a stu

Updated on: April 08,2024 14

Survival improving after hip and knee replacement

(HealthDay)—Short-term survival after elective total hip (THR) and total knee replacement (TKR) has greatly improved since the early 1990s, even though comorbidities have increased, according to a stu

Updated on:April 08,2024 14

Old immune systems revitalized in mouse study, may improve vaccine response in the elderly

byStanford University Medical CenterCredit: CC0 Public DomainPlanes, trains, boats, automobiles and even feet. During the past decades and centuries, global travel and human migration have made

Updated on: March 30,2024 6

Old immune systems revitalized in mouse study, may improve vaccine response in the elderly

byStanford University Medical CenterCredit: CC0 Public DomainPlanes, trains, boats, automobiles and even feet. During the past decades and centuries, global travel and human migration have made

Updated on:March 30,2024 6

Continuation vs. discontinuation of bDMARDs during the perioperative period

by Wolters Kluwer HealthCredit: Pixabay/CC0 Public DomainFor patients with rheumatic arthritis and other chronic inflammatory diseases, discontinuing biologic disease-modifying anti-rheumatic dru

Updated on: June 26,2024 4

Continuation vs. discontinuation of bDMARDs during the perioperative period

by Wolters Kluwer HealthCredit: Pixabay/CC0 Public DomainFor patients with rheumatic arthritis and other chronic inflammatory diseases, discontinuing biologic disease-modifying anti-rheumatic dru

Updated on:June 26,2024 4

The case of the missing monocyte: Scientists investigate gene that appears to protect against rheumatoid arthritis

by University of North Carolina at Chapel Hill School of MedicineThe hands of a person with arthritis. Image source: NIH.(Medical Xpress) -- An estimated 1.3 million people in the United States s

Updated on: March 24,2024 16

The case of the missing monocyte: Scientists investigate gene that appears to protect against rheumatoid arthritis

by University of North Carolina at Chapel Hill School of MedicineThe hands of a person with arthritis. Image source: NIH.(Medical Xpress) -- An estimated 1.3 million people in the United States s

Updated on:March 24,2024 16