Methotrexate improves function in people with knee OA after three months

by American College of RheumatologyCredit: CC0 Public DomainA new study presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that after three months of t

Updated on: May 13,2024

Methotrexate improves function in people with knee OA after three months

by American College of RheumatologyCredit: CC0 Public DomainA new study presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that after three months of t

Updated on:May 13,2024

New class of molecules play key role in influencing the immune system

by Brigham and Women's HospitalProresolving lipid mediators – resolvin D1 (RvD1), resolvin D2 (RvD2), and maresin 1 (MaR1) – modulate T cell responses. Credit: Valerio Chiurchiu et al., Scien

Updated on: May 05,2024

New class of molecules play key role in influencing the immune system

by Brigham and Women's HospitalProresolving lipid mediators – resolvin D1 (RvD1), resolvin D2 (RvD2), and maresin 1 (MaR1) – modulate T cell responses. Credit: Valerio Chiurchiu et al., Scien

Updated on:May 05,2024

How does vaccination thwart pneumococcal infection? Animal model uncovers 'capture and kill' scenario

by Delthia Ricks , Medical XpressRepresentative IVM imaging of vaccine-activated capture of ST865 pneumococci in the liver sinusoids. Pneumococci, green; KCs, red; ECs, cyan; neutrophils, magenta. Cre

Updated on: March 07,2024

How does vaccination thwart pneumococcal infection? Animal model uncovers 'capture and kill' scenario

by Delthia Ricks , Medical XpressRepresentative IVM imaging of vaccine-activated capture of ST865 pneumococci in the liver sinusoids. Pneumococci, green; KCs, red; ECs, cyan; neutrophils, magenta. Cre

Updated on:March 07,2024

Rheumatoid arthritis drug not linked to specific birth defects

The rheumatoid arthritis drug leflunomide is not a major cause of birth defects in women who inadvertently become pregnant while taking the drug, although pregnancy should be avoided, according to a s

Updated on: March 24,2024

Rheumatoid arthritis drug not linked to specific birth defects

The rheumatoid arthritis drug leflunomide is not a major cause of birth defects in women who inadvertently become pregnant while taking the drug, although pregnancy should be avoided, according to a s

Updated on:March 24,2024

Brain activity linked to TNF inhibitor response in RA

Patients with rheumatoid arthritis who respond to tumor necrosis factor inhibitors show changes in activity in pain-related areas of the brain before clinical signs of improvement are observed, accord

Updated on: April 08,2024

Brain activity linked to TNF inhibitor response in RA

Patients with rheumatoid arthritis who respond to tumor necrosis factor inhibitors show changes in activity in pain-related areas of the brain before clinical signs of improvement are observed, accord

Updated on:April 08,2024

Cell adaptation in critically ill could be difference between life and death, new study shows

by Amy King,University of PlymouthGraphical abstract. Credit:Redox Biology(2021). DOI: 10.1016/j.redox.2021.101907Creating the best conditions for cells to make energy and survive cr

Updated on: May 06,2024

Cell adaptation in critically ill could be difference between life and death, new study shows

by Amy King,University of PlymouthGraphical abstract. Credit:Redox Biology(2021). DOI: 10.1016/j.redox.2021.101907Creating the best conditions for cells to make energy and survive cr

Updated on:May 06,2024

New vaccine protects from widespread, costly infection, mice study shows

by American Society for MicrobiologyCredit: CC0 Public DomainA newly developed experimental vaccine was more than eighty percent effective in protecting mice from succumbing toStaphylococcu

Updated on: May 08,2024

New vaccine protects from widespread, costly infection, mice study shows

by American Society for MicrobiologyCredit: CC0 Public DomainA newly developed experimental vaccine was more than eighty percent effective in protecting mice from succumbing toStaphylococcu

Updated on:May 08,2024

TAp63: A new protein drug target for rheumatoid arthritis

by Chiba UniversityGraphical abstract. Credit:JCI Insight(2023). DOI: 10.1172/jci.insight.164778Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The

Updated on: May 08,2024

TAp63: A new protein drug target for rheumatoid arthritis

by Chiba UniversityGraphical abstract. Credit:JCI Insight(2023). DOI: 10.1172/jci.insight.164778Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The

Updated on:May 08,2024

Boosting CAR-T cell therapies from under the skin

by Benjamin Boettner,Harvard UniversityT-cell enhancing scaffolds can be locally injected under the skin following CAR-T cell therapy, and allowcirculating CAR-T cells to infiltrate their 3-dime

Updated on: June 15,2024

Boosting CAR-T cell therapies from under the skin

by Benjamin Boettner,Harvard UniversityT-cell enhancing scaffolds can be locally injected under the skin following CAR-T cell therapy, and allowcirculating CAR-T cells to infiltrate their 3-dime

Updated on:June 15,2024

Sharing of skin microbiome between children with atopic dermatitis and healthy contacts might contribute to recurrence

by National University of SingaporeGraphical abstract. Credit:Journal of Allergy and Clinical Immunology(2022). DOI: 10.1016/j.jaci.2022.01.031Patients with moderate to severe atopic

Updated on: June 12,2024

Sharing of skin microbiome between children with atopic dermatitis and healthy contacts might contribute to recurrence

by National University of SingaporeGraphical abstract. Credit:Journal of Allergy and Clinical Immunology(2022). DOI: 10.1016/j.jaci.2022.01.031Patients with moderate to severe atopic

Updated on:June 12,2024

Does an elevated immune response to a gut bacterial protein contribute to rheumatoid arthritis?

by WileyCredit: Unsplash/CC0 Public DomainRheumatoid arthritis is a chronic autoimmune disease that is associated with aberrant immune responses. In a recent analysis published inArthritis

Updated on: June 15,2024

Does an elevated immune response to a gut bacterial protein contribute to rheumatoid arthritis?

by WileyCredit: Unsplash/CC0 Public DomainRheumatoid arthritis is a chronic autoimmune disease that is associated with aberrant immune responses. In a recent analysis published inArthritis

Updated on:June 15,2024

Vitamin D shows no impact on interferon response in SLE

(HealthDay)—For patients with systemic lupus erythematosus (SLE), vitamin D3supplementation does not affect interferon (IFN) signature, according to a study published in the July issue ofA

Updated on: April 08,2024

Vitamin D shows no impact on interferon response in SLE

(HealthDay)—For patients with systemic lupus erythematosus (SLE), vitamin D3supplementation does not affect interferon (IFN) signature, according to a study published in the July issue ofA

Updated on:April 08,2024