CAR T cells suppress GI solid tumor cells, without toxicity to healthy tissue, in preclinical research

by University of PennsylvaniaCDH17 CARTs attack tumor but spare normal tissue. Credit: Penn MedicineChimeric antigen receptor (CAR) T cells can be remarkably effective in treating leukemias and l

Updated on: April 09,2024

CAR T cells suppress GI solid tumor cells, without toxicity to healthy tissue, in preclinical research

by University of PennsylvaniaCDH17 CARTs attack tumor but spare normal tissue. Credit: Penn MedicineChimeric antigen receptor (CAR) T cells can be remarkably effective in treating leukemias and l

Updated on:April 09,2024

By better predicting asthma risk, preventive treatments could bypass disease development

by University of ArizonaRespiratory virus prevalence, baseline CBMC cell proportions, multi-omic data set overview. (A) Bar plot of viral agents detected from infectious NPAs taken during year on

Updated on: June 12,2024

By better predicting asthma risk, preventive treatments could bypass disease development

by University of ArizonaRespiratory virus prevalence, baseline CBMC cell proportions, multi-omic data set overview. (A) Bar plot of viral agents detected from infectious NPAs taken during year on

Updated on:June 12,2024

Study of infants and young children shows that offspring develop normally in mothers with rheumatic disease

by European League Against Rheumatism (EULAR)Credit: CC0 Public DomainAnkylosing spondylitis (AS) is a complex chronic inflammatory disease of the spine with involvement of the sacroiliac joints. Over

Updated on: June 26,2024

Study of infants and young children shows that offspring develop normally in mothers with rheumatic disease

by European League Against Rheumatism (EULAR)Credit: CC0 Public DomainAnkylosing spondylitis (AS) is a complex chronic inflammatory disease of the spine with involvement of the sacroiliac joints. Over

Updated on:June 26,2024

NSAIDs may worsen arthritis inflammation

by Radiological Society of North AmericaThe fat pad adjacent to the kneecap (Hoffa's fat pad, infrapatellar fat pad) can change in signal on MRI when the knee is inflamed. (A) Normal knee wit

Updated on: June 26,2024

NSAIDs may worsen arthritis inflammation

by Radiological Society of North AmericaThe fat pad adjacent to the kneecap (Hoffa's fat pad, infrapatellar fat pad) can change in signal on MRI when the knee is inflamed. (A) Normal knee wit

Updated on:June 26,2024

Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to

Updated on: September 07,2024

Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to

Updated on:September 07,2024

TNF inhibitors may not modify polyarticular JIA disease process

(HealthDay)—For children with polyarticular juvenile idiopathic arthritis (JIA), discontinuing medications is challenging, with high relapse rates, especially after discontinuation of tumor necrosis f

Updated on: April 08,2024

TNF inhibitors may not modify polyarticular JIA disease process

(HealthDay)—For children with polyarticular juvenile idiopathic arthritis (JIA), discontinuing medications is challenging, with high relapse rates, especially after discontinuation of tumor necrosis f

Updated on:April 08,2024

Patient-Rated elbow evaluation most responsive instrument

The Patient-Rated Elbow Evaluation form is the most responsive instrument to identify and quantify elbow joint-specific changes before and after total elbow arthroplasty, according to a study publishe

Updated on: April 08,2024

Patient-Rated elbow evaluation most responsive instrument

The Patient-Rated Elbow Evaluation form is the most responsive instrument to identify and quantify elbow joint-specific changes before and after total elbow arthroplasty, according to a study publishe

Updated on:April 08,2024

Small molecules induce trained immunity, opening a new approach to fighting disease

by Emily Ayshford,University of ChicagoMyeloid immune cells alongsidered blood cells in an electron micrograph of human blood. Credit: National Cancer InstituteVaccines provide a front-lin

Updated on: July 09,2024

Small molecules induce trained immunity, opening a new approach to fighting disease

by Emily Ayshford,University of ChicagoMyeloid immune cells alongsidered blood cells in an electron micrograph of human blood. Credit: National Cancer InstituteVaccines provide a front-lin

Updated on:July 09,2024

Socioeconomic factors linked to persistently active rheumatoid arthritis

by Elana GotkineSocioeconomic factors and deprivation are associated with persistently active rheumatoid arthritis (pactiveRA), according to a study published online July 14 inRMD Open.Maryam Ad

Updated on: July 23,2024

Socioeconomic factors linked to persistently active rheumatoid arthritis

by Elana GotkineSocioeconomic factors and deprivation are associated with persistently active rheumatoid arthritis (pactiveRA), according to a study published online July 14 inRMD Open.Maryam Ad

Updated on:July 23,2024

Arthritis reported by almost one in four U.S. adults

(HealthDay)—Almost one-quarter of U.S. adults report arthritis, according to research published in the Oct. 8 issue of the U.S. Centers for Disease Control and PreventionMorbidity and Mortality

Updated on: May 08,2024

Arthritis reported by almost one in four U.S. adults

(HealthDay)—Almost one-quarter of U.S. adults report arthritis, according to research published in the Oct. 8 issue of the U.S. Centers for Disease Control and PreventionMorbidity and Mortality

Updated on:May 08,2024

New study questions the efficacy of many osteoarthritis treatments

by Lund UniversityCredit: Pixabay/CC0 Public DomainRecruiting osteoarthritis patients with a lot of pain to clinical studies may give incorrect results if the researcher does not account for the

Updated on: May 26,2024

New study questions the efficacy of many osteoarthritis treatments

by Lund UniversityCredit: Pixabay/CC0 Public DomainRecruiting osteoarthritis patients with a lot of pain to clinical studies may give incorrect results if the researcher does not account for the

Updated on:May 26,2024

Prevalence of multimorbidity up in rheumatoid arthritis

Patients with rheumatoid arthritis (RA) have an increased prevalence of multimorbidity, according to a study recently published inRMD Open.Cynthia S. Crowson, Ph.D., from the Mayo Clinic in Roch

Updated on: June 17,2024

Prevalence of multimorbidity up in rheumatoid arthritis

Patients with rheumatoid arthritis (RA) have an increased prevalence of multimorbidity, according to a study recently published inRMD Open.Cynthia S. Crowson, Ph.D., from the Mayo Clinic in Roch

Updated on:June 17,2024