Method for delivering immune system-stimulating drugs may enhance cancer immunotherapy

by Anne Trafton,Massachusetts Institute of TechnologyThis image depicts a tumor right after treatment with alum-bound IL12. The pink dye shows IL-12, and the yellow shows alum. Credit: Massachus

Updated on: May 08,2024 5

Method for delivering immune system-stimulating drugs may enhance cancer immunotherapy

by Anne Trafton,Massachusetts Institute of TechnologyThis image depicts a tumor right after treatment with alum-bound IL12. The pink dye shows IL-12, and the yellow shows alum. Credit: Massachus

Updated on:May 08,2024 5

Continuation vs. discontinuation of bDMARDs during the perioperative period

by Wolters Kluwer HealthCredit: Pixabay/CC0 Public DomainFor patients with rheumatic arthritis and other chronic inflammatory diseases, discontinuing biologic disease-modifying anti-rheumatic dru

Updated on: June 26,2024 4

Continuation vs. discontinuation of bDMARDs during the perioperative period

by Wolters Kluwer HealthCredit: Pixabay/CC0 Public DomainFor patients with rheumatic arthritis and other chronic inflammatory diseases, discontinuing biologic disease-modifying anti-rheumatic dru

Updated on:June 26,2024 4

The case of the missing monocyte: Scientists investigate gene that appears to protect against rheumatoid arthritis

by University of North Carolina at Chapel Hill School of MedicineThe hands of a person with arthritis. Image source: NIH.(Medical Xpress) -- An estimated 1.3 million people in the United States s

Updated on: March 24,2024 16

The case of the missing monocyte: Scientists investigate gene that appears to protect against rheumatoid arthritis

by University of North Carolina at Chapel Hill School of MedicineThe hands of a person with arthritis. Image source: NIH.(Medical Xpress) -- An estimated 1.3 million people in the United States s

Updated on:March 24,2024 16

How B cells are programmed early in life can impact long-term immune health

by Lund UniversityGraphical abstract. Credit:Immunity(2022). DOI: 10.1016/j.immuni.2022.08.018B cells and the antibodies they produce play an important role in our immune system, prot

Updated on: April 08,2024 17

How B cells are programmed early in life can impact long-term immune health

by Lund UniversityGraphical abstract. Credit:Immunity(2022). DOI: 10.1016/j.immuni.2022.08.018B cells and the antibodies they produce play an important role in our immune system, prot

Updated on:April 08,2024 17

Arthritis reported by almost one in four U.S. adults

(HealthDay)—Almost one-quarter of U.S. adults report arthritis, according to research published in the Oct. 8 issue of the U.S. Centers for Disease Control and PreventionMorbidity and Mortality

Updated on: May 08,2024 6

Arthritis reported by almost one in four U.S. adults

(HealthDay)—Almost one-quarter of U.S. adults report arthritis, according to research published in the Oct. 8 issue of the U.S. Centers for Disease Control and PreventionMorbidity and Mortality

Updated on:May 08,2024 6

Sharing of skin microbiome between children with atopic dermatitis and healthy contacts might contribute to recurrence

by National University of SingaporeGraphical abstract. Credit:Journal of Allergy and Clinical Immunology(2022). DOI: 10.1016/j.jaci.2022.01.031Patients with moderate to severe atopic

Updated on: June 12,2024 5

Sharing of skin microbiome between children with atopic dermatitis and healthy contacts might contribute to recurrence

by National University of SingaporeGraphical abstract. Credit:Journal of Allergy and Clinical Immunology(2022). DOI: 10.1016/j.jaci.2022.01.031Patients with moderate to severe atopic

Updated on:June 12,2024 5

Study aims to unravel the genetic causes of osteoarthritis

by Wellcome Trust Sanger InstituteA hip with osteoarthritis. In an X-ray of a healthy hip, the heads of the hip bone have smooth, evenly curved surfaces and there is a 'gap' between the h

Updated on: March 28,2024 16

Study aims to unravel the genetic causes of osteoarthritis

by Wellcome Trust Sanger InstituteA hip with osteoarthritis. In an X-ray of a healthy hip, the heads of the hip bone have smooth, evenly curved surfaces and there is a 'gap' between the h

Updated on:March 28,2024 16

Does body mass index impact pain in individuals with hand osteoarthritis?

by WileyCredit: Unsplash/CC0 Public DomainIn a study inArthritis & Rheumatologyof people with hand osteoarthritis, higher body mass index was associated with greater pain severity

Updated on: June 15,2024 5

Does body mass index impact pain in individuals with hand osteoarthritis?

by WileyCredit: Unsplash/CC0 Public DomainIn a study inArthritis & Rheumatologyof people with hand osteoarthritis, higher body mass index was associated with greater pain severity

Updated on:June 15,2024 5

FDA approves first interchangeable biosimilar for inflammatory diseases

(HealthDay)—The first interchangeable biosimilar product to Humira (adalimumab) was approved by the U.S. Food and Drug Administration on Oct. 15, the agency announced Monday.Cyltezo (adalimumab-adbm),

Updated on: June 17,2024 6

FDA approves first interchangeable biosimilar for inflammatory diseases

(HealthDay)—The first interchangeable biosimilar product to Humira (adalimumab) was approved by the U.S. Food and Drug Administration on Oct. 15, the agency announced Monday.Cyltezo (adalimumab-adbm),

Updated on:June 17,2024 6

Subclinical atherosclerosis noted in diffuse scleroderma

Patients with diffuse systemic sclerosis, without any clinical evidence of cardiovascular disease, have indicators of subclinical atherosclerosis, according to a study published online Aug. 16 in&nbsp

Updated on: March 24,2024 17

Subclinical atherosclerosis noted in diffuse scleroderma

Patients with diffuse systemic sclerosis, without any clinical evidence of cardiovascular disease, have indicators of subclinical atherosclerosis, according to a study published online Aug. 16 in&nbsp

Updated on:March 24,2024 17

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on: June 15,2024 4

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on:June 15,2024 4

MyD88—villain of allergies and asthma

by Lydia Goff ,Duke UniversityFlorescence microscopy image of mouse dendritic cells with mRNA-loaded blood cells.Even if you don't have allergies yourself, I guarantee you can list at

Updated on: April 20,2024 12

MyD88—villain of allergies and asthma

by Lydia Goff ,Duke UniversityFlorescence microscopy image of mouse dendritic cells with mRNA-loaded blood cells.Even if you don't have allergies yourself, I guarantee you can list at

Updated on:April 20,2024 12