A common metabolite may help treat autoimmune diseases

by Hokkaido UniversityIn mice models with adoptive transfer experimental autoimmune encephalomyelitis, treatment with itaconate (right) greatly ameliorates the effects of the disease, compared to

Updated on: May 08,2024

A common metabolite may help treat autoimmune diseases

by Hokkaido UniversityIn mice models with adoptive transfer experimental autoimmune encephalomyelitis, treatment with itaconate (right) greatly ameliorates the effects of the disease, compared to

Updated on:May 08,2024

Air pollution exposure tied to new psoriasis

by Lori SolomonLong-term exposure to air pollution is associated with the development of new psoriasis, according to a studypublishedonline July 16 inJAMA Network Open.Junhui Wu, Ph.

Updated on: July 23,2024

Air pollution exposure tied to new psoriasis

by Lori SolomonLong-term exposure to air pollution is associated with the development of new psoriasis, according to a studypublishedonline July 16 inJAMA Network Open.Junhui Wu, Ph.

Updated on:July 23,2024

Scientists identify reversible molecular defect underlying rheumatoid arthritis

by Bruce Goldman,Stanford University Medical CenterScanning electron micrograph of human T lymphocyte or T cell. Credit: NIAID/NIHIn rheumatoid arthritis, immune cells called helper T cells beha

Updated on: June 06,2024

Scientists identify reversible molecular defect underlying rheumatoid arthritis

by Bruce Goldman,Stanford University Medical CenterScanning electron micrograph of human T lymphocyte or T cell. Credit: NIAID/NIHIn rheumatoid arthritis, immune cells called helper T cells beha

Updated on:June 06,2024

MyD88—villain of allergies and asthma

by Lydia Goff ,Duke UniversityFlorescence microscopy image of mouse dendritic cells with mRNA-loaded blood cells.Even if you don't have allergies yourself, I guarantee you can list at

Updated on: April 20,2024

MyD88—villain of allergies and asthma

by Lydia Goff ,Duke UniversityFlorescence microscopy image of mouse dendritic cells with mRNA-loaded blood cells.Even if you don't have allergies yourself, I guarantee you can list at

Updated on:April 20,2024

Could CAR-T cell therapy improve kidney transplants?

by Susan Buckles, Mayo Clinic News NetworkCredit:Kidney International(2024). DOI: 10.1016/j.kint.2024.02.008Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) could provide a re

Updated on: April 28,2024

Could CAR-T cell therapy improve kidney transplants?

by Susan Buckles, Mayo Clinic News NetworkCredit:Kidney International(2024). DOI: 10.1016/j.kint.2024.02.008Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) could provide a re

Updated on:April 28,2024

CAR-T therapy modifications provide new promise for cancer immunotherapies

by King's College LondonCredit: CC0 Public DomainNew research led by Dr. John Maher, from the School of Cancer & Pharmaceutical Sciences, working for Leucid Bio and with biotech company L

Updated on: April 09,2024

CAR-T therapy modifications provide new promise for cancer immunotherapies

by King's College LondonCredit: CC0 Public DomainNew research led by Dr. John Maher, from the School of Cancer & Pharmaceutical Sciences, working for Leucid Bio and with biotech company L

Updated on:April 09,2024

A COVID-19 biomarker: Low blood levels of sphingosine predict symptomatic infections

by Medical University of South CarolinaImage of the ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV). Credit: CDCResearchers remain perplexed as to why some patients

Updated on: April 13,2024

A COVID-19 biomarker: Low blood levels of sphingosine predict symptomatic infections

by Medical University of South CarolinaImage of the ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV). Credit: CDCResearchers remain perplexed as to why some patients

Updated on:April 13,2024

New mechanism fueling brain metastasis discovered at Wistar

by The Wistar InstituteDr. Qing Chen of The Wistar Institute Credit: The Wistar InstituteScientists at The Wistar Institute described a novel mechanism through which astrocytes, the most abundant

Updated on: May 05,2024

New mechanism fueling brain metastasis discovered at Wistar

by The Wistar InstituteDr. Qing Chen of The Wistar Institute Credit: The Wistar InstituteScientists at The Wistar Institute described a novel mechanism through which astrocytes, the most abundant

Updated on:May 05,2024

Can a DNA construction kit replace expensive antibody medication?

by KU LeuvenCredit: CC0 Public DomainResearchers at KU Leuven in Belgium have developed a technique to make sheep produce new antibodies simply by injecting the DNA building blocks. This approach

Updated on: April 15,2024

Can a DNA construction kit replace expensive antibody medication?

by KU LeuvenCredit: CC0 Public DomainResearchers at KU Leuven in Belgium have developed a technique to make sheep produce new antibodies simply by injecting the DNA building blocks. This approach

Updated on:April 15,2024

Increased insulin resistance in rheumatoid arthritis

(HealthDay)—Patients with rheumatoid arthritis (RA) have elevated insulin resistance (IR), but this is not associated with increased atherosclerosis risk, according to a study published online Dec. 10

Updated on: April 08,2024

Increased insulin resistance in rheumatoid arthritis

(HealthDay)—Patients with rheumatoid arthritis (RA) have elevated insulin resistance (IR), but this is not associated with increased atherosclerosis risk, according to a study published online Dec. 10

Updated on:April 08,2024

The secret lives of T cells: They derive energy from a master regulator that has been poorly understood, until now

by Delthia Ricks , Medical XpressIn vitro modeling of Teff STAT5 responses. (A) WT CD4+ T cells were cultured with or without blocking anti-mouse IL-2/IL-2R antibodies and/or human IL-2. Flow cytometr

Updated on: May 06,2024

The secret lives of T cells: They derive energy from a master regulator that has been poorly understood, until now

by Delthia Ricks , Medical XpressIn vitro modeling of Teff STAT5 responses. (A) WT CD4+ T cells were cultured with or without blocking anti-mouse IL-2/IL-2R antibodies and/or human IL-2. Flow cytometr

Updated on:May 06,2024

Immune receptor provides protective immunity against Group A Streptococcus

by Osaka UniversityFig. 1: The mechanism by which group A Streptococcus (GAS) evades the immune system. The immune receptor Mincle recognizes MGDG, an immunoactivating lipid present on GAS, and t

Updated on: April 16,2024

Immune receptor provides protective immunity against Group A Streptococcus

by Osaka UniversityFig. 1: The mechanism by which group A Streptococcus (GAS) evades the immune system. The immune receptor Mincle recognizes MGDG, an immunoactivating lipid present on GAS, and t

Updated on:April 16,2024