CAR T cells suppress GI solid tumor cells, without toxicity to healthy tissue, in preclinical research

by University of PennsylvaniaCDH17 CARTs attack tumor but spare normal tissue. Credit: Penn MedicineChimeric antigen receptor (CAR) T cells can be remarkably effective in treating leukemias and l

Updated on: April 09,2024

CAR T cells suppress GI solid tumor cells, without toxicity to healthy tissue, in preclinical research

by University of PennsylvaniaCDH17 CARTs attack tumor but spare normal tissue. Credit: Penn MedicineChimeric antigen receptor (CAR) T cells can be remarkably effective in treating leukemias and l

Updated on:April 09,2024

Pain and fatigue in rheumatoid arthritis tied to sitting and standing time

For patients with rheumatoid arthritis (RA), pain and fatigue may both cause and be caused by more sitting time and less standing time, according to a study published in the October issue ofRheu

Updated on: June 17,2024

Pain and fatigue in rheumatoid arthritis tied to sitting and standing time

For patients with rheumatoid arthritis (RA), pain and fatigue may both cause and be caused by more sitting time and less standing time, according to a study published in the October issue ofRheu

Updated on:June 17,2024

Methotrexate improves function in people with knee OA after three months

by American College of RheumatologyCredit: CC0 Public DomainA new study presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that after three months of t

Updated on: May 13,2024

Methotrexate improves function in people with knee OA after three months

by American College of RheumatologyCredit: CC0 Public DomainA new study presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that after three months of t

Updated on:May 13,2024

Arthritis reported by almost one in four U.S. adults

(HealthDay)—Almost one-quarter of U.S. adults report arthritis, according to research published in the Oct. 8 issue of the U.S. Centers for Disease Control and PreventionMorbidity and Mortality

Updated on: May 08,2024

Arthritis reported by almost one in four U.S. adults

(HealthDay)—Almost one-quarter of U.S. adults report arthritis, according to research published in the Oct. 8 issue of the U.S. Centers for Disease Control and PreventionMorbidity and Mortality

Updated on:May 08,2024

Study of infants and young children shows that offspring develop normally in mothers with rheumatic disease

by European League Against Rheumatism (EULAR)Credit: CC0 Public DomainAnkylosing spondylitis (AS) is a complex chronic inflammatory disease of the spine with involvement of the sacroiliac joints. Over

Updated on: June 26,2024

Study of infants and young children shows that offspring develop normally in mothers with rheumatic disease

by European League Against Rheumatism (EULAR)Credit: CC0 Public DomainAnkylosing spondylitis (AS) is a complex chronic inflammatory disease of the spine with involvement of the sacroiliac joints. Over

Updated on:June 26,2024

Could CAR-T cell therapy improve kidney transplants?

by Susan Buckles, Mayo Clinic News NetworkCredit:Kidney International(2024). DOI: 10.1016/j.kint.2024.02.008Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) could provide a re

Updated on: April 28,2024

Could CAR-T cell therapy improve kidney transplants?

by Susan Buckles, Mayo Clinic News NetworkCredit:Kidney International(2024). DOI: 10.1016/j.kint.2024.02.008Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) could provide a re

Updated on:April 28,2024

Prevalence of gout increases with increasing BMI

Having an increased body mass index correlates with increased prevalence of gout in adults, according to study published online July 6 inArthritis Care & Research.(HealthDay) -- Having an in

Updated on: April 08,2024

Prevalence of gout increases with increasing BMI

Having an increased body mass index correlates with increased prevalence of gout in adults, according to study published online July 6 inArthritis Care & Research.(HealthDay) -- Having an in

Updated on:April 08,2024

How does vaccination thwart pneumococcal infection? Animal model uncovers 'capture and kill' scenario

by Delthia Ricks , Medical XpressRepresentative IVM imaging of vaccine-activated capture of ST865 pneumococci in the liver sinusoids. Pneumococci, green; KCs, red; ECs, cyan; neutrophils, magenta. Cre

Updated on: March 07,2024

How does vaccination thwart pneumococcal infection? Animal model uncovers 'capture and kill' scenario

by Delthia Ricks , Medical XpressRepresentative IVM imaging of vaccine-activated capture of ST865 pneumococci in the liver sinusoids. Pneumococci, green; KCs, red; ECs, cyan; neutrophils, magenta. Cre

Updated on:March 07,2024

COVID-19 can cause severe inflammation in the brain

by Albert Ludwigs University of FreiburgGraphical Abstract. Credit:Immunity(2021). DOI: 10.1016/j.immuni.2021.06.002Both during and after infection with the Coronavirus SARS-CoV-2, pa

Updated on: April 10,2024

COVID-19 can cause severe inflammation in the brain

by Albert Ludwigs University of FreiburgGraphical Abstract. Credit:Immunity(2021). DOI: 10.1016/j.immuni.2021.06.002Both during and after infection with the Coronavirus SARS-CoV-2, pa

Updated on:April 10,2024

Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to

Updated on: September 07,2024

Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to

Updated on:September 07,2024

Triple contrast method for computed tomography diagnostics of cartilage injuries

by University of Eastern FinlandCredit: Pixabay/CC0 Public DomainPost-traumatic osteoarthritis (PTOA) is a joint disease associated with the gradual erosion of cartilage covering the ends of arti

Updated on: May 26,2024

Triple contrast method for computed tomography diagnostics of cartilage injuries

by University of Eastern FinlandCredit: Pixabay/CC0 Public DomainPost-traumatic osteoarthritis (PTOA) is a joint disease associated with the gradual erosion of cartilage covering the ends of arti

Updated on:May 26,2024

Adults with psoriasis more likely to have rheumatoid arthritis

(HealthDay)—Adults with psoriasis have an increased likelihood of having rheumatoid arthritis (RA) compared with adults without psoriasis, according to a study published online June 15 in theJou

Updated on: May 08,2024

Adults with psoriasis more likely to have rheumatoid arthritis

(HealthDay)—Adults with psoriasis have an increased likelihood of having rheumatoid arthritis (RA) compared with adults without psoriasis, according to a study published online June 15 in theJou

Updated on:May 08,2024