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Immunology & Rheumatology
Focuses on rheumatic and immune diseases.
Sub Categories on Immunology & Rheumatology
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Novel checkpoint molecule of natural killer cell anti-tumor immunity revealed

Novel checkpoint molecule of natural killer cell anti-tumor immunity revealed

by Li Yuan,Chinese Academy of SciencesFig. 1. TIPE2 expression correlates with NK cell maturation in both mice and humans.(A) TIPE2 expression of purified splenic NK cells from 2-, 4-, 6-, or 10

Novel checkpoint molecule of natural killer cell anti-tumor immunity revealed

by Li Yuan,Chinese Academy of SciencesFig. 1. TIPE2 expression correlates with NK cell maturation in both mice and humans.(A) TIPE2 expression of purified splenic NK cells from 2-, 4-, 6-, or 10
Improvements in RA disease activity with bariatric sx

Improvements in RA disease activity with bariatric sx

(HealthDay)—For patients with rheumatoid arthritis (RA), bariatric surgery-associated weight loss correlates with lower disease activity, decreased serum inflammatory markers, and less RA-related medi

Improvements in RA disease activity with bariatric sx

(HealthDay)—For patients with rheumatoid arthritis (RA), bariatric surgery-associated weight loss correlates with lower disease activity, decreased serum inflammatory markers, and less RA-related medi
VAV1 gene mutations trigger T-cell tumors in mice

VAV1 gene mutations trigger T-cell tumors in mice

by University of TsukubaCredit: CC0 Public DomainLife is an exquisite orchestration of growth and change, with checks and balances that fine-tune complex entwined interactions, both intrinsic and

VAV1 gene mutations trigger T-cell tumors in mice

by University of TsukubaCredit: CC0 Public DomainLife is an exquisite orchestration of growth and change, with checks and balances that fine-tune complex entwined interactions, both intrinsic and
How IL-33 plays a key role in enabling the marathon runners of the immune system

How IL-33 plays a key role in enabling the marathon runners of the immune system

by University of BaselGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.01.029When it comes to chronic infections and cancer, a particular type of immune cell play

How IL-33 plays a key role in enabling the marathon runners of the immune system

by University of BaselGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.01.029When it comes to chronic infections and cancer, a particular type of immune cell play
Lower doses of rheumatoid arthritis drugs may work for some

Lower doses of rheumatoid arthritis drugs may work for some

by Amy Norton, Healthday ReporterStudy found many patients with early stage disease stayed in remission with less medication.(HealthDay)—Some people in the early stages of rheumatoid arthritis may be

Lower doses of rheumatoid arthritis drugs may work for some

by Amy Norton, Healthday ReporterStudy found many patients with early stage disease stayed in remission with less medication.(HealthDay)—Some people in the early stages of rheumatoid arthritis may be
Immune receptor provides protective immunity against Group A Streptococcus

Immune receptor provides protective immunity against Group A Streptococcus

by Osaka UniversityFig. 1: The mechanism by which group A Streptococcus (GAS) evades the immune system. The immune receptor Mincle recognizes MGDG, an immunoactivating lipid present on GAS, and t

Immune receptor provides protective immunity against Group A Streptococcus

by Osaka UniversityFig. 1: The mechanism by which group A Streptococcus (GAS) evades the immune system. The immune receptor Mincle recognizes MGDG, an immunoactivating lipid present on GAS, and t
A COVID-19 biomarker: Low blood levels of sphingosine predict symptomatic infections

A COVID-19 biomarker: Low blood levels of sphingosine predict symptomatic infections

by Medical University of South CarolinaImage of the ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV). Credit: CDCResearchers remain perplexed as to why some patients

A COVID-19 biomarker: Low blood levels of sphingosine predict symptomatic infections

by Medical University of South CarolinaImage of the ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV). Credit: CDCResearchers remain perplexed as to why some patients
Many risk factors contribute to worsening of quality of life in people with knee OA

Many risk factors contribute to worsening of quality of life in people with knee OA

by University of Eastern FinlandCredit: CC0 Public DomainA new study from the University of Eastern Finland shows that the health-related quality of life of most people who have had or have a hig

Many risk factors contribute to worsening of quality of life in people with knee OA

by University of Eastern FinlandCredit: CC0 Public DomainA new study from the University of Eastern Finland shows that the health-related quality of life of most people who have had or have a hig
In veterans with RA, PTSD worsens disease activity

In veterans with RA, PTSD worsens disease activity

For U.S. veterans with rheumatoid arthritis, a diagnosis of posttraumatic stress disorder is associated with worse patient-reported outcomes and tender joint counts, according to a study published onl

In veterans with RA, PTSD worsens disease activity

For U.S. veterans with rheumatoid arthritis, a diagnosis of posttraumatic stress disorder is associated with worse patient-reported outcomes and tender joint counts, according to a study published onl
A leap forward in research on CAR T cell therapy

A leap forward in research on CAR T cell therapy

by University of HelsinkiCredit: CC0 Public DomainIn cancer immunotherapy, cells in the patient's own immune system are activated to attack cancer cells. CAR T cell therapy has been one of th

A leap forward in research on CAR T cell therapy

by University of HelsinkiCredit: CC0 Public DomainIn cancer immunotherapy, cells in the patient's own immune system are activated to attack cancer cells. CAR T cell therapy has been one of th
New study reveals specialization of immune cells in different tissues

New study reveals specialization of immune cells in different tissues

byKarolinska InstitutetJohan Sandberg. Credit: Karolinska InstitutetA new study from Karolinska Institutet has mapped how MAIT cells, which play an important role in the body's defense again

New study reveals specialization of immune cells in different tissues

byKarolinska InstitutetJohan Sandberg. Credit: Karolinska InstitutetA new study from Karolinska Institutet has mapped how MAIT cells, which play an important role in the body's defense again
Proportion of adults diagnosed with inflammatory arthritis in England has increased by more than 40%

Proportion of adults diagnosed with inflammatory arthritis in England has increased by more than 40%

by Keele UniversityPercentage of patients with at least 1 Read/SNOMED code for RA who meet the diagnosis algorithm. Panel A = percentage of patients ever receiving an RA Read/SNOMED code that mee

Proportion of adults diagnosed with inflammatory arthritis in England has increased by more than 40%

by Keele UniversityPercentage of patients with at least 1 Read/SNOMED code for RA who meet the diagnosis algorithm. Panel A = percentage of patients ever receiving an RA Read/SNOMED code that mee