A key gene modifies regulatory T cells to fine-tune the immune response

by Salk InstituteA histology image showing inflammation in colon epithelium. Weakening of regulatory T cell function induces infiltration of immune cells (small blue dots) into colon epithelium (

Updated on: May 07,2024 18

A key gene modifies regulatory T cells to fine-tune the immune response

by Salk InstituteA histology image showing inflammation in colon epithelium. Weakening of regulatory T cell function induces infiltration of immune cells (small blue dots) into colon epithelium (

Updated on:May 07,2024 18

MyD88—villain of allergies and asthma

by Lydia Goff ,Duke UniversityFlorescence microscopy image of mouse dendritic cells with mRNA-loaded blood cells.Even if you don't have allergies yourself, I guarantee you can list at

Updated on: April 20,2024 12

MyD88—villain of allergies and asthma

by Lydia Goff ,Duke UniversityFlorescence microscopy image of mouse dendritic cells with mRNA-loaded blood cells.Even if you don't have allergies yourself, I guarantee you can list at

Updated on:April 20,2024 12

Subclinical atherosclerosis noted in diffuse scleroderma

Patients with diffuse systemic sclerosis, without any clinical evidence of cardiovascular disease, have indicators of subclinical atherosclerosis, according to a study published online Aug. 16 in&nbsp

Updated on: March 24,2024 17

Subclinical atherosclerosis noted in diffuse scleroderma

Patients with diffuse systemic sclerosis, without any clinical evidence of cardiovascular disease, have indicators of subclinical atherosclerosis, according to a study published online Aug. 16 in&nbsp

Updated on:March 24,2024 17

Weight loss predicts mortality in rheumatoid arthritis

(HealthDay)—Weight loss is a strong predictor of mortality in patients with rheumatoid arthritis (RA), according to a study published online June 26 inArthritis & Rheumatology.Joshua F. Bake

Updated on: April 08,2024 16

Weight loss predicts mortality in rheumatoid arthritis

(HealthDay)—Weight loss is a strong predictor of mortality in patients with rheumatoid arthritis (RA), according to a study published online June 26 inArthritis & Rheumatology.Joshua F. Bake

Updated on:April 08,2024 16

The secret lives of T cells: They derive energy from a master regulator that has been poorly understood, until now

by Delthia Ricks , Medical XpressIn vitro modeling of Teff STAT5 responses. (A) WT CD4+ T cells were cultured with or without blocking anti-mouse IL-2/IL-2R antibodies and/or human IL-2. Flow cytometr

Updated on: May 06,2024 20

The secret lives of T cells: They derive energy from a master regulator that has been poorly understood, until now

by Delthia Ricks , Medical XpressIn vitro modeling of Teff STAT5 responses. (A) WT CD4+ T cells were cultured with or without blocking anti-mouse IL-2/IL-2R antibodies and/or human IL-2. Flow cytometr

Updated on:May 06,2024 20

Researchers discover potential new approach to treating psoriatic joint inflammation

by UC DavisCredit: CC0 Public DomainAn international team of researchers, led by UC Davis Health, has developed a new therapeutic approach to treating psoriatic arthritis, a chronic inflammatory

Updated on: June 17,2024 7

Researchers discover potential new approach to treating psoriatic joint inflammation

by UC DavisCredit: CC0 Public DomainAn international team of researchers, led by UC Davis Health, has developed a new therapeutic approach to treating psoriatic arthritis, a chronic inflammatory

Updated on:June 17,2024 7

T cell response not critical for immune memory to SARS-CoV-2 or recovery from COVID-19

by American Society for MicrobiologyTransmission electron micrograph of SARS-CoV-2 virus particles isolated from a patient. Credit: NIAIDNew research conducted in monkeys reveals that T cells are

Updated on: May 08,2024 6

T cell response not critical for immune memory to SARS-CoV-2 or recovery from COVID-19

by American Society for MicrobiologyTransmission electron micrograph of SARS-CoV-2 virus particles isolated from a patient. Credit: NIAIDNew research conducted in monkeys reveals that T cells are

Updated on:May 08,2024 6

Study of infants and young children shows that offspring develop normally in mothers with rheumatic disease

by European League Against Rheumatism (EULAR)Credit: CC0 Public DomainAnkylosing spondylitis (AS) is a complex chronic inflammatory disease of the spine with involvement of the sacroiliac joints. Over

Updated on: June 26,2024 4

Study of infants and young children shows that offspring develop normally in mothers with rheumatic disease

by European League Against Rheumatism (EULAR)Credit: CC0 Public DomainAnkylosing spondylitis (AS) is a complex chronic inflammatory disease of the spine with involvement of the sacroiliac joints. Over

Updated on:June 26,2024 4

New prediction model could help inform patients of their risks of having shoulder replacement surgery

byUniversity of OxfordCredit: Pixabay/CC0 Public DomainA new model to predict the risk of serious complications after shoulder replacement surgery has been developed in a collaboration between r

Updated on: August 08,2024 0

New prediction model could help inform patients of their risks of having shoulder replacement surgery

byUniversity of OxfordCredit: Pixabay/CC0 Public DomainA new model to predict the risk of serious complications after shoulder replacement surgery has been developed in a collaboration between r

Updated on:August 08,2024 0

Severe reaction to pneumococcal vaccines in patients with CAPS

(HealthDay)—Pneumococcal vaccines can trigger a severe local and systemic inflammatory reaction in patients with cryopyrin-associated periodic syndromes (CAPS), according to a study published in the F

Updated on: April 17,2024 13

Severe reaction to pneumococcal vaccines in patients with CAPS

(HealthDay)—Pneumococcal vaccines can trigger a severe local and systemic inflammatory reaction in patients with cryopyrin-associated periodic syndromes (CAPS), according to a study published in the F

Updated on:April 17,2024 13

CVD risk factors tied to disease activity, disability in RA

(HealthDay)—Cardiovascular disease (CVD) risk factors alone, or in combination, are associated with higher disease activity and disability in rheumatoid arthritis (RA), according to a study recently p

Updated on: June 01,2024 3

CVD risk factors tied to disease activity, disability in RA

(HealthDay)—Cardiovascular disease (CVD) risk factors alone, or in combination, are associated with higher disease activity and disability in rheumatoid arthritis (RA), according to a study recently p

Updated on:June 01,2024 3

ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis

by Osaka UniversityE-NTPD8 in colonic epithelial cells maintains gut homeostasis through the hydrolysis of luminal ATP produced by commensal bacteria (left). An increased level of luminal ATP cau

Updated on: April 08,2024 19

ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis

by Osaka UniversityE-NTPD8 in colonic epithelial cells maintains gut homeostasis through the hydrolysis of luminal ATP produced by commensal bacteria (left). An increased level of luminal ATP cau

Updated on:April 08,2024 19