Novel checkpoint molecule of natural killer cell anti-tumor immunity revealed

by Li Yuan,Chinese Academy of SciencesFig. 1. TIPE2 expression correlates with NK cell maturation in both mice and humans.(A) TIPE2 expression of purified splenic NK cells from 2-, 4-, 6-, or 10

Updated on: April 20,2024

Novel checkpoint molecule of natural killer cell anti-tumor immunity revealed

by Li Yuan,Chinese Academy of SciencesFig. 1. TIPE2 expression correlates with NK cell maturation in both mice and humans.(A) TIPE2 expression of purified splenic NK cells from 2-, 4-, 6-, or 10

Updated on:April 20,2024

Low back pain? Don't blame the weather

by WileyCloud in Nepali sky. Credit: WikipediaAustralian researchers reveal that sudden, acute episodes of low back pain are not linked to weather conditions such as temperature, humidity, air pr

Updated on: March 24,2024

Low back pain? Don't blame the weather

by WileyCloud in Nepali sky. Credit: WikipediaAustralian researchers reveal that sudden, acute episodes of low back pain are not linked to weather conditions such as temperature, humidity, air pr

Updated on:March 24,2024

TLK protein inhibition activates the innate immune system

by Institute for Research in Biomedicine - IRBCancer cells with TLK inhibition show replication intermediates (green) at chromosome ends (red). Credit: IRB BarcelonaTousled-like kinases (TLKs) are a p

Updated on: April 24,2024

TLK protein inhibition activates the innate immune system

by Institute for Research in Biomedicine - IRBCancer cells with TLK inhibition show replication intermediates (green) at chromosome ends (red). Credit: IRB BarcelonaTousled-like kinases (TLKs) are a p

Updated on:April 24,2024

Scientists identify reversible molecular defect underlying rheumatoid arthritis

by Bruce Goldman,Stanford University Medical CenterScanning electron micrograph of human T lymphocyte or T cell. Credit: NIAID/NIHIn rheumatoid arthritis, immune cells called helper T cells beha

Updated on: June 06,2024

Scientists identify reversible molecular defect underlying rheumatoid arthritis

by Bruce Goldman,Stanford University Medical CenterScanning electron micrograph of human T lymphocyte or T cell. Credit: NIAID/NIHIn rheumatoid arthritis, immune cells called helper T cells beha

Updated on:June 06,2024

Inflammatory link discovered between arthritis and heart valve disease

by Walter and Eliza Hall InstituteAustralian researchers have used models to identify a potential link between excess production of inflammatory proteins that cause rheumatoid arthritis and the d

Updated on: March 24,2024

Inflammatory link discovered between arthritis and heart valve disease

by Walter and Eliza Hall InstituteAustralian researchers have used models to identify a potential link between excess production of inflammatory proteins that cause rheumatoid arthritis and the d

Updated on:March 24,2024

How gum disease aggravates chronic obstructive pulmonary disease

by American Society for MicrobiologyCredit: CC0 Public DomainSevere gum disease has been linked to the progression of chronic obstructive pulmonary disease, or COPD, but an understanding of how t

Updated on: March 07,2024

How gum disease aggravates chronic obstructive pulmonary disease

by American Society for MicrobiologyCredit: CC0 Public DomainSevere gum disease has been linked to the progression of chronic obstructive pulmonary disease, or COPD, but an understanding of how t

Updated on:March 07,2024

Lupus, rheumatoid arthritis tied to higher risk for adverse obstetric, birth outcomes

by Lori SolomonWomen with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) and their infants experience higher rates of adverse obstetric and birth outcomes, according to a study publis

Updated on: June 15,2024

Lupus, rheumatoid arthritis tied to higher risk for adverse obstetric, birth outcomes

by Lori SolomonWomen with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) and their infants experience higher rates of adverse obstetric and birth outcomes, according to a study publis

Updated on:June 15,2024

A COVID-19 biomarker: Low blood levels of sphingosine predict symptomatic infections

by Medical University of South CarolinaImage of the ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV). Credit: CDCResearchers remain perplexed as to why some patients

Updated on: April 13,2024

A COVID-19 biomarker: Low blood levels of sphingosine predict symptomatic infections

by Medical University of South CarolinaImage of the ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV). Credit: CDCResearchers remain perplexed as to why some patients

Updated on:April 13,2024

Could CAR-T cell therapy improve kidney transplants?

by Susan Buckles, Mayo Clinic News NetworkCredit:Kidney International(2024). DOI: 10.1016/j.kint.2024.02.008Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) could provide a re

Updated on: April 28,2024

Could CAR-T cell therapy improve kidney transplants?

by Susan Buckles, Mayo Clinic News NetworkCredit:Kidney International(2024). DOI: 10.1016/j.kint.2024.02.008Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) could provide a re

Updated on:April 28,2024

Innovative software improves chronic rheumatic disease care

(HealthDay)—For patients with chronic rheumatic disease, innovative software that aggregates, stores, and displays information can improve quality of care, according to research published online Nov.

Updated on: April 08,2024

Innovative software improves chronic rheumatic disease care

(HealthDay)—For patients with chronic rheumatic disease, innovative software that aggregates, stores, and displays information can improve quality of care, according to research published online Nov.

Updated on:April 08,2024

A better test for the tumor-targeting of CAR-T therapies

by Ludwig Institute for Cancer ResearchCredit: CC0 Public DomainLudwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-r

Updated on: April 24,2024

A better test for the tumor-targeting of CAR-T therapies

by Ludwig Institute for Cancer ResearchCredit: CC0 Public DomainLudwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-r

Updated on:April 24,2024

Proportion of adults diagnosed with inflammatory arthritis in England has increased by more than 40%

by Keele UniversityPercentage of patients with at least 1 Read/SNOMED code for RA who meet the diagnosis algorithm. Panel A = percentage of patients ever receiving an RA Read/SNOMED code that mee

Updated on: March 28,2024

Proportion of adults diagnosed with inflammatory arthritis in England has increased by more than 40%

by Keele UniversityPercentage of patients with at least 1 Read/SNOMED code for RA who meet the diagnosis algorithm. Panel A = percentage of patients ever receiving an RA Read/SNOMED code that mee

Updated on:March 28,2024